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혀에 발생한 랑게르한스 세포 조직구증: 증례 보고 및 문헌 고찰
김근전,선동일,신현일,김상연 대한이비인후과학회 2023 대한이비인후과학회지 두경부외과학 Vol.66 No.1
Langerhans cell histiocytosis (LCH) is commonly characterized by abnormal function anddifferentiation or proliferation of monocytes. In LCH, granulomatous lesions, including langerine-positive histocytes and inflammatory infiltrates, can occur at all tissues, particularly thebones, skin, lungs, and pituitary gland. Thirty nine-year-old male patient visited outpatientclinic with a mass on his tongue that had been presented one month prior. The initial size was2×1.5 cm, but it gradually grew larger. The authors performed an incisional biopsy under localanesthesia, and the pathological diagnosis confirmed that LCH of the tongue. Several studiesincluding bone marrow biopsy were performed to assess involvement of other organs. These tests show that only the tongue was involved in this case. The patient underwent furthertreatment with low-dose radiotherapy. We present this case of tongue LCH with a review ofthe literature.
김근전,주영훈 대한후두음성언어의학회 2022 대한후두음성언어의학회지 Vol.33 No.3
The coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe acute respiratory syndrome coronavirus-2 has upended the world of otolaryngology. After COVID-19 infection, patients experience various complication of symptoms due to injury of the larynx and lung/ respiratory system. Regardless of the patient’s severity, patients can experience several complications including dysphonia, vocal cord paralysis/paresis and sensory neuropathy. An emerging role for otolaryngologists in the coming weeks and months is the management of laryngeal complications of COVID-19. This review is intended to describe laryngeal complications in patients recovering from COVID-19 infection.
두경부 암 환자에서 수술 전 호중구-림프구 비율의 임상적 효용성
김근전,강준명,서재현,황세환,윤호영,진호준,강하람,이현호,주영훈 대한이비인후과학회 2020 대한이비인후과학회지 두경부외과학 Vol.63 No.1
Background and Objectives To investigate the prognostic value of the neutrophil to lymphocyteratio (NLR) in patients with head and neck squamous cell cancer (HNSCC). Subjects and Method Clinical data from 259 patients with HNSCC were collected retrospectively. NLR was adopted as potential prognostic biomarkers. Results NLR was associated with cancer recurrence (p=0.002 and p<0.001, respectively). Patients with a NLR >2.15 had significantly decreased 5-year disease specific survival (DSS)based on the Kaplan-Meier survival curves (p<0.001 and p=0.029, respectively). The MultivariateCox regression analysis confirmed a significant association between 5-year DSS and theNLR (using 2.15 as the cut-off; hazard ratio, 1.852; 95% confidence interval, 1.237-2.771; p=0.003). Conclusion A NLR cut-off value ≥2.15 was associated with adverse outcomes in patientswith HNSCC.