소상공인 협업화 지원 정책의 성공요인 인식 수준

서용성(Suh, Yongsung),오상영(Oh, Sang-Young) 한국산학기술학회 2014 한국산학기술학회논문지 Vol.15 No.11

본 연구는 정부의 소상공인 협업화 지원 사업에 참여하는 228 협업체를 대상으로 5개의 협업화 지원 성공 요인의 인식 수준을 조사하였다. 각 요인의 문항에 대한 목표중요도, 중요성 인식 단계, 현재 우려 수준에 대한 인식을 측정하였다. 기존의 연구 결과를 이용하여 각 요인의 성숙도, 문항별 성숙예측시간과 성숙도를 분석하였다. 선행 연구의 결과와 본 연구의 결과를 비교하고, 지원 사업의 시행 전후의 인식 변화를 분석하였다. 이러한 비교분석은 소상공인의 협업화 사업을 지원하는 정부의 정책에 반영될 수 있을 것이다. 정부의 지원 정책은 소상공인 협업화에 긍정적인 영향을 주었지만, 협업체들은 정부의 각종 지원의 감소를 우려하고 있다. 이러한 우려를 해소하기 위해 정부 정책은 협업체에 대하여 단발성이 아닌 성공시점까지 지속적 수행되어야 할 것이다. In this paper, 228 cooperations supported by government were surveyed on the cognition levels of 5 factors for successful policies that support small business cooperation. Goal importance, awareness stage of importance, and current concerning level were scored to each question of factors. Using the results of previous studies, the maturity of each success factor, and the forecast time to mature and maturity of each question were analyzed. The results were compared with the results of a study precedent. Moreover, the changes in the participants' recognition levels were reviewed between before and after government's support. These comparative studies reflect government policies. Despite the government's supporting policies aided on building cooperation positively, the participants still worry about the decreasing government support. To allay these concerns, government policies should be implemented continuously to promote cooperation rather than a one-time support.

Graphene quantum dots as a highly efficient solution-processed charge trapping medium for organic nano-floating gate memory

Ji, Yongsung,Kim, Juhan,Cha, An-Na,Lee, Sang-A,Lee, Myung Woo,Suh, Jung Sang,Bae, Sukang,Moon, Byung Joon,Lee, Sang Hyun,Lee, Dong Su,Wang, Gunuk,Kim, Tae-Wook IOP 2016 Nanotechnology Vol.27 No.14

<P>A highly efficient solution-processible charge trapping medium is a prerequisite to developing high-performance organic nano-floating gate memory (NFGM) devices. Although several candidates for the charge trapping layer have been proposed for organic memory, a method for significantly increasing the density of stored charges in nanoscale layers remains a considerable challenge. Here, solution-processible graphene quantum dots (GQDs) were prepared by a modified thermal plasma jet method; the GQDs were mostly composed of carbon without any serious oxidation, which was confirmed by x-ray photoelectron spectroscopy. These GQDs have multiple energy levels because of their size distribution, and they can be effectively utilized as charge trapping media for organic NFGM applications. The NFGM device exhibited excellent reversible switching characteristics, with an on/off current ratio greater than 10<SUP>6</SUP>, a stable retention time of 10<SUP>4</SUP> s and reliable cycling endurance over 100 cycles. In particular, we estimated that the GQDs layer trapped ∼7.2?×?10<SUP>12</SUP> cm<SUP>−2</SUP> charges per unit area, which is a much higher density than those of other solution-processible nanomaterials, suggesting that the GQDs layer holds promise as a highly efficient nanoscale charge trapping material.</P>

Clinical Impact of Beta Blockers in Patients with Myocardial Infarction from the Korean National Health Insurance Database

Hoyoun Won,Yongsung Suh,Gwang Sil Kim,Young-Guk Ko,Myeong-Ki Hong 대한심장학회 2020 Korean Circulation Journal Vol.50 No.6

Background and Objectives: Whether beta blockers favorably impact the clinical outcome in patients with acute myocardial infarction (AMI) remains in debate. We investigated the impact of beta blocker on major clinical outcomes during 2 years after percutaneous coronary intervention (PCI) in patients with AMI. Methods: All patients with the first AMI treated with PCI for the period of 2005 to 2014 from the Korean National Health Insurance Service claims database were enrolled. We defined the regular user as medication possession ratio (MPR) ≥80% and non-user as MPR=0%. We compared the occurrence of all cause death, myocardial infarction (MI) and stroke according to adherence of beta-blockers. A 1:1 propensity score-matching was conducted to adjust for between-group differences. Results: We identified a total 81,752 patients with met eligible criteria. At discharge, 63,885 (78%) patients were prescribed beta blockers. For 2 years follow up period, regular users were 53,991 (66%) patients, non-users were 10,991 (13%). In the propensity score matched population, regular use of beta blocker was associated with a 36% reduced risk of composite adverse events (all death, MI or stroke) (hazard ratio [HR], 0.636; 95% confidence interval [CI], 0.555–0.728; p<0.001). Compared to no use of beta blocker, regular use significantly reduced all death (HR, 0.736; 95% CI, 0.668–0.812; p<0.001), MI (HR, 0.729; 95% CI, 0.611–0.803; p<0.001) and stroke (HR, 0.717; 95% CI, 0.650–0.791; p<0.001). Conclusions: Prescription of beta blocker in patients with AMI after PCI was sequentially increased. Continuous regular use of beta blocker for 2 years after AMI reduced major adverse events compared to no use of beta blocker.

