A framework for structural reliability analysis based on conjugate sensitivity factor and saddlepoint approximation

Peng Huang,Hong-Zhong Huang,Tudi Huang,Hua-Ming Qian 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.9

A new structural reliability analysis framework is developed to extend the performance of first-order reliability method, which is low robustness and poor accuracy when dealing with highly nonlinear functions. Initially, an improved conjugate sensitivity factor method is proposed to find the most probable point. The method enhances its robustness of convergence by introducing a conjugate gradient direction based sensitivity factor technique and improves its computational efficiency by putting forward a hybrid conjugate gradient factor and an adaptive step length strategy. Subsequently, the dimension reduction-based saddlepoint approximation method is developed, which uses the dimension reduction approach to construct the limit state function as the additive univariate quadratic functions and applies saddlepoint approximation to obtain the result with higher precision. A comparison analysis from five mathematical and structural examples illustrates that the proposed method is better than most existing methods in terms of robustness, efficiency and accuracy for estimating the failure probability of structures.

Breviscapine Ameliorates Fear Extinction and Anxiety in BALB/cJ Mice

Wei Liang(Wei Liang),Jing Huang(Jing Huang),Shuya Yang(Shuya Yang),Peng Huang(Peng Huang),Jun Chen(Jun Chen),Chen Chen(Chen Chen),Qun Yang(Qun Yang),Fengzhan Li(Fengzhan Li) 대한신경정신의학회 2023 PSYCHIATRY INVESTIGATION Vol.20 No.3

Objective In this research, the influence of breviscapine on anxiety, fear elimination, and aggression and the potential mechanism was investigated. Methods Anxiety and locomotion were analyzed by elevated plus maze and open field test in mice. Bussey-Saksida Mouse Touch Screen Chambers were used to perform fear conditioning. Territorial aggression was assessed by resident intruder test. Protein levels were evaluated by Western blot. Breviscapine improved fear-extinction learning in BALB/cJ mice. Results Breviscapine at 20-100 mg/kg increased center cross number, total distance traveled, and velocity in a dose-dependent manner. On the other hand, breviscapine at 20-100 mg/kg decreased the immobility time in open field test. In addition, breviscapine at 20-100 mg/kg increased the ratio of time on the open arm, time on the distal parts of the open arm, and total distance traveled in elevated plus maze. Breviscapine at 100 mg/kg increased the average attack latency and decreased the number of attacks over the last 3 days of resident intruder test. In hippocampus, protein levels of postsynaptic density protein-95 and synaptophysin were elevated by breviscapine at these three doses. Conclusion The administration of breviscapine alleviates fear extinction, anxiety, and aggression, while increases locomotor in a dose-dependent manner, which might be associated with its influence on synaptic function.

Role of miR-511 in the Regulation of OATP1B1 Expression by Free Fatty Acid

Peng, Jin Fu,Liu, Li,Guo, Cheng Xian,Liu, Shi Kun,Chen, Xiao Ping,Huang, Li Hua,Xiang, Hong,Huang, Zhi Jun,Yuan, Hong,Yang, Guo Ping The Korean Society of Applied Pharmacology 2015 Biomolecules & Therapeutics(구 응용약물학회지) Vol.23 No.5

MicroRNAs (miRNAs) are a family of non-coding RNA that are able to adjust the expression of many proteins, including ATP-binding cassette transporter and organic cation transporter. We sought to evaluate the effect of miR-511 on the regulation of OATP1B1 expression by free fatty acids. When using free fatty acids to stimulate Chang liver cells, we found that the expression of miR-511 increased significantly while the expression of OATP1B1 decreased. We also proved that SLCO1B1 is the target gene of miR-511 with a bioinformatics analysis and using the dual luciferase reporter assay. Furthermore, the expressions of SLCO1B1 and OATP1B1 decreased if transfecting Chang liver cells with miR-511, but did not increase when transfecting the inhibitors of miR-511 into steatosis cells. Our study indicates that miR-511 may play an important role in the regulation of OATP1B1 expression by free fatty acids.

