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      • SCOPUSKCI등재
      • SCOPUSKCI등재

        기저 세포암에서 혈장 fibronectin 발현에 관한 면역 조직 화학적 연구

        강인경(In Kyung Kang),정병수(Byung Soo Chung),최규철(Kyu Chul Choi) 대한피부과학회 1992 大韓皮膚科學會誌 Vol.30 No.2

        Previous observations have demonstrated that fibronectia (FN) is deposited high abundance in basal cell carcinoma (BCC) stroma. Since FN is a glycoprotein which promotes interaction between cells and extracellular matrix, it may been important component of slowly expansile carcinoma such as BCC. Furthermore, BCCs aggressiveness varies with it's histologic appearance. The authors investigated distribution of plasma FN (pFN) in 8 BCC cases with various histologic types (3 nodulocystic type, 2 infiltrative type, 2 keracotic type, 1 adenoid type) and 4 squamous cell carcinomas (SCC), which have a more aggrcisive biologic behavior than BCC using immunohistochemical staining. In normal skin, pFN was strongly positive at the clenzoepidermal junction and perivascular area with a linear pattern, and in the papillary dermis with a reticular pattern, and was weakly positive in the reticular dermis. In BCC, pFN was strongly positive in nodulocystic BCC, with the highest concentration along the periphery of the tumor island in a filamentous pattern, .hereas, it was moderately positive in adenoid, keratotic, infiltrative BCC stroma. In SCC, pFN was weakly positive around tumor the margins with a thin, coarse deposition These results show that with epidermal tumors, the degree of the pFN expression in stroma is propotional to their aggressiveness. (Kor J Dermatol 1992;30(2): 155-161)

      • KCI등재

        뉴미디어 환경에서 공간디자인 프로세스 변화에 관한 연구

        강인경(Kang, In-Kyung),윤재은(Yoon, Jae-Eun) 한국실내디자인학회 2009 한국실내디자인학회논문집 Vol.18 No.6

        User and media are in close coalition with each other in the 21st century’s era of New-Media. The new users exposed to the New-Media environment have a complete understanding of the digital media environment, and are also taking on the role of an active identity in the formation of culture in new media. In the field of spatial design, creative spatial interfaces designed through various methods derived from the New-Media environment and technology that weren’t even imaginable in the past ultimately came to exist in a mutual relationship with the user, the people. This study is in the same context as studies looking into the establishment of design in media art and digital media space in the New-Media environment. Media art is an outcome arising from the demand towards new art combined with the attempts towards accepting various media as a means for artistic expression. Media art seizes to being a mere part of art, but more. This study aims to look into the theoretical basis of New-Media and define the design process through the expressional characteristics and triggered thoughts thereof. Lastly, the results of the research will be put together to produce the final results. Such analysis process will be the basis of the creation of a new paradigm and spatial thought, and allow people to be concerned about the various changes in spatial formation.

      • SCOPUSKCI등재

        에크린 한성종양에서 세포각질 폴리펩타이드의 발현에 관한 연구

        강인경 ( In Kyung Kang ),김웅 ( Oong Kim ),최규철 ( Kyu Chul Choi ) 대한피부과학회 1996 大韓皮膚科學會誌 Vol.34 No.1

        Background: Different distributions of cytokeratins (CKs) have been found in various layers of the epidermis and in the structure of cutaneous appendages. Benign tumors of the epidermis or cutaneous appendages usually retain the characteristic distribution of CKs of their origin. Objective and Method: To elucidate the nature and differentiation of various eccrine gland tumors, we performed immunohistochemical staining using a panel of monoclonal antibodies against CKs in a normal eccrire gland, syringoma, eccrine hidrocystoma, eccrine poroma and clear cell hidradenoma. The tissue distribution of various keratins in the normal eccrine gland was compared with that in varioas eccrine gland tumors. Results : With regard to CKs expression, the results indicated that syringoma represents a tumor differentiating toward both the uppermost part of the dermal duct and the lower intraepidermal duct, and eccrine hidrocystoma represents a tumor differentiating toward the luminal cell of the dermal duct of the eccrine gland. Eccrine poroma cells seemed to be most closed related to the uppermost dermal duct of eccrine gland. We also found that analyse distribution of CKs was insufficient to elucidate the histogenesis of clear cell hidradenoma. Conclusion : Analysing CKs is helpful in the analysis of epidermal neoplasms with differentiation toward the eccrine gland. (Kor J Dermatol 1996;34(1): 78-84)

      • SCOPUSKCI등재

        피부이완의 소견을 보인 탄력섬유성 위황색종

        강인경(In Kyung Kang),정병수(Byoung Soo Chung),김영조(Young Cho Kim),최규철(Kyu Chul Choi) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.3

