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Mutual Funds Herding under Financial Crises : Evidence from Taiwan Stock Markets
Yu-Fen Chen,Sheng-Yung Yang,Fu-Lai Lin 한국재무학회 2012 한국재무학회 학술대회 Vol.2012 No.09
This paper intends to investigate herding behavior of mutual fund managers participated in Taiwan stock market, especially as they were facing the regional and global financial crises in 1997 and 2008. Furthermore, it identifies fund managers’ optimal choices of trading strategies as they are facing the shallow-dish characteristics in Taiwan stock market. The empirical results reveal that fund managers do herd as they are picking up their portfolios. Instead of pursuing stocks with high speculative intensity, mutual fund managers adhere to the prudent rule to trade. However, the trading styles are not robust during the period of 1997 Asian financial crisis.
Chen, Yu,Wu, Fen,Saito, Eiko,Lin, Yingsong,Song, Minkyo,Luu, Hung N.,Gupta, Prakash C.,Sawada, Norie,Tamakoshi, Akiko,Shu, Xiao-Ou,Koh, Woon-Puay,Xiang, Yong-Bing,Tomata, Yasutake,Sugiyama, Kemmyo,Par Springer-Verlag 2017 Diabetologia Vol.60 No.6
<P>Diabetes was associated with a 26% increased risk of death from any cancer in Asians. The pattern of associations with specific cancers suggests the need for better control (prevention, detection, management) of the growing epidemic of diabetes (as well as obesity), in order to reduce cancer mortality.</P>
Bayesian-theory-based Fast CU Size and Mode Decision Algorithm for 3D-HEVC Depth Video Inter-coding
( Fen Chen ),( Sheng Liu ),( Zongju Peng ),( Qingqing Hu ),( Gangyi Jiang ),( Mei Yu ) 한국인터넷정보학회 2018 KSII Transactions on Internet and Information Syst Vol.12 No.4
Multi-view video plus depth (MVD) is a mainstream format of 3D scene representation in free viewpoint video systems. The advanced 3D extension of the high efficiency video coding (3D-HEVC) standard introduces new prediction tools to improve the coding performance of depth video. However, the depth video in 3D-HEVC is time consuming. To reduce the complexity of the depth video inter coding, we propose a fast coding unit (CU) size and mode decision algorithm. First, an off-line trained Bayesian model is built which the feature vector contains the depth levels of the corresponding spatial, temporal, and inter-component (texture-depth) neighboring largest CUs (LCUs). Then, the model is used to predict the depth level of the current LCU, and terminate the CU recursive splitting process. Finally, the CU mode search process is early terminated by making use of the mode correlation of spatial, inter-component (texture-depth), and inter-view neighboring CUs. Compared to the 3D-HEVC reference software HTM-10.0, the proposed algorithm reduces the encoding time of depth video and the total encoding time by 65.03% and 41.04% on average, respectively, with negligible quality degradation of the synthesized virtual view.
Yu Xiao,Fen Li,Anyuan Zheng,Qibing Chen,Fuhai Chen,Xiang Cheng,Zezhang Tao 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.8
Even though nasopharyngeal carcinoma (NPC) is not common worldwide, it is a major public health burden in endemic areas. Distant metastasis often leads to a poor prognosis for NPC; therefore, new and effective anticancer strategies are needed. Ginkgolic acid (GA) is small-molecule compound existing in Ginkgo biloba that has various biologically relevant activities, including antitumor properties; however, its effects and mechanism of action in NPC are unknown. The effects of GA on NPC and such underlying mechanisms were investigated using 5–8F and CNE2 cells and NP69 human immortalized nasopharyngeal epithelial cells in this study. Moreover, the xenograft models were built to examine GA's effection in vivo. GA treatment decreased the survival and invasive capacity of 5–8F and CNE2 and induced their apoptosis, which varied with dose; this was accompanied by downregulation of B cell lymphoma (Bcl)2, upregulation of Bcl2-associated X protein, and activation of poly-ADP ribose polymerase, and caspase-9/-3. G0/G1 phase arrest was induced by GA in NPCs. It also reduced the expression of cyclin-dependent kinase 6 and its regulators cyclin D2 and cyclin D3. GA inhibited the activation of protein kinase B/nuclear factor signaling; this effect was potentiated with GA and 5-fluorouracil (5-FU), which also enhanced 5-FU-induced apoptosis. In summary, GA may be effective as an adjuvant to conventional chemotherapy drugs in preventing the progression of NPC.
