육미지황환(六味地黃丸)의 제방원칙(制方原則)및 배합원리(配合原理)에 관(關)한 연구(硏究)

김윤현 ( Yoon Hyeon Kim ),윤창열 ( Chang Yeol Yoon ) 대한한의학원전학회(구 대한원전의사학회) 2010 대한한의학원전학회지 Vol.23 No.6

The conclusions after studying the rules and the principles of the six-drugs mixing forming the prescription of Yukmijihwanghuan(六味地黃丸) are as follows: 1. Yukmijihwanghuan cares for the three viscera; the liver, the spleen and the kidney and the three entrails; the urinary bladder, the gall bladder, and the stomach and it strengthens them as well. The drug can be used mainly for the cure of the Three Yang Channels of Foot and the Three Yin Channels of Foot. 2. The three drugs of Yukmijihwanghuan; Rehmanniae Radix, Dioscoreae Rhizoma, Corni Fructus altogether has the tonifying effect and the other three; Alismatis Rhizoma, Moutan Cortex, Poria has the purging effect. The first three kinds of drugs tonifies and the last three kinds of drugs purges. While these two groups of drugs are pitted against each other, they also balance each other harmoniously increasing the curative effect(remedial[curative] value). 3. Yukmijihwanghuan cools off the lung which is under metal category, helps the spleen, an earth category to be strong. It also adds the Water Qi to the kidney so that it stabilizes the Fire Qi. 4. Yukmijihwanghuan helps the kidney strongly, helps the urine to be excreted well, cools down the Fire Qi and makes dry things wet. 5. Rehmanniae Radix, the principal drug of Yukmijihwanghuan and Corni Fructus, the minister drug of the medicine have a taste of thick and are materially heavy. The two drugs do the descending action that it tonifies Yin Qi and adds Essence of Life. The other ingredients of Yukmijihwanghuan; Moutan Cortex, Poria, Alismatis Rhizoma have effects on lowering the Fire Qi. If Fire Qi descends, then Water Qi ascends. Yukmijihwanghuan has an efficacy of lowering Fire Qi and increasing Water Qi.

MatlabSimulink를 이용한 2기 계통 모델링

이상성(Sang-Seung Lee),반우현(Yu-Hyeon Ban),석광호(Kwang-Ho Seok),김윤상(Yoon Sang Kim),오용택(Yong-Taek Oh),박철원(Chul-Won Park) 대한전기학회 2012 대한전기학회 학술대회 논문집 Vol.2012 No.5

본 논문에서는 대형 발전기 사고 모의를 위한 Matlab/Simulink 툴을 사용하여 2기 모델링을 한 다음 이를 모의하였다. 사고 모의는 Matlab/Simulink 요소들을 사용하여 ABC상중 A상에 지락 고장을 발생시켰다. 결과 파형들은 발전기 #1 및 #2에 대하여 A상전류, A상 선로측 전압 파형을 비교 검토하였다.

슬관절 이하 만성폐색성 동맥질환의 경피경관 혈관성형술

윤웅,김재규,박수민,김윤현,강형근,Yoon, Woong,Kim, Jae-Kyu,Park, Soo-Min,Kim, Yun-Hyeon,Kang, Heoung-Keun 대한영상의학회 1996 대한영상의학회지 Vol.34 No.2

Purpose : The purpose of this study was to determine the safety and efficacy of the percutaneous transluminalangioplasty(PTA) in patients with chronic arterial occlusive disease below the knee joint. Materials and Methods :We retrospectively analyzed the results of 36 procedures in 16 patients. There were 15 men and one woman, aged57-75 years(mean, 62 years). Indications were disabling claudication(SVS/ISCVS grade 1, category 3) in five cases,rest pain(grade 2, category 4) in three cases, and non-healing ulceration or gangrene(grade 3, category 5) ineight cases. PTA was performed by using small vessel balloon catheter of 2-4 mm and 3 mm monorail balloon catheterin tibioperoneal vessels and 5-6 mm balloon catheter in distal popliteal artery and tibioperoneal trunk. Combinedthrombolytic therapy with Urokinase was performed in 14 patients. Results : Involved infrapopliteal vessels werefour distal popliteal arteries, 15 tibioperoneal trunks, six anterior tibial arteries, five posterior tibialarteries, and seven peroneal arteries. Technical success was determined when post-PTA angiogram showed less than30% of residual stenosis. Clinical success was defined as improvement of clinical symptoms, such as disappearanceof claudication or rest pain, and healing of ulceration. Technical success was achieved in 30 of 36 arteries(83%).Clinical success was achieved in 12 of 16 patients(75%) at an average follow-up of 13.3 months(range, 2-46months). Clinical success rate was 100% in grade 1 category 3 patients, 67% in grade 2 category 4 patients, and63% in grade 3 category 5 patients. Complication included two distal emboli, one vessel rupture, one vesselthrombosis, and one occluding intimal flap. Conclusion : PTA was an effective method for treatment of chronicarterial occlusive disease below the knee joint and considered as the procedure of first choice. Severeclaudicant(grade 1) should be included in the indication of the tibioperoneal PTA.

