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      • Laser-range-finder based Field Ridge Detecting for Transplanter

        ( Jiajun Zhu ),( Michihisa Iida ),( Hoang-son Le ),( Masahiko Suguri ),( Ryohei Masuda ),( Kouji Miyake ),( Satoru Konishi ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

        When a rice transplanter runs automatically in a rice paddy field, field ridge detection is an important part, it can provide the stop position for transplanter. In this paper, a method to detect the field ridge by a single Laser-Range-Finder equipped on the transplanter is presented. The base machine is an 8-row rice transplanter, this transplanter can be operated up to a maximum speed of 1.85 m/s. The LRF can determine the distance from transplanter to ridge in the real time, and depending on this distance, the transplanter decreases speed and stops automatically. The field test is conducted to evaluate the performance of the LRF based field ridge detection in the field. As the result, the detection accuracy is high enough for actual application.

      • KCI등재

        Experimental Investigation on Aerodynamic Interference of Vehicles on Single-Level Rail-Cum-Road Bridge under Crosswinds

        Jiajun He,Jin Zhu,Huoyue Xiang,Botao Zhang,Yongle Li,Bing Han 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.8

        Single-level rail-cum-road steel box girder is a relatively new form of bridge superstructure that accommodates railway and highway in the same level. The wind flow pattern over the bridge deck is quite complex and a new issue of aerodynamic interference between vehicles also rise up. This paper conducted an in-depth investigation on the aerodynamic characteristics of vehicles on a single-level rail-cum-road bridge as well as the aerodynamic interference among vehicles. The results reveal that the bridge deck makes the aerodynamic coefficients of vehicles on windward lanes vary a lot with respect to vehicle location and vehicle type, while it also well protects the train and leeward road vehicles from large wind load. Among all the vehicles, the van gets several of the largest aerodynamic coefficients and is considered as a critical vehicle. In terms of the vehicles’ interference, the upstream truck trailer brings significant aerodynamic variation for the overtaking vehicle, but its inadequate shelter effect yields fluctuation in the variation. An upstream truck trailer brings significant rise for the aerodynamic load of the train, larger distance between the train and the truck trailer will bring larger increase on the train’s aerodynamic load.

      • SCISCIESCOPUS

        Carbon-coated SnO<sub>2</sub>@C with hierarchically porous structures and graphite layers inside for a high-performance lithium-ion battery

        Li, Yao,Zhu, Shenmin,Liu, Qinglei,Gu, Jiajun,Guo, Zaiping,Chen, Zhixin,Feng, Chuanliang,Zhang, Di,Moon, Won-Jin The Royal Society of Chemistry 2012 Journal of materials chemistry Vol.22 No.6

        <P>A high-performance anode material was prepared from a hierarchically structured activated carbon which contains <I>in situ</I> graphene and nano-graphite. The activated carbon was immersed in a solution of SnCl<SUB>2</SUB>·2H<SUB>2</SUB>O and subjected to ultrasound. As a result, nanoparticles of SnO<SUB>2</SUB> were uniformly deposited on the surface of the activated carbon. The composite material was then coated with a thin layer of carbon by soaking it in a sucrose solution, followed by carbonization of the adsorbed sucrose at 500 °C. The resulting composite showed an outstanding high-rate cycling performance that can deliver an initial discharge capacity of 1417 mAh g<SUP>−1</SUP> and maintain a discharge capacity of more than 400 mAh g<SUP>−1</SUP> after 100 cycles at a high current density of 1000 mA g<SUP>−1</SUP>. This outstanding electrochemical performance is likely to be related to a unique combination of the excellent electrical conductivity of the activated carbon with graphite layers formed inside, its hierarchical pore structure which enhances lithium-ion transportation, and the carbon coating which alleviates the effects of volume changes, shortens the distance for Li<SUP>+</SUP> diffusion, facilitates the transmission of electrons, and keeps the structure stable.</P> <P>Graphic Abstract</P><P>Carbon-coated SnO<SUB>2</SUB>@C nanocomposite with hierarchically porous structures and graphite layers inside was prepared by ultrasound and hydrothermal treatment, which showed an outstanding high-rate cycling performance for lithium-ion battery. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c1jm14290a'> </P>

      • KCI등재

        Local Bond Stress-Slip Model of High-Strength Stainless Steel Wire Ropes in ECC

        Ke Li,Dapeng Zhao,Jiajun Fan,Juntao Zhu 대한토목학회 2022 KSCE Journal of Civil Engineering Vol.26 No.5

