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      • 經驗生命表의 作成을 위한 補整模型의 硏究

        권용만,장덕준,홍연웅 國立 昌原大學校 基礎科學硏究所 1993 基礎科學硏究所論文集 Vol.4 No.-

        This paper presents a general law of mortality that is equal to a mixture of Greville's nonparametric graduation model(difference order 3) and Gompertz parametric survival function. Using crude death rates for constructing Korea experience life table (male, 1991), we know that Greville's model including a samll number of weighted moving average terms graduates well up to age 10, but there is no significant difference above age 60. And we propose a revised King-Hardy method for estimating parameters of Gompertz, and show that the revised method performs well in terms of bias and mean square error. Finally, a numerical example is given.

      • Japonica 및 Indica ×Japonica 品種의 細胞核 DNA의 特性 硏究

        權容雄,蘇昌鎬 서울大學校 農科大學 1985 서울대농학연구지 Vol.10 No.2

        벼의 品種群間 染色質 및 核 DNA의 특성을 비교하기 위하여 Japonica 品種인 삼남, 설악과 Indcia×Japonica 品種인 삼강, 풍산을 파종하여 5葉期에 뿌리를 사용하여 실험한 결과를 요약하면 다음과 같다. 1. 核當 DNA 함량은 설악 2.16×10??g, 삼남 2.07×10??g, 삼강 2.21×10??g, 풍산 2.42×10??g으로 Japonica보다 Indica×Japonica가 약간 많은 경향이었다. 2. 핵당 RNA, 核단백질中 염산에 용출된 단백질(大部分 histones) 및 기타 단백질의 DNA에 대한 함량비는 각각 0.14∼0.18, 0.87∼1.02, 2.99∼3.54로 품종간 차이는 있었으나 一樣性을 보이지 않았다. 3. DNA의 denaturation 온도 특성(Tm)은 설악 70.5℃, 삼남 71.0℃, 삼강 71.5℃, 풍산 69.5℃이었고, GC함량은 설악 40.5%, 삼남 41.7%, 삼강 42.9%, 풍산 38.6%으로 일정한 경향은 없었다. 4. DNA의 renaturatron (50℃)은 설악 62.8%, 삼남 66.3%, 삼강 54.0% 및 풍산 54.3%으로 Japonica 품종이 Indica×Japonica 품종보다 renaturation이 잘 되었다. Some biochemical characteristics of chromatin and nuclear DNA isolated from rice roots were compared for Japonica varieties, Samnam and Seolak, and Indica×Japonica varieties, Samgang and Pungsan. Hydroponically grown rice roots were harvested at the 5th leaf stage. The roots were washed three times or more with distilled water and then the nuclei and the chromatins were isolated and purified. The results are summarized as follows: 1. DNA content per nucleus was 2.16×?? in Seolak, 2.07×?? in Samnam, 2.21×?? in Samgang, and 2.42×?? in Pungsan. The DNA content per nucleus was smaller in the Japonicas than in the Indica×Japonicas. 2. Content ratio of RNA to DNA was 0.14 to 0.18, HCl-soluble proteins (mostly histones) to DNAwas, 0.87 to 1.02, and NACl- and Chloroform/MeOH soluble proteins (non-histones)to DNAwas, 2.99 to 3.54. 3. Transition temperature of DNA occurred at 70.5℃ in Seolak, at 71.0℃ in Samnam, at 71.5℃ in Samgang, and at 69.5℃ in Pungsan. GC content ratio was 40.5% in Seolak, 41.7% in Samnam, 42.9% in Samgang, and 38.6% in Pungsan. 4. Renaturation percent was 62.6% in Seolak, and 66.3% in Samnam, and 54.0% in Samgang, and 54.3% in Pungsan when heated DNA at 95℃ for 5 minutes was slowly cooled to 50℃, Japonica varieties being renatured to a greater degree than Indica×Japonicas.

