단일다발 및 이중다발 전방십자인대 재건술의 전향적 무작위적 비교 연구

박상은,임무준,Park, Sang-Eun,Lim, Moo-Joon 대한관절경학회 2010 대한관절경학회지 Vol.14 No.1

목적: 전방십자인대 재건술에 있어서 이중다발과 재건술과 단일다발 재건술의 임상적 결과 및 방사선학적 결과에 대한 전향적 연구를 수행하고자 하였다. 대상 및 방법: 연구는 편측 무릎의 전방십자인대 손상이 있는 56명의 환자군(group T)을 모집하여 27명은 이중다발 재건술군으로 배정하였으며(group D), 29명은 단일다발 재건술군으로 배정하였다(group S). 두 비교군 간의 임상적인 수술 결과는 최소 2년간의 추적 관찰 기간 내 Lysholm knee score, Tegner activity score, Lachman & pivot shift test와 영상 검사(슬관절 전후방 부하 X선 촬영검사)를 통하여 비교 분석하였다. 결과: 술후 2년 추적 관찰에서의 Lysholm knee score, Tegner activity score 수치에서, 두 비교군 사이에 유의한 임상적 차이를 보이지 않았다(p>0.05). Lachman test, pivot shift test와 영상 검사 결과상에서도 두 비교군 사이에 유의한 차이점이 밝혀지지 않았다(p>0.05). 결론: 이중다발 전방십자인대 재건술은 최소 2년간의 추적 관찰에서, 단일다발 재건술에 비해 임상적 결과나, 수술 후 영상 검사 상에서의 우월함을 보이지 못하였다. 이는 전방십자인대 손상 환자들에서 전내측 다발 재건술만으로도 우수한 임상적 결과가 나올 수 있음을 시사한다. Purpose: To evaluate and compare the postoperative knee stability and functional scores between single- and double- bundle anterior cruciate ligament (ACL) reconstruction at a minimum 2 years follow-up. Materials and Methods: 56 patients (group T) with ACL injury in one knee were recruited with 27 allocated to the double bundle ACL reconstruction group (group D) and 29 to the single bundle ACL reconstruction group (group S). Clinical outcomes including Lysholm knee scores, Tegner activity scores, Lachman and pivot shift test results, and radiographic stabilities were also compared between two groups. Results: Clinical outcomes including Lysholm knee and Tegner activity scores were similar in the two groups at 2 years follow-up. Furthermore, stability results of Lachman test, pivot shift test, and radiological findings failed to reveal any significant inter-group differences. Conclusion: Double bundle ACL reconstruction does not produce better in clinical outcomes and postoperative stabilities.

복합성 외측 반월상 연골판 파열에서 슬와건을 한시적 지주로 시행한 구제적 성격의 관절경 봉합술의 임상 결과

박상은,김상길,Park, Sang-Eun,Kim, Sang-Kil 대한관절경학회 2010 대한관절경학회지 Vol.14 No.1

This study was undertaken to document the clinical results and technical aspects of arthroscopic repair including popliteus tendon as a post for the treatment of complex lateral meniscus in young people indicated as total meniscectomy. From June 2004 to May 2006, we prospectively studied arthroscopic repairs on 32 young people knees with symptomatic complex lateral meniscus that was treated by all inside repair technique using Popliteus tendon as a post. Clinical results were evaluated using Lysholm knee scores preoperatively and at final follow-up. 2nd look arthroscopy or MRI was taken at final follow-up. 80% of patients carried out MRI or 2nd look arthroscopy under permission. Most patients who follow up were able to return to their previous life activities with little or no limitation, and no reoperation was required after an average follow-up of 42.8 months. Mean Lysholm knee scores improved from 65.4 (range, 55 to 75) preoperatively to 93.9 (range, 79 to 100) at the final follow-up (P<.001). 80% meniscus healing was found on arthroscopic or MRI follow up. Conclusively, arthroscopic repair using Popliteus tendon as a post is effective for treating young people with complex lateral meniscus tear as a salvage procedure. 이 연구는 반월상 연골판 절제술의 적응증이 되는 복합성 외측 반월상 연골판 파열에서 슬와건을 바탕으로 시행한 구제적 성격의 관절경 봉합술의 임상 결과와 기술적인 방면에 대한 고찰을 위해 시행하였다. 2004년 6월부터 2006년 5월까지 32 사례의 젊고 증상이 있는 복합성 외측 반월상 연골판 파열 환자들을 all inside 방법으로 봉합하였다. 연구는 전향적으로 시행되었으며, 평균 연령은 29.2세(범위, 17~42)이었으며 평균 관찰기간은 42.8개월(범위, 24~50)이었다. 임상 결과는 라이슬럼 스코어(lysholm knee score)와 2차적으로 시행한 관절경 혹은 자기공명영상을 이용하여 평가되었다. 추적관찰은 약 80%에서 시행할 수 있었다. 추적 관찰된 환자들 대부분이 제한 없이 일상생활을 할 수 있었으며 평균 42.8개월의 추적관찰 동안에 재수술을 시행한 경우는 없었다. 평균 라이슬럼 스코어는 수술 전 65.4(범위는 55에서 75)에서 수술후 최종 추적관찰에서 평균 93.9(79에서 100사이)으로 증가되었다(p<.001). 80%에서 관절경으로 혹은 자기공명영상에서 병변의 치유가 확인되었다. 결론적으로 슬와건을 바탕으로 시행한 관절경적 외측 반월상 연골판 봉합술은 복합성 외측 반월상 연골판 파열을 가지고 있는 젊은 환자에서 구제적 성격의 시술로서는 효과적이었다.