S-300 Could Population Based Biennial Health Screening Prevent Cardiovascular disease?

( Yong-hwan Jung ),( Yongsung Suh ),( Hyun-jin Kim ),( Hyong-bok Park ),( Tae-young Choi ),( Eui-seok Hwang ),( Deok-kyu Cho ) 대한내과학회 2016 대한내과학회 추계학술대회 Vol.2016 No.1

Could Population Based Biennial Health Screening Prevent Cardiovascular disease in General Population without Previous Cardiovascular Disease? Introduction: There is no data on whether or not biennial national health screening service in Korea could prevent cardiovascular disease in the real clinical field. Method:From national health insurance sample cohort, we enrolled a total of 299,597 survivors without previous cardiovascular disease at 1st Jan. 2010. We dividedall population into irregular (<2) or regular (>=2) screening group according to the number of national health screening service usage from 2006 to 2009. We compared the hard atherosclerotic cardiovascular disease (ASCVD) free survival for 4 years. The definition of hard ASCVD was the composite of myocardial infarction (KCD code I21~23), all stroke (I60~64) and coronary heart disease death (I20~25). Result:Risk factors such as hypertension (13.3 vs. 12.1% p<0.001), hyperlipidemia (12.6 vs. 10.6% p<0.001) and DM (6.6 vs. 6.4%, p=0.038) had been more frequently detected inregular screening group during screening period. Regular screening group has reduced future hard ASCVD events compared with irregular group after controlling confounding factors including age, gender, household income, residential area and risk factors. (HR 0.746 [95%CI 0.706-0.788], p<0.001) Conclusions: The regular usage of national health screening service was associated with reduced future hard ASCVD events in general population without previous cardiovascular disease.

Ticagrelor Monotherapy After 3-Month Dual Antiplatelet Therapy in Acute Coronary Syndrome by High Bleeding Risk: The Subanalysis From the TICO Trial

Yong-Joon Lee,Yongsung Suh,Jung-Sun Kim,Yun-Hyeong Cho,Kyeong Ho Yun,Yong Hoon Kim,Jae Young Cho,Ae-Young Her,Sungsoo Cho,Dong Woon Jeon,Sang-Yong Yoo,Deok-Kyu Cho,Bum-Kee Hong,Hyuckmoon Kwon,Sung-Jin 대한심장학회 2022 Korean Circulation Journal Vol.52 No.4

Background and Objectives: Identifying patients with high bleeding risk (HBR) is important when making decisions for antiplatelet therapy strategy. This study evaluated the impact of ticagrelor monotherapy after 3-month dual antiplatelet therapy (DAPT) according to HBR in acute coronary syndrome (ACS) patients treated with drug eluting stents (DESs). Methods: In this post-hoc analysis of the TICO trial, HBR was defined by 2 approaches: meeting Academic Research Consortium for HBR (ARC-HBR) criteria or Predicting Bleeding Complications in Patients Undergoing Stent Implantation and Subsequent DAPT (PRECISE-DAPT) score ≥25. The primary outcome was a 3–12 months net adverse clinical event (composite of major bleeding and adverse cardiac and cerebrovascular events). Results: Of the 2,980 patients without adverse events during the first 3 months after DES implantation, 453 (15.2%) were HBR by ARC-HBR criteria and 504 (16.9%) were HBR by PRECISE-DAPT score. The primary outcome rate was higher in HBR versus non-HBR patients (by ARC-HBR criteria: hazard ratio [HR], 2.87; 95% confidence interval [CI], 1.76–4.69; p<0.001; by PRECISE-DAPT score: HR, 3.09; 95% CI, 1.92–4.98; p<0.001). Ticagrelor monotherapy after 3-month DAPT was associated with lower primary outcome rate than ticagrelor-based 12-month DAPT regardless of HBR by ARC-HBR criteria, with similar magnitudes of therapy effect for HBR and non-HBR patients (p-interaction=0.400). Results were consistent by PRECISE-DAPT score (p-interaction=0.178). Conclusions: In ACS patients treated with DESs, ticagrelor monotherapy after 3-month DAPT was associated with lower rate of adverse clinical outcomes regardless of HBR, with similar magnitudes of therapy effect between HBR and non-HBR.

