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      • KCI등재

        Teacher receptivity to system-wide curriculum reform in the initiation stage: a Chinese perspective

        Yun-peng Ma,Hong-biao Yin,Li-fang Tang,Li-yan Liu 서울대학교 교육연구소 2009 Asia Pacific Education Review Vol.10 No.3

        Few studies deal with teachers' receptivity in the initiation stage of educational change, especially in a non-western cultural context like Mainland China. This study aims at investigating teachers' receptivity to the system-wide curriculum reform of the senior secondary education in the initiation stage and understanding the factors influencing teachers' receptivity in Mainland China. Questionnaire survey with open-ended question (n = 763) is employed to explore teachers' receptivity in four selected experimental provinces, i.e., the first group of provinces which are selected by Ministry of Education to implement the curriculum reform. Results indicate teachers have positive attitudes and behavioral intentions toward promoting the curriculum reform of senior secondary education, and they consider the reform is valuable but difficult to carry out. The existing theoretical model can explain teachers' behavioral intentions quite well, but its predicting ability to teachers' general attitudes is limited, which indicates some new variables that need to be considered, too. Implications of this study and suggestions for future research are also discussed in the article.

      • KCI등재

        Studies of Thermo-electromagnetics Mechanisms Regulating a Direct/Hybrid Microwave Sintering of α and β-Aluminum Oxide: Kinetics of Densification and Influence of Magnetic Field

        Shuangjun Ma,Long Wang,Yun Peng Zhang,Nan Zou,Mouhamadou A. Diop 대한금속·재료학회 2023 METALS AND MATERIALS International Vol.29 No.9

        Most existing studies present microwaves as a heating technique that improves alumina sintering. However, the experimentaldevice limits have hampered the identification of the effects’ nature. Because of this, most of the studies in the literatureuse a phenomenological approach to characterize the microwave (MW) sintering technique, and there are few systematiccomparisons with standard sintering (ST). This work aims to directly and accurately compare the alumina sintering behaviorin a microwave (MW) and standard technique (ST) heating. The approach proposed in the present study depicts the electromagneticand radiation interactions with the aluminum oxides and investigates the α and β-alumina densification process. The direct and indirect sintering results in MW furnaces with a single-mode resonant cavity present the MW effects, suchas the electromagnetic field, to accelerate the alumina densification. For pure α-powders, the MW effects occur at the initialand intermediate sintering stages. The results show a diminution of the sintering driving force throughout the densificationprocess in a heating cavity. They seem to prevent obtaining a higher final density compared to ST sintering. In direct modesintering (DMS), the magnetic field accelerates the densification mechanisms and the surface scattering. At high temperaturesand densities, the ST driving force is also weakened, while in hybrid mode sintering, there is no degradation in the drivingforce, which remains stronger compared to DMS.

      • KCI등재

        Optimization of ultrasonic assisted membrane strategy for saponins from Gynostemma Pentaphyllum with response surface methodology

        Cunyu Li,Yun Ma,Xinglei Zhi,Guoping Peng 한국식품과학회 2023 Food Science and Biotechnology Vol.32 No.3

        Gynostemma pentaphyllum saponin has a variety of biological properties. Classic separation methods of saponin, such as resin absorption and preparative chromatography are limited by environmental pollution and high cost. In the study, ultrasonic assisted membrane separation was firstly used to purify saponin from Gynostemma pentaphyllum. Total proteins, polysaccharides, saponin, gypenoside A and rutin were selected as indexes to optimize the pretreatment and purification parameters by response surface methodology. The fitted models were significant (p < 0.05) and the optimal conditions were: (1) removing protein and polysaccharides by MWCO 10,000 Da, ultrasonic power 400 W and pH 7.8; (2) separation flavonoids from saponin by MWCO 1000 Da, ultrasonic power 300 W and pH 7.9. The difficulty in separating saponin from flavonoids was solved by releasing flavonoids from micelles with ultrasonic assisted membrane method. The saponin content in Gynostemma pentaphyllum extracts reached 82.81%, which was more than four times of that obtained with resin adsorption method. The protective effect of saponins on SH-SY5Y cells injury induced by H2O2 was better than that of Gynostemma pentaphyllum extracts. The study suggested that ultrasonic assisted membrane method would be widely applied in the preparation of food materials.

