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      • SCISCIESCOPUS

        Photonic Crystals: Integration of Colloidal Photonic Crystals toward Miniaturized Spectrometers (Adv. Mater. 9/2010)

        Kim, Shin-Hyun,Park, Hyo Sung,Choi, Jae Hoon,Shim, Jae Won,Yang, Seung-Man WILEY-VCH Verlag 2010 Advanced materials Vol.22 No.9

        <B>Graphic Abstract</B> <P>The cover shows a schematic illustration of patterned colloidal photonic crystals with different bandgap positions. When an unknown light source impinges on the patterned photonic crystals, the light information can be identified from the reflection intensity profile of the constituent photonic crystals. The two optical microscopy images and background image display integrated photonic crystals with 20 different bandgaps spanning the entire visible range, and the SEM image shows the cross-section of the photonic crystal stripes, as reported by Shin-Hyun Kim, Seung-Man Yang, and co-workers on p. 946. <img src='wiley_img_2010/09359648-2010-22-9-ADMA201090022-content.gif' alt='wiley_img_2010/09359648-2010-22-9-ADMA201090022-content'> </P>

      • SCIESCOPUSKCI등재

        Effect of Platelet-Rich Fibrin on Repair of Defect in the Articular Disc in Rabbit Temporomandibular Joint by Platelet-Rich Fibrin

        ( Hyun Su Baek ),( Hye Sung Lee ),( Bok Joo Kim ),( In Kyo Chung ),( Chul Hoon Kim ),( Sun Mi Jin ),( Hie Sung Hwang ),( Sang Hun Shin2 ) 한국조직공학·재생의학회 2011 조직공학과 재생의학 Vol.8 No.6

        The objective of this study was to evaluate platelet-rich fibrin (PRF)’s effectiveness in repairing articular disc defect in the temporomandibular joint (TMJ) of rabbits. Eight rabbits were divided into four groups of two rabbits each, corresponding to groups A, B, C, and D. Both TMJs of all of the rabbits were used in the experiments: the right joints comprised the experimental groups, and the left ones, the control groups. The disc defect was circular and 2 mm in diameter. In the experimental groups, the PRF was compressed into the defect, whereas the control group defects were left untreated. A, B, C, and D groups were sacrificed at the 1st, 2nd, 4th and 6th weeks, respectively. The defects of each control group exhibited no specific changes. Contrastingly, in each experimental group, there was an increased number of chondroblasts at the margins of the defects, along with accelerated cell differentiation and a columnar cell arrangement observable at the time of cell differentiation. The experimental groups showed inflammatory cell infiltrations and fibrosis by the 1st week, maturation of chondrocytes by the 2nd week, and proliferation by the 4th week, after which the defects began to be filled with chondrocytes, a process that was complete after the 6th week. In the histological evaluation (H-E), the experimental groups showed significant increases of chondroblasts after the 2nd and 4th weeks, as well as regular columns of chondrocyte arrays observable during cell division. After 6 weeks, the defects were filled with chondrocytes.

      • Evaluation of Optimum Decapitation Method in Vinyl Mulching Soybean Cultivation

        Sang-Ouk Shin,Hyun-Tae Kim,Ha-Sik Shim,Young-Hoon Lee,Byuong-Won Lee,Chan-Sik Jeong,In-Yoel Baek,Keum-Yong Park 한국작물학회 2010 한국작물학회 학술발표대회 논문집 Vol.2010 No.04

        overgrowth of soybean plants and thereby brings about lodging, decrease in pod number, damage by disease and insect pest, etc. This experiment was carried out to investigate optimum decapitation method in vinyl mulching soybean cultivation. Sinbuseoktae, local soybean variety was sown on May 25 and June 15 in 2009. Decapitation treatments(Non-decapitation, V8 stage-stem, V8 stage-apex, Flowering initiation stage, V8 stage-Stem+Flowering initiation Stage) were practiced on major growth stage on May25 seeding. Lodging did not occur in apex decapitation at V8 stage while other treatments had severe lodging. NAR from R5 to R7 stage was also highest in apex decapitation at V8 stage, which meaned optimum plant organ structure in utilizing light. On the other hand, flowering date and maturity date among treatments were similar. Seed yield in apex decapitation at V8 stage was highest with 274kg/10a, followed by flowering initiation stage with 249kg/10a. The apex decapitation at V8 stage had 26% yield increase as compared with the control of 216kg/10a due to heavy 100-seed weight.

