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      • KCI등재

        Spark plasma sintering을 이용한 수분무 Al-Zn-Mg합금분말의 소결특성

        김선미,김택수,김영도,김정곤,Kim, Sun-Mi,Kim, Taek-Soo,Kim, Young-Do,Kim, Jeong-Gon 한국분말야금학회 2009 한국분말재료학회지 (KPMI) Vol.16 No.1

        In order to investigate the effect of rapid solidification on the microstructure and the mechanical properties of Al-Zn-Mg system alloys, water atomization was carried out, since the water atomization beared the highest solidification rate among the atomization processes. The as atomized alloy powders consisted of fine grains less than 4 ${\mu}m$ in diameter, and the second particles were not detected on XRD. The microstructure as solidified was maintained even after the spark plasma sintering at the heating rate of 50 K/min. On the other hand, lower rate of 20 K/min induced a formation of $MgZn_2$ particles, resulting in strengthening of the matrix. The density was almost constant at the temperature above 698K. The sintering temperature above 698K had no effect on the strength of the sintered materials.

      • KCI등재

        중소기업 근로자의 일·생활 균형을 위한 가족친화경영 우수사례연구

        김선미,구혜령,강복정,Kim, Seon Mi,Koo, Hye Ryoung,Kang, Bog Jeong 한국가족자원경영학회 2020 가족자원경영과 정책 Vol.24 No.2

        This qualitative case study focuses on five small and medium-sized enterprises which have put family-friendly management into successful practice. Through in-depth unstructured interviews with five human resources managers and ten employees, we describe each firm's approach to work-life balance including working hour reductions, breaks, work flexibility, and parental leave to build an overall picture. We also discuss the four key factors of the CEO's role; democratic communication between all staff, the usefulness of family-friendly certification as a starting point; and governmental support for promoting work-life balance at small and medium-sized enterprises. Finally, we suggest three political implications of governmental support, namely CEO education, changing the criteria of family-friendly certification to redefine working hours and work flexibility, and incentives specifically for small to medium-sized enterprises.

      • KCI등재

        Biological Activity of Tumor Necrosis Factor-α Secreted from Smooth Muscle Cell Overexpressing FADD

        김선미,이경아,김관회,Kim, Sun-Mi,Lee, Kyeong-Ah,Kim, Koan-Hoi Korean Society of Life Science 2007 생명과학회지 Vol.17 No.1

        세포 배양액에 tetracycline이 없는 경우 FADD를 발현하면서 사멸하는 평활근세포 (FADD-SMC)에서 분비하는 $TNF-\alpha$의 활성을 조사하였다. 배양액에 tetracycline이 없는 경우 FADD-SMC는 약 1000 pg/ml의 $TNF-\alpha$를 분비하였다. $TNF-\alpha$를 포함하는 배양액을 분리하고, 이 배양액을 정상세포에 처리한 결과 인산화한 p38 MAPK와 nuclear, factor, kappa B (NF-kB)의 활성이 증가하였다. 또한 이 배양액을 L929 세포에 처리하는 경우 세포독성이 발생하였다. NF-kB, p38 MAPK 그리고 L929 세포에 대찬 효과는 배양액에서 suluble TNF receptor를 이용하여 $TNF-\alpha$를 제거하는 경우 감소하였다. This study investigated biological activity of tumor necrosis factor $(TNF)-\alpha$ secreted from smooth muscle cell (SMC) destined for death by expressing Fas associated death domain containing protein (FADD) (FADD-SMC) when the cells are grown without tetracycline in culture medium. In the absence of tetracycline the FADD-SMC secreted approximately 1000 pg/ml $TNF-\alpha$, whereas hardly detectable amount of the cytokine existed in the presence of tetracycline. The culture medium collected from the FADD-SMC grown in the absence of tetracycline increased phosphorylated form of p38 MAPK and up-regulated nuclear factor kappa B (NF-kB). The medium collected without tetracycline also caused death of L929 cells. Depletion of $TNF-\alpha$ with the soluble TNF receptor (sTNFR) inhibited the phosphorylation of p38 MAPK, the up-regulation of NF-kB activity and the death activity of the medium collected from FADD-SMC in the absence of tetracycline. These results indicate that $TNF-\alpha$ secreted from SMC undergoing death is biologically active and can affect cellular function.

