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Peng Huang,Hong-Zhong Huang,Tudi Huang,Hua-Ming Qian 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.9
A new structural reliability analysis framework is developed to extend the performance of first-order reliability method, which is low robustness and poor accuracy when dealing with highly nonlinear functions. Initially, an improved conjugate sensitivity factor method is proposed to find the most probable point. The method enhances its robustness of convergence by introducing a conjugate gradient direction based sensitivity factor technique and improves its computational efficiency by putting forward a hybrid conjugate gradient factor and an adaptive step length strategy. Subsequently, the dimension reduction-based saddlepoint approximation method is developed, which uses the dimension reduction approach to construct the limit state function as the additive univariate quadratic functions and applies saddlepoint approximation to obtain the result with higher precision. A comparison analysis from five mathematical and structural examples illustrates that the proposed method is better than most existing methods in terms of robustness, efficiency and accuracy for estimating the failure probability of structures.
Breviscapine Ameliorates Fear Extinction and Anxiety in BALB/cJ Mice
Wei Liang(Wei Liang),Jing Huang(Jing Huang),Shuya Yang(Shuya Yang),Peng Huang(Peng Huang),Jun Chen(Jun Chen),Chen Chen(Chen Chen),Qun Yang(Qun Yang),Fengzhan Li(Fengzhan Li) 대한신경정신의학회 2023 PSYCHIATRY INVESTIGATION Vol.20 No.3
Objective In this research, the influence of breviscapine on anxiety, fear elimination, and aggression and the potential mechanism was investigated. Methods Anxiety and locomotion were analyzed by elevated plus maze and open field test in mice. Bussey-Saksida Mouse Touch Screen Chambers were used to perform fear conditioning. Territorial aggression was assessed by resident intruder test. Protein levels were evaluated by Western blot. Breviscapine improved fear-extinction learning in BALB/cJ mice. Results Breviscapine at 20-100 mg/kg increased center cross number, total distance traveled, and velocity in a dose-dependent manner. On the other hand, breviscapine at 20-100 mg/kg decreased the immobility time in open field test. In addition, breviscapine at 20-100 mg/kg increased the ratio of time on the open arm, time on the distal parts of the open arm, and total distance traveled in elevated plus maze. Breviscapine at 100 mg/kg increased the average attack latency and decreased the number of attacks over the last 3 days of resident intruder test. In hippocampus, protein levels of postsynaptic density protein-95 and synaptophysin were elevated by breviscapine at these three doses. Conclusion The administration of breviscapine alleviates fear extinction, anxiety, and aggression, while increases locomotor in a dose-dependent manner, which might be associated with its influence on synaptic function.
Extension of the electrodynamics in the presence of the axion and dark photon
Huang, Fa Peng,Lee, Hye-Sung World Scientific Publishing Company 2019 International Journal of Modern Physics A Vol.34 No.4
<P>We present the extended electrodynamics in the presence of the axion and dark photon. We derive the extended versions of Maxwell’s equations and dark Maxwell’s equations (for both massive and massless dark photons) as well as the wave equations. We discuss the implications of this extended electrodynamics including the enhanced effects in the particle conversions under the external magnetic or dark magnetic field. We also discuss the recently reported anomaly in the redshifted 21 cm spectrum using the extended electrodynamics.</P>
Efficient secret sharing scheme with cheater identification based on QR code
( Peng-cheng Huang ),( Chin-chen Chang ),( Yung-hui Li ),( Yanjun Liu ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.10
Secret sharing is an effective way of protecting secret messages. However, the traditional secret sharing schemes are considered meaningless due to malicious people attention which might raise risks. To overcome the weakness, this paper presents an effective secret sharing scheme with the functionality of cheater identification, based on meaningful QR code. The secret message will be split and concealed in the padding region of cover QR codes with the assistance of Latin square and it can be completely restored when all the involved participants cooperate. The concealing strategy exploits the characteristic of Reed-Solomon (RS) code to ensure the strong robustness of generated QR code pseudo-shares. The meaningful QR code pseudo-shares help to reduce the curious of unrelated persons. Some experiments were done to evaluate the performance of proposed scheme. The results showed that the proposed scheme is feasible, efficient and secure compared to the other existing schemes. It also achieves a higher secret payload and maintains stronger robustness.