        We report herein a case of pseudoxanthoma elasticum(PXE) in a 24 year old woman. She had a generalized laxity of the skin which tended to hang in folds along the sides of the trunk and in the axillary areas. There was no similar skin lesion in her family. Histopathological examination revealed clumping and fragmentation of the elastic fibers in the mid and lower dermis. Von Kossa stain showed dense deposition of calcium in these areas. We suspect this case as autosomal recessive type II PXE. (Kor J Derrnetol 20(3}: 423 42l,1S91)

      • KCI등재

        초등학생이 지각한 정서지능, 자기효능감, 자기주도적 학습태도 간의 구조분석

        강인경(Kang, In-kyung),김춘경(Kim, Choon-kyung) 학습자중심교과교육학회 2014 학습자중심교과교육연구 Vol.14 No.12

        본 연구에서는 초등학교 고학년 학생들이 지각한 정서지능과 자기효능감, 자기주도적 학습태도 간의 구조적 관계를 분석하였다. ○○시 소재 초등학교 5∼6학년 444명을 대상으로 연구하였다. 연구방법은 중다회귀분석을 통해 정서지능과 자기효능 감 간의 관계를 살펴보았으며, 구조적 분석을 통해 정서지능과 자기효능감, 자기주도적 학습태도 간의 관계를 살펴보았다. 연구 결과는 첫째, 정서지능의 하위변인인 정서 사고촉진, 감정이입, 정서인식 및 표현이 자기주도적 학습태도에 유의미한 영 향을 미치는 것으로 나타났다. 둘째, 세 가지 변인들 간의 관계에서 직접 효과가 모두 성립되었으며, 정서지능은 자기주도적 학습태도에 대해 직접적인 효과 뿐만 아니라 자기효능감을 통해 간접적인 효과도 유의미한 것으로 나타났다. 이러한 연구를 통해 자기주도적 학습태도를 향상시키기 위한 개인 내적인 변인들 간의 관계에 대해서 탐구할 수 있었으며, 교육 현장에서 자기주도적 학습태도를 향상시키기 위해 제공되어야 할 요소들에 대해서 탐색하는데 기여하고자 하였다. The purpose of this study is to investigate the structural relationship among Emotional Intelligence, Self-efficacy, Self-directed learning Attitudes perceived by elementary school children. 444 students from 5th to 6th grade in ○○ city were surveyed vis-avis questionnaires. The main results were as follows: Firstly, In the multiple regression analysis which investigated the effects of promotion of emotional thought, empathy, recognition and expression of emotion has a significant positive effect on Self-directed learning Attitudes. Secondly, Emotional Intelligence and Self-efficacy perceived by elementary school students are significant internal variables directly affecting Self-directed learning Attitudes. Emotional Intelligence is the significant internal variable directly affecting Self-efficacy. and Self-efficacy is also the intervening variable between Emotional Intelligence perceived by elementary school students and Self-directed learning Attitudes. Through this study was to study the relationships between Emotional Intelligence, Self-efficacy to improve Self-directed learning Attitudes, and willing to study the factors that should be enhance the self-directed learning attitude in our education.

      • KCI등재

        청소년의 또래애착이 삶의 만족도를 매개로 자기조절학습능력에 미치는 영향에 대한 종단연구

        강인경(In Kyung Kang),김춘경(Choon Kyung Kim) 한국교육심리학회 2016 敎育心理硏究 Vol.30 No.2

        본 연구의 목적은 시간의 흐름에 따른 청소년의 또래애착, 삶의 만족도, 자기조절학습능력의 변화양상을 살펴보고, 또래애착과 자기조절학습능력 간의 관계에서 삶의 만족도의 매개효과를 검증하는것이다. 본 연구에서는 중학교 1학년 한국아동.청소년패널(KCYPS)의 1차, 3차, 5차년도 1,539명의 자료를 사용하였으며, 잠재성장모형을 적용하여 모형을 분석하였다. 연구 결과는 다음과 같다. 첫째, 중학교 1학년에서 고등학교 2학년시기의 또래애착, 삶의 만족도, 자기조절학습능력은 시간의 흐름에 따라 증가하는 양상을 보였다. 둘째, 중학교 1학년의 또래애착이 높아질수록 삶의 만족도와 자기조절학습능력 또한 향상되는 것으로 나타났으며, 중학교 1학년부터 고등학교 2학년 시기 동안 또래애착 수준이 더 크게 높아질수록 삶의 만족도와 자기조절학습능력이 더 높아지는 것으로 나타났다. 셋째, 또래애착과 자기조절학습능력의 초기값 간의 관계에서 삶의 만족도의 매개효과는 유의미하였으나 또래애착과 자기조절학습능력 간의 관계에서 삶의 만족도의 종단매개효과는 유의하지 않은 것으로 나타났다. 마지막으로 본 연구결과의 시사점과 추후 연구를 위한 제언 등에 대해 논의하였다. The purpose of this study was to investigate longitudinal changes of adolescents`` Peer attachment, Life satisfaction, Self-Regulation Learning ability levels and the predictive effect of the relevant variables. This study used the data from the Korean Children and Youth Panel Survey(KCYPS: utilizing the data from the middle school 1st, 3rd, 5th year cohorts)was used and analyzed through latent growth models. The results were as follows. First, the level of Peer attachment, Life satisfaction, Self-Regulation Learning ability increased a time passed. The results also analyzed by the Latent Growth Curve Model revealed that adolescents`` Peer attachment had a positive effect on the Life satisfaction and Self-Regulation Learning ability. Life satisfaction also had positive effect on the Self-Regulation Learning ability. In addition, Peer attachment is the rate of change had significant influence on Life satisfaction, Self-Regulation Learning ability rate. Finally, suggestions for future research were discussed based on limitations of this study.

