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Peng Cao,Lan-Ying Liu,Xue-Ting Cai,Xiao-Ning Wang,Jie-Ge Huo,Zhong-Ying Zhou 셀메드 세포교정의약학회 2012 셀메드 (CellMed) Vol.2 No.2
Fever in cancer patients is often due to the following causes: evil qi and toxity stagnancy, disorders of qi and blood, deficiencies of zang and fu organs, and the disorder of yin and yang. The treatments given to cancer patients with a fever are according to five: (a) Excessive inner heat and toxicants: remove heat and the toxicant, induce purgation. We use Cheng-Qi-Tang plus Qing-Wen-Bai-Du-Yin. (b) Tangle of damp and heat, and qi stagnancy: remove damp and heat, smooth the qi channel. We use Gan-Lu-Xiao-Du-Dan or San-Ren-Tang. (c) Obvious blood and heat stagnancy: remove heat and blood stasis. We use Xue-Fu-Zhu-Yu-Tang. (d) Deficiency of spleen qi, inner heat caused by a yin deficiency: nourish spleen qi and yin to remove the inner heat. We use Bu-Zhong-Yi-Qi-Tang or Xiao-Jian-Zhong-Tang. (e) Prominent yin deficiency and hectic fever: replenish yin and remove inner heat. We use Qing-Hao-Bie-Jia-Tang or Chai-Qian-Mei-Lian-San. The pathogenesis of fever in cancer patients is complicated. We can see both deficiency and excess in one differentiation. Therefore, we must make sure of it, then we can get the most effective treatment.
Optimum Power Allocation in a Nonorthogonal Amplify-and-Forward Relay-Assisted Network
Peng Gong,Peng Xue,Daeyoung Park,Duk Kyung Kim IEEE 2011 IEEE TRANSACTIONS ON VEHICULAR TECHNOLOGY Vol.60 No.3
<P>In this paper, we address the problems of power allocation at relays to maximize the transmission rate in a nonorthogonal amplify-and-forward (AF) relay-assisted network, in which multiple relays simultaneously transmit the amplified signals in the same time and frequency. We first formulate a power allocation problem that aims to maximize the minimum of transmission rates in a multicast under a sum power constraint. Then, we prove that the optimal solution can be alternatively obtained by solving its inverse problem, which minimizes the sum power consumption at relays while achieving the target signal-to-noise ratio (SNR) with the same constraint. The inverse problem can be solved by using linear programming, and the inverse problem's complexity can be further reduced by a proposed suboptimal power allocation algorithm. As in the special case of multicast, the optimal solution is derived in unicast, and two suboptimal algorithms are proposed to reduce the feedback overhead and complexity, in which multirelay diversity is also investigated.</P>
Xue Peng,Hu Xiangxiang,Chang Emily,Wang Lufei,Chen Minghui,Wu Tai-Hsien,Lee Dong-Joon,Foster Brian L.,Tseng Henry C.,Ko Ching-Chang 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-
Abnormally increased resorption contributes to bone degenerative diseases such as Paget’s disease of bone (PDB) through unclear mechanisms. Recently, the optineurin (OPTN) gene has been implicated in PDB, and global OPTN knockout mice ( Optn −/− ) were shown to exhibit increased formation of osteoclasts (osteoclastogenesis). Growing evidence, including our own, has demonstrated that intracellular reactive oxygen species (ROS) stimulated by receptor activator of nuclear factor kappa-B ligand (RANKL) can act as signaling molecules to promote osteoclastogenesis. Here, we report that OPTN interacts with nuclear factor erythroid-derived factor 2-related factor 2 (NRF2), the master regulator of the antioxidant response, defining a pathway through which RANKL-induced ROS could be regulated for osteoclastogenesis. In this study, monocytes from Optn −/− and wild-type ( Optn +/+ ) mice were utilized to differentiate into osteoclasts, and both qRT-PCR and tartrate-resistant acid phosphatase (TRAP) staining showed that the Optn −/− monocytes exhibited enhanced osteoclastogenesis compared to the Optn +/+ cells. CellROX ® staining, qRT-PCR, and Western blotting indicated that OPTN deficiency reduced the basal expression of Nrf2 , inhibited the expression of NRF2-responsive antioxidants, and increased basal and RANKL-induced intracellular ROS levels, leading to enhanced osteoclastogenesis. Coimmunoprecipitation (co-IP) showed direct interaction, and immunofluorescence staining showed perinuclear colocalization of the OPTN-NRF2 granular structures during differentiation. Finally, curcumin and the other NRF2 activators attenuated the hyperactive osteoclastogenesis induced by OPTN deficiency. Collectively, our findings reveal a novel OPTN-mediated mechanism for regulating the NRF2-mediated antioxidant response in osteoclasts and extend the therapeutic potential of OPTN in the aging process resulting from ROS-triggered oxidative stress, which is associated with PDB and many other degenerative diseases.
