기저세포모반증후군 두 증례

김재덕,서요섭,김진수 대한구강악안면방사선학회 2008 Imaging Science in Dentistry Vol.38 No.2

The basal cell nevus syndrome (BCNS) is an autosomal dominant disorder, characterized by basal cell carcinomas, odontogenic keratocysts and skeletal abnormalities. We experienced two cases that represented several characteristics of BCNS. Case 1: a thirty three year-old man visited CSU hospital. His radiographs showed four cystic lesions at both maxillary sinus and both mandibular angle, with bifid rib and ectopic calcification of falx cerebri. After marsupialization and enucleation, recurrent and newly developing tendency were found on his follow-up radiographs. Case 2: a seventeen year-old man had four large cystic lesions which were diagnosed as odontogenic keratocysts. He had craniofacial anomalies which included ectopic calcification and frontal bossing.

Case Report : Periosteal osteoblastoma of the mandible mimicking an osteoma: Case report

( Yo Seob Seo ),( Jae Duk Kim ),( Jin Soo Kim ) 조선대학교 구강생물학연구소 2013 Oral Biology Research (Oral Biol Res) Vol.37 No.2

Osteoblastomas are uncommon tumors that account for approximately 1% of all primary bone tumors. This report presents the cone-beam computed tomography (CBCT) findings of an osteoblastoma of the coronoid process of the mandible. Initially, this lesion was judged as an osteoma. CBCT images revealed a large mass with multiple internal calcifications. Histopathological examination of the lesion confirmed it as an osteoblastoma.

Pretreatment of Eruca Sativa Attenuates Ocular Inflammation and Endoplasmic Reticulum Stress in Human Retinal Pigmented Epithelium Cells

Yo Seob Kim,Hea-Yeon Yun,JiSu Lee,Jung-Heun Ha,Misook Kim,Youngseung Lee,Yoonhwa Jeong 한국식품영양과학회 2020 한국식품영양과학회 학술대회발표집 Vol.2020 No.10

Oxysterol 25-hydroxycholesterol as a metabolic pathophysiological factors of osteoarthritis induces apoptosis in primary rat chondrocytes

Yo-Seob Seo,In-A Cho,Tae-Hyeon Kim,Jae-Seek You,Ji-Su Oh,Gyeong-Je Lee,Do Kyung Kim,Jae-Sung Kim 대한생리학회-대한약리학회 2020 The Korean Journal of Physiology & Pharmacology Vol.24 No.3

The aim of the present study was to investigate the pathophysiological etiology of osteoarthritis that is mediated by the apoptosis of chondrocytes exposed to 25-hydroxycholesterol (25-HC), an oxysterol synthesized by the expression of cholesterol-25-hydroxylase (CH25H) under inflammatory conditions. Interleukin-1β induced the apoptosis of chondrocytes in a dose- dependent manner. Furthermore, the production of 25-HC increased in the chondrocytes treated with interleukin-1β through the expression of CH25H. 25-HC decreased the viability of chondrocytes. Chondrocytes with condensed nucleus and apoptotic populations increased by 25- HC. Moreover, the activity and expression of caspase-3 were increased by the death ligand-mediated extrinsic and mitochondria-dependent intrinsic apoptotic pathways in the chondrocytes treated with 25-HC. Finally, 25-HC induced not only caspasedependent apoptosis, but also induced proteoglycan loss in articular cartilage ex vivo cultured rat knee joints. These data indicate that 25-HC may act as a metabolic pathophysiological factor in osteoarthritis that is mediated by progressive chondrocyte death in the articular cartilage with inflammatory condition.