      • SCOPUSKCI등재

        악성 변화를 보인 첨규 콘딜롬

        김웅 ( Oong Kim ),강인경 ( In Kyung Kang ),최규철 ( Kyu Chul Choi ) 대한피부과학회 1995 대한피부과학회지 Vol.33 No.4

        Condyloma acuminatum occurs in perianal and genital area by infection of human papillomavirus (HPV) and appeais as fairly soft verrucous papules or a cauliflower-like mass. So far 60 HPV types have been identified. Among them, condyloma acuminatum is predomi-nantly associated with HPV 16, 18 and rarely with 16, 18. HPV 16, 18 is regarded as a high-risk HPV infection because of the association of HPV 16, 18 with Bowens disease, cervical cancer, and anogenital cancer. In additioin, a significant appearance of cervical anaplastic lesions is preceded by condyloma acuminatum and a high prevalence of cervical dysplasia has been found in female consorts of men with geriital warts. Malignant transformation has been observed in rare incidences of condyloma acumina a on the external genitalia. We present a case of condylc ma acuminatum showing malignant transforrnation. The patient also has uterine cervical carcinonia. We detected HPV 16 in the lesion using polymerase chain reaction. (Kor J Dermatol 1995;33(4): 759-763)

      • SCOPUSKCI등재

        피부의 섬유종양들에서 Factor Xllla , CD34 및 Mac 387의 표현에 관한 면역조직화학적 연구

        정헌 ( Hun Jung ),강인경 ( In Kyung Kang ),최규철 ( Kyu Chul Choi ) 대한피부과학회 1995 大韓皮膚科學會誌 Vol.33 No.6

        Background : The relationship and differentiation among various dendritic cells of the dermis are unclear. Recently it has hecome possible to identify different subpopulat,ions of dermal dendritic cells using anti-CD34 and anti-factor XIIIa antibodies. Objective : To elucidate which cell types the fibrous dermal turnors consist of we compared the staining patterns of these antibodies as well as of anti-Mac 387 antibody which are labeled as inflammatory cells of the monocyte-macrophage lineage. Methods : Tumors studied included dermatofibrosarcoma protuberans(DFSP, n=2), dermato-fibroma(n=::22), neurofibroma, n=27), acrochordon(n=15), keloid, hypertrophic scar(n=10), juvenile xanthogranuloma(n=1, and malignant fibrous histiocytoma (MFH, n=1). We performed immunoperoxidase staining(AUSC technique) with polyclonal anti FXIIIa antibody, monoclonal anti-CD34 antibody, and monoclonal anti-Mac 387 antibody on the formalin-fixed-paraffin-embedded tissue specimens of these fibrous tumors. The intensity of staining was graded as negative, weakly staining, or strongly stainiring. Results : FXIIIa reactivity was strongly present in dendritic and spindle-shaped cells of all dermatofibromas and some nurofibromas(11 of 27 specimens), but absent from the other fibrous tumors. Among these tumors, one of the two DFSPs was uniquely expressed CD34. Dendritic and spindle-shaped cells within tiese tumors were MAC 387 negative. In inflammatory conditions, variable numbers of MAC 38 positive cells were observed, corresponding to histiocytes and mac-rophages, but the labeling of ipithelioid cells and multinucleated foreign body giant cells were variable. Conclusion : The findings of significant numbers of FXIIIa positive cells in dermal fibrous tumors studied suggest that thet may be diagnostic utility associated with the use of this antit)ody. In addition, CD 34 expression by the tumor cells can be an extremely useful marker in establishing a definitive diagnosis of IFSP. (Kor J Dermatol 1995;33(6): 1038-1045)

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