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      • An Estimation Method of Consolidation and Settlement of Soil Mass in Dredger Fill Area Based on SBAS-InSAR

        ( Qing-bo Yu ),( Qing Wang ),( Xue-xin Yan ),( Tian-liang Yang ),( Meng Yao ),( Kai Zhou ),( Xin-lei Huang ),( Jian-ping Chen ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2

        The land subsidence poses a nonnegligible threat to production and life, especially in dredger fill area. The essence of land subsidence is soil consolidation. Better evaluation of the degree of soil consolidation presents significant progress for predicting land subsidence. In this study, SBAS-InSAR was conducted to Chenjia town, the typical dredger fill area in Chongming East Shoal, Shanghai. SAR data and precise Orbit data were collected from the ESA satellite Sentinel-1 in recent 2 years with approximately one month intervals. the relationship curve of cumulative subsidence with time is obtained after processing. On this basis, the final settlement and soil consolidation can be estimated by applying the method proposed by Professor Huang Wenxi of China. The results show that: The subsidence rate is faster than 20 mm/a; The estimated final settlement is 26.6-52.9 mm, and the corresponding consolidation degree is 54.6 % on average; Soil mass has not yet been fully consolidated and it still takes a long time to achieve stability. In conclusion, the method proposed in this study can provide a clearer understanding of the consolidation degree, and a new reference for the evaluation and prevention of land subsidence. Future research will focus on longer monitoring time to enrich and improve the method. Acknowledgements This work was financially supported by National Nature Science Foundation of China (Grant No: 41820104001, 41430642 and 41627801) and the Key Laboratory of Land Subsidence Monitoring and Prevention, Ministry of Land and Resources (Grant No. KLLSMP201801).

      • Poster Session : PS 0076 ; Cardiology : The Prevalence of Hyperuricemia among Patients with Essential Hypertension in Rural-Urban Fringe

        ( Huang Yu Qing ),( Feng Ying Qing ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: To understand the prevalence of hyperuricemia in patients with essential hypertension in rural-urban fringe zone. Methods: All participants were from this hypertension database, namely, Public welfare industry special scientifi c research projects: “to monitor the risk factors of cardiovascular disease and standardized management of hypertension “,that launched by Fuwai cardiovascular hospital and Guangdong general hospital took part in. Extracting the fasting blood uric acid, blood biochemical indicators for analysis,and make groups according to age and gender, and of all ages to analyze the prevalence of hyperuricemia, and compare the differences prevalence of men and women between group. Results: There were total of 3136 essential hypertension with data integrity,the mean value of uric acid was (382.32±104.72)umol/L,the number of hyperuricemia was 1429 with the prevalence of hyperuricemia was 45.6%; among which 1297 were male, the mean value of uric acid was (420.70 + 104.12) umol/L, 637 cases of hyperuricemia, the prevalence was 49.1%, female 1839 cases, 792 cases of hyperuricemia, the mean value of uric acid was (355.09 + 96.57) umol/L, the prevalence was 43.1%, and the prevalence of hyperuricemia with men were higher than women (p < 0.05). Conclusions: The prevalence of hyperuricemia among essential hypertension is very hgh, and the prevalence rate of male is slightly higher than female.

      • Mechanical Effect of Pre-consolidation Pressure of Structural Behavior Soil

        ( Qing Wang ),( Qing-bo Yu ),( Tian-liang Yang ),( Xin-lei Huang ),( Xue-xin Yan ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2

        Structural property of soil is a new concept studied in science and study of this issue is a new problem, which involves soil mechanical effect, mechanical variability, and engineering design. Soil such as saline soil, red soil, loess, Xiashu loess, soft soil, or solidified dredger fill, which had been studied in previous research by our research group, has high pre-consolidation pressure (Pc) and high over-consolidation ratio (OCR). Considering the needs of intensity determination in engineering design, soil structure force, structural strength and other issues of structural Soils were studied in this paper. By analyzing experimental data, affecting factors of pre-consolidation pressure (Pc) was discussed. A new cognition about pre-consolidation pressure (Pc), determination method of structural strength, and genetic mechanism of structural force were proposed in this paper. Soil mass structural behavior and the mechanical effect can be one of the important fields of soil structural quantitative research. Acknowledgements This work was financially supported by the Key Project for International (Regional) Cooperation and Communication by National Natural Science Foundation of China (Grant No. 41820104001), State Key Program of the National Natural Science Foundation of China (Grant No. 41430642), the Special Fund for Major Scientific Instruments of the National Natural Science Foundation of China (Grant No. 41627801), and the Key Laboratory of Land Subsidence Monitoring and Prevention, Ministry of Land and Resources (Grant No. KLLSMP201801).