      • AIDS-Related Non-Hodgkin Lymphoma: Imaging Feature Analysis of 27 Cases and Correlation with Pathologic Findings

        Yang, Jun,Wang, Peng,Lv, Zhi-Bin,Wei, Lian-Gui,Xu, Yun-Liang,Zhou, An,Xu, Dong-Hai,Ma, Da-Qing Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.18

        Background: Some tumor types are related to HIV, including non-Hodgkin lymphoma (NHL). The morbidity and mortality of NHL has remained high, even after highly active antiretroviral therapy (HAART) was introduced. We collected cases of AIDS with NHL, and evaluated the imaging features and strategies for diagnosis. Materials and Methods: There were 27 patients with AIDS and tumors confirmed by pathology. There were 9 patients with Burkitt lymphoma, 16 with diffuse large B cell lymphomas (DLBCLs), and 2 with primary central nervous system (PCNS) lymphomas. All of the patients underwent a series of imaging studies. Three radiologists analyzed the images, and any disagreement was discussed until consensus was reached. Results: The radiologic manifestations of AIDS with NHL were mainly masses and lymphadenopathy, 3 patients having one mass and 12 two or more masses. 7 patients had lymphadenopathy in one site and 3patients had lymphadenopathy in two or more sites. Coarse mucosal folds, thickening of the gastrointestinal wall, and lumen narrowing were typical manifestations of NHL within the gastrointestinal tract. There were 4 patients with masses and 5 with lymphadenopathy inthe 9 with Burkitt lymphoma, and 11 patients with masses 5 with lymphadenopathy in the 16 with DLBCLs. Conclusion: NHL is a malignancy that usually occurs in patients with AIDS. Imaging is an important method by which to evaluate lesions, masses, and lymphadenopathy. Fine needle aspiration biopsy and stereotaxis biopsy are useful methods by which to diagnose NHL.

      • Diagnostic Potential of Strain Ratio Measurement and a 5 Point Scoring Method for Detection of Breast Cancer: Chinese Experience

        Parajuly, Shyam Sundar,Lan, Peng Yu,Yun, Ma Bu,Gang, Yang Zhi,Hua, Zhuang Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

        Aim: To evaluate the differential diagnostic potential of lesion stiffness assessed by the sonoelastographic strain index ratio (SR) and elastographic color scoring system (UE) for breast lesions. Materials and Methods: Three hundred and forty two breast masses (158 benign and 184 malignant) from 325 consecutive patients (mean age 44.2 years; range 16-81)who had been scheduled for a sonographically guided core biopsy were examined proposed by Itoh et al, with scoring 1-3=benign and 4-5=malignant. Strain and area ratios of each lesion were calculated within the same machine. Histological diagnosis was used as the reference standard. The area under the curve (AUC) and cut-off point were obtained by receiver operating curve and the cross table Fischer Test was carried out for assessing diagnostic value. Sensitivity, specificity, PPV, NPV, accuracy and false-discovery rates were compared. Results: The mean strain ratios for benign and malignant lesions were 1.87 and 7.9 respectively. (P<0.0001). When a cutoff point of 3.54 was used, SR had a sensitivity of 94.6%, a specificity 94.3%, a PPV of 95.1%, an NPV of 93.7% and an accuracy of 94.4%. The AUC values were 0.90 for the 5 point scoring system (UE) and 0.96 for the strain index ratio. The overall diagnostic performance was SR method was better (P<0.05). Conclusions: Strain ratio measurement could be another effective predictor in elastography imaging besides 5 the point scoring system for differential diagnosis of breast lesions.

      • KCI등재

        In Vitro Activity of Taurine-5-Bromosalicylaldehyde Schiff Base Against Planktonic and Biofilm Cultures of Methicillin-Resistant Staphylococcus aureus

        ( Ru Qiang Yuan ),( Yun Peng Diao ),( Wen Li Zhang ),( Yuan Lin ),( Shan Shan Huang ),( Houli Zhang ),( Li Ma ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.8

