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뇌하수체 호르몬의 분비 이상을 보인 Wilson 씨 병
이창기,김석준,김대현,이동욱,이상문,이중기,권범찬,남근하,이한균,박찬규 대한내과학회 1997 대한내과학회지 Vol.52 No.3
Wilson`s disease is a hereditary disorder in hepa- tic excretion of copper that results in toxic accumulations of the metal in liver, brain and other organs. Though there have been some reports of Wilson's disease with hepatic, neurologic, psychiatric symptoms, or hemolytic anemia, a case of Wilson's disease with abnormal secretion of pituitary hormones is, to our best knowledge, the first report in Korea. We report a case of Wilson`s disease with abnormal secretion of pituirary hormones, chronic active hepatitis with feature of early cirrhosis and hemolytic anemia in 18-year-old man showing delayed puberty. And also we describe a case of successful desensitization to penicillamine in a penicillamine hypersensitivity.
김석준,이상문,이중기,백효종,손경락,서화령,남근하,문세광 대한소화기학회 1998 대한소화기학회지 Vol.31 No.2
Autoimmune hepatitis is a chronic necroinflammatory liver disorder of unknown cause associated with circulating autoantibodies and a high serum globulin level. This disease occurs predominantly in young wornen, but rarely in postmenopausal woman. A variety of immunosuppressive agents have been used for the management. However, corticosteroid treatment in postmenopausal woman have a higher cummulative frequency of long-term complications and a lower net henefit-risk ratio than in premenopausal woman. A 69-year-old female was diagnosed to have autoimmune hepatitis in our hospital. We report this case with literature review.
이동욱,이중기,이한균,권범찬,박진석,우창근,남근하,권소정,황중하 대한내과학회 1998 대한내과학회지 Vol.54 No.4
Mesenteric fibromatosis is a rare nonmetastasizing fibrous tumor, characterized by fibroblastic proliferation without evidence of inflammatory response or definite neoplasia. It appears at any age, but mainly in the second to fifth decades as incidence of two to four desmoid tumor cases per 1 million people per annum. It is pseudoencapsulated and locally invasive and has a tendency to recur, but metastases are rare. It is more frequent with Gardner`s syndrome(adenomatosis coli) in which 50% of them will appear as mesenteric fibromatosis. Trauma, especially that of previous surgery, has been associated with the subsequent development of desmoid tumor. The treatment of choice is a wide margin resection of the tumor. we experienced a case of mesenteric fibromatosis without Gardner`s syndrome 2 years after appendectomy in a 31-year old man and recurred at 21 months after resection and report with a review of literatures.