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이승훈,서용칠,구교진,현창택 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1
The purpose of this study is to propose an efficient design-VE job plan and applicable methods in each phase of design process. This is for more effective and practical use of VE in design phase. This study focuses on differences of the VE target selection phase and function analysis phase in each phase of design process. In the phase of preliminary design, conceptual sketch, size, use, or major spaces of project are selected for VE target and function assessment step is skipped because present cost and function cost cannot be produced easily in early in early phase of design. At the end of preliminary design phase, function review phase is added which consists of function satisfactory indices review step and unsatisfactory function removal step.
캐쉬를 이용한 RAID5상에서 작은 쓰기 문제의 성능 분석
최황규,서주하,이승택 江原大學校 産業技術硏究所 1995 産業技術硏究 Vol.15 No.-
In this paper we evaluate the performance of the cached RAID5 which uses the parity cache and the data cache to overcome the small write problem. From the result of the simulation study we show that the cached RAID5 provides performance improvement with reasonable cache size.
조승제,정미라,서국웅,박승범,윤양진,이훈식,강영택 釜山大學校 附設 體育科學硏究所 1998 體育科學硏究所 論文集 Vol.14 No.-
Some authors suggest that certain types of surfaces are the origin of such injuries. A few years after the first medical concerns about surfaces were voiced, publications of biomechanical measurements apperared, describing accleration, force, and impact measurement on different types of surfaces. In many sport activities, surfaces can be under very high dynamic load. This was the reason for the development of various methods for impact simulation, like the development of various methods for impact simulation, like the artificial athlete. Furthermore, it is important to collect information about the hardness of new and already existing surfaces in sport arenas. The idea on which this measuring system is based Is as follows: The stiffness of the material can be computed from the kinematics measurd at touch down of a rigid body onto a material sample. The results show the following The result for the artifical surfaces(Synpave ace) is surprising. It is known that these surfaces are much harder than synpave rebound classic, synpave spring. This finding suggests that it may be possible that the subjective impression is used as one criterion in the selection of landing(or style) strategies. The number of subjects in this experiment is too small to make statistically significant conclusions. It is shown analytically that when an object a deformable surface, the acceleration it experiences is inversely propotional to its mass. In future, it need to stress that the interaction between shoe and surface is important, and this aspect has now become well accepted. Considering biomechanical aspect in player's injury, it request Korean Standards for synthetic playing surfaces in sport like ASTM(America Society for Testing & Materials) standards of America, DIN 18035 standards of Germany, BSI standards of U.K.
Seo, Seongwon,Kim, Jongho,Jang, Geunseok,Kim, Daigeun,Lee, Taek Seung American Chemical Society 2014 ACS APPLIED MATERIALS & INTERFACES Vol.6 No.2
<P>We prepared a water-soluble conjugated polymer composed of electron-donating units and electron-accepting groups in the backbone. The polymer exhibits a short wavelength (blue) emission in aqueous solution and long wavelength (red) emission in the solid state, because of intermolecular energy transfer. Considering this, we develop a new approach for the sensitive detection of trypsin, which is known to control pancreatic exocrine function, using an ensemble system composed of the anionically charged conjugated polymer and cationically charged polypeptides (such as polylysine and polyarginine). The blue-emitting, water-soluble conjugated polymer becomes aggregated upon exposure to the polypeptides, leading to a red-emitting assay ensemble. The red-emitting assay ensemble becomes dissociated in the conjugated polymer and polypeptide fragments by selective degradation of trypsin, which then exhibits recovery of blue emission. This emission-tuning assay ensemble allows for detection of trypsin at nanomolar concentrations, which enables naked-eye detection. Importantly, this strategy can be employed for label-free, continuous assay for trypsin.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2014/aamick.2014.6.issue-2/am405120y/production/images/medium/am-2013-05120y_0008.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/am405120y'>ACS Electronic Supporting Info</A></P>
Seo, Ji-Youn,Jazbinsek, Mojca,Choi, Eun-Young,Lee, Seung-Heon,Yun, Hoseop,Kim, Jong-Taek,Lee, Yoon Sup,Kwon, O-Pil American Chemical Society 2013 Crystal Growth & Design Vol.13 No.3
<P>We report a series of π-conjugated phenyltriene analogous molecules and crystals having different thiolated building blocks, which significantly influence the molecular ordering in the crystalline state. Whereas a polyene crystal having the methylthiolated phenyl (SM) building block exhibits a zigzag molecular ordering based on head-to-tail hydrogen bonds, the crystals of other analogues having the biphenyl sulfane (SB) block exhibit isomorphic crystal structures with herringbone packing. In one of these isomorphic crystals having both SM and SB building blocks, the herringbone packing is accompanied with head-to-tail hydrogen bonds. As a result of such packing promoted by SM and SB building blocks, the rigid phenyltriene bridge shows an unusual twisting and bending conformation, which is accompanied with a significant change of physical properties, such as fluorescent, linear, and nonlinear optical properties in the solid state.</P><P>We report a series of π-conjugated phenyltriene analogous molecules and crystals having different thiolated building blocks. In one of these isomorphic crystals having both methylthiolated phenyl (SM) and biphenyl sulfane (SB) building blocks, the rigid phenyltriene bridge shows an unusual twisting and bending conformation.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/cgdefu/2013/cgdefu.2013.13.issue-3/cg301625d/production/images/medium/cg-2012-01625d_0008.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/cg301625d'>ACS Electronic Supporting Info</A></P>
( Seung-hwan Kwon ),( Shi-xun Ma ),( Yong-hyun Ko ),( Jee-yeon Seo ),( Bo-ram Lee ),( Taek Hwan Lee ),( Sun Yeou Kim ),( Seok-yong Lee ),( Choon-gon Jang ) 한국응용약물학회 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.5
This study was designed to evaluate the pharmacological effects of Vaccinium bracteatum Thunb. methanol extract (VBME) on microglial activation and to identify the underlying mechanisms of action of these effects. The anti-inflammatory properties of VBME were studied using lipopolysaccharide (LPS)-stimulated BV-2 microglial cells. We measured the production of nitric oxide (NO), inducible NO synthase (iNOS), cyclooxygenase (COX)-2, prostaglandin E₂ (PGE₂), tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), and interleukin-6 (IL-6) as inflammatory parameters. We also examined the effect of VBME on intracellular reactive oxygen species (ROS) production and the activity of nuclear factor-kappa B p65 (NF-κB p65). VBME significantly inhibited LPS-induced production of NO and PGE₂ and LPS-mediated upregulation of iNOS and COX-2 expression in a dosedependent manner; importantly, VBME was not cytotoxic. VBME also significantly reduced the generation of the pro-inflammatory cytokines TNF-α, IL-1β, and IL-6. In addition, VBME significantly dampened intracellular ROS production and suppressed NF-κB p65 translocation by blocking IκB- α, phosphorylation and degradation in LPS-stimulated BV2 cells. Our findings indicate that VBME inhibits the production of inflammatory mediators in BV-2 microglial cells by suppressing NF-κB signaling. Thus, VBME may be useful in the treatment of neurodegenerative diseases due to its ability to inhibit inflammatory mediator production in activated BV-2 microglial cells.