Left Atrial Appendage Occlusion in Non-Valvular Atrial Fibrillation in a Korean Multi-Center Registry

Kim, Jung-Sun,Lee, Hancheol,Suh, Yongsung,Pak, Hui-Nam,Hong, Geu-Ru,Shim, Chi Young,Yu, Cheol-Woong,Lee, Hyun-Jong,Kang, Woong-Chol,Shin, Eun-Seok UNKNOWN 2016 CIRCULATION JOURNAL Vol.80 No.5

<P>Background: The aim of this study was to evaluate clinical outcome after left atrial appendage (LAA) occlusion in real clinical practice and compare between Amplatzer cardiac plug (ACP) and Watchman. Methods and Results: From October 2010 to February 2015, 96 successful LAA occlusion procedures were performed using either ACP (n=50) or Watchman device (n=46) in non-valvular atrial fibrillation (AF) patients (59 male; age, 65.1 +/- 9.4 years; CHADS2, 2.5 +/- 1.2; CHA(2)DS(2)-VASC, 3.9 +/- 1.6; HAS-BLED, 2.7 +/- 1.3). The procedure success rate was 96.8%. There were serious complications in 4 patients (4.1%; 2 cardiac tamponade, 1 device embolization, and 1 major bleed). The anticoagulation cessation rate after 6 weeks was 92.7%. During mean 21.9-month follow-up, the incidence of death, stroke, systemic embolization and major bleeding was 5.2%, 4.2%, 0% and 1.0%, respectively. On transesophageal echocardiography of 93 patients within 6 months after the procedure, 24 residual leaks were observed (25.8%; 2 mild, 18 moderate, and 4 major). Clinical outcome was similar for the 2 devices, but peridevice leakage was more frequent with the Watchman than the ACP. Conclusions: LAA occlusion was feasible in non-valvular AF patients with high risk of stroke and hemorrhage. The ACP and Watchman devices were similar in terms of procedural and clinical outcomes.</P>

Impact of Angiotensin II Receptor Blockers on Clinical Outcomes after Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction Based on Data from the Korean National Health Insurance Database (2005–2014)

Gwang Sil Kim,Young-Guk Ko,Yongsung Suh,Hoyoun Won,Sung-Jin Hong,Chul-Min Ahn,Jung-Sun Kim,Byeong-Keuk Kim,Donghoon Choi,Myeong-Ki Hong,Yangsoo Jang 대한심장학회 2020 Korean Circulation Journal Vol.50 No.11

Background and Objectives: The effectiveness of angiotensin II receptor blockers (ARBs) compared with angiotensin converting enzyme inhibitors (ACEIs) in patients with acute myocardial infarction (AMI) has not been established. We investigated the effects of ARBs on clinical outcomes after percutaneous coronary intervention (PCI) in AMI patients. Methods: Patients receiving ACEIs or ARBs after AMI treated with PCI between January 2005 and December 2014 were selected from the Korean National Health Insurance Service database. The primary endpoint was major cardiovascular adverse event (MACE; all-cause death, myocardial infarct [MI], or stroke). Results: We included patients regularly taking ACEIs (n=22,331) or ARBs (n=28,533) (medication possession ratio ≥80%). Compared with the ACEI group, the ARB group contained more females (31% vs. 18%), were older (mean, 63 vs. 60 years), and had more comorbidities, including hypertension (62.8% vs. 44.8%), diabetes (33.9% vs. 26.4%), congestive heart failure (7.9% vs. 4.3%), chronic obstructive pulmonary disease (25.5% vs. 18.9%), and end-stage renal disease (1.3% vs. 0.4%) (p<0.001 for all). After propensity score–matching, ARBs were associated with a 23% lower risk of MACE (hazard ratio [HR], 0.774; 95% confidence interval [CI], 0.715–0.838; p<0.001) than ACEIs. ARB use was also associated with a significantly reduced risk of death (HR, 0.741; 95% CI, 0.659–0.834; p<0.001), MI (HR, 0.731; 95% CI, 0.638–0.837; p<0.001), and revascularization (HR, 0.816; 95% CI, 0.773–0.861; p<0.001). Conclusions: ARB use was associated with a lower risk of MACE, MI, and revascularization than ACEIs in our retrospective analysis of AMI patients who underwent PCI.

Outcomes of stents covering the deep femoral artery origin.