        Engineered cementitious composites (ECC) reinforced with high-strength stainless steel wire ropes (HSSSWR) is a new composite that has attracted much attention. Comprehensive understanding of the local bond stress-slip relationship of HSSSWR in ECC is a significant aspect to popularize the application of this new composite. In this research, the local bond stress-slip relationship between HSSSWR and ECC was investigated experimentally and theoretically, considering the influences of bond lengths, nominal diameters of HSSSWR and compressive strength of ECC. In order to accurately predict the bond stress and slip at different positions along the embedded length, a local bond stress-slip model was proposed for HSSSWR-ECC interface, and the model parameters were determined based on the pull-out test results and microsegment analysis of HSSSWR in ECC by using a nested iteration procedure. Furthermore, the three-dimension (3D) nonlinear finite element (FE) modeling method by using the proposed model was used to predict the bond-slip performance of HSSSWR in ECC. Finally, the global load-slip relationships calculated by using the iterative procedure and the 3D FE modeling method were compared with test results, which validated the acceptability of the developed local bond stress-slip model and the FE modeling method.

      • KCI등재

        One-Pot Electrodeposition of NiS Nanoparticles as an Efficient Electrode for Nonenzymatic H2O2 and Glucose Sensors

        Zhiheng Huang,Chunchuan Gu,Jiajun Wen,Langlang Zhu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.1

        In this paper, a new and one-pot electrodeposition method was expanded for the preparation of NiS nanoparticles-based electrochemical biosensor using metal-ion complexes as a precursor. Thioacetamide was used to control the production rate of NiS nanoparticles for the first time. The proposed electrochemical sensor was characterized by energy dispersive X-ray spectroscopy (EDX), field emission scanning electron microscope (FESEM), cyclic voltammograms (CV), and electrochemical impedance spectra (EIS). Experiment parameters were optimized. Under the optimized condition, the prepared NiS-based biosensor exhibited excellent electrocatalytic oxidation of H2O2 and glucose due to their small size. It provided fast and sensitive strategy for detecting H2O2 and glucose in the range of 1–5000 and 1–1000 μM. The detection limit of 0.257 and 0.3 μM was obtained for H2O2 and glucose. The mechanisms were also analyzed. The proposed biosensor exhibited excellent anti-interference and repeatability. Furthermore, it was applied in the actual sample analysis, such as human blood serum.

      • KCI등재

        Analytical and Experimental Studies on All-Steel Buckling Restrained Brace with Double Steel Tubes

        Jinhe Gao,Jiahuan Xi,Jiajun Ding,Yuwen Xu,Junwen Zhu,Yi Chang 한국강구조학회 2022 International Journal of Steel Structures Vol.22 No.1

        This study proposes a new type of all-steel buckling restrained brace with double steel tubes composed of an inner round steel tube and an outer square steel tube, the inner core adopting a cruciform section and an H-section. These two types of cross-sectional inner cores have larger cross-sectional stiff ness than round bars and better meet the requirement that inner core should be easy to yield but not easy to buckle. In this study, a theoretical design method for designing the proposed BRB in a simplifi ed and optimal way is presented. The assembly scheme, constraint system, and overall structure are defi ned. The quasi-static tests of two brace specimens under a cyclic load are carried out to verify the brace's mechanical performance, axial strain distribution, and energy dissipation capacity. These results show that, relying on these two types of cross-sections, the hysteresis curves of all-steel buckling restrained braces with double-steel tubes are overall in good shape and stable. In addition, its energy dissipation performance is stable without any widespread instability phenomena. Also, the inner core has a stable plastic deformation capacity even after yielding, based on the comparative analysis of axial strain response of each components. Both specimens can meet the requirements of seismic design.

      • Morphological effects on surface-enhanced Raman scattering from silver butterfly wing scales synthesized via photoreduction.

        Tan, Yongwen,Zang, Xining,Gu, Jiajun,Liu, Dingxin,Zhu, Shenmin,Su, Huilan,Feng, Chuanliang,Liu, Qinglei,Lau, Woon Ming,Moon, Won-Jin,Zhang, Di American Chemical Society 2011 Langmuir Vol.27 No.19

        <P>Through a simple room-temperature photoreduction process, this letter conformally replicates 3D submicrometer structures of wing scales from two butterfly species into Ag to generate practical surface-enhanced Raman scattering (SERS) substrates. The Ag replicas of butterfly scales with higher structural periodicity are able to detect rhodamine 6G at a low concentration down to 10(-9) M, which is three orders of magnitude lower than the detectable concentration limit of using quasi-periodic Ag butterfly structures. This result presents a way to select suitable scale morphologies from 174,500 species of Lepidopterans to replicate, as consumable SERS substrates with low cost and high reproducibility.</P>

      • KCI등재

        Favorable Immunotherapy Plus Tyrosine Kinase Inhibition Outcome of Renal Cell Carcinoma Patients with Low CDK5 Expression

        Xianglai Xu,Ying Wang,Zhaoyi Chen,Yanjun Zhu,Jiajun Wang,Jianming Guo 대한암학회 2023 Cancer Research and Treatment Vol.55 No.4

