Add-on Effect and Safety of Pharmacopuncture Therapy in the Treatment of Patients with Lumbar Spinal Stenosis

Oh Yoona,Han Chang-Hyun,Kim Yeonhak,Kim Jihun,Yang Changsop,Choi Young Eun,Kang Byoung-Kab,Yang Gi Young,Lee Byung Ryul,Kim Eunseok 사단법인약침학회 2023 Journal of Acupuncture & Meridian Studies Vol.16 No.1

Background: Recently, Korean Medicine treatment with pharmacopuncture therapy (PPT) has been increasingly used in clinical practice to improve symptoms in patients with lumbar spinal stenosis (LSS). The aim of this study is to evaluate the effectiveness and safety of PPT in addition to conventional Korean Medicine treatment (CKMT) for the treatment of patients with LSS, compared with CKMT alone. Methods: This study is designed as a pragmatic, randomized, two-armed, parallel, stratified (by sex), controlled pilot trial. Forty patients diagnosed with LSS will be randomly allocated to the PPT + CKMT group or the CKMT group. Patients in the two groups will receive treatment two times weekly for 5 weeks. The primary outcome will be the mean change in the 100-mm visual analog scale score from the baseline to the end of treatment (week 5). The secondary outcomes will include the clinically important difference, Zurich Claudication Questionnaire score, self-reported walking capacity, Modified–Modified Schober test, EuroQol 5-dimension 5-level questionnaire, and Patients’ Global Impression of Change. Adverse events will be assessed at each visit. Discussion: The results of this study will provide meaningful data to evaluate the add-on effect and safety of PPT in the medical care of patients with LSS.

단미 한약과 합성 혈압약의 상호작용

오유나 ( Yoona Oh ),이홍범 ( Hongbum Lee ),김형우 ( Hyungwoo Kim ) 대한본초학회 2018 大韓本草學會誌 Vol.33 No.6

Objective : Many patients take antihypertensive drugs as well as herbal medicines at the same time in order to treat other symptoms or to keep their well-being. In this study, interactions between herbal medicines and synthetic antihypertensive drugs were analyzed. Methods : To investigate the interaction between herbal medicines and synthetic antihypertensive drugs, three electronic databases, including OASIS, Mediline and Sciencedirect were searched. Experimental and clinical studies on the interaction between herbal medicines and antihypertensive drugs were independently reviewed and included. Results : Analyzing selected studies, twenty herbs were found to interact with antihypertensive drugs. Herbs found to increase the antihypertensive effect were Panax ginseng, Carthamus tinctorius, Magnolia officinalis, Silybum marianum, Scutellaria baicalensis, Schisandra chinensis, Sophora flavescens, Piper nigrum, Curcuma longa, Ginkgo biloba, Juncus effuses and Hydrastis canadensis . In contrast, Commiphora myrrha, Rhodiola rosea, Hypericum perforatum, Eurycoma longifolia, and Daturae metel were found to inhibit the antihypertensive effect. Stephania tetrandra could increase or decrease the effect depending on the type of antihypertensive drug. Epedria sínica was suspected of pharmacodynamic interaction with antihypertensive drug. Glycyrrhiza uralensis has been reported to have serious side effects in combination with antihypertensive drugs. Conclusion : These results imply that when used in combination with herbal medicines and synthetic antihypertensive drugs, proper doses and herbs which are to avoid need to be informed to the patients. Despite concerns about interactions between herbal medicines and synthetic drugs, related research is very limited. More systematic researches are needed to give information on patient safety as well as to guide clinical practice.

