Microbial Colonization at Early Life Promotes the Development of Diet-Induced CD8αβ Intraepithelial T Cells

Jung, Jisun,Surh, Charles D.,Lee, You Jeong Korean Society for Molecular and Cellular Biology 2019 Molecules and cells Vol.42 No.4

Intraepithelial lymphocytes (IELs) develop through the continuous interaction with intestinal antigens such as commensal microbiome and diet. However, their respective roles and mutual interactions in the development of IELs are largely unknown. Here, we showed that dietary antigens regulate the development of the majority of $CD8{\alpha}{\beta}$ IELs in the small intestine and the absence of commensal microbiota particularly during the weaning period, delay the development of IELs. When we tested specific dietary components, such as wheat or combined corn, soybean and yeast, they were dependent on commensal bacteria for the timely development of diet-induced $CD8{\alpha}{\beta}$ IELs. In addition, supplementation of intestinal antigens later in life was inefficient for the full induction of $CD8{\alpha}{\beta}$ IELs. Overall, our findings suggest that early exposure to commensal bacteria is important for the proper development of dietary antigen-dependent immune repertoire in the gut.

담도폐쇄증의 수술 후 영상 소견

Jisun Hwang,Hee Mang Yoon,Pyeong Hwa Kim,Jung-Man Namgoong,Seak Hee Oh,Ah Young Jung,Jin Seong Lee,Young Ah Cho 대한영상의학회 2022 대한영상의학회지 Vol.83 No.5

The Kasai portoenterostomy is the first-line treatment for the restoration of the flow of bile to the small intestine in patients with biliary atresia. Various complications can occur after Kasai portoenterostomy, including ascending cholangitis, biliary cirrhosis, and portal hypertension. Of these potential complications, ascending cholangitis in the most common. In cases of patients having uncontrolled complications due to progressive liver cirrhosis, portal hypertension, or progressive hyperbilirubinemia, liver transplantation is the indicated as treatment plan. Lifelong follow-up, particularly involving imaging studies, is important for the identification of various complications arising from biliary atresia after Kasai portoenterostomy. Additionally, imaging studies play a crucial role in the evaluation of potential liver donors and recipients. US is a key imaging modality utilized in the management of patients who undergo Kasai portoenterostomy, while CT and MRI are imperative to obtaining an accurate diagnosis.

스마트 그리드를 위한 IEEE 802.11s 기반 무선 메쉬 네트워크

정지선(JiSun Jung),김재범(Jae-Beom Kim),고영배(Young-Bae ko),이상엽(Sang-Youm Lee) 한국통신학회 2010 韓國通信學會論文誌 Vol.35 No.9

학습자 중심 교육에서의 좋은 학교의 의미 탐색

정지선(Jung, Jisun),권동택(Kwon, Dongtaik) 학습자중심교과교육학회 2016 학습자중심교과교육연구 Vol.16 No.10

학교는 오늘날 교육의 많은 부분을 담당하고 있는 공적 기관으로서 그 역할의 중요성이 커지고 있다. 이에 본 연구는 사회 구성원들의 요구와 바람을 반영하고 학교교육의 대상인 학습자의 만족을 이끌어낼 수 있는 좋은 학교의 의미를 탐색하고자 좋은 학교의 특성 요인들을 살펴본 후 학교 수준, 교실 수준, 학생 수준으로 구분하여 정리하였다. 학습자 중심 교육을 위한 좋은 학교는 합리적 의사소통에 기반한 학교 목표 수립과 공유, 목표에 기반한 교육과정의 수립, 학교 구성원간의 신뢰로운 관 계 형성, 교직원들의 지속적인 자기개발, 질서와 규율이 있는 안전한 학교 풍토, 학부모의 긍정적 학교 참여와 같은 학교 수준의 특성 요인을 필요로 한다. 교실 수준에서는 학생의 성취에 대한 높은 기대, 교사의 효율적 교수 전략, 학습에 집중하게 하 는 매력적인 학습 환경, 학생 진보에 대한 신중한 평가와 모니터링이 중요한 요인이다. 마지막으로 학생 수준에서는 활동적인 참여와 책임감 공유를 통한 높은 자아개념 형성, 학생의 권리와 책무 강조, 자율적 학습의 격려, 과제를 학습할 충분한 기회 와 시간, 기본 기능 획득에 대한 강조를 특성요인으로 도출하였다. 마지막으로 이러한 좋은 학교의 특성 요인을 바탕으로 좋은 학교의 의미와 성격을 정리하였다. The school is a public institution in charge of a large part of today’s education and the importance of it’s role is growing. This study explored the meaning of good school that can reflect the needs and wishes of members of society and get learners’ satisfaction and arranged the characteristic factors of good school by separate school level, classroom level, student level. The good school for the learner-centered education needs the school level factors such as establishment of the school goals based on reasonable communication and sharing, establishment of the curriculum based on the goals, formation of reliable relationship between school staffs, continued self-development of school staffs, safe and orderly school climate, positive parental involvement in school. There are the classroom level factors such as a high level of expectation for student achievement, effective teaching strategies, attractive learning environment that is focused on learning, careful evaluation and monitoring about student progress. Finally, the student level factors such as a high self-concept that was formed through active participation and shared responsibility, emphasis of student’s right and responsibility, encouragement of autonomous learning, sufficient opportunities and times that learn tasks, emphasis on acquirement of basic skills were derived. Finally, the meaning and nature of the good school based on the characteristics of the good school were reified.

