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김성배(Sung Bae Kim),변정란(Jeong Ran Byun),강성인(Sung In Kang),강덕희(Duck Hee Kang),성연아(Yeon Ah Sung),신길자(Gil Ja Shin),이우형(Woo Hyung Lee),경난호(Nan Ho Kyung) 대한내과학회 1991 대한내과학회지 Vol.40 No.3
N/A Doppler echocardiagrams of the mitral and tricuspid valve were recorded along with electrocardiograms from 32 non-insulin dependent diabetes and 17 normal subjects (1) to determine whether a relation existed between the microangiopahtic complications and the patterns of diastolic filling. (2) to evaluate the diastolic LV&RV filling characteristics in non-insulin dependent diabetic patients, and correlation between LFKRV filling parameters. The diabetics were divided into 3 groups according to the number of microangiopathic complications i.e., peripheral neuropathy, nephropathy, retinopathy. (Group I:10 cases without complications Group II:12 cases with 1, 2 complications Group III:10 cases with 3 complications) The results were as follows. 1) No significant difference was found among groups for PFVE 8r, AT in Lt&Rt ventricular filling pattern. 2) PFVA in control (Lt:53.64±16.88, Rt:30.23±7.54) and Group L(Lt:57.4±15.02, Rt:38.44±8.58) were significantly decreased (Lt:p<0.005, p<0.025, Rt:p<0. 005, p<0.05) compared to Group III (Lt:71.8±15.24, Rt: 44.6±89) 3) E/A ratio in contro (Lt:1.30±0.33+Rt:1.59±0.28) and Group I(Lt:1.09±0.28, Rt:1.27±0.35) were significantly increased (Lt:p<0.005,p<0.05, Rt:p<0,05, p<0.05) compared to Group III(Lt:1.11±0.28), 4) DT was prolonged in groups with more microgagniopathic complication, but it showed no significant differences among groups(p>0.05). 5) There was a significant correlation in PFVE, E/A ratio, deceleration time between the left and right ventricular inflow pattern, (r=0.56, 0.60, 0.47 respectively) Data indicated that indexes of RV diastolic dysfunction were closely related to corresponding LV diastolic filling parameters (PFVE, E/A ratio, DT), and a correlation existed between diabetic microangiopathic complications and diastolic filling pattern.