      • SCIESCOPUSKCI등재

        Extent of linkage disequilibrium and effective population size of the Landrace population in Korea

        Shin, Donghyun,Kim, Sung-Hoon,Park, Joowan,Lee, Hak-Kyo,Song, Ki-Duk Asian Australasian Association of Animal Productio 2018 Animal Bioscience Vol.31 No.8

        Objective: The genetic diversity of the Landrace population, a representative maternal pig breed in Korea, is important for genetic improvement. Previously, the effective population size (Ne) has been used to infer the genetic diversity of a population of interest. In this study, we aimed to use single nucleotide polymorphism (SNP) data to characterize linkage disequilibrium (LD) and the Ne of the Korean Landrace population. Methods: We genotyped 1,128 Landrace individuals from three representative Korean major grand-grand-parent (GGP) farms using the Illumina PorcineSNP60 version2 BeadChip, which covers >61,565 SNPs located across all autosomes and mitochondrial and sex chromosomes. We estimated the expected LD and current Ne, as well as ancestral Ne. Results: In the Korean Landrace population, the mean LD ($r^2$) of 3.698 million SNP pairs was $0.135{\pm}0.204$. The mean $r^2$ decreased slowly with as the distance between SNPs increased, and remained constant beyond 3 Mb. According to the $r^2$ calculations, 8,085 of 3.698 million SNP pairs were in complete LD. The current Ne (${\pm}$standard deviation) of the Korean Landrace population is approximately 92.27 [79.46; 105.07] individuals. The ancestral Ne exhibited a slow and steady decline from 186.61 to 92.27 over the past 100 generations. Additionally, we observed more a rapid Ne decrease from the past 20 to 10 generations ago, compared with other intervals. Conclusion: We have presented an overview of LD and the current and ancestral Ne values in the Korean Landrace population. The mean LD and current Ne for the Korean Landrace population confirm the genetic diversity and reflect the history of this pig population in Korea.

      • Detection of Hazardous Gas Using Multidemensional Porous Iron Oxide Nanorods-Decorated Carbon Nanoparticles

        Shin, Dong Hoon,Lee, Jun Seop,Jun, Jaemoon,Kim, Sung Gun,Jang, Jyongsik American Chemical Society 2015 ACS APPLIED MATERIALS & INTERFACES Vol.7 No.3

        <P>Multidimensional porous iron oxide (Fe<SUB>2</SUB>O<SUB>3</SUB>) nanorods-decorated carbon nanoparticles (MPFCNPs) were fabricated using a dual-nozzle electrospray, thermal stirring, and heat treatment. Polypyrrole (PPy) NPs with FeOOH nanorods were synthesized by electrospraying Fe<SUP>3+</SUP> ions, which were adsorbed on the PPy NP surface; the adsorbed Fe<SUP>3+</SUP> ions reacted with NaOH to create FeOOH nuclei, and then followed thermal stirring grow nanorods without aggregation. MPFCNPs were fabricated through heat treatment, with the porous structure created in the Fe<SUB>2</SUB>O<SUB>3</SUB> nanorods by hydroxyl group decomposition. The size of the MPFCNPs and the length of the porous Fe<SUB>2</SUB>O<SUB>3</SUB> nanorods were controlled by the PPy NP template and concentration of initiator solution, respectively. The MPFCNPs were then utilized as a chemical sensor transducer for NO<SUB>2</SUB> gas detection at room temperature. The response of the MFPCNP sensor was highly sensitive, displaying a minimum detectable level of 1 ppm; this detection level is lower than that of organic–inorganic hybrid sensors. Moreover, sensitivity also improved with decreasing the diameter of MPFCNPs and increasing Fe<SUB>2</SUB>O<SUB>3</SUB> nanorod length. The enhanced sensitivity was attributed to the larger surface area presented by the particle size and the porous structure.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2015/aamick.2015.7.issue-3/am507314t/production/images/medium/am-2014-07314t_0010.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/am507314t'>ACS Electronic Supporting Info</A></P>

      • Expression of Hantaan virus G2 envelope protein and its application for vaccine development

        Shin, Young Cheol,Ha, Suk-Hoon,Hong, Sun Pyo,Noh, Kap-Soo,Lee, Sung Hee,Kim, Soo-0k,Yoo, Wang-Don,Kim, Hyun-Su 충남대학교 약학대학 의약품개발연구소 1994 藥學論文集 Vol.10 No.-

        Hantaviruses in Buyavirade family are classified to four major types of viruses which are Hantaan virus, Seoul virus, Pumalla virus, and Prospect Hill virus for their serotypes by plaque reduction neutralization tet(PRNT).