        Staphylococcus aureus is a major human pathogen, implicated in both community and hospital acquired infections. The therapy for methicillin-resistant Staphylococcus aureus (MRSA) infections is becoming more difficult because of multidrug resistance and strong biofilmforming properties. Schiff bases have attracted attention as promising antibacterial agents. In this study, we investigated the in vitro activity of taurine-5-bromosalicylaldehyde Schiff base (TBSSB) against MRSA. The minimum inhibitory concentrations (MIC) and minimum bactericidal concentration (MBC) were determined using a microtiter broth dilution method. TBSSB effectively inhibited planktonic MRSA, with an MIC of 32 μg/ml. The time-kill curve confirmed that TBSSB exhibited bactericidal activity against MRSA. TBSSB was also found to significantly inhibit MRSA biofilm formation at 24 h, especially at 1×MIC and sub-MIC levels. Furthermore, scanning electron microscopy and transmission electron microscopy showed remarkable morphological and ultrastructural changes on the MRSA cell surface, due to exposure to TBSSB. This study indicated that TBSSB may be an effective bactericidal agent against MRSA.

      • Carbon-supported Ni nanoparticles for efficient CO <sub>2</sub> electroreduction

        Jia, Mingwen,Choi, Changhyeok,Wu, Tai-Sing,Ma, Chen,Kang, Peng,Tao, Hengcong,Fan, Qun,Hong, Song,Liu, Shizhen,Soo, Yun-Liang,Jung, Yousung,Qiu, Jieshan,Sun, Zhenyu Royal Society of Chemistry 2018 Chemical Science Vol.9 No.47

        <▼1><P>Carbon-coated Ni nanoparticles supported on N-doped carbon enable efficient electroreduction of CO<SUB>2</SUB> to CO comparable to single Ni sites.</P></▼1><▼2><P>The development of highly selective, low cost, and energy-efficient electrocatalysts is crucial for CO<SUB>2</SUB> electrocatalysis to mitigate energy shortages and to lower the global carbon footprint. Herein, we first report that carbon-coated Ni nanoparticles supported on N-doped carbon enable efficient electroreduction of CO<SUB>2</SUB> to CO. In contrast to most previously reported Ni metal catalysts that resulted in severe hydrogen evolution during CO<SUB>2</SUB> conversion, the Ni particle catalyst here presents an unprecedented CO faradaic efficiency of approximately 94% at an overpotential of 0.59 V, even comparable to that of the best single Ni sites. The catalyst also affords a high CO partial current density and a large CO turnover frequency, reaching 22.7 mA cm<SUP>–2</SUP> and 697 h<SUP>–1</SUP> at –1.1 V (<I>versus</I> the reversible hydrogen electrode), respectively. Experiments combined with density functional theory calculations showed that the carbon layer coated on Ni and N-dopants in carbon material both play important roles in improving catalytic activity for electrochemical CO<SUB>2</SUB> reduction to CO by stabilizing *COOH without affecting the easy *CO desorption ability of the catalyst.</P></▼2>

      • KCI등재

        Preparation and Hydrogen Barrier Property of FexAly/Al/Al2O3 Composite Coating on X80 Steel Surface

        Bingying Wang,Xiaoyong Sun,Enyang Liu,Lin Liu,Wenjuan Ma,Yuze Shi,Peng Huang,Yun Luo 대한금속·재료학회 2024 METALS AND MATERIALS International Vol.30 No.1

        Hydrogen-induced embrittlement is a significant safety concern for steel pipelines used in the transmission of hydrogenblendednatural gas. To mitigate this issue, hydrogen barrier coatings can be applied to the surface of steel substrates toreduce hydrogen permeation. In this study, rare earth oxides were optimized via first-principles calculations to identify themost effective doping agents. Subsequently, a FexAly/Al/Al2O3 composite coating doped with La2O3and Ce2O3was successfullyapplied to the surface of X80 steel using hot-dip aluminum plating combined with anodic oxidation. The coatingwas characterized using various techniques, including SEM, EDS, XRD, XPS, and hydrogen permeation tests. The resultsdemonstrated that co-doping La2O3and Ce2O3resulted in a lower adsorption energy of Al2O3to hydrogen molecules, andimproved the surface quality of the aluminizing layer and the composite coating. Electrochemical hydrogen permeationtests showed that the FexAly/Al/Al2O3 composite coating significantly improved the hydrogen barrier property of X80 steel. The anodizing current density was found to have a significant effect on the coating's morphology, which in turn affected thehydrogen barrier property of the coating. The composite coating obtained at an anodizing current density of 2 A/dm2 wasuniform and dense, without noticeable defects, and exhibited the best hydrogen barrier property.