상상 어린이 공원 등에 설치된 야외 아동용 자가발전 운동기구의 에너지소비량 대한 연구

김요섭 ( Yo Seob Kim ),조세환 ( Se Hwan Cho ) 서울敎育大學校 初等敎育硏究所 2012 한국초등교육 Vol.23 No.4

이 연구는 서울시 상상어린이 공원이나 근린공원 등에 설치된 아동의 표준 체형에 맞도록 설계되어진 야외 아동용 운동기구들의 운동강도 수준을 비교 평가하고 에너지소비량을 파악하여 아동에게 효과적인 운동정보를 제공하기 위하여 수행하였다. 이를 위해 수도권에 위치한 초등학교에 재학 중인 2~4 학년생 중 본 연구를 수행하기 힘든 질환자나 고도 비만자를 제외한 아동을 대상으로 선별된 아동용 일반 운동기구 3 종과 기능성 게임형 운동기구 2 종의 운동기구를 각각 저강도, 중강도, 고강도로 구동하게 하고 운동 중 산소섭취량과 에너지소비량을 산출하여 운동기구의 운동강도 및 운동량을 비교 평가하였다. 연구 결과, 일반 운동기구 3 종에 대한 운동량 평가는 남· 여 아동 모두 사이클 운동이 가장 높은 에너지소비량을 보였으며 크로스컨트리와 롤링웨이스트 순으로 평가되었다. 일반 운동기구와 시나리오를 갖는 기능성 게임형 운동기구를 비교하였을 때 기능성 게임형 운동기구가 약 20% 이상 높은 에너지소비량을 보였으며, 기능성 게임형 운동기구들을 비교한 결과 레이싱형 운동기구가 타겟팅형 운동기구보다 평균 5.6% 이상 높은 운동효과를 나타냈다. 운동기구들의 운동강도 수준은 남자 아동의 경우 53%~79%, 여자 아동의 경우 54%~77%로 평가되었다. 이상의 결과를 종합해 보면 야외 아동용 운동기구는 분당 2.2~5.9 kcal 의 에너지 소비량을 가지며 일반 운동기구보다 기능성 게임형 운동기구가 운동이 부족한 아동들이 야외에서 재미있게 운동하면서 높은 운동효과를 볼 수 있다고 판단된다. This study is to find momentum of children`s outdoor exercise equipment installed in urban neighborhood parks like Seoul Sangsang Kids Parks by measuring energy consumption and exercise intensity according to the exercise stage of the equipment. This children`s outdoor exercise equipment is designed to fit children`s standard body type. 2nd~4th grade students in a elementary school located in capital area are selected as subjects and students who have trouble with involving in the research and very obese student were left out from the research. To test graded exercise intensity application of children`s outdoor exercise equipment, exercise tolerance test is done by setting 3 standards; low, medium and high intensity. Oxygen uptake and energy consumption of the subjects are measured and estimated through using three kinds of usual exercise equipment and functional game-based children`s outdoor exercise equipment. The results of this study are listed below. First, if students use three kinds of usual exercise equipment, stationary bikes consume energy the most and cross-country and rolling-waist are the secondary and thirdly energy-cousuming exercise equipment. Second, the functional game-based exercise equipments consume 20% more energy than usual exercise equipment. Third, a comparison on results of the functional game-based exercise equipments shows that racing-style exercise equipments consume 5.6% more energy than targeting-style exercise equipments. As for the results described above, the exercise using outdoor exercise equipment requires 2.2~5.9 kcal energy consumption per minute and the functional game-based exercise equipments can be used more effectively than usual exercise equipment. Children who are short of exercise can enjoy exercising outdoors and get high beneficial effects of exercise with functional game-based exercise equipments.

