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      • SCOPUSKCI등재

        The Relation Among Canadian, Mexican, and United States Short-Term Money Markets : A Pre-NAFTA Analysis

        Zhou, Su,Truett, Lila,Truett, Dale 세종대학교 국제경제연구소 1996 Journal of Economic Integration Vol.11 No.3

        This study uses cointegration analysis to examine linkages among the financial markets of Canada, Mexico, and the United States. The results are consistent with the hypotheses that long-run equilibrium relationships exist between Canadian and U.S. short-term interest rates and between Canadian and U.S. money supplies, respectively. The U.S. variables are found to have been a dominant force in the respective relationships with the Canadian variables. However, out findings do not lend support to the hypotheses of a cointegrating relationship between the short-term interest rate or the monetary base of Mexico and those of the United States of Canada. Nevertheless, we anticipate that the financial markets of Mexico will become more closely connected with those of the other two NAFTA countries in the future as NAFTA is implemented. (JEL Classification: F36)

      • Anti-tumor Efficacy of a Hepatocellular Carcinoma Vaccine Based on Dendritic Cells Combined with Tumor-derived Autophagosomes in Murine Models

        Su, Shu,Zhou, Hao,Xue, Meng,Liu, Jing-Yu,Ding, Lei,Cao, Meng,Zhou, Zhen-Xian,Hu, Hong-Min,Wang, Li-Xin Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

        The majority of hepatocellular carcinoma (HCC) patients have a poor prognosis with current therapies, and new approaches are urgently needed. We have developed a novel therapeutic cancer vaccine platform based on tumor cell derived autophagosomes (DRibbles) for cancer immunotherapy. We here evaluated the effectiveness of DRibbles-pulsed dendritic cell (DC) immunization to induce anti-tumor immunity in BALB/c mouse HCC and humanized HCC mouse models generated by transplantation of human HCC cells (HepG2) into BALB/c-nu mice. DRibbles were enriched from H22 or BNL cells, BALB/c-derived HCC cell lines, by inducing autophagy and blocking protein degradation. DRibbles-pulsed DC immunization induced a specific T cell response against HCC and resulted in significant inhibition of tumor growth compared to mice treated with DCs alone. Antitumor efficacy of the DCs-DRibbles vaccine was also demonstrated in a humanized HCC mouse model. The results indicated that HCC/DRibbles-pulsed DCs immunotherapy might be useful for suppressing the growth of residual tumors after primary therapy of human HCC.

      • Polymorphisms of TERT and CLPTM1L and the Risk of Hepatocellular Carcinoma in Chinese Males

        Su, Ling-Yan,Li, Xue-Lian,Shen, Li,Zhang, Yue,Zhao, Meng-Meng,Yin, Zhi-Hua,Su, Hong-Ying,Zhou, Bao-Sen Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.19

        Background: Telomerase reverse transcriptase (TERT) and cleft lip and palate trans-membrane 1 like (CLPTM1L) genes located on chromosome 5p15.33 are known to influence the susceptibility to various cancers. Here, we examined the association of TERT and CLPTM1L single nucleotide polymorphisms (SNPs) with hepatocellular carcinoma (HCC). Materials and Methods: Genotyping of TERT SNP rs2736098 and CLPTM1L SNP rs401681 was performed using TaqMan allelic discrimination assays in a case-control study of 201 HCC cases and 210 controls in a Chinese male population. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using logistic regression analyses. Results: Both the rs2736098 T allele of TERT and the rs401681 T allele of CLPTM1L were associated with a significantly increased risk of HCC (adjusted odds ratio [OR]=1.605, 95% confidence interval [CI]=1.164-2.213; adjusted OR=1.399, 95%CI=1.002-1.955, respectively). Individuals carrying both TERT and CLPTM1L risk genotypes had an even higher risk of HCC (adjusted OR=4.420, 95%CI= 2.319-8.425). The TERT rs2736098 T allele was also significantly associated with the level of the HCC clinical indicator alpha-fetoprotein (P=0.026). Conclusions: Our results show that genetic variants of TERT and CLPTM1L may contribute to HCC susceptibility in Chinese males.

      • SCOPUSKCI등재

        The Relations Among Canadian, Mexican, and United States Short-Term Money Markets: A Pre-NAFTA Analysis

        ( Su Zhou ),( Dale Truett ),( Lila Truett ) 세종대학교 경제통합연구소 1996 Journal of Economic Integration Vol.11 No.3

        This study uses cointegration analysis to examine linkages among the financial markets of Canada, Mexico, and the United States. The results are consistent with the hypotheses that long-run equilibrium relationships exist between Canadian and US. short-term interest rates and between Canadian and US. money supplies, respectively. The U.S. variables are found to have been a dominant force in the respective relationships with the Canadian variables. However, our findings do not lend support to the hypotheses of a cointegrating relationship between the short-term interest rate or the monetary base of Mexico and those of the United States or Canada. Nevertheless, we anticipate that the financial markets of Mexico will become more closely connected with those of the other two NAFTA countries in the future as NAFTA is implemented. (JEL Classification: F36)