      • KCI등재후보

        선삭가공에서 절삭력을 이용한 공구마멸의 감지

        윤재웅,이권용,이수철,최종근 한국공작기계학회 2001 한국생산제조학회지 Vol.10 No.1

        The development of flexible automation in the manufacturing industry is concerned with production activities performed by unmanned machining system. A major topic relevant to metal-cutting operations is monitoring tool wear, which affects process efficiency and product quality, and implementing automatic tool replacements. In this paper, the measurement of the cutting force components has been found to provide a method for an in-process detection of tool wear. The static components of cutting force have been used to detect flank wear. To eliminate the influence of variations in cutting conditions, tools, and workpiece material, the force modeling is performed for various cutting conditions. The normalized force disparities are defined in this paper, and the relationships between normalized disparity and flank wear are established. Finally, artificial neural network is used to learn these relationships and detect tool wear. According to the proposed method, the static force components could provide the effective means to detect flank wear for varying cutting conditions in taming operation.

      • 도심지 가로경관의 시지각적 이미지 특성에 관한 연구

        김용권,박성진,이청웅 朝鮮大學校 建設技術硏究所 2004 建設技術硏究 Vol.24 No.2

        This research is a stage of psychological experiments to analyze the image valuation system with Gwang-Ju Sang-rnu new city development site as the subject, to compare the subject streetscape as in a psychological experiment, to examine what points of view the image users take and select categories for a questionnaire. Therefore, a repertoire grid-development system was used to psychologically experiment and clarify the images of high-rise residential section streetscape, and the result is as following. Group1 is a typical high-rise residential section, which form and color of the buildings appears to have a simple, clean, and natural image. Group2 is consisted of multiple-story commercial buildings with signboards, and had a negative image. In contrast, multiple-story commercial buildings and high-rise residential buildings had a bright, clean, stabile image. Group3 is the most affirmatively preferred tendency which abundant continuative greenery on high-rise residential and business sections is emphasized by the bright, light colored roadside buildings that brought generally increased preference. Group4 is a group which is a business section with connective commercial buildings and construction sites mixed has the lowest preference tendency, and also has a negative tendency of lower than 4.0 of the 14 image categories.

      • 기본 항암 화학요법에 불응 하는 전이성 이행상피 세포암 환자에서 시행한 증량 M-VAC 항암 화학 요법 2례

        조용현,권병산,이지열,김세웅,이충범,윤문수 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.3

        1. 목적 전이성 방광 이행 상피 세포암의 경우에 시행될 수 있는 몇가지 전신적 항암 요법 중 M-VAC 병용 투여가 가장 인정받고 있는 항암 요법이긴 하나 일시적 반응 후 재발시 즉 M-VAC 병용투여에 불응하는 경우 증상 완화 요법(palliative therapy) 이외에 다른 치료 방법이 없었다. 저자들은 M-VAC 병용 요법에 불응하는 전이성 방광 이행상피 세포암 환자 2례에서 기존 M-VAC 항암 화학 요법보다 항암제 투여량을 증량한 M-VAC 항암 요법을 시행하였다. 2. 방법 기존 M-VAC 항암 화학요법용량(Methotrexate 30㎎/㎡, Vinblastine 3㎎/㎡, Adriamysin 30㎎/㎡, Cisplatin 70㎎/㎡)보다 항암제 용량을 증량하고(Methotrexate 30㎎/㎡, Vinblastine 4㎎/㎡, Adriamycin 60㎎/㎡, Cisplatin 100㎎/㎡) 이로 인한 골수 저하증을 예방하기 위하여 GM-CSF를 동시에 투여하였다. 3. 결과 증례 1 환자는 중량 항암 화학 요법 1개월 후 추적검사에서 전이된 임파절이 모두 소실된 완전 관해를 보였으며 증례 2 환자는 증량 항암 요법 후 14일째 폐혈증으로 사망하였다. 4. 결론 증량 M-VAC 항암 화학 요법은 아직 시행 기간 및 증례가 많지 않아 완전 관해 기간 및 적절한 항암요법 시행 횟수의 미확립, 항암제 치료 도중의 치사율의 감소등이 문제점으로 지적되고 있으나 기존 M-VAC 항암 요법에 불응하는 전이성 방광이행 상피 세포암 환자에서 우선 고려될 수 있는 치료법으로 사료된다. Background : M-VAC(methotrexate, vinblastine. doxorclbicin, cisplatin) chemotherapy is the most common and effective treatment modality for advanced transitional bladder tumor. However, there is no effective therapy in case of the patients nith bladder tumor refractory to M-VAC chemotherapy. Methods : Two male patients mith metastatic transitional bladder tumors refractory to conventional chemotherapy with methbtrexate, vinblastine, doxorubicim, and cispiatin (M-VAC) were treated with escalate3 dose of M-VAC plus recombinant human granulocyte-macrophage colony stimulating factor (rhGM-CSF). Formula of escalated M-VAC chemotherapy were 30mg/m^(2) of inethotrexate, 4mg/m^(2) of vinblastine. 60rmg/m^(2) of doxorubicm, and 10Omg/m^(2) of cisplatin, and 250mg/m^(2) rhGM-CSF per day administered subcutaneously (SC) for 10 consecutive days. Result : One of the treated patients mas responded with complete remission and the other one m-as dead by sepsis on post-escalated M-VAC chenctherapy 14 days. Coclusion : We believe escalated M-VAC chemotherapy may be one of the effective alternative treatment for patients with metastatic urothelial tumor refractory to conventional M-VAC chemotherapy.

