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김용진,김형건,김형주,박진철,Kim, Yong-Jin,Kim, Hyung-Kun,Kim, Hyung-Ju,Park, Jin-Chul 대한미세수술학회 1998 Archives of reconstructive microsurgery Vol.7 No.1
We carried out 107 replantations of amputated digits since last 1988. Among them, clean Gillotine amputation was 19 digits, mild crush amputation was 51 digits, severe crush amputation was 28 digits and avulsion type amputation was 9 digits. Vein grafts were used on 24 of these cases. The donor site of the vein graft was the volar aspect of the ipsilateral wrist or lower forearm. The average length of the vein graft was 1.8cm(1.0-3.0cm) and the average diameter of the vein graft was 1.5mm(1.0-2.0mm). Sixty-one of 107 digits were successfully replanted for an 57% success rate. The survival rate of the replantation using the vein graft was 66.7%. We analysed the functional results of the successfully replanted digits according to Nakamura and Tamai's criteria. The functional results of the replantated digits using vein graft were better than that of without using vein graft(more than fair results, 81.2% vs 73.3%). We conclude that the jucidious use of autogenous vein grafts in digital replantation surgery will improve the survival rate and promote the functional result.
김용진,박우전,조삼현,Kim, Yong-Jin,Park, U-Jeon,Jo, Sam-Hyeon 한국전자통신연구원 1987 전자통신 Vol.9 No.1
본고에서는 소프트웨어의 생산성 향상을 위해서 좋은 프로그래밍 환경은 필수적이며 이중 모범이 되는 Ada 프로그래밍 환경을 소개한다.
제5판 UICC TNM림프절 분류에 따른 pT3pN1 위암 환자에서 림프절의 해부학적인 위치에 따른 2군 림프절 양성의 의의
김용진,김병식,최원용,육정환,오성태,박건춘,Kim Yong Jin,Kim Byung Sik,Choi Won Yong,Yook Jung Hwan,Oh Sung Tae,Park Kun Choon 대한위암학회 2004 대한위암학회지 Vol.4 No.1
Purpose: The most important prognostic factors in gastric cancer is the depth of invasion of the primary tumor and lymph node metastasis. The nodal staging of the 5th edition of the Union Internationale Contrala Cancrums (UICC) TNM classification in 1997 was changed based on the number of metastatic lymph node. We attempted to evaluate the prognostic significance of N2 group metastasis in pT3pN1 gastric cancer patients by comparing two different nodal staging systems. Materials and Methods: A retrospective analysis was made for 352 gastric cancer patients who underwent curative resection, including D2 dissection, from 1991 to 1997 at Asan Medical Center. A clinicopathologic comparison between two groups by using a nodal staging systems was summarized into a table. Cumulative survival rates were calculated by using the Kaplan-Meier method. The difference between the two groups was evaluated by using the log rank test with SPSS 11.5 for Windows Results: There were no statistical differences in clinicopathologic factors. However, there was a significant difference in survival rate between the two groups (P=0.0009). This suggests that N2 group metastasis in pT3pN1 gastric cancer patients has a clinical significance for predicting prognosis. Conclusion: Our results suggest a possibility of prognostic significance of N2 group metastasis. Therefore, anatomical location of the lymph node should be described.
