http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Karthik Paneer Selvam,Taichi Nagahata,Kosuke Kato,Mayuko Koreishi,Toshiyuki Nakamura,Yoshimasa Nakamura,Takeshi Nishikawa,Ayano Satoh,Yasuhiko Hayashi 한국생체재료학회 2020 생체재료학회지 Vol.24 No.4
Background: Conductive sheets of cellulose and carbon nanomaterials and its human skin applications are an interesting research aspect as they have potential for applications for skin compatibility. Hence it is needed to explore the effects and shed light on these applications. Method: To fabricate wearable, portable, flexible, lightweight, inexpensive, and biocompatible composite materials, carbon nanohorns (CNHs) and hydroxyethylcellulose (HEC) were used as precursors to prepare CNH-HEC (Cnh-cel) composite sheets. Cnh-cel sheets were prepared with different loading concentrations of CNHs (10, 20 50,100 mg) in 200 mg cellulose. To fabricate the bio-compatible sheets, a pristine composite of CNHs and HEC was prepared without any pretreatment of the materials. Results: The obtained sheets possess a conductivity of 1.83 × 10− 10 S/m and bio-compatible with human skin. Analysis for skin-compatibility was performed for Cnh-cel sheets by h-CLAT in vitro skin sensitization tests to evaluate the activation of THP-1 cells. It was found that THP-1 cells were not activated by Cnh-cel; hence Cnh-cel is a safe biomaterial for human skin. It was also found that the composite allowed only a maximum loading of 100 mg to retain the consistent geometry of free-standing sheets of < 100 μm thickness. Since CNHs have a unique arrangement of aggregates (dahlia structure), the composite is homogeneous, as verified by transmission electron microscopy (TEM) and, scanning electron microscopy (SEM), and other functional properties investigated by Raman spectroscopy, Fourier transform infrared spectroscopy (FT-IR), conductivity measurement, tensile strength measurement, and skin sensitization. Conclusion: It can be concluded that cellulose and CNHs sheets are conductive and compatible to human skin applications.
( Yusuke Niina ),( Nao Fujimori ),( Taichi Nakamura ),( Hisato Igarashi ),( Takamasa Oono ),( Kazuhiko Nakamura ),( Masaki Kato ),( Robert T. Jensen ),( Tetsuhide Ito ),( Ryoichi Takayanagi ) 대한소화기학회 2012 Gut and Liver Vol.6 No.3
Multiple endocrine neoplasia type 1 (MEN1) is an inherited autosomal dominant disease presenting with pancreatic neuroendocrine tumors (pNETs), parathyroid tumors, or pitu-itary tumors. Using the PubMed database, we reviewed the literature on information regarding the proper diagnosis and treatment of MEN1-associated pNET. Many cases of MEN1-associated pNET are functioning pNETs. Gastrinomas and insulinomas tend to occur frequently in the duodenum and pancreas, respectively. In addition to diagnostic imaging, the selective arterial secretagogue injection test (SASI test) is useful for localizing functioning pNET. The standard treat-ment is surgical resection. However, in the case of a func-tioning pNET, the tumor should first be accurately located using the SASI test before an appropriate surgical method is selected. In cases of a MEN1-associated non-functioning pNET that exceeds 2 cm in diameter, the incidence of distant metastasis is significantly increased, and surgery is recom-mended. In cases of unresectable pNET, a somatostatin analog has been shown to demonstrate antitumor effects and is considered to be a promising treatment. In addition, molecular-targeted drugs have recently been found to be ef-fective in phase III clinical trials. (Gut Liver 2012;6:287-294)
A tendon-driven glove to restore finger function for disabled
Shunji Moromugi,Kousuke Kawakami,Katsutoshi Nakamura,Taichi Sakamoto,Takakazu Ishimatsu 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
An innovative glove system actuated by electric motors has been developed to restore finger functions for disabled people. This glove system is composed of a leather glove having external tendons built-in, an actuation unit and a sensor to detect user"s intentions for finger operations. Fingers are operated by actuation of the thin tendons made of polyethylene. The driving force of the tendon is transferred to the glove from the actuation unit by using bowden cables. It was demonstrated that the glove system can drive user’"s paralyzed fingers. The details of the system and results of the evaluation experiments are reported in this paper.
Impact of Surgery on Oligometastatic Pancreatic Cancer: Current Status and Future Perspectives
Masayuki Sho,Satoshi Yasuda,Minako Nagai,Kota Nakamura,Taichi Terai,Yuichiro Kohara 대한소화기암연구학회 2023 Journal of Digestive Cancer Research (JDCR) Vol.11 No.1
Pancreatic cancer treatment has advanced. In particular, effective chemotherapy regimendevelopment has fundamentally altered the therapeutic concept and strategy for pancreaticcancer treatment. Consequently, the prognosis of patients with pancreatic cancer has graduallyimproved. Conversion surgery for locally advanced pancreatic cancer may offer long-term survival or even a full recovery in some individuals. In contrast, metastatic pancreatic cancer haslong been considered a surgical contraindication because aggressive surgical resection of themetastatic lesions does not prolong patient survival. Unexpectedly positive benefits of anticancer therapy in recent clinical experience were observed even with metastatic pancreatic cancer. To date, little evidence presented the success of surgical resection for metastatic pancreatic cancer treatment in such rare cases. However, hope and concern are growing that surgical intervention, even in patients with metastatic cancer, may result in favorable outcomes. Several studiessuggested different surgical intervention effects depending on metastasis sites and patterns. Thus, this review summarizes the current status of surgery in the multidisciplinary treatment ofoligometastatic pancreatic cancer and discusses future perspectives.