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      • KCI등재

        조경기법으로 본 중국원림의 풍수지리사상

        ( Wen Dong Yu ),( Tai Ho Kang ) 한국전통조경학회(구 한국정원학회) 2014 한국전통조경학회지 Vol.32 No.3

        본 연구는 중국 원림의 조경기법에서 배치, 축 대칭, 주종(主從) 관계, 공간 대조, 경관 은폐 등으로 나타나고 있는 풍수지리 사상인 "혈효응(穴效應)", "용사효응(龍砂效應)" 및 "수구효응(水口效應)" 의 이론을 파악하고 원림 공간에서의 표현 방식에 대해 고찰하고자 하였다. 대해 고찰하고자 하였다. 배치 방식을 증명하기 위하여 사합원(四合院)과 소주 망사원(網師園)을 대상으로 하였으며, 축 대칭과 주종(主從) 관계를 증명하기 위하여 명·청대 북경성과 자금성, 운남성 선위시(宣威市) 도시 광장 설계를 대상으로 분석하였고, 공간 대조와 경관 은폐 방식을 증명하기 위하여 소주 유원(留園)과 창랑정(滄浪亭), 졸정원(拙政園), 태안시 남호공원을 대상으로 분석하였다. 연구 방법은 문헌조사와 현지답사 및 사례 분석으로 나누어 진행하였으며 연구 결과는 다음과 같다. 첫째, 배치 방식은 사합원, 소주 망사원 등에서 중국 풍수지리사상의 "혈효응"이 적용되었으며, 둘째, 축 대칭과 주종관계는 명·청대 북경성의 도시 계획과 자금성 공간 배치에서 풍수지리사상의 "용사효응"이 적용되었으며, 운남성 선위시 도시 광장 설계 등 중국 현대 조경 설계기법에도 풍수지리사상을 도입하고 있다. 셋째, "수구효응"은 공간 대조 기법과 경관 은폐 기법에서 나타나고 있다. 이는 소주 유원(留園), 창랑정(滄浪亭), 졸정원(拙政園), 태안시 남호공원 등의 설계에 도입되었다. This study aimed to grasp Feng Shui Geographical Thought appears in layout, Axial symmetry, hierarchical planning, spatial composition and hidden design techniques of Chinese Garden, that is "Xue effect", "Long-Sha effect" and "Shuikou effect", and to study on expression in Landscape Space. The Author selected the Chinese courtyard and the Nets Garden as the object to prove the Layout landscaping techniques; and selected Beijing in Ming and Qing Dynasties and the Forbidden City, A square design in Xuanwei as the object to prove the Axial Symmetrical and Hierarchical landscaping techniques, and also selected the Lingering G-arden and the Gentle Waves Pavilion, Humble Administrator``s Garden in Suzhou, and Nanhu Park in Taian as the object to prove the Spatial Composition and Hidden design techniques. The methods of this article is combined Literature survey and Field survey with Case analysis to draw the conclusions as follows: First, "Xue effect" of Chinese Feng Shui Geographical Thought is suitable for the layout of Chinese courtyard and the Nets Garden in Suzhou; Second, "Long-Sha effect" is suitable for the urban planning of Beijing in Ming and Qing Dynasty, and the layout of the Forbidden City, by the city square design in Xuanwei, we can see that it is also suitable for Chinese modern landscape design; Third, "Shuikou effect" is appeared in the Spatial Composition and Hidden design techniques. All of these landscape design techniques are commonly used in China``s modern landscape. It has been proved by the analysis of the Lingering Garden and the Gentle Waves Pavilion, Humble Administrator``s Garden in Suzhou, and Nanhu Park in Taian.

      • KCI등재

        From Landscaping Techniques to Study the Feng Shui Geographical Thought in Chinese Garden

