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- 저자 : Zhili Dong (검색결과 5 건)
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Association of Apolipoprotein E Polymorphisms with White Matter Lesions and Brain Atrophy
ZhiLi Niu,PingAn Zhang,Dong Li,ChengLiang Zhu,LiNa Feng,Ge Xiong,NaNa Song,Pei Tang,Feng Liu 대한신경정신의학회 2020 PSYCHIATRY INVESTIGATION Vol.17 No.2
Objective Apolipoprotein E (ApoE) is mainly synthesized in the liver. So far, it is unknown the relationship among APOE gene polymorphisms and WML, brain atrophy. Therefore, the aim of the study was to assess the associations of APOE gene polymorphisms in patients with WML and brain atrophy. Methods A total of 58 patients with WML, 128 patients with brain atrophy, 112 patients with co-occurrence of WML and brain atrophy and 95 healthy elderly volunteers were recruited from Renmin Hospital of WuHan University. Results Allele E3 was the most common allele. The alleles E2 had significantly higher levels of ApoB and lower age in WML group. The alleles E2 was associated with the lower level of ApoB, LDL-Ch, TCh, and sdLDL in co-occurrence group. The E3/E3 genotype has higher level of sdLDL, but lower age and female frequency in WML. The E3/E4 genotype had higher level of TG, but lower age in WML. Gender, Age, E2, Hyperhomocysteinemia and UA were also significantly associated with disease progression. Conclusion This study found that clinical data, lipids and metabolic complications were closely related to ApoE genotypes and alleles, and also disease progression and type.
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A general active-learning method for surrogate-based structural reliability analysis
Congyi Zha,Zhili Sun,Jian Wang,Chenrong Pan,Zhendong Liu,Pengfei Dong 국제구조공학회 2022 Structural Engineering and Mechanics, An Int'l Jou Vol.83 No.2
Surrogate models aim to approximate the performance function with an active-learning design of experiments (DoE) to obtain a sufficiently accurate prediction of the performance function’s sign for an inexpensive computational demand in reliability analysis. Nevertheless, many existing active-learning methods are limited to the Kriging model, while the uncertainties of the Kriging itself affect the reliability analysis results. Moreover, the existing general active-learning methods may not achieve a fully satisfactory balance between accuracy and efficiency. Therefore, a novel active-learning method GLM- CM is constructed to yield the issues, which conciliates several merits of existing methods. To demonstrate the performance of the proposed method, four examples, concerning both mathematical and engineering problems, were selected. By benchmarking obtained results with literature findings, various surrogate models combined with the proposed method not only provide an accurate reliability evaluation while highly alleviating the computational burden, but also provides a satisfactory balance between accuracy and efficiency compared to the other reliability methods.
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Renjie Ji,Yonghong Liu,Yanzhen Zhang,Xin Dong,Zhili Chen,Baoping Cai 대한기계학회 2011 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.25 No.6
Silicon carbide (SiC) ceramic has been widely used in modern industry. However, the beneficial properties of SiC ceramic make machining difficult and costly by conventional machining methods. This paper proposes a new process of machining SiC ceramic using end electric discharge (ED) milling. The process is able to effectively machine a large surface area on SiC ceramic at low cost and no environmental pollution. The effects of emulsion concentration, emulsion flux, milling depth, copper electrode number, and copper electrode diameter on the process performance such as the material removal rate, electrode wear ratio, and surface roughness have been investigated. In addition, the microstructure of the machined surface is examined with a scanning electron microscope, and the material removal mechanism of SiC ceramic during end ED milling is obtained.
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Magnetic Anisotropies in Cobalt-Nickel Ferrites (NixCo1-xFe2O4)
Binghai Liu,Jun Ding,Jiabao Yi,Jianhua Yin,Zhili Dong 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.52 No.5
This work presents a detailed study on the various magnetic anisotropies of NixCo1..xFe2O4 prepared by using a mechanochemical process. The results indicated that the magnetic anisotropy of NixCo1..xFe2O4 was strongly correlated with the Co2+ concentration. The Ni2+ substitution readily led to a decrease in the magnetocrystalline anisotropy and coercivity. While a large uniaxial anisotropy was induced in CoFe2O4 by magneto-annealing, the uniaxial anisotropy decreased with the Ni concentration in NixCo1..xFe2O4 and disappeared in the pure NiFe2O4. A short-time mechanical milling was found to signicantly increase the coercivity in NixCo1..xFe2O4 samples and high coercivities of 5.1 kOe and 2.8 kOe were achieved in the CoFe2O4 and the Ni0:5Co0:5Fe2O4 samples respectively. The microstructure and magnetic studies indicated that the milling-induced high coercivity could be ascribed to milling-induced stress anisotropy and to the pinning eects of defects. This work presents a detailed study on the various magnetic anisotropies of NixCo1..xFe2O4 prepared by using a mechanochemical process. The results indicated that the magnetic anisotropy of NixCo1..xFe2O4 was strongly correlated with the Co2+ concentration. The Ni2+ substitution readily led to a decrease in the magnetocrystalline anisotropy and coercivity. While a large uniaxial anisotropy was induced in CoFe2O4 by magneto-annealing, the uniaxial anisotropy decreased with the Ni concentration in NixCo1..xFe2O4 and disappeared in the pure NiFe2O4. A short-time mechanical milling was found to signicantly increase the coercivity in NixCo1..xFe2O4 samples and high coercivities of 5.1 kOe and 2.8 kOe were achieved in the CoFe2O4 and the Ni0:5Co0:5Fe2O4 samples respectively. The microstructure and magnetic studies indicated that the milling-induced high coercivity could be ascribed to milling-induced stress anisotropy and to the pinning eects of defects.
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