Numerical simulation of 3-D probabilistic trajectory of plate-type wind-borne debris

Peng Huang,Feng Wang,Anmin Fu,Ming Gu 한국풍공학회 2016 Wind and Structures, An International Journal (WAS Vol.22 No.1

To address the uncertainty of the flight trajectories caused by the turbulence and gustiness of the wind field over the roof and in the wake of a building, a 3-D probabilistic trajectory model of flat-type wind-borne debris is developed in this study. The core of this methodology is a 6 degree-of-freedom deterministic model, derived from the governing equations of motion of the debris, and a Monte Carlo simulation engine used to account for the uncertainty resulting from vertical and lateral gust wind velocity components. The influence of several parameters, including initial wind speed, time step, gust sampling frequency, number of Monte Carlo simulations, and the extreme gust factor, on the accuracy of the proposed model is examined. For the purpose of validation and calibration, the simulated results from the 3-D probabilistic trajectory model are compared against the available wind tunnel test data. Results show that the maximum relative error between the simulated and wind tunnel test results of the average longitudinal position is about 20%, implying that the probabilistic model provides a reliable and effective means to predict the 3-D flight of the plate-type wind-borne debris.

Vietnamese Brides’ Practices of Maternal Citizenship at the China-Vietnam Border

Pengli Huang,Sik Ying Ho 숙명여자대학교 아시아여성연구원 2016 Asian Women Vol.32 No.1

This paper shows how Vietnamese brides create new transnational subjectivities through practicing maternal citizenship at the China-Vietnam border. It focuses on discussing different strategies they have adopted in their daily lives: 1) blurring the boundaries between house-keeper and breadwinner; 2) developing dual belonging; 3) establishing transnational maternal alliances; and 4) neutralizing ethnicity/nationality differences. The authors argue that through forming a ‘‘creolized’’ culture, Vietnamese brides have engaged in a conscious attempt to master both Chinese and Vietnamese elements in their making of a new transnational identity. The China-Vietnam border not only provides a favorable context for the development of personal relationships, but these relationships are also an attractive strategy for gaining a social foothold in the more and more globalized world, whether they are in a cosmopolitan center or cosmopolitan periphery.

Efficient secret sharing scheme with cheater identification based on QR code

( Peng-cheng Huang ),( Chin-chen Chang ),( Yung-hui Li ),( Yanjun Liu ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.10

Secret sharing is an effective way of protecting secret messages. However, the traditional secret sharing schemes are considered meaningless due to malicious people attention which might raise risks. To overcome the weakness, this paper presents an effective secret sharing scheme with the functionality of cheater identification, based on meaningful QR code. The secret message will be split and concealed in the padding region of cover QR codes with the assistance of Latin square and it can be completely restored when all the involved participants cooperate. The concealing strategy exploits the characteristic of Reed-Solomon (RS) code to ensure the strong robustness of generated QR code pseudo-shares. The meaningful QR code pseudo-shares help to reduce the curious of unrelated persons. Some experiments were done to evaluate the performance of proposed scheme. The results showed that the proposed scheme is feasible, efficient and secure compared to the other existing schemes. It also achieves a higher secret payload and maintains stronger robustness.

Extension of the electrodynamics in the presence of the axion and dark photon

Huang, Fa Peng,Lee, Hye-Sung World Scientific Publishing Company 2019 International Journal of Modern Physics A Vol.34 No.4

<P>We present the extended electrodynamics in the presence of the axion and dark photon. We derive the extended versions of Maxwell’s equations and dark Maxwell’s equations (for both massive and massless dark photons) as well as the wave equations. We discuss the implications of this extended electrodynamics including the enhanced effects in the particle conversions under the external magnetic or dark magnetic field. We also discuss the recently reported anomaly in the redshifted 21 cm spectrum using the extended electrodynamics.</P>