      • 사이버 여행기업 이용자의 만족도 분석

        이응규,김용완,권현재 한국관광정보학회 2003 觀光情報硏究 Vol.- No.13

        This is an empirical study on the user's satisfaction to cyber travel agencies. The digital trend has pur our travel market into a transition period. The number of internet sites related with domestic travel have been growing day by day. But they don't provide the consumers with enough information of the products they offer. They are nothing better than a home page introducing themselves. This study is designed to establish the theoretical backgrounds of the cyber travel agencies and their present situations inn Korea through satisfaction analysis in order to find out solutions to the problems they face, eventually developing the models for the internet business. This study analyses recent cyber travel market all of the world and suggests strategies for cyber travel agencies. Main suggestions to be successful cyber travel agencies are as follows; Cyber travel agencies have to (1) respond to changing environment on internet industry and user's needs; (2) develop new travel products and websites to appeal special interset segments; (3) cooperate with business partner to elevate competitiveness in cyber travel market.

      • 作期移動에 따른 水稻 F₂世代의 登熟特性 分離樣相의 變化

        申辰澈,權容雄 서울大學校 農科大學 1985 서울대농학연구지 Vol.10 No.2

        水稻의 品種育成上 Indica×Japonica 交雜種에 있어서 多數性 및 收量 安全性 向上을 위해 必要한 登熟期間 중 葉身의 老化와 登熟과의 關係를 밝히고자, 早生統一, 水原 264號, T(N)1을 母木으로 하는 3組合의 F₂集團을 適期栽培와 晩期栽培였고, 各 栽培時期別 組合當 1000個體씩을 供試하여 出穗以後 登熟期間中의 葉綠素含量, 葉面積, 粒重發特性 關係形質을 調査하였다. 1. 出穗期 葉綠素含量은 全般的으로 適期栽培보다 晩期栽培에서 낮았으며, 適期에서는 組合間 平均差異가 없고 變異係數는 早生統一/T(N)1, 水原 264/T(N)1 및 早生統一/水原 264가 各各 15.4, 15.3, 17.4%이었고, 晩期栽培에서는 變異係數가 24.1, 16.4, 19.6%이었으며, 晩期栽培에서는 葉綠素含量이 높은 個體數가 적었다. 出穗後 30日의 葉綠素含量은 適期에서 早生統一/T(N)1, 水原 264/T(N)1, 早生統一/水原 264의 平均이 3.03, 2.71, 2.96㎎/g dry wt.이었고, 變異係數가 28.5 34.6 33.5%이였으며, 晩期栽培에서는 平均이 2.23, 2.30, 2.48㎎/g dry wt. 變異係數가 39.2, 32.7, 28.3%이었다. 2. 出穗期의 葉面積은 適期와 晩期의 分布 差異가 없었고, 組合間에 差異가 없었다. 出穗後 30日의 葉面積은 變異係數가 早生統一/T(N)1, 水原 264//T(N)1 및 早生統一/水原 264의 各組合에서 適期는 27.1, 18.4, 21.8%이었고 晩期에서는 21.0, 18.4, 22.4%이었고, 組合間에는 平均間差가 컸다. 3. 出穗後 30日동안 減少된 葉綠少量에 對한 變異係數는 適期栽培에서 早生統一/T(N)1, 水原 264/T(N)1 및 早生統一/水原 264의 各 組合은 28.3, 27.0, 31.7이였고, 晩期栽培에서는 各各 39.9, 35.0, 28.4이었다. 4. 適期栽培에서는 모든 組合이 出穗後 20日, 30日 및 最終粒重의 分布樣相이 비슷하였으나, 晩期栽培에서는 各各 다른 分布樣相을 보였다. 5. 出穗期間은 適期栽培에서 모든 組合들이 25日 程度였고, 早生統一/T(N)1 組合의 平均 出穗日은 다른 두 組合보다 平均 出穗日이 7日程度 빨랐으나, 晩期栽培에서는 그 差異가 적어졌다. 6. 出穗가 늦어진 個體는 葉綠素含量이 낮아지는 傾向이었으나, 出穗가 늦은 個體들 中에서 葉綠素含量이 높은 個體도 많았다. 出穗期의 葉面積은 出穗期와 正의 相關이었는데, 出穗後 30日의 葉面積과 出穗時期와는 適期에서 負의 相關이었고, 晩期에서는 正의 相關이었다. 晩期栽培에서는 出穗가 늦어짐에 따라 葉綠素含量의 減少는 적었고, 葉面積의 減少는 出穗期와 正의 相關關係였다. 7. 出穗期 葉面積과 出穗기 葉綠素含量과는 相關關係가 없었고, 出穗後 30日의 葉綠素含量과 出穗後 30日의 葉面積과는 正의 相關關係였다. 8. 出穗期 葉綠素含量과 出穗期 20日, 30日 및 最終粒重과는 正의 相關關係이었고, 出穗後 30日의 葉綠素含量과 適期栽培의 出穗後 20日, 30日의 粒重과도 正의 相關關係였다. 9. 出穗期의 葉面積과 粒重과는 相關關係가 없었다. 出穗後 30日의 葉面積은 出穗後 30日 및 最終粒重과 正의 相關關係였다. 10. 晩期栽培에서 葉綠素 減少量과 出穗後 30日 및 最終粒重과는 正의 相關關係이었다. 