        Purpose Immunotherapy (IO) plus tyrosine kinase inhibitor (TKI) has become the first-line treatment for advanced renal cell carcinoma, despite the lack of prognostic biomarkers. Cyclin-dependent kinase 5 (CDK5) affects the tumor microenvironment, which may influence the efficacy of TKI+IO. Materials and Methods Two cohorts from our center (Zhongshan Metastatic Renal Cell Carcinoma [ZS-MRCC] cohort, Zhongshan High-risk Localized Renal Cell Carcinoma [ZS-HRRCC] cohort) and one cohort from a clinical trial (JAVELIN-101) were enrolled. The expression of CDK5 of each sample was determined by RNA sequencing. Immune infiltration and T cell function were evaluated by flow cytometry and immunohistochemistry. Response and progression-free survival (PFS) were set as primary endpoints. Results Patients of low CDK5 expression showed higher objective response rate (60.0% vs. 23.3%) and longer PFS in both cohorts (ZS-MRCC cohort, p=0.014; JAVELIN-101 cohort, p=0.040). CDK5 expression was enhanced in non-responders (p < 0.05). In the ZS-HRRCC cohort, CDK5 was associated with decreased tumor-infiltrating CD8+ T cells, which was proved by immunohistochemistry (p < 0.05) and flow cytometry (Spearman’s ρ=–0.49, p < 0.001). In the high CDK5 subgroup, CD8+ T cells revealed a dysfunction phenotype with decreased granzyme B, and more regulatory T cells were identified. A predictive score was further constructed by random forest, involving CDK5 and T cell exhaustion features. The RFscore was also validated in both cohorts. By utilizing the model, more patients might be distinguished from the overall cohort. Additionally, only in the low RFscore did TKI+IO outperform TKI monotherapy. Conclusion High-CDK5 expression was associated with immunosuppression and TKI+IO resistance. RFscore based on CDK5 may be utilized as a biomarker to determine the optimal treatment strategy.

      • KCI등재

        Rhaponticin suppresses the hypoxia-induced factor-1 alpha-mediated aggressive phenotype of tongue squamous cell carcinoma

        Wu Yuan,Wan Xiaowen,Shao Yisen,Wang Wei,Huang Wenquan,Zhu Jiajun,Jiang Lin 대한독성 유전단백체 학회 2024 Molecular & cellular toxicology Vol.20 No.2

        Emerging evidence suggests that rhaponticin, a stilbene monomeric compound isolated from North China rhubarb, has been shown to exhibit significant biological activity against tumors. However, the anticancer effects and mechanisms of rhaponticin in tongue squamous cell carcinoma (TSCC) remain elusive.We investigated the changes of migration and invasion abilities and EMT progression of TSCC cells treated with different concentrations of rhaponticin under hypoxia, as well as the possible mechanisms, in order to initially explore the effects of rhaponticin on the biological characteristics of TSCC cells under hypoxia.The number of cell migration and invasion was prominently increased, E-cadherin protein was down-regulated, and N-cadherin and HIF-1α protein expression was elevated under hypoxia. Rhaponticin intervention strikingly prevented the increased abilities of migration and invasion and EMT of TSCC cells under hypoxia. This was followed by further validation finding that rhaponticin indeed leads to reduced HIF-1α post-transcriptional activity. Mechanistically, rhaponticin may bind to aryl-hydrocarbon nuclear translocator (ARNT) domain of HIF-1α.Rhaponticin repressed the invasion and migration abilities and EMT process of TSCC cells under a hypoxic environment in vitro by targeted suppression of HIF-1α. Background Emerging evidence suggests that rhaponticin, a stilbene monomeric compound isolated from North China rhubarb, has been shown to exhibit significant biological activity against tumors. However, the anticancer effects and mechanisms of rhaponticin in tongue squamous cell carcinoma (TSCC) remain elusive. Objective We investigated the changes of migration and invasion abilities and EMT progression of TSCC cells treated with different concentrations of rhaponticin under hypoxia, as well as the possible mechanisms, in order to initially explore the effects of rhaponticin on the biological characteristics of TSCC cells under hypoxia. Results The number of cell migration and invasion was prominently increased, E-cadherin protein was down-regulated, and N-cadherin and HIF-1α protein expression was elevated under hypoxia. Rhaponticin intervention strikingly prevented the increased abilities of migration and invasion and EMT of TSCC cells under hypoxia. This was followed by further validation finding that rhaponticin indeed leads to reduced HIF-1α post-transcriptional activity. Mechanistically, rhaponticin may bind to aryl-hydrocarbon nuclear translocator (ARNT) domain of HIF-1α. Conclusions Rhaponticin repressed the invasion and migration abilities and EMT process of TSCC cells under a hypoxic environment in vitro by targeted suppression of HIF-1α.

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