Probing the baryogenesis and dark matter relaxed in phase transition by gravitational waves and colliders

Huang, Fa Peng,Li, Chong Sheng American Physical Society 2017 Physical review. D Vol.96 No.9

<P>The cosmological phase transition with Q-balls production mechanism can explain the baryogenesis and dark matter simultaneously, where constraints on dark matter masses and reverse dilution are significantly relaxed. We study how to probe this scenario by collider signals at QCD next-to-leading order and gravitational wave signals.</P>

High-Performance Bottom-Contact Organic Thin-Film Transistors Based on Benzo[<i>d</i>,<i>d</i>′]thieno[3,2-<i>b</i>;4,5-<i>b</i>′]dithiophenes (BTDTs) Derivatives

Huang, Peng-Yi,Chen, Liang-Hsiang,Kim, Choongik,Chang, Hsiu-Chieh,Liang, You-jhih,Feng, Chieh-Yuan,Yeh, Chia-Ming,Ho, Jia-Chong,Lee, Cheng-Chung,Chen, Ming-Chou American Chemical Society 2012 ACS APPLIED MATERIALS & INTERFACES Vol.4 No.12

<P>Three benzo[<I>d</I>,<I>d</I>′]thieno[3,2-<I>b</I>;4,5-<I>b</I>′]dithiophene (<B>BTDT</B>) derivatives, end-functionalized with benzothiophenyl (<B>BT-BTDT</B>; <B>2</B>), benzothieno[3,2-b]thiophenyl (<B>BTT-BTDT</B>; 3), and benzo[<I>d</I>,<I>d</I>′]thieno[3,2-<I>b</I>;4,5-<I>b</I>′]dithiophenyl (<B>BBTDT</B>; <B>4</B>), were prepared for bottom-contact/bottom-gate organic thin-film transistors (OTFTs). An improved one-pot [2 + 1 + 1] synthetic method of <B>BTDT</B> with improved synthetic yield was achieved, which enabled the efficient realization of new <B>BTDT</B>-based semiconductors. All of the <B>BTDT</B> compounds exhibited high performance p-channel characteristics with carrier mobilities as high as 0.34 cm<SUP>2</SUP>/(V s) and a current on/off ratio of 1 × 10<SUP>7</SUP>, as well as enhanced ambient stability. The device characteristics have been correlated with the film morphologies and microstructures of the corresponding compounds.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2012/aamick.2012.4.issue-12/am3022448/production/images/medium/am-2012-022448_0010.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/am3022448'>ACS Electronic Supporting Info</A></P>

Experimental study and FE analysis of tile roofs under simulated strong wind impact

Huang, Peng,Lin, Huatan,Hu, Feng,Gu, Ming Techno-Press 2018 Wind and Structures, An International Journal (WAS Vol.26 No.2

A large number of low-rise buildings experienced serious roof covering failures under strong wind while few suffered structural damage. Clay and concrete tiles are two main kinds of roof covering. For the tile roof system, few researches were carried out based on Finite Element (FE) analysis due to the difficulty in the simulation of the interface between the tiles and the roof sheathing (the bonding materials, foam or mortar). In this paper, the FE analysis of a single clay or concrete tile with foam-set or mortar-set were built with the interface simulated by the equivalent nonlinear springs based on the mechanical uplift and displacement tests, and they were expanded into the whole roof. A detailed wind tunnel test was carried out at Tongji University to acquire the wind loads on these two kinds of roof tiles, and then the test data were fed into the FE analysis. For the purpose of validation and calibration, the results of FE analysis were compared with the full-scale performance ofthe tile roofs under simulated strong wind impact through one-of-a-kind Wall of Wind (WoW) apparatus at Florida International University. The results are consistent with the WoW test that the roof of concrete tiles with mortar-set provided the highest resistance, and the material defects or improper construction practices are the key factors to induce the roof tiles' failure. Meanwhile, the staggered setting of concrete tiles would help develop an interlocking mechanism between the tiles and increase their resistance.