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잣나무 (Pinus koraiensis) 목부의 추출성분
이학주,최윤정,최돈하,홍인표 한국목재공학회 2003 목재공학 Vol.31 No.5
잣나무 목부 에탄올 조추출물로부터 7종의 화합물을 단리하였으며, 기기분석 결과 flavonoids인 5-hydroxy-7-methoxyflavone을 비롯하여 chrysin, pinocembrin, pinobanksin, galangin 그리고 stilbenoids 화합물인 3-hydroxy-5-rnothoxystilbene과 pinosylvin으로 각각 동정되었다. Two stilbenoids and five flavonoids were isolated from wood of Pinus Roraiensis(Pinaceae). The chemical structures of isolated compounds were determined as : 5-hydroxy-7-methoxyflavone, chrysin, galangin, pinocembrin, pinobanksin, 3-hydroxy-5-methoxystilbene and pinosylvin on the basis of Mass and NMR spectroscopic data.
유색미에 관한 연구 : Ⅲ. 유색미 유망계통에 대한 주요 생육 특성
김광수,최윤표,김선택,최현구,정종태,김보경,유지홍,이희봉 충남대학교 농업과학연구소 2007 농업과학연구 Vol.34 No.2
국내외 유색미 수집종을 돌연변이원에 의해 유기된 우수 계통과 수집종간 상호교배에 의해 선발된 CNU 20계통을 파종하여 얻어진 주요 작물학적 특성을 살펴보면 다음과 같다. 1. 간장은 유색 메벼인 CNU126 계통이 대조품종인 동진벼와 같이 가장 컸고 메성인 CNU 128계통에서 가장 작았다. 2. 주당 분얼수는 CNU3, CNU50. CNU56, CNU112 계통에서 가장 많았고 대조품종과 CNU 128 계통에서 10개 미만으로 가장 적게 나타났다. 3. 수장은 육성 계통 중 CNU88 계통에서 가장 길었으나 대조구보다 짧고, 육성계통 중에서는 CNU 126 계통이 가장 짧았다. 4. 주당 영화수는 대조구인 동진벼보다 CNU50 계통에서 2배 이상 많았고, CNU158 계통에서 가장 적게 나타났다. 5. 천립중은 CNU113 계통에서 30g이상으로 대조구와 같이 가장 무거웠고, CNU128 계통에서 20g으로 가장 적었다. 6. 주당 수량은 대조구의 26.6g에 비해 CNU50, CNU112 계통에서 두배정도 높았고, CNU128, CNU158, CNU200 계통에서 가장 낮게 타나났다. Aims of this study were carried out to develop the useful lines induced from mutation and pedigree breeding methods among the collected genetic resources from national and domestic areas. In this study, Stem height of CNU126 line and check among them were high, while CNU128 was lower than other lines. Spiklet length of CNU88 was longer, but that of CNU126 was shorter than check. Number of spiklets per plant of CNU50 among lines have twice time than check. 1,000 grains weight of CNU113 was higher than check. In yield per plant, CNU50 and CNU112 were higher than check, Dongjinbyeo.
교잡종 찰옥수수에 대한 연구 III : Ⅲ. 국내 옥수수 유전자원 수집종에 대한 주요 특성 분포
서정은,주현민,최윤표,홍범용,조양희,주정일,지희정,이희봉 충남대학교 농업과학연구소 2007 농업과학연구 Vol.34 No.2
2006년 국내 각 지역으로부터 수집된 재래종옥수수 유전자원을 관행방법에 의해 파종하고 주요특성별로 분포도를 살펴본 결과는 다음과 같다. 1. 수집된 유전자원에 대한 발아율은 대부분 80∼100%이상의 분포를 보였으나, 일부 수집계통에는 30% 미만의 극히 저조한 발아율을 보였다. 2. 수집자원에 대한 초기생육을 살펴보면 극히 생육이 저조한 것이 40% 정도를 보였고, 극히 우수한 자원은 3%미만으로 나타났다. 3. 간장은 대부분이 150∼199cm범위에 55%가 분포하고 있었으나, l00cm이하가 5%, 250cm이상이 8%로 나타나 수집종간에 큰 차이를 보였다. 4. 주당 분얼수는 1개 미만이 40%의 분포를 보였으나, 일부 수집종에서 2 내지 3개의 분얼수를 보이는 계통이 확인되었다. 5. 개화소요일수는 61∼64일의 범위에서 40%, 57∼60일의 범위에서 30%의 분포를 보였으며, 특히 일부 수집종의 경우 55일 이하의 극조생종도 10% 정도의 분포를 보였다. 6. 이삭길이는 대부분 11∼15cm범위에 60%가 포함되어 있으나, 일부계통에서 5cm미만이 2%, 16∼20cm의 이삭길이도 10%가 분포하였다. Germination ratio on the 300 collected genetic resources showed 80 to 100 percentage, but those of some accessions were very low as below 30 percentage. Early growth phase of most of these lines were very poor while some collected lines were very vigor. Range of stem height showed from 150 to 199cm, but that of some accessions showed below 100cm as five percentage and some of them was over 250cm as eight percentage. Number of tillers per plant appeared less one but some collected lines have two to three tillers per plant. In days to tasseling, some accessions showed more four per plant. Ear length of these accession showed above 60 percentage as 11 to 15cm, while that of some collected lines showed over 10 percentage as 16 to 20cm.