Hong, Sung-Jin,Ko, Young-Guk,Suh, Yongsung,Shin, Dong-Ho,Kim, Jung-Sun,Kim, Byeong-Keuk,Hong, Myeong-Ki,Jang, Yangsoo,Choi, Donghoon Société Europa édition 2014 EuroIntervention Vol.10 No.5

<P>To investigate the impact of coverage of the deep femoral artery (DFA) by stents during endovascular treatment of proximal superficial femoral artery (SFA) lesions involving its ostium on the patency of both femoral arteries.</P>

CIMT compared to Cardiac CT Ca score for estimating atherosclerosis in young fatty liver patient

( Incheol Yoon ),( Hyun-Jin Kim ),( Hyung-Bok Park ),( Yongsung Suh ),( Yoon-Hyeong Cho ),( Tae-Young Choi ),( Eui-Seok Hwang ),( Deok-Kyu Cho ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1

Background: As a surrogate of atherosclerosis, carotid intima-media thickness (IMT) and coronary artery calcium score (CACS) of over 100 by Cardiac CT scan can predict cardiovascular events. Fatty liver disease as a potential component of the metabolic syndrome is also linked to cardiovascular disease. This study evaluated the differences of the carotid IMT and the CACS in patients with fatty liver disease. Methods: The patients who had performed carotid, abdomen ultrasound and cardiac CT were evaluated retrospectively between Jun 2011 and December 2013. The primary outcome was the difference of the carotid IMT and the CACS between the fatty liver disease patients and patients with normal liver. Results: Among 819 patients (53.3 ±11.2 year), 330 patients had fatty liver disease. Patients with fatty liver disease had significant larger waist circumferences and body mass index. The incidences of hypertension, diabetes, and the dyslipidemia were also higher in patient with fatty liver disease. Furthermore, the carotid IMT was significantly thicker in patients with fatty liver disease than the patients with normal liver (0.79 ± 0.17 mm vs. 0.76 ±0.17 mm, p=0.012), and carotid plaque showed the more common tendency in patient with fatty liver disease (26.7% vs. 21.7%, p=0.099). The incidences of composite of the thick carotid IMT (≥75th percentile) and the plaque presence were significantly higher in fatty liver (43.0% vs. 36.0%, p=0.043). Especially patients under fifty years old, the carotid IMT was significantly thicker in patient with fatty liver than normal liver. Fatty liver disease increased the risk of the composite of the thick carotid IMT and the plaque in young patient (OR 1.83, 95% CI 1.00-3.34, p=0.05). However, the incidences of CACS of over 100 showed no significant difference between two groups. Conclusions: Carotid IMT reflect the worse baseline characteristics of the patients with fatty liver diseases than the CACS. Especially, fatty liver disease increase the risk of atherosclerosis in young patients under 50. Therefore, young patients with fatty liver disease need to perform screening IMT for detecting atherosclerosis and modifying the risk factors.

Clinical implication and consistency of inter-arm blood pressure difference in general population

( Hyunju Jeong ),( Hyun-jin Kim ),( Hyung-bok Park ),( Yongsung Suh ),( Tae-young Choi ),( Eui-seok Hwang ),( Deok-kyu Cho ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1

Background: There is limited data on clinical implication and consistency of serial measurement of increased inter-arm blood pressure difference (IIABPD) in general population. Methods: From May 2006 to April 2015, a total of 1650 patients (53 ±12 years old/71.2% males) have undergone serial pulse wave velocity and ankle brachial index (ABI) measurements (Median time interval: 12 months) with VP-1,000 (Omron) in Myongji health screening center. We evaluated the consistency of IIABPD over measurements and compared ABI and decrement of ABI according to IIABPD, which is defined as 10 mmHg or more of difference between systolic pressures of both arms. Results: The prevalence of IIABPD was 77 (4.7%) and 93 patients (5.7%) in index and followed measurement, respectively. There was significant correlation between index and followed IABPD (r=0.179, p <0.001). Although IIABPD of index measurement had significant correlation with IIABPD in follow-up (HR 5.53 [3.08-9.94 95%CI], p<0.001), the consistency rate of IIABPD was only 17 patients (22%) amongst 77 patients. When all of study population was divided into 4 groups according to increased IABPD as follows; No IIABPD, resolved IIABPD, newly developed IIABPD, consistent IIABPD group, ABI was significantly higher and the decrement of serial ABI was smaller in no or resolved IIABPD groups compared with newly developed or consistent IIABPD groups (Table 1). Conclusions: IIABPD of 10 mmHg or more was significantly associated with subclinical atherosclerosis. However, serial measurements revealed low consistency rate of IIABPD. These findings suggested the limitation of IIABPD as a simple marker for atherosclerosis.