Role of miR-511 in the Regulation of OATP1B1 Expression by Free Fatty Acid
Peng, Jin Fu,Liu, Li,Guo, Cheng Xian,Liu, Shi Kun,Chen, Xiao Ping,Huang, Li Hua,Xiang, Hong,Huang, Zhi Jun,Yuan, Hong,Yang, Guo Ping The Korean Society of Applied Pharmacology 2015 Biomolecules & Therapeutics(구 응용약물학회지) Vol.23 No.5
MicroRNAs (miRNAs) are a family of non-coding RNA that are able to adjust the expression of many proteins, including ATP-binding cassette transporter and organic cation transporter. We sought to evaluate the effect of miR-511 on the regulation of OATP1B1 expression by free fatty acids. When using free fatty acids to stimulate Chang liver cells, we found that the expression of miR-511 increased significantly while the expression of OATP1B1 decreased. We also proved that SLCO1B1 is the target gene of miR-511 with a bioinformatics analysis and using the dual luciferase reporter assay. Furthermore, the expressions of SLCO1B1 and OATP1B1 decreased if transfecting Chang liver cells with miR-511, but did not increase when transfecting the inhibitors of miR-511 into steatosis cells. Our study indicates that miR-511 may play an important role in the regulation of OATP1B1 expression by free fatty acids.
Numerical simulation of 3-D probabilistic trajectory of plate-type wind-borne debris
Peng Huang,Feng Wang,Anmin Fu,Ming Gu 한국풍공학회 2016 Wind and Structures, An International Journal (WAS Vol.22 No.1
To address the uncertainty of the flight trajectories caused by the turbulence and gustiness of the wind field over the roof and in the wake of a building, a 3-D probabilistic trajectory model of flat-type wind-borne debris is developed in this study. The core of this methodology is a 6 degree-of-freedom deterministic model, derived from the governing equations of motion of the debris, and a Monte Carlo simulation engine used to account for the uncertainty resulting from vertical and lateral gust wind velocity components. The influence of several parameters, including initial wind speed, time step, gust sampling frequency, number of Monte Carlo simulations, and the extreme gust factor, on the accuracy of the proposed model is examined. For the purpose of validation and calibration, the simulated results from the 3-D probabilistic trajectory model are compared against the available wind tunnel test data. Results show that the maximum relative error between the simulated and wind tunnel test results of the average longitudinal position is about 20%, implying that the probabilistic model provides a reliable and effective means to predict the 3-D flight of the plate-type wind-borne debris.
( Peng Huang ),( Woo Hyoung Kim ) 고려대학교 법학연구원 2010 Korea University Law Review Vol.8 No.-
As two important economies, both China and Korea have been promoting the construction of Free Trade Agreement (FTA), and have made great progress in recent years. Although these two countries have great dependence on foreign trade, their strategies of FTA differ highly because of the difference of economic and trade scales. It`s found that to build the FTA between China and Korea is the focusing of both countries` following strategies. Although the achievement of FTA may cause the uneven distribution of benefits among the domestic industries in these two countries, the negotiations will be launched and successfully completed by making necessary exceptions or transitional arrangements for tariff reduction.
Huang, Peng,Chowdhury, Arindam Gan,Bitsuamlak, Girma,Liu, Roy Techno-Press 2009 Wind and Structures, An International Journal (WAS Vol.12 No.2
The International Hurricane Research Center (IHRC) at Florida International University (FIU) is pursuing research to better understand hurricane-induced effects on residential buildings and other structures through full-scale aerodynamic and destructive testing. The full-scale 6-fan Wall of Wind (WoW) testing apparatus, measuring 4.9 m tall by 7.3 m wide, is capable of generating hurricane-force winds. To achieve windstorm simulation capabilities it is necessary to reproduce mean and turbulence characteristics of hurricane wind flows. Without devices and methods developed to achieve target wind flows, the full-scale WoW simulations were found to be unsatisfactory. To develop such devices and methods efficiently, a small-scale (1:8) model of the WoW was built, for which simulation devices were easier and faster to install and change, and running costs were greatly reduced. The application of such devices, and the use of quasiperiodic fluctuating waveforms to run the WoW fan engines, were found to greatly influence and improve the turbulence characteristics of the 1:8 scale WoW flow. Reasonable reproductions of wind flows with specified characteristics were then achieved by applying to the full-scale WoW the devices and methods found to be effective for the 1:8 scale WoW model.
Experimental study on wind-induced dynamic interference effects between two tall buildings
Huang, Peng,Gu, Ming Techno-Press 2005 Wind and Structures, An International Journal (WAS Vol.8 No.3
Two identical tall building models with square cross-sections are experimentally studied in a wind tunnel with high-frequency-force-balance (HFFB) technique to investigate the interference effects on wind loads and dynamic responses of the interfered building. Another wind tunnel test, in which the interfered model is an aeroelastic one, is also carried out to further study the interference effects. The results from the two kinds of tests are compared with each other. Then the influences of turbulence in oncoming wind on dynamic interference factors are analyzed. At last the artificial neural networks method is used to deal with the experimental data and the along-wind and across-wind dynamic interference factor $IF_{dx}$ & $IF_{dy}$ contour maps are obtained, which could be used as references for wind load codes of buildings.