Improved Multi-Cell Joint Channel Estimation for the TD-SCDMA Downlink
XUE, Peng,CAO, Ning,KANG, Dong Kwan,KIM, Duk Kyung The Institute of Electronics, Information and Comm 2009 IEICE TRANSACTIONS ON COMMUNICATIONS - Vol.92 No.4
<P>In this paper, a multi-cell joint channel estimation (JCE) method is proposed for the TD-SCDMA downlink. In the proposed multi-cell JCE approach, the received midambles from adjacent cells are jointly processed, rather than being treated as interference as in single cell channel estimation. By jointly processing all the received midambles, the user can simultaneously estimate the channel impulse responses (CIRs) for both its home cell and adjacent cells. If the received signal from adjacent cells has a delay, multi-cell JCE is still operable with slight adjustment in the midamble matrix, and the performance loss is also minor. The performance of multi-cell JCE is analyzed and evaluated by simulations. The results demonstrate that the proposed multi-cell JCE method can significantly improve the channel estimation accuracy. When the signal from each cell has similar power level, the mean square error (MSE) of the estimated CIRs for all cells is lower than 0.01. With more accurate CIRs from multi-cell JCE, multi-cell JD also yields better performance compared with the single cell channel estimation methods.</P>
Xue-Lin Wang,Peng Liu,Qing Huang,Xue-Feng Xu,Sha Yan 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.56 No.4
This paper reports the basic results obtained from an investigation of the microstructure of lithium niobate (LiNbO3) crystals fabricated by using the focused ion beam (FIB) sputtering method. The morphology characterization of the microstructure is explained in terms of scanning electron microscopy observations based on the geometrical integrity, surface smoothness, cross-sectional area, aspect ratio, etc. The optimized micro-fabrication conditions and the sample morphology characterization are presented, and the sputtering rate of Ga ions for a 30-keV energy milling of the LiNbO3 crystal is calculated, which is lower than the theoretical one gained from “The Stopping and Range of Ions in Matter” (SRIM) sputtering simulation due to the redeposition effect being enhanced with increasing milling depth
Low METTL3 level in midgut of the Bombyx mori inhibit the proliferation of nucleopolyhedrovirus
Xue Peng,Jiangtao Zhai,Zhu Juan,Wang Meixian,Zhao Qiaoling,Huang Jinshan,Tang Shunming,Shen Xingjia 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.1
N6-methyladeosine (m 6 A) plays an important role in virus infection and replication. Bombyx mori nuclear polyhedrosis is caused by Bombyx mori nucleopolyhedrovirus (BmNPV) infection. Expression levels of m 6 Amodification-related genes after the infection of BmNPV were detected at first. Then, expression levels of BmNPV nucleocapsid protein gene VP39 and envelope fusion protein gene GP64 after knockdown of METTL3in vitro were quantified to identify the effect of m 6 A modification on BmNPV. BmNPV firstly infects the larval midgut in case of oral infection. Subsequently, to clarify the relationship between m 6 A modification and resistance of the silkworm to BmNPV, we detected the expression levels of m 6 A-modification-related genes invivo before and after infection of BmNPV. The results indicated that low METTL3 level hindered the proliferation of BmNPV to some extent, and silkworm strain with low METTL3 level showed stronger resistance against BmNPV. This study will accumulate new experimental data for elucidating the resistance mechanism of silkworm against BmNPV.
( Xue Peng ) 고려대학교 법학연구원 2015 The Asian Business Lawyer Vol.15 No.-
Chinese privately owned enterprises (POEs) or “Mainland Private Enterprises (MPEs)” as categorized by the Stock Exchange of Hong Kong have become a significant component of Hong Kong’s capital market, while the research on their corporate governance issues are far from adequate. Meanwhile, among the corporate governance failures occurred to these companies, it is observed that government officials or governmental authorities in the Mainland are involved in many cases. In this connection, this article tries to analyze corporate governance of Chinese POEs listed in Hong Kong from the perspective of their relationship with one of their vital stakeholders . Mainland local governments. In the context of government-business relations in China, it is found that, as a significant stakeholder of Chinese POEs, local governments in China have not only played a central role in the evolvement of China’s private sector, but also have had a major impact on corporate governance practices of Chinese POEs listed on overseas capital market. Indeed, the government-business relation is a double-edged sword to these companies. The lawful participation of controllers in the Mainland local political system may benefit the company in the long run, while too closely enmeshed ties between businesses and governments may pose huge risks to overseas listed POEs. Therefore, in today’s China where the government still plays a key role in the economy and is the final decision maker in many strategically important industries, establishing and maintaining a healthy and sustainable government-business relation is not only indispensable for a Chinese private enterprise to survive in Chinese business environments, but also beneficial to its performance on overseas capital markets.