High Density of Line Pattern by Using De-Wetting During Soft-Lithography.

Lee, Jisun,Lee, Su Kyoung,Jung, Jin-Mi,Jung, Hee-Tae American Scientific Publishers 2015 Journal of Nanoscience and Nanotechnology Vol.15 No.2

<P>Here we prepared highly reliable and high density of pattern by using de-wetting induced soft-lithography. Additional line pattern arising from de-wetting of PS is generated in the protrusion of poly-dimethyl-siloxane (PDMS) mold by controlling thermal annealing time and molecular weight of PS. We found that such de-wetting and pattern formation is not dependent on the PS film thickness, but strongly influenced by molecular weight and annealing time of PS. These results indicate that high molecular weight of PS with such circumstance suppresses the mobility of the polymer chain, enhancing the surface tension of the polymer. We demonstrate that these de-wetting induced patterns attributed to the change of the mobility and the surface tension of PS chains, creating a high density of patterns with high reproducibility.</P>

Genome Sequence of Pectin-Degrading Alishewanella agri, Isolated from Landfill Soil

Kim, Jisun,Jung, Jaejoon,Sung, Jung-Suk,Chun, Jongsik,Park, Woojun American Society for Microbiology 2012 Journal of Bacteriology Vol.194 No.18

<B>ABSTRACT</B><P>Alishewanella agriBL06<SUP>T</SUP>(= KCTC 22400<SUP>T</SUP>= JCM 15597<SUP>T</SUP>) was isolated from landfill soil in Pohang, South Korea.A. agrishowed the ability to degrade pectin, a structural heteropolysaccharide present in the cell wall of plants. Here we report the genome sequence ofAlishewanella agriBL06<SUP>T</SUP>, the second sequenced strain in the genusAlishewanella.</P>

자동차 영업사원의 적응적 판매행위가 영업성과에 미치는 영향에 관한 연구

정지선(Jisun Jung),전중옥(Jungok Jeon),이은미(Eunmi Lee),서정환(Jeonghoan Seo) 한국인터넷전자상거래학회 2011 인터넷전자상거래연구 Vol.11 No.2

This study helps to understand the performance of salesperson's adaptive selling in the automobile business. The major objective of this study is to examine the relationship of salesperson's adaptive selling and performance, and to find the moderation role of CRM practice. Data were collected from 151 salespersons who are related to automobile sales. The data via intercept survey were based on self administered questionaries. Frequency, Cronbach' α and path analysis were used as statistical test tool. Additionally, SPSS 12.0 were used for hierarchical regression analysis to find out the effect of the moderator. The results of the analysis largely supports the hypothesized framework and the major findings of this study are summarized as follows: First, H1 proposed that salesperson's adaptive selling would affect performance positively. The results found that salesperson's adaptive selling was directly related to performance, and thus, H1 was supported. Second, H2 proposed that CRM practice would moderate the relationship of salesperson's adaptive selling and performance. The results showed that when salesperson's adaptive selling affected performance positively, CRM practice was more effective. In conclusion, it can be posited that salesperson's adaptive selling and CRM practice are both important factors for performance in the increasingly competitive automobile business.