Choi Jun-Pyo,Ayoub Ghazal,Ham Jarang,Huh Youngmin,Choi Seung Eun,Hwang Yu-Kyoung,Noh Ji Yun,Kim Sae-Hoon,Song Joon Young,Kim Eu Suk,Chang Yoon-Seok 대한면역학회 2023 Immune Network Vol.23 No.2
It has been reported that some exercise could enhance the anti-viral antibody titers after vaccination including influenza and coronavirus disease 2019 vaccines. We developed SAT-008, a novel digital device, consists of physical activities and activities related to the autonomic nervous system. We assessed the feasibility of SAT-008 to boost host immunity after an influenza vaccination by a randomized, open-label, and controlled study on adults administered influenza vaccines in the previous year. Among 32 participants, the SAT-008 showed a significant increase in the anti-influenza antibody titers assessed by hemagglutination-inhibition test against antigen subtype B Yamagata lineage after 4 wk of vaccination and subtype B Victoria lineage after 12 wk (p<0.05). There was no difference in the antibody titers against subtype “A.” The SAT-008 also showed significant increase in the plasma cytokine levels of IL-10, IL-1β, and IL-6 at weeks 4 and 12 after the vaccination (p<0.05). A new approach using the digital device may boost host immunity against virus via vaccine adjuvant-like effects.
Process Innovation Improves Trial Operation Efficiency
Choi, Yun Jung,Kim, Kyu-pyo,Park, Sumi,Park, MiYeon,Kim, Sulhwa,Kim, Younkyoung,Bae, Kyun-Seop,Beck, Sung-Ho,Choi, Ki-Eun,Chung, Jong Woo,Lim, Young–,Suk,Kim, Tae Won SAGE Publications 2016 Therapeutic innovation & regulatory science Vol.50 No.4
<P>Background: Despite the fact that unaddressed delays in clinical trial operation could severely compromise the overall effort invested, there seems to be a lack of concerted effort in reforming such delays. This study evaluated the composite effect of initiatives in reforming trial operation efficiency. Methods: A high-volume academic medical center in Korea has implemented various initiatives to improve the trial operation efficiency by expediting times from institutional review board (IRB) submission to approval, from IRB submission to trial open for subject enrollment, and from trial open to first patient-in. The initiatives include implementation of the protocol preliminary review, parallel processing of the clinical trial agreement review in line with the protocol submission to the IRB, and involvement of project manager for operational risk management. Times from IRB submission to approval, from IRB submission to trial open, and from trial open to first patient-in before and after implementation of initiatives were compared. Results: The median time required in IRB approval was meaningfully shorter in the postinitiative group (19 vs 14 days; P < .001). The median times from IRB submission to trial open for subject enrollment and from trial open to first patient-in were reduced significantly in the postinitiative group (trial open: 25 vs 18 days, P < .001; first patient-in: 111.5 vs 100 days, P = .014). Conclusions: The initiatives were effective in reforming trial operational efficiency. Additional studies to address the cause of operational delay and modifiable factors influencing subject enrollment are needed to further improve operational efficiency.</P>
찰성벼 CNU계통에 대한 질소 수준별 주요 수량 관련 형질
최윤표(Yun-Pyo Choi),차희정(Hui-Jeong Cha),복태규(Tae-Gyu Bok),나승연(Seung-Yeon Na),정종태(Jong-Tae Jeong),이희봉(Hee-Bong Lee) 충남대학교 농업과학연구소 2009 농업과학연구 Vol.36 No.2
CNU육성 찰벼 계통에 대해 질소 시비 수준을 달리하여 주요 작물학적 및 수량관련 형질을 살펴본 결과 다음과 같다. 공시된 벼품종의 간장은 유색찰벼인 경우 10a당 질소 7㎏ 수준이 9㎏보다 다소 크게 나타났고, 무색찰벼는 Aranghyangchal, Dongjinchal이 큰 반면에 기타 공시종은 9㎏수준에서 크게 나타났다. 주당 분얼수는 유색미인 경우 10a당 질소 9㎏ 처리가 7㎏보다 CNU 08-01, CNU 08-02에서 높게 나타났고, 대조품종은 두 처리 모두 같은 경향을 보였으며, 무색미는 9㎏처리에서 Dongjinchal이 높게 나타났다. 질소 수준별 등숙율은 유색미인 경우는 대체적으로 질소 7㎏ 수준에서 높게 나타난 반면, 무색미는 Dongjinchal, CNU 08-105계통을 제외한 CNU 08-101, Nunborachal, Aranghyangchal이 9㎏ 수준에서 다소 높게 나타났다. 천립중은 공시종 모두 질소 9㎏수준이 7㎏보다 대체적으로 높게 나타났고, 20주당 조곡 수량은 CNU계통의 경우 모두 7㎏보다 9㎏에서 수량 증가를 보였으나 대조 품종인 경우에는 Aranghyangchal을 제외하고는 대부분이 7㎏수준에서 높은 경향을 보였다. Objectives of this study was to find the effect on two different nitrogen levels about agricultural characteristics of CNU rice lines developed at Crop Genetics and Breeding Laboratory, Chungnam Nat'l Univ.. Materials used were two black and one white glutinous rice lines, which were transplanted by hand with 30 × 15 ㎝ at CNU paddy field on May 23, 2009. These lines was designed with two replication by two nitrogen levels as 7㎏ and 9㎏ per 10a. As the result; Culm length of all lines used were higher at 7㎏ than 9㎏ per 10a while panicle length was longer at 9㎏ nitrogen level. Tillers per plant of CNU 08-01 and CNU 08-02 lines except CNU 08-101 showed highly at 9㎏ level, but that of other leading varieties were not constant trends in spite of increasing nitrogen. Ripening ratio of CNU 08-01 and 08-02 lines were higher at 7㎏ but CNU 08-101 line was higher at 9㎏. 1,000 grain weight and unhulled rice yield per 20 plants in all CNU lines were highly appeared at 9㎏ levels per 10a.