適期 및 晩期栽培에서 모두 葉面積 減少率 및 葉身 老化指數는 出穗後 30日 및 最終粒重과는 負의 相關이었다. 11. 出穗後 20日의 粒重과 乾物蓄積速度와는 가장 높은 相關關係였고, 出穗後 20日의 乾物蓄積程度와 出穗後 30日의 乾物蓄積程度도 正의 相關이 있었다. 그러나 最終粒重과 乾物蓄積程度와는 相關이 없었다. 12. 出穗後 20日에 最終粒重에 하는 個體數는 組合에 따라 다르고 出穗後 20日에 이미 最終粒重에 달하는 個體가 30% 程度되는 組合도 있었다. The segregation mode in the late season culture (June 15 transplanting) of chlorophyll content of leaves, and alive leaf area during grain filling period and filling of grains in F₂ progenies of the rice varieties was compared to that in the ordinary season culture (June 5 transplanting) to improve selection method of the cold susceptible IndicaxJaponica rice progenies for better grain filling under cooler climate of ripening. IndicaxJaponica varieties, Josaengtongil and Suwon 264 were crossed each other and with Taichung Native 1; Josaengtongil/T(N) 1, Suwon 264/T(N), and Josaengtongil/Suwon 264. Twentyfour, 10, and 20 F₁ plants from each of the above crosses, Respectively, were grown and harvested in bulk. The 1,000 F₂ individuals per combination were cultured and observed in the field for each seasonal culture. The results obtained are summarized as follows: 1. At heading, the chlorophyll content was lower in the late season culture than in the ordinary. Differences among the means of chlorophyll content in F₂progenies were not significant in the ordinary season culture, and there were fewer individuals with high chlorophyll content in the late season culture than in the ordinary. The coefficients of variance (C.V.) obtained from the distribution of chlorophyll content at heading in the F₂progenies of Josaengtongil/T(N) 1, Suwon 264/T(N) 1 and Josaengtongil/Suwon 264 were estimated to be 15.4, 15.3, and 17.4% in the ordinary season culture, and 24.1, 26.4 and 19.6% in the late season culture, respectively. At 30 days after heading, each combination averaged 3.03, 2.71, 2.96mg/g. D.M. in the late season culture. The coefficients of variance obtained from the distribution of chlorophyll content at 30 days after heading in each cross were 28.5, 34.6, 33.5% in the ordinary season culture and 39.2, 32.7, 28.3% in the late season culture. 2. At heading, there observed the similar distribution of leaf area in the F₂progenies in both of the ordinary and the late season culture, and no significant differences among means of the leaf area in the F₂progenies. At 30 days after heading, the C.V.s in the three F₂progeny groups were 27.3, 18.4, 21.8% in the ordinary season culture and 21.0, 18.4, 22.4% in the late season culture, showing great differences among means of leaf area in the progenies. 3. For the C.V.s obtained from the distribution of the decreased amount of chlorophyll during 30 days after heading, the three F₂progeny groups, Josaengtongil/T(N) 1, Suwon 264/T(N) 1 and Josaengtongil/Suwon 264, showed 28.3, 27.0, 31.7% in the ordinary season culture and 39.9, 35.0, 28.4% in the late season culture, respectively. 