        Yu, Wen-Dong,Kang, Tai-Ho 한국전통조경학회 2014 한국전통조경학회지 Vol.32 No.3

        본 연구는 중국 원림의 조경기법에서 배치, 축 대칭, 주종(主從) 관계, 공간 대조, 경관 은폐 등으로 나타나고 있는 풍수지리사상인 "혈효응(穴效應)", "용사효응(龍砂效應)" 및 "수구효응(水口效應)" 의 이론을 파악하고 원림 공간에서의 표현 방식에 대해 고찰하고자 하였다. 배치 방식을 증명하기 위하여 사합원(四合院)과 소주 망사원(網師園)을 대상으로 하였으며, 축 대칭과 주종(主從) 관계를 증명하기 위하여 명 청대 북경성과 자금성, 운남성 선위시(宣威市) 도시 광장 설계를 대상으로 분석하였고, 공간 대조와 경관 은폐 방식을 증명하기 위하여 소주 유원(留園)과 창랑정(滄浪亭), 졸정원(拙政園), 태안시 남호공원을 대상으로 분석하였다. 연구 방법은 문헌조사와 현지답사 및 사례 분석으로 나누어 진행하였으며 연구 결과는 다음과 같다. 첫째, 배치 방식은 사합원, 소주 망사원 등에서 중국 풍수지리사상의 "혈효응"이 적용되었으며, 둘째, 축 대칭과 주종관계는 명 청대 북경성의 도시 계획과 자금성 공간 배치에서 풍수지리사상의 "용사효응"이 적용되었으며, 운남성 선위시 도시 광장 설계 등 중국 현대 조경 설계기법에도 풍수지리사상을 도입하고 있다. 셋째, "수구효응"은 공간 대조 기법과 경관 은폐 기법에서 나타나고 있다. 이는 소주 유원(留園), 창랑정(滄浪亭), 졸정원(拙政園), 태안시 남호공원 등의 설계에 도입되었다. This study aimed to grasp Feng Shui Geographical Thought appears in layout, Axial symmetry, hierarchical planning, spatial composition and hidden design techniques of Chinese Garden, that is "Xue effect", "Long-Sha effect" and "Shuikou effect", and to study on expression in Landscape Space. The Author selected the Chinese courtyard and the Nets Garden as the object to prove the Layout landscaping techniques; and selected Beijing in Ming and Qing Dynasties and the Forbidden City, A square design in Xuanwei as the object to prove the Axial Symmetrical and Hierarchical landscaping techniques, and also selected the Lingering G-arden and the Gentle Waves Pavilion, Humble Administrator's Garden in Suzhou, and Nanhu Park in Taian as the object to prove the Spatial Composition and Hidden design techniques. The methods of this article is combined Literature survey and Field survey with Case analysis to draw the conclusions as follows: First, "Xue effect" of Chinese Feng Shui Geographical Thought is suitable for the layout of Chinese courtyard and the Nets Garden in Suzhou; Second, "Long-Sha effect" is suitable for the urban planning of Beijing in Ming and Qing Dynasty, and the layout of the Forbidden City, by the city square design in Xuanwei, we can see that it is also suitable for Chinese modern landscape design; Third, "Shuikou effect" is appeared in the Spatial Composition and Hidden design techniques. All of these landscape design techniques are commonly used in China's modern landscape. It has been proved by the analysis of the Lingering Garden and the Gentle Waves Pavilion, Humble Administrator's Garden in Suzhou, and Nanhu Park in Taian.