      • 외래어 발음에서 나타난 영어와 한국어의 운율적 차이

        김선미,문수미,Kim Sunmi,Moon Soo-Mee 대한음성학회 1998 말소리 Vol.35 No.-

        The prosodic properties of Korean and English stress were examined with focus on syllable duration and pitch by loan words. 14 loan words were selected by the criteria of the numbers of syllables and stress positions. 3 Korean males using Seoul dialect and 3 American males using general American English served as subjects. Each tokens were uttered 3 times and second one was chosen to be analysed by CSL. We measured the duration and F0 of each syllable. In English, duration is the most salient acoustic correlates of stress, and pitch is the second. In Korean, by contrast, it seems that neither duration nor pitch is the acoustic features of stress, from our data

      • KCI등재

        유방의 노카르디아증: 증례 보고

        김선미,박정미,Kim, Seon-Mi,Park, Jeong-Mi 대한영상의학회 2003 대한영상의학회지 Vol.49 No.5

        노카르디아증은 주로 면역결핍환자에서 기회감염으로 발생하는 질환으로 유방에 발생하는 경우는 전세계적으로 4예정도가 보고되어 있으며,국내에서는 발표된 바 없다.저자들은 쿠싱씨 병환자에서폐감염과 동반된노카르디아에 의한 유방 농양1예를 경험하였기에그 방사선학적소견을 보고한다.병변은 유방촬영상 유방에 경계가 좋은 관상 음영이 수개 모여 있었으며 초음파 상으로는 유선과 피하지방내에 경계가 불명확하고 불규칙한 모양의 병변으로 보였고,내부에 높은 에코를보이는움직이는찌꺼기들이있었다.m Nocardiosis is an opportunistic infection occurring in immunocompromised patients. Worldwidely, about four cases of nocardiosis of the breast have been previously reported, but none of these were in Korea. We describe a case of breast nocardiosis associated with pulmonary infection in a patient with Cushing's disease. In our patient, multiple, well-defined, conglomerated, tubular-shaped, isodense mass was revealed at mammography, and an irregular-shaped, ill-defined, heterogeneous echoic mass with movable debris at ultrasonography

      • KCI등재

        Characterization of Antibiotic Resistance Determinants in Oral Biofilms

        김선미,Hyeong C. Kim,이석우 한국미생물학회 2011 The journal of microbiology Vol.49 No.4

        Oral biofilms contain numerous antibiotic resistance determinants that can be transferred within or outside of the oral cavity. The aim of this study was to evaluate the prevalence and the relative level of antibiotic resistance determinants from oral biofilms. Oral biofilm samples that were collected from healthy subjects and periodontitis patients were subjected to qualitative and quantitative analyses for selected antibiotic resistance determinants using PCR. The prevalence of tet(Q), tet(M), cfxA, and blaTEM was very high both in the patient and the healthy subject group, with a tendency toward higher values in the patient group,with the exception of erm(F), which was more prevalent in the healthy group. The two extended spectrum β-lactam (ESBL) resistance determinants blaSHV and blaTEM showed a dramatic difference, as blaTEM was present in all of the samples and blaSHV was not found at all. The aacA-aphD, vanA, and mecA genes were rarely detected, suggesting that they are not common in oral bacteria. A quantitative PCR analysis showed that the relative amount of resistance determinants present in oral biofilms of the patient group was much greater than that of the healthy group, exhibiting 17-, 13-, 145-, and 3-fold increases for tet(Q), tet(M),erm(F), and cfxA, respectively. The results of this study suggest that the oral antibiotic resistome is more diverse and abundant in periodontitis patients than in healthy subjects, suggesting that there is a difference in the diversity and distribution of antibiotic resistance in oral biofilms associated with health and disease.

      • KCI등재

        맞벌이 부부의 가사노동에 관한 질적 연구 - 초등학생 자녀를 둔 맞벌이 부부를 중심으로

        김선미,장상옥,Kim, Seon-Mi,Jang, Sang-Ock 한국가족자원경영학회 2005 가족자원경영과 정책 Vol.9 No.3

        The purpose of this study is to identify the characteristics of the household labors that are performed by dual income families. The methodology that has been applied in this study was a qualitative research based on in-depth interviews of a total of 10 people(8 housewives, 2 husbands) selected from the 8 different families. The 8 different families have been selected in order to identify the different family lives and the various household labor patterns that are conducted by both the working husband and the working wife. As a result, we have found out that working wives still had to manage their time in an extremely busy manner in order to balance their professional work with their household tasks. However, the household work that was being shared by the husbands also seemed to vary dynamically according to the different family situations. Although, it has shown that household tasks are divided by the person's sex, the amount of household tasks that are shared tended to increase according to the life cycle of each family.

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