4. In all F₂progenies grain weight at 20 and 30 days after heading and at maturity were similar in mode of segregation in the ordinary season culture, but different in the late season culture. 5. Duration from initial to final heading was about 25 days in all crosses in the ordinary season culture, and average growth duration to head was shorter in the Josaengtongil/T(N) 1 than the other crosses by 7 days in the ordinary season culture, but no difference was observed among the F₂progenies in the late season culture. 6. The chlorophyll content of the individuals tended to decrease with heading date delay, but even among the individuals of late heading, many of them also showed high chlorophyll content. In both cultivated seasons, the leaf area at heading increased significantly with the growth duration to head while the leaf area at 30 days after heading was negatively correlated with the growth duration to head in the ordinary season culture, but positively. in the late seasonculture The decrease in chlorophyll content got smaller with the heading date in the late season culture, and the decrease in leaf area was positively correlated with the heading date. 7. The leaf area at heading showed no significant correlation with the chlorophyll content at heading, while the leaf area at 30 days after heading was positivelycor related to the chlorophyll content at 30 days after heading. 8. In both cultivated seasons, the chlorophyll content at heading was positively correlated with the grain weight at 20 and 30 days after heading, and that at 30 days after heading showed positive relationship with the grain weight at 20 and 30 days after heading only in the ordinary season culture. 9. There was no significant relationship between the leaf area at heading and grain weight, but the leaf area at 30 days after heading was positively correlated with the grain weight at 30 days after heading and at harvest. 10. In the late season culture, the decreased amount of chlorophyll during 30 days after heading showed a positive correlation with the grain weight at 30 days after heading and at harvest. The decrease in leaf area during 30 days after heading and the leaf senescence index were negatively correlated with the grain weight at 30 days after heading and at harvest in both cultivated seasons, each other. 11. There was the highest positive correlation between grain weight and the grain filling rate at 20 days after heading and there was highly positive correlation between the grain weight at 20 days and that at 30 days after heading. But there was no significant correlation between the grain weight at 20 days and 30 days after heading and grain weight at harvest. 12. The number of F₂progenies, which reached the physiological maturity at 20 days after heading, varied with crosses, and in the cross of Josaengtongil/Suwon 264, the fully ripened F₂progenies at 20 days after heading amounted to about 30%.

