A New Pattern of Technology Transfer in Rural China: Triple Helix of Academy-agriculture-government Relations in Baoji City

( Jun Tu ),( Shulin Gu ),( Guisheng Wu ) 기술경영경제학회 2005 Journal of Technology Innovation Vol.13 No.2

During the transformation of the agro-technology extension system in rural China, many new policy experiments are emerging to rebuild the lost linkages and to improve technology transfer with the system and among systems. Applying the Triple Helix Model of academy-agriculture-government relations, this paper explores a new pattern of technology transfer with the case of BaojiCity. The authors interpret the mechanism of "Courtyards for Agro-experts", as well as the comparison between different types of courtyards. This article concludes that the Triple Helix in the agro-sector improves technology transfer and accelerates knowledge-based regional development. In the interest of farmers there should also be concern over reducing inequity during the reform.

A New Pattern of Technology Transfer in Rural China: Triple Helix of Academy-agriculture-government Relations in Baoji City

Tu, Jun,Gu, Shulin,Wu, Guisheung The Korean Society for Technology Manageme and Eco 2005 Journal of Technology Innovation Vol.13 No.2

During the transformation of the agro-technology extension in rural China, many new Policy experiments are emerging to rebuild the lost linkages and to improve technology transfer with the system and among systems. Applying the Triple Helix Model of academy-agriculture-government relations, this paper explores a new pattern of technology transfer with the case of BaojiCity. The authors interpret the mechanism of 'Courtyards for Agro-experts', as well as the comparison between different types of courtyards. This article concludes that the Triple Helix in the agro-sector improves technology transfer and accelerates knowledge-based regional development. In the interest of farmers there should also be concern over reducing inequity the reform.

ORESARA15 Acts Synergistically with ANGUSTIFOLIA3 and Separately from AINTEGUMENTA to Promote Cell Proliferation during Leaf Growth

Jun, Sang Eun,Kim, Jin Hee,Hwang, Ji Young,Huynh Le, Thien Tu,Kim, Gyung-Tae MDPI AG 2020 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.21 No.1

<P>Developing leaves undergo sequential coordinated cell proliferation and cell expansion to determine their final size and shape. Although several important regulators of cell proliferation have been reported, the gene network regulating leaf developmental processes remains unclear. Previously, we showed that ORESARA15 (ORE15) positively regulates the rate and duration of cell proliferation by promoting the expression of direct targets, GROWTH-REGULATING FACTOR (GRF) transcription factors, during leaf growth. In the current study, we examined the spatiotemporal patterns of ORE15 expression and determined that ORE15 expression partially overlapped with AN3/GIF1 and ANT expression along the midvein in the proximal region of the leaf blade in young leaves. Genetic analysis revealed that ORE15 may function synergistically with AN3 to control leaf growth as a positive regulator of cell proliferation. Our molecular and genetic studies are the first to suggest the importance of functional redundancies between ORE15 and AN3, and between AN3 and ANT in cell proliferation regulatory pathway during leaf growth.</P>

The Effect of H2O2/Fe2+ Catalytic Oxidation System on the Morphology, Structure and Properties of Flake-Like Poly(2,3-dimethylaniline)

Jun Yan,Li Ma,Mengyu Gan,Xiao Li,Zhitao Li,Jihai Tang,Ying Tu,Haifeng Hu 한국고분자학회 2014 Macromolecular Research Vol.22 No.8

In this work, flake-like poly(2,3-dimethylaniline) (P(2,3-DMA)) with enhanced thermal stability andanticorrosive ability was synthesized by in situ polymerization using H2O2/Fe2+ catalytic oxidation system, comparingwith traditional oxidant ammonium persulfate (APS) synthetic method. The structure and morphology of thesamples were characterized Fourier transform infrared (FTIR) spectra, X-ray diffraction (XRD) and field-emissionscanning electron microscope (FESEM). The experimental results demonstrated that using H2O2/Fe2+ catalytic oxidationsystem was more inclined to form the two-dimensional P(2,3-DMA) flakes. The enhancement in thermostabilityand corrosion resistance was attributed to the formation of phenazine-like structures in the polymer chains,which could serve as templates to form the flake-like morphology. In addition, using H2O2/Fe2+ catalytic oxidationsystem is more environmental friendly than the APS method that can avoid ammonium pollution on aquatic life aswell as waters.

Research on Stratified Multi-objective Optimization Algorithm in Wireless Networks

Tu Xionggang,Chen Jun,Zhang Changjiang 보안공학연구지원센터 2015 International Journal of Future Generation Communi Vol.8 No.4

Due to the cost, reliability and quality of communication equilibrium of the traditional FM radio network optimization algorithms during the construction , hierarchical multi-objective optimization algorithm is put forth.First, increasee FM wireless networks mobile node and select new-adding link waypoints’ optimal vector set, then design a hierarchical optimization model, and then use hierarchical multi-objective optimization algorithm to solve the problems of VHF wireless networks.Finally, compared simulation experiment of stratified multi-objective optimization algorithm and Glid algorithm and violent search algorithm is conducted, and the experiment shows that: stratified multi-objective optimization algorithm is smaller than traditional optimization algorithms in areas such in the network nodes, the average communication jump and the average attenuation of communication after running 50 times, i.e. lower cost, better network reliability and communication quality.