국내 M&A 활성화를 위한 방안

박상은,Park, Sang-Eun 벤처기업협회 2003 벤처다이제스트 Vol.30 No.-

뇌졸중환자의 고지혈증에 대한 평진건비탕가감방의 임상적 효과

박상은,홍수현,권오순,서창운,민성순,홍상훈,Park, Sang-Eun,Hong, Su-Hyun,Kwon, O-Sun,Seo, Chang-Woon,Min, Sung-Soon,Hong, Sang-Hoon 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.3

Objectives : This study was aimed at examining significant curative effects of Pyungjingunbitanggagam-bang on CVA(Cerebral Vascular Accident) patients with hyperlipidemia. Methods : The subjects in this study were sixteen patients admitted to Dong-Eui University Oriental Hospital who broke out with CVA from November 2004 through August 2005, with high total cholesterol (240mg/ dl above) or high TG (200mg/dl above). Before prescription. they were tested for total cholesterol, ALT. AST. BUN. and creatinine with fasting and were then prescribed the herbs(Pyungjingnnbitanggagam-bang) for 2 weeks. after which they were retested for total cholesterol. ALT. AST. BUN. and creatinine every 2 weeks. Conclusions : In the whole treatment group, hypertension & DM group. and cerebral infarction group.statistical significance of total cholesterol changes was recognized before and after the treatment.. Pyungjingunbitanggagam-bang decreased total cholesterol in HT. DM. and cerebral infarction groups. In the whole treatment. HT. and DM groups. statistical significance of TG changes was not recognized before and after the treatment. Hepatotoxicity and nephrotoxicity did not appeared when a stroke patient was given Pyungjingunbitanggagam-bang.

국내 M&A의 활성화를 위한 방안

박상은,Park, Sang-Eun 벤처기업협회 2003 벤처다이제스트 Vol.27 No.-

국내 M&A 활성화를 위한 방안

박상은,Park, Sang-Eun 벤처기업협회 2003 벤처다이제스트 Vol.29 No.-

기술거래와 M&A-국내 M&A의 활성화를 위한 방안

박상은,Park, Sang-Eun 벤처기업협회 2003 벤처다이제스트 Vol.26 No.-

국내 M&A의 활성화를 위한 방안

박상은,Park, Sang-Eun 벤처기업협회 2003 벤처다이제스트 Vol.28 No.-

한방적 치료 접근을 통한 Evans 증후군 치험 1례

박상은,최인선,장자원,홍상훈,서상호,Park, Sang-Eun,Choi, In-Sun,Jang, Ja-Won,Hong, Sang-Hoon,Seo, Sang-Ho 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.3

Evans syndrome, as originally described, refers to autoimmune hemolytic anemia accompanied by thrombocytopenia. The autoantibodies in Evans syndrome are directed specifically against red cells, platelets, or neutrophils and are not crossreacting. The incidence of autoimmune hemolytic anemia is estimated to be approximately 10 cases per million people. Many patients have associated disorders, such as lupus erythematosus and other autoimmune disease, chronic lymphadenopathy, or hypogammaglobulinemia. In Oriental Medicine, the approach to Evans syndrome is made in view of deficiency of blood. The ailment was treated through methods of Oriental Medicine. Acupucture and herbal medicine were administered to patients diagnosed with Evans Syndrome by ecchymosis at the lower limb after continued gingival bleeding. As a result significant improvement in RBC, Hb, Hct, and PLT were observed and complaints abated.

뇌졸중환자의 정구성정색소성 빈혈에 대한 사육탕가미방의 임상적 효과

박상은,홍수현,장자원,송수진,홍상훈,서상호,Park, Sang-Eun,Hong, Su-Hyun,Jang, Ja-Won,Song, Su-Jin,Hong, Sang-Hoon,Seo, Sang-Ho 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.4

Objective : Normocytic Normochromic Anemia is one of the most common cases in clinics of all types of morphological Anemia. This study is aimed at examining significant curative effects of Sayuktanggami-bang on Cerebral vascular accident(CVA) patients with Normocytic Normochromic Anemia. Methods : For this study to examine the effects of Sayuktanggami(四六湯加味方), Patients were divided into 2 groups. Group A(experimental group) consisted of 19 cases prescribed Sayuktanggami-bang, Group B (control group) consisted of 15 cases prescribed other herbs. Before presciption, They were tested for CBC, AST, ALT, Total protein, Cholesterol, TG, HDL, BUN, Creatinine, Uric acid, Na, K, Cl while fasting, then were given the herbs over two weeks. They were checked again for changes over those two weeks. Results : In cases of group A, the statistical significance of CBC changes before and after treatment were recognizable : RBC(p<0.01), Hb(p<0.01), Hct(p<0.01). In comparing CBC changes between group A and group B which developed cerebral infarction group, a type of CVA, the significance of curative effects in group A is recognizable over group B before and after treatment : RBC(p<0.01), Hb(p<0.01), Hct(p<0.05). Cytotoxic reaction was nonexistant. Conclusion : Results of this study suggest that Sayuktanggami-bang has curative effects for CVA patients with normocytic normochromic anemia.