장막침윤이 없는 위암환자에서 수술 후 보조적 화학 요법에 대한 전향적 연구 -최종보고-
김용진,김병식,김용호,육정환,오성태,박건춘,Kim Yong Jin,Kim Byung Sik,Kim Yong Ho,Yook Jung Hwan,Oh Sung Tae,Park Kun Choon 대한위암학회 2004 대한위암학회지 Vol.4 No.4
목적: 장막침윤이 없는 위암환자에 있어서 수술 후 서로 다른 보조화학요법이 장기 생존에 미치는 영향에 대해 평가하고자 하였다. 대상 및 방법: 1996년 10월부터 1998년 3월까지 만 15개월간 서울 아산병원 외과에서 근치적 위 절제를 시행한 환자 중, 장막침윤이 없는 317명의 환자를 대상으로 하였다. 이중 수술 후 병기가 IA인 131예, 장막침윤이 있는 34예, 그리고 치료를 거부한 17예를 제외한 135명(1군: 5-FU+cisplatin 정주, 2군: mitomycin C정주+경구용5-FU, 3군: 경구용 5-FU)의 의무기록 분석과 전화추적을 실시하여 재발양상, 생존율, 및 위암관련 사망률을 각 군별로 분석하였다. 결과: 121명에서 추적이 가능해 $89.6\%$의 생존율을 나타냈다. 재발은 1군 4명, 2군 7명, 그리고 3군 6명 이었으며, 세 군의 전체생존율은 1군 $89\%$, 2군 $84\%$, 그리고 3군은 $82\%$이고, 위암관련 사망환자만을 고려한 질병특이 생존율은 1군 $92\%$, 2군 $86\%$, 그리고 3군은 $88\%$로 나타나 이들 세 군간에 전체생존율 및 질병특이 생존율은 차이를 보이지 않았다(전체생존율: P=0.6875, 질병특이 생존율: P=0.7120). 결론: 장막침윤이 없는 위암 환자에서, 치료효과를 향상 시키기 위해 보조요법을 시행할 경우 경구용 항암제를 이용한 방법이면 충분하다고 판단하였다. 그러나 이를 입증하기 위해서는 보조요법을 시행치 않는 대조군을 포함한 대단위 무작위 연구가 필수적일 것이다. Purpose: We reported our preliminary result in 2001. At that time, the follow-up period was too short to evaluate the survival benefit of adjuvant chemotherapy in gastric cancer without serosal invasion. Therefore, we followed those patients for 66 months to determine the long-term effects of adjuvant chemotherapy. Materials and Methods: We analyzed the recurrence pattern, the survival rate, and the disease-specific survival of 135 patients by reviewing their medical records and calling the patients or their relatives. All enrolled patients were included in the intention-to-treat analysis of efficacy. Results: The follow-up rate was $89.6\%$ (121/135), and the median follow-up duration was 66 months. Among the 135 patients, 4 relapsed in group 1 (5-FU+cisplatin), 7 in group 2 (mitomycin C+oral 5-FU), and 6 in group 3 (oral 5-FU only). The overall survival rate was $89\%$ in group 1, $84\%$ in group 2, and $82\%$ in group 3. There were no differences in the overall survival rates and the disease-specific survival rates among the three groups. Conclusion: Oral chemotherapeutic agents have an acceptable effect for adjuvant chemotherapy compared with intravenous agent. However, a large-scale, prospective, randomized study, including a control group, is needed for an exact evaluation.
Anisakis病에 의한 호산구성 ( 好酸球性 ) 장염 ( 場炎 )
김용진(Yong Jin Kim),정진영(Jin Young Jung),김원근(Won Kun Kim),송준화(Jun Hwa Song),김교선(Kyo Sun Kim),김중구(Joong Gu Kim),박하철(Ha Chul Park),이종찬(Jong Chan Lee) 대한소화기학회 1990 대한소화기학회지 Vol.22 No.2
Eosinophilic enteritis is characterized by marked submucosal edema and massive infiltration of eosinophiles throughout the entire intestinal wall. The etiology of this disease is not clear until now, although some authors insisted that some gastrointestinal allepens, parasites or collagen diseases. Authors report the case of eosinophilic enteritis of ileum with embedded larva of Anisakis, which is thought as etiology. The patient is 47-year-old male, who was healthy, received operation due to acute abdominal pain with small bowel obstruction. He lived in Eastern sea side of Korea and liked to eat the raw cuttle fish. The specimen is segmental resected product of ileum and shows central small ulcer lesion and marked submucosal edema. On histiology examination, marked eosinophilice infiltration throughout the mucosa to serosal layer, accompanied with marked submucosal edema. The three segmented body of Anisakis larva is present in mucosa to submucosal area, which site is just correlated with small ulcer lesion on gross examination. We concluded that the possibility of Anisakiasis as etiology of eosinophilic enteritis may be high especially in the cases of sea-side inhabitants. So we think that careful seria1 sections for pathologic examination is needed in such cases.
퇴적층 배양에 따른 식물플랑크톤 군집 형성과 이취미물질 발생 특성
김용진 ( Yong Jin Kim ),윤석제 ( Seok Jea Youn ),김헌년 ( Hun Nyun Kim ),박응로 ( Eung Roh P가 ),황문영 ( Moon Young Hwang ),박진락 ( Jin Rak Park ),이병천 ( Byoung Cheun Lee ),이재관 ( Jae Kwan Lee ) 한국물환경학회 2014 한국물환경학회지 Vol.30 No.6
In this study, Uiam-sediment(US) and Gongji-sediment(GS) were incubated to analyze the formation of phytoplankton community and occurrences of odorous compounds from benthic cyanobacteria. For the phytoplankton, 45 and 40 taxa were found in GS and US, respectively. The phytoplankton species detected in the harmful algae included Microcystis, Anabaena and Oscillatoria. As a result, a standing crop of phytoplankton appeared to be in the range of 0.9∼71.8×103 cells/mL in GS, 0.8∼51.2×103 cells/mL in US, and as the incubation progressed, benthic cyanobacteria was increased. The highest number of akinetes was shown in the initial incubation, and akinetes was reduced by 10% on day 4 of incubation start. After reduction of akinetes incubated for 4 days in US and 15 days in GS, Anabaena appeared from the surface water. Benthic cyanobacteria such as Oscillatoria tenuis, O. limosa and Lyngbya hieronymusii was dominant in GS(max. 3.96×106 cells/cm2) and US(max. 5.77×106 cells/cm2), forming cyanobacterial mats in sediment surface. Cyanobacterial mats were suspended after 10∼12 days incubation in GS and US. Before and after the suspension of cyanobacterial mats, the concentration of geosmin was the highest in GS(115 ng/L) and US(175 ng/L). In the second suspension of cyanobacterial mats in GS, the concentration of 2-MIB was increased to the range of 22~92 ng/L.