      • KCI등재

        연구논문 : GRA를 이용한 경주역사유적지구의 매력성 평가

        우문동 ( Wen Dong Yu ),강태호 ( Tai Ho Kang ) 대한관광경영학회 2015 觀光硏究 Vol.30 No.4

        본 연구는 GRA를 이용하여 경주역사유적지구의 경쟁력을 좌우하는 도시의 매력성을 평가하고자 수행하였다. 이를 위해 선행연구와 UNESCO, ICOMOS 등이 정한 국제 기준을 선정하고 델파이 조사를 통하여 20개의 경주역사유적지구의 매력성 평가지표를 최종적으로 도출하였다. 이들 지표를 바탕으로 GRA를 이용한 평가결과는 다음과 같다. 첫째, 대릉원지구, 월성지구, 남산지구, 황룡사지구, 산성지구의 GRA 분석 평균값은 0.748로 나타나 경주역사유적지구의 전체적인 매력성 수준은 ``강하다``로 평가되었다. 둘째, 지구별 매력성은 월성지구(0.953), 대릉원지구(0.878), 남산지구(0.865), 황룡사지구 (0.561), 산성지구(0.481)로 나타났다. 그 중에 월성지구와 대릉원지구, 남산지구의 매력성 계수 R는 0.800 이상으로 나타나 경주역사유적지구 전체의 매력성에 미치는 영향이 ``매우 강하다``로 평가되었다. 황룡사지구와 산성지구의 계수 R는 0.400~0.600 사이로 나타나 경주역사유적지구 전체의 매력성에 미치는 영향은 ``보통이다``로 평가되었다. This study is an evaluation research based on Gyeongju Historic Heritage Sites to identify the attractive Properties of Gyeongju by GRA, which decided to competitiveness of the historical city. The export Indicator candidate groups were exported by the literature reviews and UNESCO, ICOMOS, and 20 Indicator groups had been selected by delphi method. Based which the results were inferred by GRA. First, The relevant coefficients of Daereungwon District, Wolsong District, Nanshan District, Hwangnyongsa District and The Acidic District are 0.878, 0.953, 0.865, 0.561, 0.481, and the average value is 0.748, which shows the Attractions of Gyeongju Historic Heritage Sites is as a high level. Second, the order of Gyeongju Historic Heritage Sites`` Attractions are Wolsong District(0.953), Daereungwon District(0.878), Nanshan District(0.865), Hwangnyongsa District(0.561), The Acidic District(0.481). And the Attractions of Wolsong District, Daereungwon District, Nanshan District are Very strongly impact on the Attractions of Gyeongju Historic Heritage Sites. And Hwangnyongsa District and The Acidic District are normally impact on it.

      • KCI등재

        경주역사유적지구의 흡인력 평가지표 선정 연구

        우문동 ( Wen Dong Yu ),강태호 ( Tai Ho Kang ) 한국전통조경학회 2015 한국전통조경학회지 Vol.33 No.3

        이 연구는 경주역사유적지구를 대상으로 역사도시경주의 경쟁력을 좌우하는 도시의 흡인력 요인들을 규명하기 위한 평가지표를 개발하고자 수행하였다. 이를 위해 선행연구와 UNESCO, ICOMOS 등이 정한 국제 기준을 검토하여 평가지표 후보군을 도출한 후 델파이 1차, 2차, 3차 전문가 조사를 실시하였으며, 조사 결과에 대한 중요도(M), 표준편차(SD), 내용타당도 지수(CVR), 합의도, 수렴도 등의 분석을 통하여 최종적으로 문화유산의 매력성, 문화유산의 관광자원화, 문화유산관광의 억제력 등 3가지 평가 영역으로 총 42개의 평가지표를 선정하였다. 이들 지표는 역사도시의 흡인력을 제고하기 위한 유용한 기초자료가 될 것으로 판단된다. 앞으로 경주의 흡인력은 이러한 지표를 바탕으로 평가를 수행하여 평가 결과를 검토하며 경주에 대한 흡인력 특성을 재인식할 수 있을 것이다. This study is an evaluation index development research based on Gyeongju Historic Heritage Sites to identify the attractive Properties of Gyeongju, which decided to competitiveness of the historical city. We got the export Indicator candidate groups by the literature reviews and UNESCO, ICOMOS, and 49 Indicator candidate groups had been selected. In the end, we chose 42 attraction indexes in charm of the cultural heritage side, Cultural heritage tourism resources Side, Restraining force Heritage tourism Side three aspects based on the analysis of Importance(M), Standard deviation(SD), Content Validity Ratio(CVR), Agreement, convergence by using Delphi Technique. We can determine these indicators will be useful basic information, for improving the city``s historic attractions. In the future, used these indicators as a basis for Attractions effectiveness evaluation of Gyeongju, Through which the attractions of Gyeongju can be re-recognized.

      • Expression Level of Valosin Containing Protein is Associated with Prognosis of Primary Orbital MALT Lymphoma

        Zhu, Wen-Wen,Kang, Li,Gao, Ya-Ping,Hei, Yan,Dong, Jie,Liu, Yu,Xiao, Li-Hua,Yang, Guang Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

        Objective: To investigate whether the expression level of valosin-containing protein (VCP) is correlated with the prognosis of primary orbital mucosa-associated lymphoid tissue (MALT) lymphoma. Methods: VCP expression in 58 samples from primary orbital MALT lymphoma patients was determined by immunohistochemisty using monoclonal antibodies. Correlations between VCP expression level and prognosis were clarified by statistical analysis. Results: It was found that the percentage of VCP positive cells in samples of primary orbital MALT lymphoma ranged from 32% to 95%. The samples were divided into two groups (level 1 and level 2) according to the median value (45%) of the percentage of VCP positive cells. It was found that the expression level of VCP was significantly correlated with recurrence (P=0.003) and tumor size (P=0.008). At the same time, the 5-year disease-free and overall survival rate of patients of level 1 was significantly better than that of level 2 (P=0.001; P=0.032). There was no observed correlation between the expression level of VCP and other clinical features. Conclusion: VCP could be a useful marker for predicting the prognosis of primary orbital MALT lymphoma.