Yu Wang,Pei-Sheng Lee,Yi-Fen Chen,Chi-Tang Ho,Min-Hsiung Pan 한국식품영양과학회 2016 Journal of medicinal food Vol.19 No.9
We reported previously that hydroxylated polymethoxyflavones (HPMFs) effectively suppressed obesity in high-fat-induced mouse. In this study, we further investigated the molecular mechanism of action of 5-hydroxy-3,6,7,8,3′,4′-hexamethoxyflavone (5-OH-HxMF), one of major HPMFs in orange peel. Treatment of 5-OH-HxMF effectively inhibited lipid accumulation by 55–60% in a dose-dependent manner. The 5-OH-HxMF attenuated adipogenesis through downregulating adipogenesis-related transcription factors such as peroxisome proliferator-activated receptor gamma (PPARγ) and CCAAT/enhancer-binding proteins (C/EBPs), as well as downstream target fatty acid synthase and acetyl-CoA carboxylase (ACC). 5-OH-HxMF activated adenosine monophosphate-activated protein kinase signaling and silent mating type information regulation 1 (SIRTUIN 1 or SIRT1) in 3T3-L1 adipocytes to decrease lipid accumulation. In addition, the inhibition rate of lipid accumulation was compared between 5-OH-HxMF and 3,5,6,7,8,3′,4′-heptamethoxyflavone (HpMF). 5-OH-HxMF inhibited lipid accumulation 15–20% more than HpMF did, indicating that hydroxyl group at position 5 can be a key factor in the suppression of adipogenesis.
A Study on the Development Strategy of the Taiwan Beauty SPA Industry
Hsin Fen Chien,Teng Tsai Tu,Chun Yu Chen 한국유통과학회 2017 KODISA ICBE (International Conference on Business Vol.2017 No.-
This study focuses on the future development strategy of Taiwan beauty SPA industry. The analysis is based on the PEST analysis of external environment, five forces analysis of internal industry, SWOT analysis of dealer K and in-depth interviews with senior executives of distributors. The results indicate that under the trend of the pursuit of health care, the products of the beauty industry are primarily healthy and environmentally friendly, naturally organic certificated, cosmetic beauty and natural non-toxic biotechnology products. In response to the advent of the era E, beauty SPA industry should make good use of digital platform marketing functions and establish beauty APP application software. At the same time, the beauty SPA industry can also use the e-commerce channel to carry out the business model of clicks and mortar to create greater economic benefits. The beauty SPA industry should integrate alliances with its peers to develop new customers and to innovate their revenue structure. Based on the results of this study, this research hopes to help the beauty SPA industry and individual companies to find the most suitable development strategies so as to enhance the competitiveness of the beauty SPA industry.
Gui-Fen Zhou,Xiao-Yan Dai,Chen-Huan Yu,Jie Fang 한국식품과학회 2013 Food Science and Biotechnology Vol.22 No.3
Danggui (Angelica sinensis Radix) in East Asia for its unique pleasant flavor is usually cooked before utilizing to enhance its tonic effect. To evaluate the quality and bioactivity changes, heat treatments were carried out at 250oC for 0-45 min. 5-Hydroxymaltol, 5-hydroxymethylfurfural,Z-ligustilide, and ferulic acid in aqueous extract of processed danggui (APD) were determined by HPLC while antihypertensive effects were studied after oral administration of APD (50 and 100 mg/kg) for 3 days in spontaneously hypertensive rats (SHR). Compared with aqueous extract of danggui (AD), contents of ferulic acid and Z-ligustilide in APD were significantly decreased but 5-hydroxymaltol and 5-hydroxymethylfurfural were increased. APD could lower blood pressures, plasma renin activities, and angiotensin II levels of SHR, but AD failed to do those. APD exhibited hypotensive effects by regulating renin-angiotensin system and may warrant further evaluation as a potential antihypertensive agent.
Yea-Chen Liu,Yu-Ying Hsiao,Kuo-Lung Ku,Hui-Fen Liao,Wei-Chun Chao 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.7
Macrophages play an indispensable role in the host immune defense. Macrophages can undergo polarization into classically (M1) and alternatively (M2) activated macrophages. M1 macrophages activate immune and inflammatory response, while M2 macrophages are involved in tissue remodeling. Mahonia oiwakensis (Mo) is a herbal medicine in Asia used for its anti-inflammatory and analgesic properties; however, the mechanism is unclear. This study analyzed the effect of Mo extracts and its effects on the polarization of both macrophage RAW264.7 cells and mouse splenic macrophages. Water (Mo-W) and EtOH extracts (Mo-E) did not change the viability of RAW264.7 cells, whereas Mo-E inhibited nitric oxide (NO) production. The major compounds, berberine and palmatine, decreased the viability and NO levels of cells. The secretion of inflammatory cytokines CXCL16, IL-6, L-selectin, MCP1, RANTES, and sTNF-R1 was downregulated, whereas the production of vascular endothelial growth factor (VEGF) was upregulated by Mo-E, berberine, and palmatine treatments. Mo-E, berberine, and palmatine stimulated the expression of macrophage CD68 and M2-type CD204 markers, decreased M1-mediated p-STAT1 and NF-κB, and increased M2-mediated p-STAT6 expression. Similar effects on M2 polarization were also observed in splenic macrophages from mice. In conclusion, Mo-E, berberine, and palmatine modulated macrophages through the suppression of M1-mediated inflammation and the recruitment of M2-mediated VEGF secretion and STAT6 expression.