P211 : Red blood cell distribution width is increased in patients with psoriasis vulgaris: a retrospective study on 261 patients

( Dae Suk Kim ),( Dongyun Shin ),( Minseok Lee ),( Hyunjoong Jee ),( Tae Gyun Kim ),( Sung Hee Kim ),( Do Young Kim ),( Soo Min Kim ),( Min Geol Lee1 ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2

Background: Circulating inflammatory cytokines and markers are increased in patients with psoriasis. Recent studies have shown that a higher red blood cell distribution width (RDW) is associated with disease activity in various disorders. Objectives: Our objective was to investigate whether RDW is increased in psoriasis patients, and to evaluate its association with disease severity. Methods: We conducted a retrospective study of psoriasis patients seen in single hospital in Korea. Demographic data, hematologic parameters and disease severity were collected. Results: A total of 261 psoriasis patients and 102 healthy controls were included in our study. The RDW value was significantly increased in psoriasis patients compared to healthy control (p=0.037). Compared to mild psoriasispatients (PASI<7), moderate to severe patients (PASI≥7) showed significantly higher RDW values (p=0.044). RDW did not show significant correlation with PASI (p=0.358). When patients were divided into two groups according to their RDW value (<14.6% and ≥14.6%), the mean value of PASI was not significantly different (p=0.219). Conclusion: Patients with psoriasis showed increased RDW values compared to healthy controls. It was also higher in moderate and severe disease group than mild group. RDW values were increased in psoriasis patients and it is possible that RDW value reflects the inflammatory status of psoriasis, but this needs to be evaluated in near future.

Association Between Suicide and Drinking Habits in Adolescents

Ji Won Lee,Bong-Jo Kim,Cheol-Soon Lee,Boseok Cha,So-Jin Lee,Dongyun Lee,Jiyeong Seo,Young-Ji Lee,Youn-Jung Lee,Eunji Lim,Jae-Won Choi 대한소아청소년정신의학회 2021 소아청소년정신의학 Vol.32 No.4

Objectives: Adolescent suicide is a serious social problem. Adolescent alcohol use is one of the most important risk factors for adolescent suicide. This study aimed to identify the relationship between drinking habits and suicide among Korean adolescents. Methods: Data from the 14th and 15th Korean Youth Risk Behavior Web-based Survey, conducted in 2018 and 2019, were used for analysis. Multiple logistic regression analysis was used to identify the relationship between drinking habits—including the age of drinking initiation, frequency of drinking, average drinking amount, frequency of drunkenness—and suicidal ideation, plans, and attempts. Results: Even after adjusting for age, sex, school grade, academic achievement, socioeconomic status, depression, stress, and drinking habits, the frequencies of drinking and drunkenness increased the risk of suicide attempts. Suicide attempts were associated with the frequency of drinking in girls and middle school students, and with the frequency of drunkenness in boys and high school students. Conclusion: This study identified associations between drinking habits (the age of drinking initiation, frequency of drinking, average amount of drinking, frequency of drunkenness) and suicidal behavior in adolescents. Our findings suggest that to prevent adolescent suicide, it might be necessary to investigate drinking habits, including the frequencies of drinking and drunkenness. Moreover, considering the differences in sex and school grade, it is important to include the individual group characteristics when evaluating drinking habits.

The Mediating Effect of Impulsivity on Resilience and Depressive Symptoms In Korean Conscripts

Dongyun Lee,So-Jin Lee,Chul-Soo Park,Bong-Jo Kim,Cheol-Soon Lee,Boseok Cha,Ji-Yeong Seo,Jae-Won Choi 대한신경정신의학회 2019 PSYCHIATRY INVESTIGATION Vol.16 No.10

Objective Resilience and impulsivity have opposite effects on depression in stressful situations. This study aimed to investigate the association among resilience, impulsivity, and depression in young males. Methods The participants consisted of 429 conscripts who underwent military training over 5 weeks. The surveys included the Connors- Davidson Resilience Scale-Korean version, the Barratt Impulsiveness Scale-11-Revised, and the Center for Epidemiological Studies- Depression Scale. The surveys were administered both before and after training. Results When simultaneously considering impulsivity and resilience, resilience was not associated with depression. Impulsivity had a complete negative mediating effect on resilience and depressive symptoms. Impulsivity is a significant negative mediating factor for the protective effect of resilience on depression. Conclusion This study recommends considering impulsivity when evaluating the protective role of resilience against depression.