      • KCI등재

        Protocatechuic Acid, a Gut Bacterial Metabolite of Black Raspberries, Inhibits Adenoma Development and Alters Gut Microbiome Profiles in Apc Min/+ Mice

        Dong Athena,Lin Chien-Wei,Echeveste Carla Elena,Huang Yi-Wen,Oshima Kiyoko,Yearsley Martha,Chen Xiao,Yu Jianhua,Wang Li-Shu 대한암예방학회 2022 Journal of cancer prevention Vol.27 No.1

        Administration of black raspberries (BRBs) and their anthocyanin metabolites, including protocatechuic acid (PCA), has been demonstrated to exert chemopreventive effects against colorectal cancer through alteration of innate immune cell trafficking, modulation of metabolic and inflammatory pathways, etc. Previous research has shown that the gut microbiome is important in the effectiveness of chemoprevention of colorectal cancer. This study aimed to assess the potency of PCA versus BRB dietary administration for colorectal cancer prevention using an ApcMin/+ mouse model and determine how bacterial profiles change in response to PCA and BRBs. A control AIN-76A diet supplemented with 5% BRBs, 500 ppm PCA, or 1,000 ppm PCA was administered to Apc- Min/+ mice. Changes in incidence, polyp number, and polyp size regarding adenomas of the small intestine and colon were assessed after completion of the diet regimen. There were significant decreases in adenoma development by dietary administration of PCA and BRBs in the small intestine and the 5% BRB-supplemented diet in the colon. Pro-inflammatory bacterial profiles were replaced with anti-inflammatory bacteria in all treatments, with the greatest effects in the 5% BRB and 500 ppm PCA-supplemented diets accompanied by decreased COX-2 and prostaglandin E2 levels in colonic mucosa. We further showed that 500 ppm PCA, but not 1,000 ppm PCA, increased IFN-γ and SMAD4 levels in primary cultured human natural killer cells. These results suggest that both BRBs and a lower dose PCA can benefit colorectal cancer patients by inhibiting the growth and proliferation of adenomas and promoting a more favorable gut microbiome condition.

      • SCIESCOPUSKCI등재

        American ginseng significantly reduced the progression of high-fat-diet-enhanced colon carcinogenesis in Apc<sup>Min/+</sup> mice

        Yu, Chunhao,Wen, Xiao-Dong,Zhang, Zhiyu,Zhang, Chun-Feng,Wu, Xiaohui,He, Xin,Liao, Yang,Wu, Ningning,Wang, Chong-Zhi,Du, Wei,He, Tong-Chuan,Yuan, Chun-Su The Korean Society of Ginseng 2015 Journal of Ginseng Research Vol.39 No.3

        Background: Colorectal cancer (CRC) is a leading cause of death worldwide. Chronic gut inflammation is recognized as a risk factor for tumor development, including CRC. American ginseng is a very commonly used ginseng species in the West. Methods: A genetically engineered $Apc^{Min/+}$ mouse model was used in this study. We analyzed the saponin composition of American ginseng used in this project, and evaluated its effects on the progression of high-fat-diet-enhanced CRC carcinogenesis. Results: After oral ginseng administration (10-20 mg/kg/d for up to 32 wk), experimental data showed that, compared with the untreated mice, ginseng very significantly reduced tumor initiation and progression in both the small intestine (including the proximal end, middle end, and distal end) and the colon (all p < 0.01). This tumor number reduction was more obvious in those mice treated with a low dose of ginseng. The tumor multiplicity data were supported by body weight changes and gut tissue histology examinations. In addition, quantitative real-time polymerase chain reaction analysis showed that compared with the untreated group, ginseng very significantly reduced the gene expression of inflammatory cytokines, including interleukin-$1{\alpha}$ (IL-$1{\alpha}$), IL-$1{\beta}$, IL-6, tumor necrosis factor-${\alpha}$, granulocyte-colony stimulating factor, and granulocyte-macrophage colony-stimulating factor in both the small intestine and the colon (all p < 0.01). Conclusion: Further studies are needed to link our observed effects to the actions of the gut microbiome in converting the parent ginsenosides to bioactive ginseng metabolites. Our data suggest that American ginseng may have potential value in CRC chemoprevention.

