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강원구,김운환,박중신,김재철,Gang, Won-Gu,Kim, Un-Hwan,Park, Jung-Sin,Kim, Jae-Cheol 한국전기기술인협회 1999 電力技術人 Vol.206 No.10
최근들어 급속히 보급된 전자 및 정밀기기의 보편적 이용은 전력품질에 관한 수용가의 인식을 점차적으로 고조시키고 있다. 무엇보다도 전압 크기의 품질은 수용가측에 직접적인 영향을 줄 수 있는 가장 중요한 전력품질 문제이다. 그러나 전력품질 부분에 대한 전력기술인들의 인식은 수년전에 비해 크게 향상되지 못하고 있는 것 또한 현실이다.
강원구 한국전기기술인협회 1998 電力技術人 Vol.194 No.10
일본에서 자가용 전기서비 기술자들에게 제일 소중하게 여겨지는 전기설비에 관한 기술기준을 정한 통칭 전기설비 기술기준이 1997년 3월 27일에 전면 개정되어 공포되었다.
Clarithromycin 정제의 생물학적 동등성 및 약물동태
강원구,박선영,박용순,권광일,우종수,최경업 한국임상약학회 1999 한국임상약학회지 Vol.9 No.1
This study was carried out to compare the bioavailability of Hanmi clarithromycin (250 mg/tablet) with that of The bioavailability was examined on 20 volunteers who received a single dose (500 mg) of each drug in the fasting state in a randomized balanced 2-way crossover design. After dosing, blood samples were collected for a period of 12 hours. Plasma samples were analyzed for clarithromycin and roxithromycin(internal standard) by HPLC/Coulometric BCD. The pharmaco-kinetic parameters (, Cmax, Tmax, , Ka, Kel, , Vd/F and Cl/F) were calculated from the plasma clarithromycin concentration-time data of each volunteer. The computer program 'WinNonlin' was used for compartmental analysis. One compartment model with first-order input, from order output with lag time, weighting factor was chosen as the appropriate pharmacokinetic model. The major pharmacokinetic parameters (, Cmax and Tmax) of Hanmi clarithromycin were , respectively, and those of , respectively. The differences in mean values of and Cmax between two products were , respectively. The least significant differences at for and Cmax were , respectively. Though the plasma clarithromycin concentrations of Hanmi clarithromycin were higher than those of at all observed times, the bioavailability of Hanmi clarithromycin appeared to be bioequivalent with that of . The Ka, Kel, , Vd/F and Cl/F of the Hanmi clarithromycin were , respectively, and those of , respectively. There were no statistically significant differences between two drugs in all pharmacokinetic parameters.