Association between Early Spermarche and Suicide Attempts in Boys: the Korea Youth Risk Behavior Web-based Survey

Lee Young-Ji,Ahn In-Young,Kim Bong-Jo,Lee Cheol-Soon,Cha Boseok,Lee So-Jin,Seo Jiyeong,Choi Jae-Won,Lee Youn Jung,Lim Eunji,Lee Dongyun 대한의학회 2021 Journal of Korean medical science Vol.36 No.11

Background: Puberty is a biologically and psychologically unstable period, and pubertal changes differ by sex. However, most previous studies on pubertal timing and suicide have focused on girls. This study investigated the association between early spermarche and suicide attempts in boys. Methods: We analyzed a nationally representative sample of Korean adolescents (The Korea Youth Risk Behavior Web-Based Survey, KYRBS) that included approximately 35,000 boys annually from 2011 to 2015. Pubertal timing in boys was defined by spermarche. Complex sampling logistic regression analyses were performed to evaluate the odds ratios (ORs) for suicide attempts between the early and average spermarche groups. Results: The ORs for suicide attempts in boys with early spermarche were significantly higher than those in boys with average spermarche after adjustment for age, perceived stress, depressive symptoms, and suicidal ideation. The ORs from 2011 to 2015 were as follows: 1.782 (P < 0.001), 1.490 (P = 0.002), 1.693 (P < 0.001), 1.541 (P = 0.001), and 1.393 (1.024–1.895; P = 0.035), respectively. Conclusion: These findings suggest that early pubertal timing is a risk factor for suicide attempts in Korean boys after adjustment for depressive symptoms, perceived stress, and suicidal ideation, which have been previously reported as risk factors for suicide attempts. Therefore, careful attention should be paid to the prevention of suicide in boys who experience early spermarche in Korea.

초고층 건물의 시공단계 기밀성능 측정 및 개선효과 분석

이동윤(Dongyun Lee),이주호(Jooho Lee),김규동(Kyudong Kim),이준서(Junseo Lee),김영학(Younghak Kim) 대한설비공학회 2016 대한설비공학회 학술발표대회논문집 Vol.2016 No.11

BIM 기반의 준설매립전용 Library Browser 개발

이동윤(Dongyun Lee),이준호(Junho Lee),이상웅(Sangwoong Lee),최차석(Chaseok Choi),구본효(Bonhyo Gu) 한국지반환경공학회 2014 한국지반환경공학회논문집 Vol.15 No.3

본 연구에서는 준설매립분야의 설계자동화를 위하여 준설토 투기장 설계 시 고려되는 상부 및 하부 구조물을 대상으로 Library를 구축하고, 이를 통합?관리할 수 있는 브라우저를 개발하였다. 개발 Library는 주요 단면제원을 변수화하여 형상의 가변성확보가 가능한 파라메트릭 모델링 방법을 이용하여 작성하였으며, 작업환경에 맞게 표준횡단 및 패밀리 Library로 구분하여 작성하였다. 작성된 Library를 특성별로 구분하여 객체를 관리하고 BIM 기반 모델링 작업 시 객체의 적용이 간편하도록 C# 언어를 이용하여 브라우저를 개발하였다. 개발된 브라우저를 BIM 기반의 3차원 캐드 프로그램에 연동함으로써 간편하게 3차원 모델링, 도면작성 및 물량산출이 가능하고 신규 Library의 작성 및 관리 또한 가능하다. This study has been conducted to building a library intended for structures considered in the design of reclamation for design automation and developing browser for integrated management system. The library has been developed using a parametric modeling method capable of changing section shape, also classifying standard crossing and family library, has been developed according to the working environment. Classified library by the characteristics manages objects and working modeling on based BIM has been developed browser using the C# program for objects to use conveniently. By interworking between developed Browser and 3D Autocad based BIM, it is possible to use easily at design drafting, calculating quantities, developing a new library, and managing a library. The browser using effectively exclusive library to reclamation is developed in this study.

양극성 장애 입원 환자에서 비타민 D와 회복력

김창근(Chang-Geun Kim),김봉조(Bong-Jo Kim),이철순(Cheol-Soon Lee),이소진(So-Jin Lee),이동윤(Dongyun Lee),서지영(Ji-Yeong Seo),최재원(Jae-Won Choi),이영지(Young-Ji Lee),이윤정(Youn Jung Lee),임은지(Eunji Lim),차보석(Boseok Cha) 대한생물치료정신의학회 2021 생물치료정신의학 Vol.27 No.3