      • KCI등재

        Lung-Targeting Delivery of Dexamethasone Acetate Loaded Solid Lipid Nanoparticles

        Qing-yu Xiang,Yuan Huang,Zhi-rong Zhang,Min-ting Wang,Fu Chen,Tao Gong,Yan-lin Jian 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.4

        The objective of the present study was to develop a novel solid lipid nanoparticle (SLN) for the lung-targeting delivery of dexamethasone acetate (DXM) by intravenous administration. DXM loaded SLN colloidal suspensions were prepared by the high pressure homogenization method. The mean particle size, drug loading capacity and drug entrapment efficiency (EE %) of SLNs were investigated. In vitro drug release was also determined. The biodistribution and lung-targeting efficiency of DXM-SLNs and DXM-solutions (DXM-sol) in mice after intravenous administration were studied using reversed-phase high-performance liquid chromatography (HPLC). The results (expressed as mean ± SD) showed that the DXM-SLNs had an average diameter of 552 ± 6.5 nm with a drug loading capacity of 8.79 ± 0.04% and an entrapment efficiency of 92.1 ± 0.41%. The in vitro drug release profile showed that the initial burst release of DXM from DXM-SLNs was about 68% during the first 2 h, and then the remaining drug was released gradually over the following 48 hours. The biodistribution of DXM-SLNs in mice was significantly different from that of DXM-sol. The concentration of DXM in the lung reached a maximum level at 0.5 h post DXM-SLNs injection. A 17.8-fold larger area under the curve of DXM-SLNs was achieved compared to that of DXM-sol. These results indicate that SLN may be promising lung-targeting drug carrier for lipophilic drugs such as DXM.

      • KCI등재

        Field-Emission Property of Self-Purification SiC/SiOx Coaxial Nanowires Synthesized via Direct Microwave Irradiation Using Iron-Containing Catalyst

        Qing Zhou,Yongzhi Yu,Shan Huang,Jiang Meng,Jigang Wang 대한금속·재료학회 2017 ELECTRONIC MATERIALS LETTERS Vol.13 No.4

        SiC/SiOx coaxial nanowires were rapidly synthesized via directmicrowave irradiation in low vacuum atmosphere. During the preparationprocess, only graphite, silicon, silicon dioxide powders were used as rawmaterials and iron-containing substance was employed as catalyst. Comprehensive characterizations were employed to investigate themicrostructure of the products. The results showed that a great quantityof coaxial nanowires with uniform sizes and high aspect ratio had beensuccessfully achieved. The coaxial nanowires consist of a silicon oxide(SiOx) shell and a β-phase silicon carbide (β-SiC) core that exhibited inspecial tube brush like. In additional, nearly all the products wereachieved in the statement of pure SiC/SiOx coaxial nanowires withoutthe existence of metallic catalyst, indicating that the self-removal of iron(Fe) catalyst should be occurred during the synthesis process. Photoluminescence (PL) spectral analysis result indicated that suchnovel SiC/SiOx coaxial nanowires exhibited significant blue-shift. Besides, the measurement results of field-emission (FE) demonstratedthat the SiC/SiOx coaxial nanowires had ultralow turn-on field andthreshold field with values of 0.2 and 2.1 V/μm, respectively. The heterojunctionstructure formed between SiOx shell and SiC core, lots ofemission sites, as well as clear tips of the nanowires were applied toexplain the excellent FE properties.

      • SCIESCOPUSKCI등재

        Comparison of Hybridization Behavior between Double and Single Strand of Targets and the Application of Asymmetric PCR Targets in cDNA Microarray

        ( Qing Wei ),( San Zhen Liu ),( Jian Feng Huang ),( Xue Ying Mao ),( Xiao Hui Chu ),( Yu Wang ),( Min Yan Qiu ),( Yu Min Mao ),( Yi Xie ),( Yao Li ) 생화학분자생물학회 2004 BMB Reports Vol.37 No.4

        Double stranded targets on the cDNA microarray contain representatives of both the coding and noncoding strands, which will introduce hybridization competition with probes. Here, the effect of double and single strands of targets on the signal intensity and the ratios of Cy5/Cy3 within the same slide were compared. The results show that single stranded targets can increase the hybridization efficiency without changing the Cy5/Cy3 ratio. Based on these results, a new strategy was established by generating cDNA targets with asymmetric PCR, instead of conventional PCR, to increase the sensitivity of the cDNA microarray. Furthermore, the feasibility of this approach was validated. The results indicate that the cDNA microarray system based on asymmetric PCR is more sensitive, with no decrease in the reliability and reproducibility as compared with that based on conventional symmetric PCR.

