강도별 운동 전·후 혈청 LDH, 및 CK의 활성도 변화

임용택,송분도,이충영,박명수 한국스포츠리서치 2005 한국 스포츠 리서치 Vol.16 No.2

The purpose of this study was to investigate the changes of Creatine Kinase(CK) and Lactate Dehydrogenase(LDH) activity following different exercise intensities. Each subject(N=G) performed 30min's running with different exercise intensities- 10% VO₂max, 60%VO₂max, 80VO₂max - using treadmill. To measure the blood concentration of CK and LDH, we collected blood three times - pre-exercise, post-exercise and 30min after cessation of exercise. Using this experimental method. following results were obtained; First, There was significant difference between pre- and post-exercise CK concentration in 40%VO₂max exercise group and 60%VO₂max exercise group(p<.05), but no significant difference in 80%VO₂max exercise group. Second, There was no significant difference between pre- and post-exercise LDH concentration in 40%VO₂max exercise group and 60%VO₂max exercise group. but significant difference in 80%VO₂max exercise group. This result suggested that the concentration of CK and LDH following exercise depend on exercise intensities.

운동생리학 : 운동강도에 따른 탈진 운동이 혈중 5-HT 와 도파민의 농도에 미치는 영향

김성수(SungSooKim),송분도(BunDoSong),라성민(SeongMinRa),신말순(MalSoonShin),이명화(MyongHwaLee),윤범철(BumChulYoon) 한국체육학회 2001 한국체육학회지 Vol.40 No.3

본 연구는 운동강도에 따른 중추피로의 양상을 비교하기 위해 피로를 유발하는 탈진운동을 고강도와 중강도로 구분하여 5-HT와 도파민 농도 변화를 비교하고, 탈진운동 후 회복기에서의 5-HT와 도파민의 변화 양상을 살펴보고자 하였다. 체중 250∼300g인 sprague-Dawley계 수컷 흰쥐 70마리를 사용하여 1주간의 적응 훈련을 실시한 후 무선 할당하여 운동군 60마리로 분류하였다. 운동군은 운동강도에 따라 고강도 운동군과 중강도 운동군으로 나누고 각각 운동 직후군, 회복기 10분군, 회복기 60분군에 10마리씩 할당하였다. 고강도의 탈진운동은 40m/min, 20% grade의 강도로 탈진 시까지 주행시키고, 중강도의 운동은 25m/min, 0% grade의 강도로 주행시킴으로써 피로를 유발하게 하였다. 흰쥐를 대상으로 중강도와 고강도 탈진운동을 실시한 후, 각 운동강도별로 탈진 운동전과 운동직후, 회복기 10분, 회복기 60분의 시간 경과에 따른 유리지방산과 5-HT 및 도파민의 변화 양상을 알아본 결과는 다음과 같다.1. 중강도 탈진운동 집단에서 유리 지방산의 평균이 운동직후 감소하였고, 회복기 10분, 60분에 급격한 증가를 보였다. 고강도 탈진운동 집단에서는 유리 지방산의 평균이 시간경과에 따라 유리 지방산 농도가 지속적으로 증가하였다. 운동 전, 운동직후, 회복기 10분, 회복기 60분의 시간별 차이도 유의하였으며(p=0.001), 운동 시간별 차이의 사후검정 결과 회복기 60분과 운동직후간 유의한 차이가 있었다.2. 혈장 5-HT는 중강도 탈진운동 집단이 고강도 탈진운동 집단에 비해서 유의한 증가를 보였고, 두 집단 모두 운동 시간과 휴식 시간의 시점에 따라 유의한 증가를 보였다. 중강도 탈진운동 집단에서 5-HT가 시점에 따라 농도가 서서히 증가하다가 탈진시보다 회복기 10분에서 더 증가되었으며 회복기 60분에서 급격히 감소하는 경향을 보였다. 고강도 탈진운동 집단에서는 통계적으로 유의하지는 않지만 시점에 따라 5-HT농도가 지속적으로 증가하는 경향을 보였다. 3. 도파민은 중강도 탈진운동 집단에서 중추 피로가 유발됨에 따라 도파민의 농도가 유의하게 탈진 시점에서 급격히 증가하였다가 회복기 10분부터 급격히 감소하였다. 고강도 탈진 운동 집단에서는 탈진 시점에서 감소하였다가 회복기 10분부터 급격한 증가를 보였고 이후 감소하였다.도파민의 농도 변화에서는 강도에 따른 유의한 차이는 없었으나 시점에 따라 유의한 차이를 보였다(p=0.05). 사후 검정 결과 회복기 10분과 회복기 60분간 유의한 차이가 있었다. 이상과 같은 결론을 종합하면 유리지방산의 증가는 스트레스 호르몬 분비와 관계되는 유리지방산의 생성을 유발시키는 역할에 기인하며, 유의한 변화가 나타난 도파민의 결과로 미루어 보아 고강도 탈진운동 집단은 단시간 운동에 의한 스트레스의 강도가 적으므로 회복이 빠르고 중강도 탈진 운동집단은 장시간의 스트레스 노출에 의해 회복이 느린 경향이 나타났다. The purpose of this study was carried to investigate the effects of exhaustive exercise with different on blood free fatty acid, 5-HT and dopamine. The experiments were performed in Sprague-Dawley rats weighing 250-300g. Sixty Sprague-Dawley rats were randomly assigned into two groups: the mild intensity exhaustive exercise group(MIE: n=30), high intensity exhaustive exercise group(HIE: n=30). Animals participating in the exercise protocols were acclimated to treadmill running(20m/min, 15-20 min/day at a 0% grade for 1 week). MIE groups were exercised at 20m/min, 0% grade(50% VO₂max) to physical exhaustion. HIE groups were exercised at 40m/min, 20% grade(80% VO₂max) to physical exhaustion.The results through the statistical analysis of free fatty acid, 5-HT, dopamine in rats were as follow:1. Free fatty acid levels were reduced at post-exercise, but increased at the time of recovery 10mins, 60mins in the mild intensity exhaustive exercise. In the high intensity exhaustive exercise groups were increased according to time. There was significant difference between 10mins after recovery and exhaustion. There was significant difference between groups. 2. Plasma 5-HT levels were significantly higher in the mild intensity exercise groups compared with those in the high intensity exercise groups. 5-HT levels were significant difference between two groups. The mild intensity exercise groups were higher 10mins after recovery than exhaustion and decreased at the time of 60mins recovery. 3. Dopamine levels were elevated at the post-exercise and reduced at the 10mins after recovery in the mild intensity exhausted exercise groups. The high intensity exercise groups were reduced at the exhaustion time and elevated at the time of 10mins recovery. 5-HT levels were no significant difference between two groups, but time of period was significant. There was significant difference between 10mins after recovery and 60mins after recovery.