Role for SUMOylation in Disturbed Flow-induced Atherosclerotic Plaque Formation

Jun-ichi Abe,Nhat-Tu Le,허경선 대한의용생체공학회 2015 Biomedical Engineering Letters (BMEL) Vol.5 No.3

Although atherosclerosis is a multi-factorial disease, thefocalization of atherosclerotic plaques on the vessel wallsuggests that local factors such as patterns of local bloodflow are critical in the progression of atherosclerosis. Bloodflow creates various types of forces onto the surface ofvascular endothelial cells (ECs). Among those various typesof forces, fluid shear stress has a major influence on thestructure and function of ECs. At the branch points and thelesser curvature of the aortic arch, blood flow is disturbed (dflow)and atherosclerotic plaques are frequently detected. Atthe straight parts of the arterial tree and the greater curvatureof aortic arch, blood flow is steady (s-flow, high shear stress)and atherosclerotic plaques are rare. These two patterns ofblood flow (d-flow and s-flow) affects EC structure andfunction differently. However, molecular mechanisms underlinethe difference remains unclear. To provide insights into thisquestion, studies have suggested a number of theories withmultiple proposed signaling pathways, and the role ofpost-translational modifications has emerged. Particularly,SUMOylation is highlighted based on its potentiality toregulate a wide range of cellular functions. EC dysfunctioninduced by SUMOylation is proposed to accelerate d-flowinducedatherosclerosis. In this review, we focus onSUMOylation and its role in regulating transcriptional networksand propose a mechanistic link between d-flow and ECdysfunction. Since a strong correlation exists between d-flowand atherosclerotic plaque formation, understanding themechanism of d-flow-induced SUMOylation events mayreveal new paths towards therapeutic interventions againstEC dysfunction and atherosclerosis.

Survivin Gene Functions and Relationships between Expression and Prognosis in Patients with Nasopharyngeal Carcinoma

Cai, Jun-Hong,Fu, Sheng-Miao,Tu, Zhi-Hua,Deng, Li-Qun,Liang, Zhu,Chen, Xin-Ping,Gong, Xuan-Ju,Wan, Li-Hua Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.6

This study aimed to investigate the relationship between prognosis and protein and mRNA expression of an apoptotic inhibitor gene, survivin, in patients with nasopharyngeal carcinoma. Furthermore, functions of the survivin gene in the CNE2 nasopharyngeal carcinoma cell line were assessed. Immunohistochemistry and in situ hybridization were used in detecting the survivin protein and mRNA in 44 nasopharyngeal carcinoma specimens, and 30 chronic nasopharyngitis samples as controls. Survivin gene expression in CNE2 cell line was suppressed with an shRNA (short hairpin RNA). The positive ratios of expression for survivin protein and mRNA in nasopharyngeal carcinoma were 79.5% and 75.0% respectively, obviously higher than in the control group (p<0.01), and there is very good consistency between the two methods. The mean survival time of patients with higher survivin protein or mRNA expression was shorter than in patients with lower levelsv(p<0.01). Proliferation of the CNE2 cell line was distinctly inhibited by the shRNA. The results indicate that overexpression of the survivin gene plays an important role in onset and development of nasopharyngeal carcinoma, and it may be helpful for prognostic appraisal.

Current Perspectives on the Effects of Plant Growth-promoting Rhizobacteria

Thien Tu Huynh Le(후인르티엔투),Sang Eun Jun(전상은),Gyung-Tae Kim(김경태) 한국생명과학회 2019 생명과학회지 Vol.29 No.11