      • KCI등재
      • KCI등재

        Study of the Synthesis and Properties of Ir(III) Complexes Based on Phosphine Carbonylimide Derivative as Auxiliary Ligand

        Qing-Mei Guo,Guoli Huang,Xin-Ying Yin,Jian-Jian Bian,Xiao-Mei Li,Ming-Yu Teng 대한화학회 2020 Bulletin of the Korean Chemical Society Vol.41 No.12

        Three iridium complexes of (dfppy)2Ir(DAPB), (dfppy)2Ir(DAPB), and (dfppy)2Ir(DAPB) were synthesized by using phosphine carbonylimide derivative as auxiliary ligand and fluoro?/trifluoromethyl substituted 2-phenylpyridine derivatives as primary ligands. Their quantum efficiency range from 19.4% to 38.5%, and show strong rigidochromic effect. The maximum emission wavelengths of solid-state fluorescence have remarkable red shifts from 39 to 55?nm compared with these in CH2Cl2.

      • KCI등재

        Dynamic and Damage Characteristics of Mortar Composite under Impact Load

        Qing Li,Tong-de Zhao,Chen Huang,Bing-bing Yu,Zheng-Hua Gao,Kai Wang 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.3

        In the process of underground construction, it is common to spray concrete on the working surface, which will form a concrete-rock composite structure, to achieve the expected reinforcement effect. Compared with pure concrete or rock structures, composite structures have different mechanical properties, energy evolution and damage characteristics. Understanding the dynamic mechanics and damage characteristics of composite structures under impact loads is important to the safety of underground engineering construction. First, dynamic compression tests on different grades of mortar-sandstone composite specimens were carried out by using a Hopkinson pressure bar system to discuss the effect of impact velocities on the mechanical properties and failure modes of composite specimens. The results show that the dynamic peak stress, strain energy density and fragmentation block of the mortar-sandstone composite have an obvious strain rate effect. With an increase in impact velocity, the internal cracks of the sample do not have sufficient time to expand, and the energy absorbed by the sample leads to the continuous initiation of new cracks in the sample, resulting in an increasing damage degree of composite specimens. The increase in mortar strength can significantly increase the peak stress, improve the load-bearing capacity of the sample, and reduce the degree of sample damage. At the same impact velocity, the fragmentation degree of the mortar sample is more severe than that of sandstone, and the mortar sample is broken into powder debris, while the sandstone is broken into fragments. In addition, according to the failure properties of the composite sample, the mortar and sandstone samples are described by different damage models, and the dynamic damage constitutive model of the mortar-sandstone composite is established based on the overlay principle. The dynamic test results were fitted. The research shows that the fitting curves of the model are well fitted with the test curves and that the model accurately reflects the changes in the mechanical parameters of the composite specimens.

      • KCI등재

        The Mechanism of Chronic Alcoholism-mediated Impairment in Traumatic Brain Injury

        ( Qing Song Huang ),( Hong Zhi Li ),( Hong Mei Chen ),( Yu Fang Pan ) 조선대학교 공학기술연구원 2013 공학기술논문지 Vol.6 No.1

        Alcohol-related traumatic brain injury (TBI) is a common condition in medical and forensic practice and results in high pre-hospital mortality. However, the related mechanism is still unclear. Herein, we establish a chronic alcoholism model of rats, and the chronic alcoholism rats showed an axonal degeneration and a decrease in the numerical density of synapses (p<0.01). Moreover, these rats also showed a compensatory increase in PSD-95 expression (p<0.01). Compared with chronic alcoholism rats, the EtOH-TBI rats group showed high mortality (50%, p<0.01), inhibition of respiration before death, severe axonal injury and decrease in PSD-95 expression (p<0.05). So, we concluded that chronic alcoholism can induce significant synapse loss and axonal impairment in the medulla oblongata and render the brain more susceptible to TBI. The synergistic effect of chronic alcoholism and TBI induces significant synapse and axon impairment and contributed to high mortality.

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