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Zhang Xueluo,Chen Yanhua,Wang Xianping,Zhang Zhiping,Wang Jun,Shen Yan,Hu Yuanjing,Wu Xueqing 한국유전학회 2022 Genes & Genomics Vol.44 No.11
Background: Trophoblasts are the most important parts of the placenta in early pregnancy. Trophoblast cell dysfunction can induce embryo implantation insufficiency, thereby resulting in multiple diseases, including recurrent spontaneous abortion (RSA). A previous study indicates higher nerve injury-induced protein 1 (NINJ1) RNA levels in the villi tissues of RSA patients. Objective: This study aimed to investigate the effect of NINJ1 on trophoblast behaviors and pregnancy loss. Methods: Fresh villi tissues were obtained from with RSA patients and patients with artificial selective abortion for personal reasons, and NINJ1 expression in these tissues was detected. Extravillous trophoblast cell line HTR-8/SVneo was transfected with small-interfering RNA targeting NINJ1 or NINJ1 overexpression vector to perform loss-/gain-of-function experiments. Spontaneous abortion (SA) was induced by mating CBA/J females with DBA/2 males and the pregnant females were intraperitoneally injected with adenovirus vector carrying NINJ1 short hairpin RNA. Results: NINJ1 mRNA and protein levels were higher in the villi tissues of RSA patients than those of artificial selective abortion patients. NINJ1 knockdown promoted trophoblast cell proliferation, migration and invasion but inhibited cell apoptosis. Moreover, conditioned medium from NINJ1-depleted trophoblasts promoted the angiogenesis of human umbilical vein endothelial cells. NINJ1 knockdown also promoted activation of the signal transducer and activator of transcription 3 (STAT3) signaling pathway in trophoblasts, and STAT3 inhibitor reversed NINJ1 knockdown-induced effects on trophoblast behaviors. Furthermore, pregnancy loss was attenuated by NINJ1 inhibition. Conclusion: NINJ1 contributes to the development of SA and triggers trophoblast cell dysfunction through inhibiting the STAT3 pathway.
Xuan Zhang,ZhiPing Mao,Qian Wu,LinPing Zhang 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.3
In this report, hexakis (4-nitrophenoxy) cyclotriphosphazene (HNCP) and ethylene–octene copolymer grafted-maleic anhydride (POE-g-MA) were blended with pure PET together. The fire retardant ability and thermal stability of PET/HNCP/POE-g-MA were investigated respectively. The results indicated that HNCP and POE-g-MA had a synergic effect on the dripping resistance of PET besides the enhancement in flame retardancy to a certain degree. LOI values of the polymers with both POE-g-MA and 10 wt%HNCP were higher than that of pure PET and no drips just containing 1 wt%POE-g-MA. The reason was that HNCP could be well dispersed in PET when POE-g-MA was added, forming a more effective char layer and preventing dripping of polymers. Indeed, the morphology of charred residue of PET/HNCP/POE-g-MA showed that a porous protective layer with a dense surface was formed. The thermogravimetric analysis revealed that addition of HNCP improved the thermal stability and the yield of char residue of the PET/POE-g-MA systems. Based on a series of experiment results, the synergistic effect of HNCP and POE-g-MA on the anti-dripping of PET was also discussed. In the PET/HNCP/POE-g-MA system, POE-g-MA played a role of compatibilizer. The improved compatibility and dispersion provided the composite with the ideal flame retardancy, thermal stability and anti-dripping property.
Meng Zhang,Lili Liu,Jianan Li,Rui Zhan,Zhiping Wang,Haosheng Mi,Yunxiao Zhang 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.127 No.-
The catalytic mechanism of CoFe2O4 nanoparticles (NPs) was investigated in the system of electrochemicalenhanced heterogeneous activation of peroxymonosulfate (EC/CoFe2O4/PMS) with moxifloxacin(MOX) as target contaminant. The removal efficiencies of MOX in PMS, CoFe2O4, EC, CoFe2O4/PMS, andEC/CoFe2O4/PMS system were 18.3%, 36.1%, 43.7%, 96.9%, and 98.3%, respectively. Although there wasno synergy effect between EC and heterogeneous catalytic oxidation reaction (HCOR) on MOX removal,the value of apparent rate constant (karc) was much higher in EC/CoFe2O4/PMS system (0.24 min1) comparedwith CoFe2O4/PMS system (0.13 min1). Therefore, EC not only kept the structure of CoFe2O4 NPsstable, but also significantly accelerated the reaction rate of HCOR. Meanwhile, according to electrochemicalimpedance spectra of catalysts synthesized based on ion-substitution strategy and the EC-HCORexperimental results, the decisive role of „Co in PMS activation and the electron transfer between„Co and „Fe were confirmed. The TOC removal efficiency was reached 74.4% as the ratio of PMS toCoFe2O4 NPs being 0.8 mM to 50 mg/L (30 min), and further improved to 87.6% with batch addition(0.25 mM per 30 min) of PMS (120 min, CoFe2O4 = 100 mg/L). The research results could improve theunderstanding of catalytic mechanism of spinel oxide in electrochemical system.