시맨틱 위치기반서비스에서 프라이버시 보호를 위한 개인화 클로킹 생성 기법

오유나(Yoona Oh),박석(Seog Park) 한국정보과학회 2013 한국정보과학회 학술발표논문집 Vol.2013 No.11

A study on guideline for effective operation and safety management of air dome-typed landfill facilities

Yoona Cho,Namil Um,Jungkeun Oh,Youngjun Kim,Kiheon Kim,Sunkyoung Shin 한국분석과학회 2017 학술대회논문집 Vol.2017 No.11

Self-assembly of fluorescent and magnetic Fe₃O₄@coordination polymer nanochains

Kim, Yoona,Choi, Young Soo,Lee, Hee Jung,Yoon, Hayoung,Kim, Young Keun,Oh, Moonhyun The Royal Society of Chemistry 2014 Chemical communications Vol.50 No.57

<P>Fluorescent and magnetic Fe<SUB>3</SUB>O<SUB>4</SUB>@coordination polymer (Fe<SUB>3</SUB>O<SUB>4</SUB>@CP) nanochains are synthesized <I>via</I> a simple one-pot solvothermal reaction of magnetite (Fe<SUB>3</SUB>O<SUB>4</SUB>) and coordination polymer precursors in the presence of an external magnetic field. The shell thickness within Fe<SUB>3</SUB>O<SUB>4</SUB>@CPs was easily regulated by varying the amounts of coordination polymer precursors used during the reaction.</P> <P>Graphic Abstract</P><P>Fluorescent and magnetic Fe<SUB>3</SUB>O<SUB>4</SUB>@coordination polymer nanochains are synthesized <I>via</I> a simple one-pot solvothermal reaction of Fe<SUB>3</SUB>O<SUB>4</SUB> nanoclusters and coordination polymer precursors in the presence of an external magnetic field. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c4cc03217a'> </P>

잠재프로파일 분석을 이용한 청소년의 팬덤 활동 유형 분류 및 학업태도의 차이

오현정 ( Oh Hyunjung ),장유나 ( Jang Yoona ),홍세희 ( Hong Sehee ) 충남대학교 교육연구소 2020 교육연구논총 Vol.41 No.4

본 연구는 잠재프로파일 분석을 이용하여, 청소년의 팬덤 활동 잠재계층을 분류하고, 이에 영향을 미치는 요인 및 학업태도의 차이를 알아보고자 하였다. 연구대상은 한국아동·청소년 패널조사 2018의 1차년도 중학생 조사대상자 중 좋아하는 연예인이나 운동선수가 있다고 응답한 학생 1,547명이다. 연구 결과는 다음과 같다. 첫째, 청소년의 팬덤 활동은 소극적 활동 집단, 온라인 활동 집단, 물품 구매 활동 집단, 서포트 활동 집단으로 분류되었다. 둘째, 각 계층에 대해 성별과 거주지, 친구 관계의 영향을 살펴보았을 때, 성별과 친구 관계가 유의하였다. 셋째, 잠재계층에 대한 결과변수로서 학업태도를 학업 열의(헌신, 활기, 효능감, 몰두)와 학업 무기력(통제신념 결여, 학습동기 결여, 긍정정서 결여, 능동수행 결여)으로 나누어 살펴보았을 때, 활기, 학습동기 결여, 긍정정서 결여에서 유의한 계층 간 차이가 있었다. 본 연구는 청소년의 팬덤 활동에 대한 응답을 통해 잠재계층을 구분하여, 팬덤 활동 유형에 대한 이해를 돕고자 하였으며, 유형을 구분하지 않거나 자의적으로 구분한 기존 연구의 한계를 극복하고, 팬덤 활동의 학업태도에 대한 긍정적·부정적 측면을 동시에 알아보았다는 의의가 있다. The purposes of this study are to classify fandom activities of adolescents by latent profile analysis and to identify determinants and consequences of the latent profiles. The subjects of the study are 1,547 middle-school student subjects of the first survey of the 'Korean Children and Youth Panel Survey 2018' who responded to questions about whether they have favorite entertainers or athletes. Results are as follows. First, youth's fandom activities were classified into four groups: 'passive activity group', 'online activity group', 'product purchase activity group', and 'support activity group'. Second, when examining the effects of gender, residence, and friend relationship, gender and friend relationship were significant in determining the latent profiles. Third, among the academic attitude variables as outcome variables, lack of vitality, learning motivation, and affirmation showed significant differences across the latent profiles. This study made contributions to identifying the types of fandom activities of adolescents by dividing latent profiles and thus overcoming the limitations of existing studies that did not distinguish types of fandom activities or classified them arbitrarily.