증례 : 항암 화학 요법 및 방사선 요법으로 장기 생존을 보인 상악동에 생긴 골육종 1예
김용진 ( Yong Jin Kim ),김진영 ( Jin Young Kim ),성희진 ( Hee Jin Seong ),박우영 ( Woo Young Park ),권선영 ( Sun Young Kwon ),도영록 ( Young Rok Do ),송홍석 ( Hong Suk Song ) 대한내과학회 2007 대한내과학회지 Vol.72 No.4
저자들은 광범위 수술적 절제가 불가능한 상악동 부위에 생긴 골육종 환자에 대해 항암화학요법과 방사선 요법을 시행하여 장기 생존을 보인 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Maxillary osteosarcoma is an aggressive disease with a high mortality rate. Extensive surgical resection is accepted as the standard treatment for the disease. The beneficial role of chemotherapy and radiotherapy in the treatment of the disorders is uncertain. We experienced a case of an osteosarcoma of the maxillary sinus. Paranasal sinus computed tomography showed a huge solid mass lesion at the left maxillary sinus walls. An endoscopic biopsy showed an osteoblastic type osteosarcoma. In this case, radical surgery was impossible, and the patient was treated with chemotherapy and radiotherapy. This regimen involved four cycles of chemotherapy, cisplatin, 100 mg/m2 intravenously on the first day of weeks 1, 4, 7, and 10, and doxorubicin, 25 mg/m2 per day on the first 3 days of weeks 1, 4. 7. and 10, followed by external beam radiotherapy with a total dose of 6,600 cGy. We report here a case of an inoperable osteosarcoma of the maxilla with long-term survival after chemotherapy and radiotherapy with an accompanying review of the literature. (Korean J Med 72:437-440, 2007)
김용진(Yong Jin Kim),박성환(Sung Hwan Park),주대현(Dae Hyun Joo),이한일(Han Il Lee),유용운(Young Oon Yoo),박기호(Ki Ho Park),이진우(Jin Woo Lee),김양일(Yang Il Kim) 대한소화기학회 1997 대한소화기학회지 Vol.29 No.2
The authors experienced a case of diffuse gastric polyposis with focal malignant transformation. A 61-year-old male visited this hospital because of epigastric pain. The gastrofibroscopic examination showed numerous polyps in entero-gastric mucosa mainly in the antrum and confirmed malignant change from one of the largest polyps in the antrum in the preious gastrofibroscopic examination dane six years ago. There was no family history of gastrointestinal polyps and the colon of this patient was intact. The total numbers of polyps was numerous, about 300, or more in the gastrectomized specimen. The size of polyps are variable, from less than 1mm to over 10mm, the largest one being 1,2cm * 0.5cm, but most of them were less than 0.3cm. The polyps were seattered in the fundus, cardia, body and antral portion of the stomach, but located mainly in the antrum, about 80% or more. All of the polyps were sessile. Microscopically, focal dysplastic changes and rnalignant changes were found in the superficial layer of the mucosa, which were located in the antrum. The remsining mucosa showed chronic atrophic gastritis associated with intestinal metaplasia, The hyperplastic gastric polyps comprised of appoximatcly 75% of all gastric epitheiial polyps. A coincident gastric carcinoma was repotted in 1.7%-2% patients with hyperplsatic polyps, Carcinoma lesions could be classified as type IIa early gastric cancer. At operation, there were no enlarged regional lymph nodes, and the other intraaMominal organs were intact grossly. There were no metastatic tumors in 35 dissected regional lymph nodes. The D2, total gastrectamy, Roux-En-Y, was performed, and the patient recovered uneventually (Korean J Gastroenterol 1997; 29:274 - 278)