Alongshore Patterns of Sediment Transport in Kailua Beach, Hawaii

Lee Jung Lyul(이정렬),Jisun Jung(정지선),M. H. Teng(미쉘텡) 대한토목학회 2004 대한토목학회 학술대회 Vol.2004 No.10

의미 단서가 명칭실어증자의 명명하기에 미치는 영향

정지선 ( Jisun Jung ),강민구 ( Mingu Kang ) 사단법인 아시아문화학술원 2020 인문사회 21 Vol.11 No.6

본 연구는 명명하기과제 수행에서 단계별 의미단서가 명명하기능력에 미치는 영향을 알아보는데 그 목적이 있다. 이를 위해 실어증지수와 유형을 일치시킨 명칭실어증 환자 33명을 대상으로 분석하였다. 명명하기과제에서 기존의 K-BNT 의미단서와 단계별 의미단서를 제공하여 3단계로 구성된 의미단서 간의 정반응 점수에 차이가 있는지를 분석하였다. 그 결과 첫째, 명칭실어증자의 명명하기에서 단계별 의미단서가 K-BNT 의미단서에 비해 이름대기 수행력이 증가하였다. 둘째, 세 단계로 구성된 단계별 의미단서간의 정반응 점수를 분석한 결과, 단계별 의미단서에서 유의한 차이가 나타났다. 이러한 결과를 통해, 단계별 의미단서는 명명하기 수행력 향상에 효과적이라는 것을 의미한다. 향후 다양한 낱말들의 위계성이 반영된 단계별 의미체계가 구축된다면 실어증자의 명명하기 수행력 향상에 도움을 줄 수 있을 것으로 사료된다. The purpose of this study is to find out the effect of step by step semantic cues on naming ability in the naming task. The analysis was conducted on 33 patients with anomic aphasia matching the aphasia quotient and type. The naming task provided the existing K-BNT semantics and step by step semantics. The difference in the positive response scores between the semantic cues composed of three stages was analyzed. As a result, first, Naming task of anomic aphasia showed improved performance in the step by step semantic cues compared with the K-BNT semantic cues. Second, An analysis of the positive response scores between the three step semantic cues showed significant differences in step by step semantic cues. Through these results, Step by step semantics cue that effective in improving naming task performance. In the future, if a step by step semantic system hierarchies of various words is established, it is thought can help improve the naming task performance of aphasia.

Correlations between the Clinical and Ultrasonographic Parameters of Congenital Muscular Torticollis without a Sternocleidomastoid Mass

Hwang Jisun,Khil Eun Kyung,Jung Soo Jin,Choi Jung-Ah 대한영상의학회 2020 Korean Journal of Radiology Vol.21 No.12

Objective: To determine whether ultrasonography at initial presentation can help assess the clinical severity of congenital muscular torticollis (CMT) in infants without a sternocleidomastoid muscle (SCM) mass. Materials and Methods: This retrospective study included 71 infants aged less than 12 months (4.1 ± 2.3 months) with non-mass CMT. The clinical severity was divided into three grades (groups 1–3) based on the degree of lateral head bending or cervical rotation. The difference (SCM-D) and ratio (SCM-R) between the maximal thickness of the affected and non-affected SCMs were obtained using transverse and longitudinal ultrasonography. The sonographic echotexture and echogenicity of the involved SCM were reviewed. Results: A significant difference was observed in the SCM-D (0.42 ± 0.30 mm in group 1; 0.74 ± 0.50 mm in group 2; 1.14 ± 0.85 mm in group 3; p = 0.002) and SCM-R (1.069 ± 0.067 in group 1; 1.129 ± 0.087 in group 2; 1.204 ± 0.150 in group 3; p = 0.001) among the groups when measured along the longitudinal but not along the transverse ultrasonography plane. The areas under the curves of the SCM-R and SCM-D measured by longitudinal ultrasonography were 0.731 (p < 0.001) and 0.731 (p < 0.001) for group 1 versus groups 2–3. The proportions of heterogeneous echotexture or hyperechogenicity in the involved SCM did not differ significantly among the three clinical groups (all p > 0.05). Conclusion: Ultrasonography can aid in assessing the clinical severity of CMT in infants without an SCM mass at the time of initial diagnosis. The SCM-R and SCM-D helped grade the clinical severity when obtained by longitudinal scan.