근권은 식물 뿌리와 토양 미생물이 서로의 신호를 주고 받으며 끊임없이 상호반응하는 역동적인 장소이다. 근권 주위에서 식물의 생장과 생산성에 유익한 토양 미생물을 식물생장촉진근권미생물(Plant Growth Promoting Rhizobacteria, PGPR)이라 칭하며, 이 PGPR은 식물 전 생장기간동안 생물학적 및 비생물학적 스트레스에 대한 저항성, 식물 호르몬 조절, 영양분의 흡수와 이용 등에 영향을 끼침으로써 식물의 생장과 발달, 면역, 생산력 등중요한 생명 과정에 관여한다. 그리고, PGPR은 식물 생장을 유도하는 2차 대사산물이나 휘발성 유기 화합물을 생산하고, 식물의 뿌리 역시 식물 유해한 인자 혹은 병원성 인자에 대항하여 자신을 보호하거나 토양 성질 개선을 위해, PGPR을 유인하고 정착시키기 위한 물질을 생산, 분비한다. 그러므로, 식물과 PGPR 사이의 상호작용은 필수적이면서도 상호의존적이다. 현재까지, PGPR에 대한 많은 연구는 직간접적 개념에 대하여 공통적 또는 다양한 조건들에서 여러 방식으로 PGPR의 기능을 밝히는 방향으로 전개되어 왔다. 본 총설에서는 세포분열과 팽창, 분화에 의한 식물의 생장과 발달의 촉진, 식물생장조절인자와 호르몬의 유도, 영양물질의 고정, 용해, 무기화를 촉진하기 위한 PGPR의 역할과 전략을 소개하였다. 또한 PGPR와 토양 미생물군의 효과에 대한 현재까지의 연구 정보를 요약하였다. The rhizosphere is the active zone where plant roots communicate with the soil microbiome, each responding to the other’s signals. The soil microbiome within the rhizosphere that is beneficial to plant growth and productivity is known as plant growth-promoting rhizobacteria (PGPR). PGPR take part in many pivotal plant processes, including plant growth, development, immunity, and productivity, by influencing acquisition and utilization of nutrient molecules, regulation of phytohormone biosynthesis, signaling, and response, and resistance to biotic- and abiotic-stresses. PGPR also produce secondary compounds and volatile organic compounds (VOCs) that elicit plant growth. Moreover, plant roots exude attractants that cause PGPR to aggregate in the rhizosphere zone for colonization, improving soil properties and protecting plants against pathogenic factors. The interactions between PGPR and plant roots in rhizosphere are essential and interdependent. Many studies have reported that PGPR function in multiple ways under the same or diverse conditions, directly and indirectly. This review focuses on the roles and strategies of PGPR in enhancing nutrient acquisition by nutrient fixation/solubilization/mineralization, inducing plant growth regulators/phytohormones, and promoting growth and development of root and shoot by affecting cell division, elongation, and differentiation. We also summarize the current knowledge of the effects of PGPR and the soil microbiota on plants.

G-protein Coupled Estrogen Receptor 1 Expression in Primary Breast Cancers and Its Correlation with Clinicopathological Variables

Hao-jun Luo,Ping Luo,Guang-lun Yang,Qiong-le Peng,Man-ran Liu,Gang Tu 한국유방암학회 2011 Journal of breast cancer Vol.14 No.3

Purpose: G-protein coupled estrogen receptor 1 (GPER) probably play important roles in the progression of breast cancer including endocrine therapeutic resistance. We evaluated GPER in primary breast cancers. Methods: Immunohistochemistry was used to detect GPER in paraffin-embedded tissues of primary breast cancers from 423 patients and GPER expression was correlated with clinicopathological factors. Results: GPER was expressed in 63.8% of specimens, coexpressed with estrogen receptor alpha (ERα) in 36.6% of tumors and was positive in 62.5% of the ERα-negative tumors. The expression of GPER had no relationship with the status of ERα, progesterone receptor and HER2. Although the expression of GPER was significantly inversely related with nodal status (p=0.045), no correlation between GPER expression and other clinicopathological variables (age, menstruation status, tumor size, stage, histologic grade, Nottingham Prognostic Index or pathological type) was found. Conclusion: GPER and ERα exhibited independent expression pattern of distribution in primary breast cancers. A long-term follow-up and a more definite molecular phenotype for ER are necessary in confirming studies.

U-phosphate biomineralization induced by Bacillus sp. dw-2 in the presence of organic acids

Hong Tu,Guoyuan Yuan,Changsong Zhao,Jun Liu,Feize Li,Jijun Yang,Jiali Liao,Yuanyou Yang,Ning Liu 한국원자력학회 2019 Nuclear Engineering and Technology Vol.51 No.5

In this paper, we systematically investigated the influence of some selected ligands on the U-phosphateprecipitation induced by soil bacteria. These organics are widely ranging from acetate, lactate, salicylateand citrate to oxalate. The results revealed that uranium could be biomineralized on bacteria asUO2HPO4$4H2O or (UO2)3(PO4)2$4H2O. The influence of organic ligands on the biomineralization hadclear-cut correlations with its complexation abilities to uranyl. It was clearly found that the U-phosphatebiomineralization was affected noticeably by the strong ligands (oxalate and citrate). Further studydiscovered that when the organic ligands were uncompetitive with biotic PO4 3 for uranyl, the transformationof uranyl species from b-UO2(OH)2 colloidal particles to free UO2 2 þ-ligands ions could facilitatethe U-phosphate biomineralization. However, when the organic ligands competed with biotic PO4 3 foruranyl, the U-phosphate biomineralization were inhibited. Our results highlight the importance ofcomplex interactions of strong organic ligands with uranyl during the bacterial precipitation of UePcompounds and thus for the mobilization and immobilization of radio-nuclides in the nature.