      • SCIESCOPUSKCI등재

        Analysis of the Genome Sequence of Strain GiC-126 of Gloeostereum incarnatum with Genetic Linkage Map

        ( Wan-zhu Jiang ),( Fang-jie Yao ),( Ming Fang ),( Li-xin Lu ),( You-min Zhang ),( Peng Wang ),( Jing-jing Meng ),( Jia Lu ),( Xiao-xu Ma ),( Qi He ),( Kai-sheng Shao ),( Asif Ali Khan ),( Yun-hui Wei 한국균학회 2021 Mycobiology Vol.49 No.4

        Gloeostereum incarnatum has edible and medicinal value and was first cultivated and domesticated in China. We sequenced the G. incarnatum monokaryotic strain GiC-126 on an Illumina HiSeq X Ten system and obtained a 34.52-Mb genome assembly sequence that encoded 16,895 predicted genes. We combined the GiC-126 genome with the published genome of G. incarnatum strain CCMJ2665 to construct a genetic linkage map (GiC-126 genome) that had 10 linkage groups (LGs), and the 15 assembly sequences of CCMJ2665 were integrated into 8 LGs. We identified 1912 simple sequence repeat (SSR) loci and detected 700 genes containing 768 SSRs in the genome; 65 and 100 of them were annotated with gene ontology (GO) terms and KEGG pathways, respectively. Carbohydrate-active enzymes (CAZymes) were identified in 20 fungal genomes and annotated; among them, 144 CAZymes were annotated in the GiC-126 genome. The A mating-type locus (MAT-A) of G. incarnatum was located on scaffold885 at 38.9 cM of LG1 and was flanked by two homeodomain (HD1) genes, mip and beta-fg. Fourteen segregation distortion markers were detected in the genetic linkage map, all of which were skewed toward the parent GiC-126. They formed three segregation distortion regions (SDR1-SDR3), and 22 predictive genes were found in scaffold1920 where three segregation distortion markers were located in SDR1. In this study, we corrected and updated the genomic information of G. incarnatum. Our results will provide a theoretical basis for fine gene mapping, functional gene cloning, and genetic breeding the follow-up of G. incarnatum.

      • Heat-Shock Protein 70 as a Tumor Antigen for in vitro Dendritic Cell Pulsing in Renal Cell Carcinoma Cases

        Meng, Fan-Dong,Sui, Cheng-Guang,Tian, Xin,Li, Yan,Yang, Chun-Ming,Ma, Ping,Liu, Yun-Peng,Jiang, You-Hong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

        Immunological functions of heat shock proteins (HSPs) have long been recognized. In this study we aimed to efficiently purify HSP70 from renal cell carcinoma and test it as a tumor antigen for pulsing dendritic cells in vitro. HSP70 was purified from renal cell carcinoma specimens by serial column chromatography on Con A-sepharose, PD-10, ADP-agarose and DEAE-cellulose, and finally subjected to fast protein liquid chromatography (FPLC). Dendritic cells derived from the adherent fraction of peripheral blood mononuclear cells were cultured in the presence of IL-4 and GM-CSF and exposed to tumor HSP70. After 24 hours, dendritic cells were phenotypically characterized by flow cytometry. T cells obtained from the non-adherent fraction of peripheral blood mononuclear cells were then co-cultured with HSP70-pulsed dendritic cells and after 3 days T cell cytotoxicity towards primary cultured renal cell carcinoma cells was examined by Cell Counting Kit-8 assay. Dendritic cells pulsed in vitro with tumor-derived HSP70 expressed higher levels of CD83, CD80, CD86 and HLA-DR maturation markers than those pulsed with tumor cell lysate and comparable to that of dendritic cells pulsed with tumor cell lysate plus TNF-${\alpha}$. Concomitantly, cytotoxic T-lymphocytes induced by HSP70-pulsed dendritic cells presented the highest cytotoxic activity. There were no significant differences when using homologous or autologous HSP70 as the tumor antigen. HSP70 can be efficiently purified by chromatography and induces in vitro dendritic cell maturation in the absence of TNF-${\alpha}$. Conspecific HSP70 may effectively be used as a tumor antigen to pulse dendritic cells in vitro.

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