양안 수직근육전이술로 치유된 양안 듀안안구후퇴증후군 1예

조윤애,오인경,Yoonae A,Cho,In Kyung Oh 대한안과학회 2006 대한안과학회지 Vol.47 No.6

Purpose: To report a male infant with bilateral Duane`s retraction syndrome treated with bilateral horizontal transpositions of vertical recti to the lateral rectus muscle. Methods: An 8-month-old boy showed bilateral Duane`s retraction syndrome with esotropia of 45PD, severe limitation of abduction (-4 and -3.5 in each eye) and mild globe retraction in both eyes. It was assumed that he inherited the condition from his father through an autosomal dominant pattern. His father showed esotropia of 25PD with -4 limitation of abduction in the left eye and a left head-turn of 10。. He also had +2 globe retraction, +1 upshoot and +2 downshoot in adduction of the left eye. Transposition of two vertical recti to the lateral rectus muscle was performed in both eyes of the boy. Results: Nine months after surgery, the boy had achieved a microesotropia of 6PD in primary gaze with stereopsis of 3000 seconds of arc and considerable improvement in abduction (-2, -1.5 in each eye). The amount of correction of esodeviation was 39PD. This favorable state was maintained at follow-up 3.5 years after surgery. Conclusions: An 8-month-old boy who had esotropia of 45PD caused by bilateral Duane`s retraction syndrome, underwent bilateral horizontal transpositions of vertical recti to the lateral rectus muscle. He achieved a microesotropia of 6PD in primary gaze and considerable improvement of abduction with only mild eyeball retraction.

성장혼합모형을 적용한 다문화 청소년의 사회적 위축 변화 유형화 및 영향요인 검증

장유나 ( Jang Yoona ),오현정 ( Oh Hyunjung ),안소영 ( Ahn Soyoung ),홍세희 ( Hong Sehee ) 안암교육학회 2020 한국교육학연구 Vol.26 No.4

본 연구는 다문화 청소년의 사회적 위축의 종단적 변화 양상을 유형화하고, 이에 영향을 줄 수 있는 변인들을 살펴보고자 하였다. 이를 위해 한국청소년정책연구원의 다문화청소년패널조사 2차년도(초5)부터 6차년도 (중3)까지의 자료를 사용하였으며, 사회적 위축 변화에 적합한 변화함수를 추정하여 이를 적용한 잠재계층을 분류하고, 3단계 접근법(3-step approach)을 활용하여 이와 관련된 영향요인의 유의성을 검증하였다. 분석 결과, 다문화 청소년의 사회적 위축의 종단적 변화에는 2차 함수 모형이 적합한 것으로 나타났으며, 이를 적용한 잠재계층은 ‘저수준 상승 집단’, ‘위축 급변 집단’, ‘고수준 하향 집단’, ‘중상 보편 집단’, ‘중하 보편 집단’의 5개 집단으로 분류되었다. 영향요인의 검증에서는 사회적 위축과 관련 있는 성별, 한국어 능력, 친구관계, 교사관계, 학습활동, 거주 지역의 영향을 분석하였으며, 집단 대비에 따라 달랐지만, 대체로 성별이 중요한 영향을 미치는 것으로 나타났고, 위축 급변 집단에 대해서는 유의미한 요인을 찾을 수 없었다. 본 연구는 다문화 청소년의 사회적 위축에 대해 종단적으로 분석하여, 이들의 상황에 대한 정확한 이해를 돕고자 하였다. 선행연구에서 공통적으로 나타났던 부정적인 결과에 비해, 본 연구에서는 70%가 넘는 다문화 청소년의 사회적 위축이 평균 수준에서 안정적으로 유지되는 것으로 나타나 새로운 결론을 제기했다는 의의가 있다. 다만, 4.7%의 위축 급변 집단에 대해서는 후속 연구가 필요한 것으로 사료된다. This study aimed to identify subtypes of eventual changes in social withdrawal of multicultural youths and examine their determinants. For the purposes, growth mixture models were applied to the data from the second to sixth waves of the Multicultural Youth Panel Survey of the Korea Youth Policy Institute. Based on the mixture models, change patterns in social withdrawal were classified and determinants of the patterns were tested using the three-step approach. Results shows that quadratic function was found to be suitable for the longitudinal changes in social withdrawal of multicultural youth, and the change patterns were classified into latent classes: ‘low-level rising group’, ‘rapid change group’, ‘high-level downward group’, ‘medium-level universal group’ and ‘medium-low universal group’. Further, the effects of gender, Korean language ability, friend relationship, teacher relationship, learning activity, and residential area on the latent classes were analyzed. Gender generally showed important effects on differentiating the classes although the gender effects differed depending on class comparisons. However, no significant factors were found for ‘rapid change group’. This study sought to help people understand longitudinal patterns in the social withdrawal of multicultural youths. Contrary to negative results found in previous studies, it is meaningful that more than 70% of multicultural youth's social withdrawal was found to remain stable at the average level, bringing up a new conclusion. However, follow-up studies are necessary for the 4.7 percent ‘rapid change group’.