      • KCI등재

        Comparison of the Effects of Propofol and Midazolam on Inflammation and Oxidase Stress in Children with Congenital Heart Disease Undergoing Cardiac Surgery

        Wen-fang Xia,Qing-shan Zhou,Yu Liu,Qi-zhu Tang,Han-dong Zou 연세대학교의과대학 2011 Yonsei medical journal Vol.52 No.2

        Purpose: To investigate and compare the effects of propofol and midazolam on inflammation and oxidase stress in children with congenital heart disease undergoing cardiac surgery. Materials and Methods: Thirty-two ASA class I-II children with congenital heart disease undergoing cardiac surgery were randomly divided into two groups: propofol combined with low dose fentanyl (PF group, n = 16) and midazolam combined with low dose fentanyl (MF group, n = 16). Tracheal extubation time and length of Intensive Care Unit (ICU) stay were recorded. Blood samples were taken before operation (T_0), at 2 h after release of the aorta cross-clamp (T_3) and at 24 h after operation (T_4) to measure interleukin 6 (IL-6), IL-8, superoxide dismutase (SOD) and malondialdehyde (MDA) levels. Myocardium samples were collected at 10-20 min after aorta cross-clamp (T_1) and at 10-20 min after the release of the aorta cross-clamp (T_2) to detect heme oxygenase-1 (HO-1) expression. Results: Tracheal extubation time and length of ICU stay in PF group were significantly shorter than those of the MF group (p < 0.05, respectively). After cardiopulmonary bypass, IL-6, IL-8 and MDA levels were significantly increased, and the SOD level was significantly reduced in both two groups, but PF group exhibited lower IL-6, IL-8 and MDA levels and higher SOD levels than the MF group (p < 0.05, respectively). The HO-1 expression in the PF group was significantly higher than that in MF group at the corresponding time points (p < 0.05, respectively). Conclusion: Propofol is superior to midazolam in reducing inflammation and oxidase stress and in improving post-operation recovery in children with congenital heart disease undergoing cardiac surgery.

      • Thermus amyloliquefaciens sp. nov., isolated from a hot spring sediment sample.

        Yu, Tian-Tian,Ming, Hong,Yao, Ji-Cheng,Zhou, En-Min,Park, Dong-Jin,Hozzein, Wael N,Kim, Chang-Jin,Wadaan, Mohammed A M,Li, Wen-Jun Society for General Microbiology 2015 International journal of systematic and evolutiona Vol.65 No.8

        <P>A Gram-stain-negative, aerobic bacterium, designated strain YIM 77409T, was isolated from the Niujie hot spring in the Eryuan county of Dali, Yunnan province, south-west China. Cells of the strain were rod-shaped and colonies were yellow and circular. The strain grew at pH?6.0-8.0 (optimum, pH?7.0) and 50-70C (optimum, 60-65C). The predominant menaquinone was MK-8 and the DNA G+C content was 66.4?mol%. Major fatty acids (>10?%) were iso-C15?:?0 and iso-C17?:?0.The polar lipids consisted of one aminophospholipid, one phospholipid and two glycolipids. 16S rRNA gene sequence analysis showed that strain YIM 77409T formed a cluster with Thermus scotoductus DSM 8553T, Thermus antranikianii DSM 12462T, Thermus caliditerrae YIM 77925T and Thermus tengchongensis YIM 77924T, with highest 16S rRNA gene sequence similarity to T. scotoductus DSM 8553T (97.57?%). However, DNA-DNA hybridization indicated that strain YIM 77409T should be viewed as a representative of a novel species, as there was only 30.6??1.6?% reassociation with T. scotoductus DSM 8553T. On the basis of the morphological and chemotaxonomic characteristics, as well as the genotypic data, it is proposed that strain YIM 77409T represents a novel species of the genus Thermus, with the name Thermus amyloliquefaciens sp. nov. The type strain is YIM 77409T (?=?DSM 25898T?=?KCTC 32024T).</P>

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