      • KCI등재

        A positive feedback loop of heparanase/ syndecan1/nerve growth factor regulates cancer pain progression

        Xiaohu Su,Bingwu Wang,Zhaoyun Zhou,Zixian Li,Song Tong,Simin Chen,Nan Zhang,Su Liu,Maoyin Zhang 대한통증학회 2023 The Korean Journal of Pain Vol.36 No.1

        Background: The purpose of this research was to assess the role of heparanase (HPSE)/syndecan1 (SDC1)/nerve growth factor (NGF) on cancer pain from melanoma. Methods: The influence of HPSE on the biological function of melanoma cells and cancer pain in a mouse model was evaluated. Immunohistochemical staining was used to analyze HPSE and SDC1. HPSE, NGF, and SDC1 were detected using western blot. Inflammatory factors were detected using ELISA assay. Results: HPSE promoted melanoma cell viability, proliferation, migration, invasion, and tumor growth, as well as cancer pain, while SST0001 treatment reversed the promoting effect of HPSE. HPSE up-regulated NGF, and NGF feedback promoted HPSE. High expression of NGF reversed the inhibitory effect of HPSE down-regulation on melanoma cell phenotype deterioration, including cell viability, proliferation, migration, and invasion. SST0001 down-regulated SDC1 expression. SDC1 reversed the inhibitory effect of SST0001 on cancer pain. Conclusions: The results showed that HPSE promoted melanoma development and cancer pain by interacting with NGF/SDC1. It provides new insights to better understand the role of HPSE in melanoma and also provides a new direction for cancer pain treatment.

      • SCIESCOPUSKCI등재
      • KCI등재

        High-efficiency degradation of quinclorac via peroxymonosulfate activated by N-doped CoFe2O4/Fe0@CEDTA hybrid catalyst

        Lezhu Su,Lizhou Ou,Yujiao Wen,Yifan Wang,Weilin Zhao,Zhi Zhou,Mei-e Zhong,YONGFA ZHU,Nan Zhou 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.102 No.-

        Exploring catalyst materials which are advancing, recyclable and with high catalytic performances toremove persistent organic pollutants such as Quinclorac (QNC) is important. In this work, a novel Ndopedcarbon support CoFe2O4/Fe0 hybrid catalyst (CFO/Fe@C) was in situ formed by a simple coprecipitationand calcination process. Fine intergrowth crystal CoFe2O4 and Fe0 were uniformly dispersedon the N-doped porous carbon that derived from the raw material Ethylene Diamine Tetraacetic Acid(EDTA), which also provided chelating effect to prevent the agglomeration of the metals. Interestingly,the Fe0 could only be formed with the presence of cobalt, possibly due to the increased reduction propertyresulted from the particle refinement. The as-formed Fe0 could not only activate the peroxymonosulfate(PMS) but also reduce the Co3+, resulting in a synergistic impact to remarkably enhance thedegradation performance. Besides, the N-doped porous carbon can also benefit the degradation of pollutantby strengthening the electron transfer. A good degradation efficiency of QNC was obtained in CFO/Fe@C-PMS system and most of the QNC had been degraded to carbon dioxide, water and other smallmolecular organisms. The removal rate remained over 70% after four reuses and the material could beeasily recovered from the solution due to the good magnetic properties. Therefore, the as-preparedCFO/Fe@C catalyst should be an ideal catalyst for the removal of organic pollutants.

      • KCI등재

        印尼华侨企业 Lippo Group的发展与竞争力研究

        周素洁 ( Su-jie Zhou ),陈邦博 ( Bang-bo Chen ),김한얼 ( Hann-earl Kim ),邱爱林 ( Ail-in Qiu ),崔明哲 ( Myeong-cheol Choi ) 한중사회과학학회 2024 한중사회과학연구 Vol.22 No.1