Common data model-based real-world data for practical clinical practice guidelines: clinical pharmacology perspectives

Yoomin Jeon,Yoona Choi,김혜선,SeonYeong Oh,Howard Lee 대한임상약리학회 2020 Translational and Clinical Pharmacology Vol.28 No.2

네트워크 분석을 활용한 국내 대학원 교육학과 세부전공 분석

장유나 ( Jang Yoona ),강윤경 ( Kang Younkyung ),배상영 ( Bae Sangyoung ),오현정 ( Oh Hyunjung ),홍세희 ( Hong Sehee ) 인하대학교 교육연구소 2020 교육문화연구 Vol.26 No.4

본 연구는 국내 일반대학원 교육학과 전공 개설 현황을 탐색하고자 하였다. 이를 위해, 2020년 5월부터 6월까지 전국 대학의 일반대학원 교육학과 내 설치 전공을 수집하여 네트워크 분석을 시행하였으며, 대학정보를 공시하는 대학알리미 사이트에서 일반대학원 교육학과가 개설된 학교를 파악한 후, 각 학교 홈페이지와 입시요강을 참고하여 학교별 개설 전공 자료를 수집하였다. 연구 결과, 연결중심성과 근접중심성 측면에서 교육행정 전공이 가장 높게 나타났고, 교육공학, 교육심리, 교육상담, 교육과정, 평생교육 등이 뒤를 이었다. 매개중심성 측면에서는 평생교육 전공이 가장 높게 나타났고, 교육행정, 교육상담, 교육심리, 교육공학, 교육철학 등이 뒤를 이었다. 응집성 분석에서는 전공의 유사성으로 집단이 구별되기보다는 상대적으로 많은 대학에서 설치된 전공과 그렇지 않은 전공으로 구별되는 특징이 있었으며, 구조적 공백에는 고등교육 전공이 위치하는 것으로 나타났다. 본 연구는 국내 교육학과 전공 개설현황을 네트워크 분석으로 시각화하여 각 분석에서 나타난 특징을 해석하였으며, 방법론적으로는 연구 동향 분석에만 주로 사용되어 온 키워드 네트워크 분석의 범위를 확장하였다는 의의가 있다. This study aimed to explore the current status of graduate majors in the department of education in Korea. For the purpose, network analysis was conducted using information on graduate major openings in education nationwide. Results showed that education administration major was the highest in terms of degree centrality and closeness centrality, followed by educational technology, education psychology, education counseling, and curriculum. In terms of betweenness-centrality, lifelong education was the highest, followed by educational administration, educational counseling, educational psychology, and educational technology. In cohesive analysis, majors were distinguished depending o n h ow much commonly installed in many universities, rather than depending on how much similar. Higher education majors were located in structural holes. This study analyzed and visualized the current status of majors in the department of education in Korea using network analysis, and interpreted the characteristics of each network analysis. In methodology, it is meaningful that this study has expanded scopes of keyword network analysis, which has been mainly used for research trend analysis.