      • 水稻 遠緣品種들의 葉綠體 色素系 組成 및 그와 花靑素含量의 登熟期間中 變化

        金柱憲,權容雄 서울大學校 農科大學 1977 서울대농학연구지 Vol.2 No.2

        The chloroplast pigment composition, its change and anthocyanins development during grain ripening were studied in relation to the reddish discoloration and earlier leaf senescence prominent in the Indica × Japonica cross varieties, using Jinheung, a Japonica, T(N)-1, an Indica, IR1317 and Suwon No. 256, Indica × Japonica progenies. 1. Chloroplast pigments of rice leaf blade were composed of β-carotene (Rf 0.898), pheophytin a (Rf 0.616), lutein (Rf 0.477), chlorophyll a′(Rf 0.398), chlorophyll a (Rf 0.323), chlorophyll b′(Rf 0.247), chlorophyll b (Rf 0.198), violaxanthin (Rf 0.101), neoxanthin (Rf 0.037) as separated on thin layer of silica gel with 5% binder, employing solvent system developed in this experiment of petroleum ether: acetone=4:1(v/v) and identified on the basis of their absorption spectra after elution. 2. All of the pigments were present in all varieties tested throughout the course of leaf senscence after heading. But, there was distinct varietal difference in the relative content of the pigments: the greatest variation among varieties existed in the content of neoxanthin (C.V.=57%) and the least in the content of chlorophyll b (C.V.=5%). 3. The total content of carotenoid pigments relative to that of chlorophyll a decreased in the variety T(N)-1 and Suwon No. 256 during 20 days after heading, while it increased in the variety Jinheung and IR1317-266-34 during the same period. The increase shown in the variety Jinheung was mainly due to increase in the relative content of β-carotene and lutein, and in the variety IR1317-266-34 it was due to β-carotene, violaxanthin and neoxanthin. 4. Fast decrease in the chlorophyll content occurred during the first 10 days after heading in the variety T(N)-1 and IR1317-266-34 in contrast to later and gradual decrease in the variety Jinheung and Suwon No. 256. 5. Total anthocyanins content of the leaf blade began to increase at about 5 days after heading in the variety Suwon No. 256 and at about 20 days in the variety Jinheung, IR1317-266-34 and T(N)-1. The fastest accumulation occurred at 20-25 days after heading in the variety Jinheung and IR1317-266-34, 25-30 days in the variety T(N)-1, 30-35 days in the variety Suwon No. 256. With respect to variety the order of magnitude in the maximum content shown after heading was T(N)-1<Suwon No. 256<Jinheung<IR1317-266-34. 6. Highly significant negative correlationship was found between the contents of chlorophyll and total anthocyanins during the course of leaf senescence in the variety Jinheung (??), IR1317-266-34 (??) and T(N)-1 (??), but such a correlation was not observed in the variety Suwon No. 256 (??).

      • 水稻 遠緣品種들의 登熟期間中 葉身老化, 米粒發達및 그 品種間 差異

        金柱憲,權容雄 서울大學校 農科大學 1977 서울대농학연구지 Vol.2 No.2

        To elucidate the characteristics of leaf senescence in relation to the development of rice grain, course of change in the content of chlorophylls, soluble protein, and total phenolics, course of increase in dry weight of rice caryopsis, and their interrelationships were studied, using Jinheung, a typical Japonica variety, T(N)-1, an Indica, IR 1317-266-34 and Suwon No. 256, Indica×Japonica progenies. The results obtained are summarized as follows: 1. The variety T(N)-1 and IR 1317-266-34 showed a sigmoidal time course of the rice caryopsis development in dry weight in contrast to the continuous increase in the dry weight of rice caryopsis to 40 days after heading in the variety Jinheung and Suwon No. 256. 2. The chlorophyll content of leaf blades decreased during the course of grain development; the degree of decrease in the chlorophyll content being the highest in the IR 1317-266-34 and being the lowest in the Suwon No. 256. 3. Total pheonolics content of the leaf blades increased during the course of grain development, showing varietal difference in the accumulation pattern: major accumulation occurred during 30 to 35 days after heading in the Jinheung and IR 1317-266-34 in contrast to a rather linear increase after heading in the Suwon No. 256 and T(N)-1. 4. The content of soluble protein of the leaf blades decreased during the course of grain development in all varieties tested except for the Suwon No. 256, which showed some increase in the flag leaf during the first 15 days after heading and little decrease in other leaves during the later period. 5. Significant positive correlationship existed between the chlorophyll content and the soluble protein content of leaf blades during their senescence, r value being ??, ??, ??, ??, respectively for the Jinheuing, T(N)-1, Suwon No. 256, and IR 1317-266-34.

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