아동학대에 대한 부모의 태도 조사: 장애아동 부모와 일반아동 부모의 비교

김요섭 ( Yo Seob Kim ),최영종 ( Yung Jong Choi ) 대구대학교 한국특수교육문제연구소 2007 특수교육저널 : 이론과 실천 Vol.8 No.3

The purpose of this study was twofold. First, it investigated whether children with disabilities are more at risk of being abused by their parents than children without disabilities through parent attitude questionnaire toward child abuse. Second, it also examined whether there was difference in parent attitudes toward child abuse according to children``s gender, parental education level, and family income. 113 parents of children with disabilities and 105 parents of children without disabilities were participated. A survey composed of 3 categories including 60 questions of child abuse behaviors was used. The results were as follows. First, both parent groups generally showed very negative attitudes toward child abuse. Second, in comparison between two parent groups, parents of children with disabilities took more negative attitudes toward child neglect than those of children without disabilities. That meant children with disabilities are less at risk of being neglected by their parents than children without disabilities. In both groups, there was no differences found in parent attitudes toward child abuse according to children``s gender, parental education level, or family income. Discussions about why parents of children with disabilities took more negative attitudes toward child neglect than those of children without disabilities were provided.

판례를 통하여 본 LRE 규정의 해석 및 배치 결정 요소의 고찰

김요섭 ( Yo Seob Kim ) 한국정서.행동장애아교육학회(구.한국정서학습장애아교육학회) 2006 정서ㆍ행동장애연구 Vol.22 No.4

다운증후군 아동 얼굴성형수술에 대한 교사의 견해 조사

김요섭 ( Yo Seob Kim ),박소영 ( So Young Park ) 한국특수아동학회 2009 특수아동교육연구 Vol.11 No.3

조사야에 따른 cone-beam computed tomography의 흡수선량 비교

서요섭 ( Yo Seob Seo ),김재덕 ( Jae Duk Kim ),김진수 ( Jin Soo Kim ) 조선대학교 치의학연구원 2013 Oral Biology Research (Oral Biol Res) Vol.37 No.1

To compare absorbed doses of cone-beam computed tomography (CBCT) according to field of view (FOV). Materials and Methods: To measure the absorbed doses of CBCT (Hitachi Medical Co.), we placed thermoluminescent dosimeter chips on both the submandibular and parotid glands, esophagus, tongue, and thyroid gland in a dental head phantom (CIRS). We used three image acquisition modes with FOV of different size: panoramic mode (P mode), implant mode (I mode), and dental mode (D mode). Two different dental mode scans were performed. One scanned the right upper molar region (D1), whereas the other scanned the left lower molar region (D2). Results: Average absorbed doses was lowest in D mode (average of D1 and D2, 4272.1 μGy) (p<0.05). Although the averages of absorbed doses between D1 and D2 showed no significant difference (p>0.05), the absorbed doses of esophagus (D1 756.9 μGy, D2 2938.2 μGy) and thyroid gland (D1 344.6 μGy, D2 880.1 μGy) were significantly different between D1 and D2. Conclusion: Since the average of absorbed doses was lowest with the smallest FOV, we must try to select the lowest FOV as possible when performing computed tomography, followed by careful diagnosis.

아동학대에 대한 장애아동 부모와 일반아동 부모의 인식 비교 연구

김요섭 ( Yo Seob Kim ) 한국특수아동학회 2011 특수아동교육연구 Vol.13 No.4

The purpose of the present study was twofold. First, it investigated the degree of awareness toward child abuse behaviors, causes of child abuse, knowledge of reporting agencies and their phone number for an abused child, and the necessity of parent education for child abuse prevention, in the parents of children with and without disabilities. Second, it also examined whether there was difference in the degree of awareness between the two groups toward those factors. A 243 parents of children with disabilities and a 308 parents of children without disabilities participated for this study, and a survey was used to collect data. The results were as follows. First, both parent groups generally were aware of various child abuse behaviors composed of 3 categories including neglect, emotional abuse, and physical abuse. However, in the comparison of both groups, the parents of children with disabilities were more significantly aware of the physical abuse than those of children without disabilities. Second, both groups showed very similar response in their awareness of the causes of child abuse except that parents of children with disabilities agreed more on the factor of having unexpected child than those of children without disabilities. Third, both groups had little knowledge about reporting agencies and their phone numbers, and there was no difference between the two groups in their degree of knowledge for this factor. Finally, most parents of both groups agreed on the necessity of parent education programs for child abuse prevention. Discussion for the results was provided.