Objectives:The purpose of this study was to investigate the relationship between serum vitamin D concentration and resilience in patients hospitalized with bipolar disorder. Methods:Serum vitamin D levels were measured on day 1 of hospitalization in 64 patients with bipolar disorder, who were diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition. The Connor-Davidson Resilience Scale and the Korean version of the Inventory for Depressive Symptomatology (KIDS) were administered to these patients, and symptoms of mania were evaluated using the Young Mania Rating Scale (YMRS). Patients were then categorized into vitamin D sufficient and deficient groups based on a serum vitamin D cut-off of 20 ng/mL. Analysis of covariance (ANCOVA) was performed to compare the resilience between the two groups, and multiple linear regression was performed to determine the association between serum vitamin D levels and resilience. Results:The vitamin D deficiency group had more depressive episodes than the sufficient group (p<0.05). ANCOVA showed that the vitamin D deficient group had significantly lower resilience scores than the sufficient group (p= 0.034). Moreover, multiple regression analyses conducted by controlling age, sex, body mass index, season of blood sampling, KIDS scores, and YMRS scores, showed a significant association between serum vitamin D concentration and resilience in patients with bipolar disorder (p=0.001). Conclusions:This study suggested that vitamin D deficiency is associated with resilience as a protective factor against stress and trauma in patients with bipolar disorder. Further research is warranted to determine the causal relationship between vitamin D levels and resilience.

노인에서 COVID-19로 인한 불안감과 관련된 인식

임은지(Eunji Lim),김봉조(Bong-Jo Kim),이철순(Cheol-Soon Lee),차보석(Boseok Cha),이소진(So-Jin Lee),서지영(Jiyeong Seo),최재원(Jae-Won Choi),이영지(Young-Ji Lee),이윤정(Younjung Lee),이동윤(Dongyun Lee) 대한노인정신의학회 2021 노인정신의학 Vol.25 No.1

Objective: To investigate perceptions of coronavirus disease-19 (COVID-19) associated with anxiety caused by the COVID-19 epidemic in the elderly who are vulnerable to mental health problems. Methods: This study used data of a survey on perceptions of COVID-19 and changes in mental health of 1,000 out of residents in a province of Korea in April 2020. The survey included questions about psychological perceptions for COVID-19. Subjects were dived into two groups (<60 and ≥60). Binary logistic regression analyses were performed for evaluating the association between anxiety and perceptions about COVID-19 in each group. Results: Results of binary logistic regression analyses revealed that only ‘fear of getting infected myself’among perceptions for COVID-19 was associated with anxiety in the elderly aged more than 60 years. However, in adults aged less than 60 years, all perceptions for COVID-19 except impairment of performance were associated with such anxiety. Conclusion: We found that the anxiety for COVID-19 in elderly with age over 60 years was associated with ‘fear of getting infected myself’ rather than ‘fear of family or people around them’, unlike adults aged less than 60 years. These results can be applied in strategies for psychological quarantine against COVID-19 among the elderly.

A New Method to Quantify Contents of Stone Cell in Pear Flesh

Dongyun Lee,Daeil Kim,Sewon Oh,Jihyun Oh,Do-Yeon Cho,Keumsun Kim,Hae Won Jeong 한국원예학회 2020 한국원예학회 학술발표요지 Vol.2020 No.11

Large unstained cell values can be a valuable marker to aid in diagnosis of Sezary syndrome

( Dongyun Shin ),( Jimyung Seo ),( Minseok Lee ),( Hee Joo Kim ),( Min Geol Lee ),( Dae Suk Kim ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.2

Background: Erythroderma is caused by many factors. Although the majority of erythroderma are caused by benign diseases, it is very important to differentiate malignancy-related erythroderma, especially Sezary syndrome(SS). Therefore, it is important to find differentiating markers for SS among the patients with erythroderma. Objectives: We have evaluated the results of complete blood cell tests in patients with erythroderma to find whether it can be a useful marker for differentiating erythroderma patinets. Methods: We evaluated the number and the percentages of white blood cells, basophils, neutrophils and LUC of 63 erythroderma patients. Results: In multivariate binary logistic regression analysis, #LUC and %basophils showed significant association with the presence of SS. #LUC was the strongest predictor for the presence of SS in erythroderma patients(OR 1334.9, 95% CI 2.934-607446.629, P=0.021) and %basophils was also significant predictor(OR 7.951, 95% CI 1.036-61.014, P=0.046), too. ROC curve was created and the area under the curve(AUC) of #LUC was 97.76%(95% CI 94.24-101.3%, P=0.0004), and AUC of %basophils was 93.97%(95% CI 86.79-101.1%, P=0.0012). ROC curve analysis suggested that the optimal cut-off points for predicting SS were 0.33x103/レL for #LUC(100% sensitivity, 93.1% specificity) and 1.05% for %basophils(80% sensitivity, 94.83% specificity). Conclusion: We suggest that #LUC and %basophils can be a useful marker for differentiating SS from erythroderma.