Wenna Ge,Zhiping Zhou,Peng Zhang,Qingfang Zhang,Zhen Cao,Ruilong Zhang,Yongsheng Yan,Jiangdong Dai 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.66 No.-
Here, a new hierarchical porous carbon was first prepared from sodium lignosulphonate (SLS), an industrial by-product, via a confined carbonization and alkali activation methods using graphene oxide (GO) as template, and was used for ciprofloxacin (CIP) removal. The addition of GO nanosheets remarkably affected the morphology and pore structure. GLHPC-1, obtained at GO/SLS weight ratio of 1:100, possess a largest specific surface area of 3223 m2 g−1 and pore volume of 2.275 cm3 g−1, and thus exhibited an ultrahigh adsorption of 980.4 mg g−1 at 318 K and fast adsorption rate, as well as a good recycle ability in practice.
A Novel Spectral Clustering Based on Nonlinear Low Dimensional Embedding Feature Selection
Daowen Zhang,Zhiping Zhou 보안공학연구지원센터 2016 International Journal of Grid and Distributed Comp Vol.9 No.8
Spectral clustering is a clustering method based on algebraic graph theory. It has solid theoretical foundation and good performance of clustering. However, during the process of nonlinear low rank approximation, the traditional spectral clustering algorithm can’t effectively remove redundant features leading to the phenomenon that the local area can not distinguish. It also suffers from the high computational complexity of eigen-decomposition when dealing with the high dimensional data. In order to resolve the aforementioned problems, in this paper a novel Spectral clustering algorithm called LF-SC is proposed. Firstly, based on the nonlinear low dimensional embedding feature selection, we realize dimension reduction. The multi clustering structure of the data is captured, the potential manifold structure is fully discovered, and the geometry structure of the low dimensional manifold clustering is well maintained. Secondly, utilizing the SVD instead of EVD to obtain the eigenvectors reduces the computational complexity and maintain the local structure of the data as well as low dimensional manifold. Extensive experiments show the effectiveness and efficiency of our approach.
Steel scale-CaO composite catalyst for coke combustion and in-situ NO and SO2 removal
Li Zhang,Jingchong Yan,Zhiping Lei,Xianzhong Cao,Tiejun Chun,Zhanku Li,Hengfu Shui,Shibiao Ren,Zhicai Wang,Ying Kong 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.110 No.-
The performance of the steel scale (SS)-CaO composite on the combustion of coke nuts and in-situ reductionof SO2 and NO emission was investigated. Combustion experiments show that SS-CaO compositeaccelerates coke combustion and reduces SO2 and NO emissions concurrently. X-ray diffraction (XRD),scanning electron microscopy (SEM), and electron spin resonance (ESR) were used to investigate thecatalysis mechanism. Results show that SS and CaO have synergistic effect in in-situ denitration. Theincrease of SS and CaO fraction in the composites improve the denitration and sulfur fixation performance,respectively. The denitration activity is mainly attributed to the Fe2O3 in SS and Ca2Fe2O5 formedduring combustion. The desulfurization is due to the sulfur fixation with CaO. The increasing fraction ofCaO in the composites leads to the agglomeration of ash particles. 2%CaO is confirmed as the optimumaddition for catalytic combustion and emission reduction. This work sheds light on the cheap and effectivecatalysts that are potentially useful for iron ore sintering.
Cheng Zhiping,Wang Kaifang,Li Zhongwen,Wu Haotian,Zhi Changyi,Zhang Jinbin 대한전기학회 2024 Journal of Electrical Engineering & Technology Vol.19 No.1
In this paper, distributed secondary control of AC microgrid (MG) is studied and the infuence of communication delay on its control performance is analyzed and verifed. Firstly, a secondary control strategy for the MG is designed to achieve frequency recovery and proportional active power dispatch. Secondly, the stability of the MG system is analyzed in the frequency domain and a rigorous formula is derived to calculate the delay margin for the stability of the distributed secondary control with communication delays. The theoretical calculation results of the stability margin are approximately consistent with the simulation results, with an error of only 1.27%. The efects of the algorithm gains, communication topology, and connection weights on the delay margin are discussed based on the derived formula. The results demonstrate that the algorithm gain is inversely proportional to the delay margin. Changes in the communication topology and connection weights lead to changes in the maximum eigenvalue of the adjacency matrix L, which in turn afects the delay margin. Moreover, the infuence of time-varying delays is considered. The system can tolerate greater time-varying delays than fxed delays. Simulation and experimental results validate the efectiveness and feasibility of the proposed method.
A Large Gain Varialble range, Wide bandwidth Analog AGC Circuitry for a CMOS GPS Receiver
Dianwei Zhang,WeiMin Li,Zhiping Wen,Quan Pan 제어로봇시스템학회 2008 제어로봇시스템학회 국제학술대회 논문집 Vol.2008 No.10
In this paper, a large gain variable range, wide-band automatic gain circuitry (AGC) is introduced. Because we employed a simple mean detection technique, the AGC loop dissipates less than 1mA current under 3.3V supply voltage, and acts as a bandpass filter due to a DC offset cancellation scheme. The whole circuitry is designed in 0.35um JAZZ CMOS process, including variable gain amplifiers(VGAs)、fixed gain amplifiers 、gain control and DC offset cancellation part. The AGC provides a process independent gain variable range of 56dB, with a 70us loop lock time.