        印度尼西亚是东南亚最大的经济体之一, 其经济近年来发展迅速。在印尼的经济发展中, 其经济快速增长的核心在于海外华人企业。作为印尼最大的华人企业家之一, 力宝集团在印尼的经济发展中发挥着重要作用。在房地产领域, 力宝集团是印尼最大的房地产开发商之一, 在东南亚拥有广泛的业务网络。它在金融领域也有强大的实力, 拥有银行、证券公司、保险公司和其他金融机构。此外, 该集团还在医疗、教育、零售等领域拥有业务。力宝集团通过在印尼的投资和扩张, 为当地经济带来了就业机会和增长动力。力宝集团不仅是印尼经济的重要支柱, 还致力于社会责任和可持续发展, 为印尼社会做出了积极贡献。它积极参加社会公益事业, 包括教育、医疗、救灾等。 力宝集团在印尼经济发展中扮演重要角色,但韩中两国对其研究较少。因此, 本研究对企业的发展历史和企业的相关业务领域进行了调查, 并采用SWOT分析法和五力模型对力宝集团的企业竞争力进行了分析。本研究的目的在于通过对印尼最大华人企业集团力宝集团的研究, 分析其发展历程、业务领域和竞争力等方面的特点, 为印尼和韩国的海外华人企业研究做出学术贡献, 并为韩国企业进入印尼提供启示。 Indonesia is one of the largest economies in Southeast Asia, and its economy has developed rapidly in recent years. In Indonesia’s economic development, the core of its rapid economic growth lies in overseas Chinese enterprises. As one of the largest Chinese entrepreneurs in Indonesia, Lippo Group plays an important role in Indonesia’s economic development. In the field of real estate, Lippo Karawaci is one of the largest real estate developers in Indonesia, which has an extensive business network in Southeast Asia. It also has strong strength in the financial field, and owns banks, securities companies, insurance companies and other financial institutions. In addition, the group also has businesses in healthcare, education, retail and more. Lippo Group has brought employment opportunities and growth momentum to the local economy through its investment and expansion in Indonesia. Lippo Group is not only an important pillar of the Indonesian economy, but also committed to social responsibility and sustainable development, making positive contributions to Indonesian society. It actively participates in social public welfare undertakings, including education, medical care, disaster relief and so on. The Lippo Group plays an important role in Indonesia’s economic development, but it has been less studied in Korea and China. Therefore, this research investigates the history of the enterprise development and the relevant business fields of the enterprise. and analyzes the corporate competitiveness of Lippo Group using SWOT analysis and five forces model. The purpose of this study is to contribute academically to the study of overseas Chinese enterprises in Indonesia and Korea and to provide insights for Korean enterprises to enter Indonesia by studying Lippo Group, the largest Chinese enterprise group in Indonesia, and analyzing its characteristics in terms of its development history, business fields, and competitiveness.

      • KCI등재

        Estrogen promotes the onset and development of idiopathic scoliosis via disproportionate endochondral ossification of the anterior and posterior column in a bipedal rat model

        Shuhui Zheng,Hang Zhou,Bo Gao,Yongyong Li,Zhiheng Liao,Taifeng Zhou,Chengjie Lian,Zizhao Wu,Deying Su,Tingting Wang,Peiqiang Su,Caixia Xu 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-

        This study aimed to verify the effects of estrogen on the onset and development of adolescent idiopathic scoliosis and the mechanisms associated with these effects by constructing a pubescent bipedal rat model. Experiments were conducted to investigate whether scoliosis progression was prevented by a Triptorelin treatment. One hundred twenty bipedal rats were divided into female, OVX (ovariectomy), OVX + E2, Triptorelin, sham, and male groups. According to a spinal radiographic analysis, the scoliosis rates and curve severity of the female and OVX + E2 groups were higher than those in the OVX, Triptorelin, and male groups. The measurements obtained from the sagittal plane of thoracic vertebrae CT confirmed a relatively slower growth of the anterior elements and a faster growth of the posterior elements between T11 and T13 in the female and OVX + E2 groups than in the OVX and Triptorelin groups. Histomorphometry and immunohistochemistry revealed a significantly longer hypertrophic zone of the vertebral cartilage growth plates that expressed more type X collagen and less type II collagen in the OVX and Triptorelin groups than in the female and OVX + E2 groups. Ki67 immunostaining confirmed an increase in the proliferation of vertebral growth plate chondrocytes in the OVX group compared with the female and OVX + E2 groups. In conclusion, estrogen obviously increased the incidence of scoliosis and curve severity in pubescent bipedal rats. The underlying mechanism may be a loss of coupling of the endochondral ossification between the anterior and posterior columns. Triptorelin decreased the incidence of scoliosis and curve magnitudes in bipedal female rats. Introduction Adolescent

      • Research Progress on the Livin Gene and Osteosarcomas

        Li, Cheng-Jun,Cong, Yu,Liu, Xiao-Zhou,Zhou, Xing,Shi, Xin,Wu, Su-Jia,Zhou, Guang-Xin,Lu, Meng Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

        Osteosarcoma is a common malignant tumor of bone, but mechanisms underlying its development are still unclear. At present, it is believed that the inhibition of normal apoptotic mechanisms is one of the reasons for the development of tumors, so specific stimulation of tumor cell apoptosis can be considered as an important therapeutic method. Livin, as a member of the newly discovered inhibitor of apoptosis proteins (IAPs) family, has specifically high expression in tumor tissues and can inhibit tumor cell apoptosis through multiple ways, which can become a new target for malignant tumor treatment (including osteosarcoma) and might of great significance in the clinical diagnosis of tumors and the screening of anti-tumor agents and carcinoma treatment.

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