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      • KCI등재

        건강보험 중증질환 급여확대 전후에 따른 진료비 차이에 관한연구

        이정희(Lee, Jung-He),이무식(Lee, Moo-Sik),김지희(Kim, Jee-Hee),문태영(Moon, Tae-Young),김용하(Kim, Yong-Ha),김광환(Kim, Kwang-Hwan) 한국산학기술학회 2010 한국산학기술학회논문지 Vol.11 No.4

        본 연구는 급여 확대 전 2005년 1월 1일부터 6월 30일까지 6개월간과 확대 후 2006년 1월 1일부터 6월 30 일까지 6개월간 총 255명을 조사대상으로 하여 건강보험 중증질환 보험급여 확대에 따른 진료비 증감 요인을 파악 한 결과 다음과 같다. 성별로는 남자 67.8%, 여자 32.2%로 여자보다 남자가 높은 분포를 보였으며, 확대 전·후 또한 여자보다 남자가 높은 분포를 보였다. 투약 및 처치에 따른 진료비 5항목 중에서 방사선료가 530만원대로 가장 많았 고, 시술료 59만원, 기타검사료 20만원 순이었으며, 투약료가 12만원선으로 가장 낮았다. 급여확대 후에 따른 진료비 와의 상관관계를 보면, 투약료는 입원료(p<0.01)와, 주사료는 입원료(p<0.01) 및 투약료(p<0.01)와 시술료는 입원료 (p<0.01), 투약료(p<0.01) 및 주사료(p<0.01)와 정상관관계를 보였다. According to a research analysis of the factors which affect the medical utilization fee after an increase of health insurance benefits for patients with serious illnesses based on 225 patients over 6 months, both before and after the increase of benefits, from January, 1st, 2005 to June 30th, and also from January, 1st, 2006 to June 30th. In terms of genders, 67.8% of males were affected, whereas only 32.2% of females were effected, a much higher rate of men than women. Men also had higher rates before and after the increase of benefits. Out of 5 categories related to medication and treatment, radiation testing was the most expensive at about 5,300,000, operation fees were 590,000, and costs of other testing approximately 200,000 with the least expensive category being 120,000 for medication. By looking at the relationship between the fees and increase of benefits, medication was a hospital charge (p<0.01), injection fees were hospital charges (p<0.01), operation fees were hospital charges (p<0.01). Medication fees (p<0.01) and injection fees (p<0.01) were found to be related.

      • SCIESCOPUSKCI등재

        비유전독성 간발암물질인 Cloibrate 의 F344 랫드에 있어서 경구 아급성독성시험

        정자영(Ja Young Jeong),이국영(Kook Kyung Lee),신동환(Dong Hwan Shin),한범석(Beom Seok Han),김대중(Dae Joong Kim),강태석(Tae Seok Kang),김기상(Ki Sang Kim),장동덕(Dong Deuk Jang),김창옥(Chang Ok Kim),김효정(Hyo Jung Kim),김지희(Jee He 한국응용약물학회 1995 Biomolecules & Therapeutics(구 응용약물학회지) Vol.3 No.1

        Clofibrate, a peroxisome proliferator, is hepatocarcinogenic in rats in a dose-dependent manner. A total of 70 male and female F344 rats, 5-week-old, were divided into three groups. Rats were fed clofibrate at 0, 0.25, or 0.5% in diet for 30 days. All rats were anesthetized with CO₂, blood samples were taken by cardiac puncture for hematology and clinical chemistry, and the rats were killed by exsanguination. Livers, kidenys, pancreas, adrenal glands, spleen, heart, lungs, thyroid gland, reproductive organs, and digestive organs were removed, weighed, later processed, and embedded with paraplast for histological examination. The relative liver and kidney weights with respect to final body weight in the clofibrate-treated group were significantly increased compared with those of control group at all dose levels (p<0.01). It has been suggested that clofibrate may influence on hepatotoxicity by increases in peroxisomal proliferation.

      • 성인에서 발병한 지역사회폐렴의 원인으로서 호흡기 바이러스의 역할

        김지희,곽영호,나병국,이주연,신구철,정혜선,홍정연,오명돈,정희진,김민자,배현주,김양리,신완식,강재명,우준희,어수택,이환종 대한감염학회 2001 감염 Vol.33 No.1

        Purposes : To investigate the viral etiology of community-acquired pneumonia in Korean adults, we have detected respiratory viruses (Respiatory syncytial virus, adenovirus, influenza virus and parainfluenza virus) in the way of prospective, multi-center study. Methods : From July 1997 to April 2000, nasal aspirates or sputum were obtained from adults patients with community pneumonia admitted to the participating hospitals and transferred immediately to the central laboratory at the Seoul National University Children's Hospital. The specimens were divided into three parts. One part was used for indirect immunofluorescent test for respiratory viruses, the other part for the culture of RSV and adenovirus in HEp-2 cell monolayer. The other part was used for the culture of influenza virus and parainfluenza virus in MDCK or LLC-MK2 cell monolayers. Results : Of 317 samples, 32 (10.1%) specimens were positive for viral agent by indirect IF staining or culture, including one dual-infected specimen (adenovirus and parainfluenza virus). Influenza virus was most commonly detected (16 specimens). Parainfluenza virus, adenovirus and RSV were detected in 10, 4 and 3 patients, respectively. All isolated influenza viruses were type A (H3N2 in 9 patients, HIN1 in 2 and unspecified in 5), and 8 out of 10 parainfluenza virus isolates were type 3. Conclusion : Similar to previous reports from other countries, a significant portion of community-acquired pneumonia in Korean adult is caused by respiratory viruses. (Korean J Infect Dis 33:8~14, 2001)

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