뇌허혈 후의 트레드밀 운동 시점이 해마 치상회에서 신경세포 사멸과 신경세포 생성에 미치는 영향

정용락,박호윤,임용택,신말순,김성수,송분도,김창주,김상호,하상효 한국코칭능력개발원 2006 코칭능력개발지 Vol.8 No.1

In the present study, we investigated the temporal-dependence of the effect of treadmill exercise on short-term memory, neuronal cell death, and cell proliferation in the hippocampal dentate gyrus following transient global ischemia in gerbils. Transient global ischemia impaired short-term memory function and increased apoptotic neuronal cell death and cell proliferation in the hippocampal dentate gyrus in gerbils. Treadmill exercise for 7 days improved ischemia-induced short-term memory and suppressed ischemia-induced increase in apoptosis and cell proliferation in gerbils. The most potent protective effect of treadmill exercise on ischemia-induced apoptosis was observed when started treadmill exercise at 24 h after ischemic insult. Here, we have shown that treadmill exercise alleviates ischemia-induced short-term memory impairment by suppressing apoptotic neuronal cell death in the hippocampus.

유산소성 운동이 노인들의 신체조성과 등속성 슬관절 근력 및 요부근력에 미치는 영향

한종우(Jong Woo Han),이상석(Sang Sug Lee),송분도(Bun Do Song),지용석(Yong Suk Ji),김난수(Nan Su Kim),서경호(Kyeong Ho Seo) 한국사회체육학회 2000 한국사회체육학회지 Vol.13 No.-

This study was designed to investigate the effect of a year aerobic exercise training on body composition, isokinetic knee and trunk muscular strength of elders. The subjects for this study were eighty healthy elderly people who were members of seniors tower at Song-Do Hospital and didn`t have any history of cardiorepiratory disease. Subjects have been trained three times a week for a year. The exercise program was made up of a 15-minute warm-up, cool-down. Stretching was performed every eight minutes for the prevention of injuries which could occur during the main exercise and quick recovery of the used muscle. Aerobic training was performed for each 15-20minutes using the treadmill and cycle ergometer at the intensity of 50-70% HRmax. For the data, all the measurements were represented by mean and standard deviation using SAS package(version 6.12). Statistical techniques for data analysis were paired t-test to determine the difference between pre and post exercise program. The 5% level of significance was used as the critical level for acceptance of hypotheses for the study. The following results were obtained from this study. 1. There is a statistically significant difference in the VO_2max, fat mass, lean mass and %body fat both old men and women after a year training. 2. There is not a statistically significant difference in the weight, WHR and thigh circumference both old men and women after a year training. 3. There is a statistically significant difference in the right knee flexor/extensor peak torque, peak torque % body weight, total work and total work % body weight both old men and women after a year training. 4. There is a statistically significant difference in the left knee flexor/extensor peak torque, peak torque % body weight, total work and total work % body weight both old men and women after a year training.

Temporal-dependence of the effect of treadmill exercise on ischemia-induced neuronal cell death and cell proliferation in the dentate gyrus of gerbils

Yong-Rak Chung(정용락),Sung-Soo Kim(김성수),Sang-Hyo Ha(하상효),Bun-Do Song(송분도),Ho-Yoon Park(박호윤),Sangho Kim(김상호),Yong-Taek Rhim(임용택),Mal-Soon Shin(신말순),Chang-Ju Kim(김창주) 한국코칭능력개발원 2006 코칭능력개발지 Vol.8 No.1