조력발전플랜트를 위한 발전기 제어시스템의 개관

박철원(Park Chul-Won),반우현(Ban Woo-Hyeon),안상지(Ahn Sang-Ji),김윤상(Kim Yoon-Sang) 대한전기학회 2012 대한전기학회 학술대회 논문집 Vol.2012 No.5

가토의 급성 뇌경색에서 관류 및 확산강조 자기공명영상

허숙희,임남열,정광우,윤웅,김윤현,정용연,정태웅,김정,박진균,강형근,서정진,Heo Suk-Hee,Yim Nam-Yeol,Jeong Gwang-Woo,Yoon Woong,Kim Yun-Hyeon,Jeong Young-Yeon,Chung Tae-Woong,Kim Jeong,Park Jin-Gyoon,Kang Heoung-Keun,Seo Jeong-Jin 대한자기공명의과학회 2003 Investigative Magnetic Resonance Imaging Vol.7 No.2

목적 : 가토 모델을 이용한 급성 허혈성 뇌경색에서 확산강조 자기공명영상과 관류자기공명영상의 유용성에 대해 알아보고자 하였다. 대상 및 방법 : 여섯 마리의 순계 가토의 경동맥에 히스토아크릴글루와 리피오돌 및 텅스텐 파우더를 동맥내 주입하여 뇌경색을 유발한 후 1시간 내에 고식적인 T1 및 T2 강조영상, 그리고 확산강조 자기공명영상과 관류자기공명영상을 획득하였다. 관류자기공명영상은 측내실 수준과 대뇌기저핵의 1cm 상방에서 각각 얻었고, 이 영상을 특수 영상 소프트웨어로 후처리하여 뇌혈류 용적 , 뇌혈류양 및 평균 조영제 통과시간을 포함한 관류 영상을 획득하였다. 뇌경색 부위는 각각의 관류 지도와 확산강조 자기공명영상으로 평가하였다. 뇌경색 부위와 반대편 정상 부위에서 조영제 평균 통과시간 차이를 측정하였다. 결과 : 모든 가토에서 T2 강조영상상 비정상 신호강도는 없었으나 확산강조 자기공명영상에서 고신호강도의 뇌경색 병변을 확인할 수 있었다. 상대적 뇌혈류용적, 뇌혈류양 및 평균 조영제 통과시간을 포함한 관류자기공명영상에서 모두 관류 결손을 인지할 수 있었다. 뇌혈류양과 평균 조영제 통과시간 지도에서 관류결손지역으로 나타난 면적의 비교는 6예 중 4예에서 평균 조영제 통과시간 지도가 뇌혈류양 지도보다 면적이 크게 나왔으며, 2예는 같았다. 평균 조영제 통과시간 지도의 관류결손 면적이 뇌혈류양 지도보다 작게 나온 경우는 없었다. 또한 뇌혈류양 지도에서 병변의 면적은 확산강조 자기공명영상에서의 병변의 면적보다 3예에서 넓게 나타났고, 3예에서 같게 나타났다. 평균 조영제 통과시간 지도에서 병변의 면적은 확산강조 자기공명영상에서의 병변의 면적보다 모두 크게 나타났다. 평균 조영제 통과시간 지도에서 병변의 면적이 뇌혈류양 지도에서 병변의 면적보다 크면서 확산강조 자기공명영상에서와 같은 경우가 3예, 뇌혈류양 지도에서 병변의 면적이 확산강조 자기공명영상에서와 같으며 평균 조영제 통과시간 지도에서 병변의 면적보다 작은 경우가 3예, 그리고 평균 조영제 통과시간 지도에서 병변의 면적이 뇌혈류양 지도의 병변의 면적보다 크면서 확산강조 자기공명영상에서의 면적이 가장 적은 경우가 1예 있었다. 결론 : 확산강조 자기공명영상과 관류자기공명영상은 가토에서 초급성 뇌경색을 진단하고 뇌혈류 역학상태를 평가하는데 유용한 기법이라고 생각된다. Purpose : The present study was undertaken to evaluate the usefulness of cerebral diffusion (DWI) and perfusion MR imaging (PWI) in rabbit models with hyperacute cerebral ischemic infarction. Materials and Methods : Experimental cerebral infarction were induced by direct injection of mixture of Histoacryl glue, lipiodol, and tungsten powder into the internal cerebral artery of 6 New-Zealand white rabbits, and they underwent conventional T1 and T2 weighted MR imaging, DWI, and PWI within 1 hour after the occlusion of internal cerebral artery. The PWI scan for each rabbit was obtained at the level of lateral ventricle and 1cm cranial to the basal ganglia. By postprocessing using special imaging software, perfusion images including cerebral blood volume (CBV), cerebral blood flow (CBF), and mean transit time (MTT) maps were obtained. The detection of infarcted lesion were evaluated on both perfusion maps and DWI. MTT difference time were measured in the perfusion defect lesion and symmetric contralateral normal cerebral hemisphere. Results : In all rabbits, there was no abnormal signal intensity on T2WI. But on DWI, abnormal high signal intensity, suggesting cerebral infarction, were detected in all rabbits. PWI (rCBV, CBF and MTT map) also showed perfusion defect in all rabbits. In four rabbits, the calculated square of perfusion defect in MTT map is larger than that of CBF map and in two rabbits, the calculated size of perfusion defect in MTT map and CBF map is same. Any rabbits do not show larger perfusion defect on CBF map than MTT map. In comparison between CBF map and DWI, 3 rabbits show larger square of lesion on CBF map than on DWI. The others shows same square of lesion on both technique. The size of lesion shown in 6 MTT map were larger than DWI. In three cases, the size of lesion shown in CBF map is equal to DWI. But these were smaller than MTT map. The calculated square of lesion in CBF map, equal to that of DWI and smaller than MTT map was three. And in one case, the calculated square of perfusion defect in MTT map was largest, and that of DWI was smallest. Conclusion : DWI and PWI may be useful in diagnosing hyperacute cerebral ischemic infarction and in e-valuating the cerebral hemodynamics in the rabbits.