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양수과다증, 심장기형을 동반한 Holoprosencephaly 1 예
최종현,승경록 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.7 No.-
Holoprosencephaly is a rare congenital disorder stemming from failure of normal forebrain development and cleavage during early embryonic development. A case of holoprosencephaly associated with hydramnios and heart anomaly is presented with a brief review of its literatures.
승경록 건국대학교 의과학연구소 1992 건국의과학학술지 Vol.2 No.-
To evaluate the effectiveness of ICR mouse embryos for qaulity control of human IVF program, series of experiments was conducted. In experiment 1, mouse ova were inseminated in vitro in T6 and Ham's F-10 media which were supplemented with 100μM EDTA and 3㎎/ml BSA, respectively and further growth was observed. In experiment 2, in vivo fertilized 2-cell stage ICR mouse embryos were collected in each previously mentioned media and further growth was observed. After comparing datas taken from experiment 1 and 2, following results were obtained. 1. In experiment 1, fertilization and growth rates were compared and statistically significant results were obtained between the datas taken from T6 and Ham's F-10 medium(p<0.001) 2. In experiment 2, growth and hatching rates were compared and stastically significant results were obatined between the datas taken from T6 and Ham's F-10 medium(p<0.001) 3. IN experiment 1 and 2, T6 medium revealed better result than Ham's F-10 medium especially in case of early embryonic development. 4. To control the culture condition with ICR mouse embryos except culture medium itself, chemically defined medium which does not contain hypoxanthine may be preferable.
임신 및 출산후 흰쥐 자궁의 Catecholamine 형광물질의 변화에 관한 연구
승경록,서영석,엄창섭 고려대학교 의과대학 1991 고려대 의대 잡지 Vol.28 No.1
This study was undertaken to investigate the pattern of distribution of adrenergic nerves in normal virgin, and the relatioships between the functions of adrenergic nerve and the female sex hormones changed peculiarly during pregnancy and post partum as previously reported by many authors. The reproductive organs were fixed in mixture of 4% formaldehyde and 0.5% glutaraldehyde and processed for fluorescent microscopy to show the catecholamine concentrations in nulliparous, pregnant(5, 10, 15 and 20 days), puerpheral(3, 7 and 15 days),and primiparous (30 to 45 days after parturition) rats. The result obtained in this investigation are summarized as followings. 1. In virgin uteri, catecholamine-fluorescence was visible intensely in the wall of vessels and their surrounding connective tissue and less intensely in myometrium than the vessels in all regions of reproductive tract. The intensity of fluorescence was higher In uterine cervix and tubal end of uterine horn than the main part of uterine horn. 2. In the pregnant uteri, the intensities of fluorescence did not changed at 5 days of pregnancy, but decreased gradually from 10 days to 15 days of pregnancy, and disappeared atmost completely in myometrium and small vessels except some of large vessels in perimetrium during the late pregnancy. 3. In lactating rats after parturition, the fluorescence was increased rapidly and almost completely restored by 15 days after parturition. 4. In the parous uteri at more than 30 days after parturition, the fluorescence showed slightly more intense than that in the nulliparous uteri. The above findings suggest that the alterations of catecholamine-fluorescence are much removed from the peculiar characteristic changes of the female sex hormonal levels during pregnancy and post partum. It is concluded that the alterations of catecholamine-fluorescence closely relate with the quantitative changes of uterine tissue during pregnancy and post partum, and having the experience of pregnancy and parturition, the uterus attain to maturity.
승경록,최종현 건국대학교 의과학연구소 1997 건국의과학학술지 Vol.7 No.-
From January 1991 to December 1996, we studied the 34 cases of corpus luteal cyst rupture. Ruptured corpus luteal cyst can result in serious intraperitoneal hemorrhage and sometimes emergency is needed to control bleeding. The analysed clinical results were as follows: 1. In the age distribution, the youngest was 18 years old woman and the oldest was 43 years old woman and 20.6% occurred between 26 and 30 years old. 2. In 26(76.4%) of 34 case, the interval from LMP to operation was within 60 days. 3. The time interval from the development of symptoms and signs to operation was 7 days in 28(82.4%) of 34 cases. 4. The total number of cases, associated with pregnancy, were 6 cases, And 3 cases were ectopic pregnancies. 5. The strongly suspected predisposing factor was increased abdominal pressure. 6. The most common clinical symptom was low abdominal pain(88.2%) and the most common physical finding was low abdominal tenderness(76.5%) 7. The right ovary was affected in 20 cases(58.8%) and left in 14 cases(41.2%). 8. All the pregnant cases(6cases) were terminated. 9. Estimated blood loss was within 500㏄ in 26 cases(76.5%). 10. The most commonly performed operative procedure was wedge resection(67.7%).