      • SCIESCOPUSKCI등재

        A Comparison Study of Real-Time Solution to All-Attitude Angles of an Aircraft

        Sung-Sik Shin,Jung-Hoon Lee,Sug-Joon Yoon 대한기계학회 2006 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.20 No.3

        In this paper, the quaternion, the dual Euler, and the direction cosine methods are numerically compared using a non-aerodynamic 6 degree-of-freedom rigid model at all-attitude angles of an aircraft. The dual Euler method turns out to be superior to the others in the applications because it shows better numerical accuracy, stability, and robustness in integration step sizes. The dual Euler method is affordable less efficient than the quaternion method in terms of computational cost. Numerical accuracy and stability, which allow larger integration step sizes, are more critical in modern real-time applications than computational efficiency because of today's increased computational power. If the quaternion method is required because of constraints in computation time, then a suppression mechanism should be provided for algebraic constraint errors which eventually add computational burden.

      • Separation of Colloidal Particles by Osmotic Sink Field Flow Fractionation Using UF Hollow Fiber Membranes

        Shin, Se-Jong,Min, Byoung-Ryul,Park, Jin-Won,Ahh, Ik-Sung,Lee, Kang-Taek,Lee, Jae-Hoon The Membrane Society of Korea 2001 Korean Membrane Journal Vol.3 No.1

        Unlike existent field flow fractionation, new method, osmotic sink field flow fractionation is introduced and used ultrafiltration hollow fiber membranes as separation channel. This hollow fiber osmotic sink field flow fractionation is called HF-OSFFF. A theory that describes the retention, relaxation, resolution, plate number for the system, has been developed and experimentally verified by separation model of po1ystyrene latex beads. At external field, it is measured that radial flow rates change according to various concentrations of PEG solutions. Concentration of PEG solution vs. radial flow rate is a linear relation. For diameter distribution of unknown polymer sample, HF-OSFFF compared with the commercial capillary hydrodynamic flow fractionation (CHDF).

      • LT, Others : O-069 ; Single center experience of liver transplantation in patients with portal vein thrombosis

        ( Sang Hyun Song ),( Choon Hyuck David Kwon ),( Jae Won Joh ),( Jong Man Kim ),( Milljae Shin ),( Sung Joo Kim ),( Suk Koo Lee ),( Tae Suk Kim ),( Hyung Hwan Moon ),( Sang Hoon Lee ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1

        Background: Portal vein thrombosis (PVT) is a surgical challenge in liver transplantation (LTx). Presence of PVT was considered as a contraindication for LTx in some centers due to the controversy revolving around the long term outcome of these patients. Therefore, we studied the long term outcome of adult patients with PVT in LTx in a tertiary institution with specialized transplantation unit. Methods: There were 570 cases of adult liver transplantation between 2004 and 2009 in our institution. We excluded 99 cases of deceased donor liver transplantations to facilitate incidence, outcome and surgical management. There were 56 patients with existing PVT before 471 living donor liver transplantations. Patients with PVT were divided into 2 groups according to Yerdal’s classification, mild PVT group (Yerdel group 1 & 2) 43 cases and severe PVT group (Yerdel group 3 & 4) 13 cases. Results: Patients with PVT constituted 11.8% (n=56) in our cohort. When comparing between patients without and with PVT, we did not find statistical difference in terms of age, gender, Child-Pugh score, MELD score & indication for LTx (benign vs malignancy). Rate of PV complication was 3.4% in the non-PVT group and 8.9% in PVT group (p=0.047). Duration of operation and total amount of blood transfusion were also comparable between two groups. The overall survival of PVT group was not significantly different compared to the non-PVT group (p=0.059). Demographics of 43 cases of mild PVT (76.7%) and 13 cases of severe PVT (23.3%) were not different except in severe PVT group had more malignancy cases (27 cases vs 2 cases, p=0.011). The median overall survival of mild PVT group is comparable with non-PVT group (p=0.059) and the median overall survival of severe PVT group is 32 months (1-88) and non-PVT group is 41 months (1-93) (p=0.066). 5-year survival rate of severe PVT is about 60%. Conclusions: Existing PVT prior to liver transplantation does not lead to poorer long term outcome. However in severe cases, we need more careful approach. Therefore, PVT should not be a

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