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Jung, Yong-Taek,Bae, Jin-Woo,Jeon, Che Ok,Joh, Kiseong,Seong, Chi Nam,Jahng, Kwang Yeop,Cho, Jang-Cheon,Cha, Chang-Jun,Im, Wan-Taek,Kim, Seung Bum,Yoon, Jung-Hoon The National Institute of Biological Resources 2016 Journal of species research Vol.5 No.1
During recent screening to discover indigenous prokaryotic species in South Korea, a total of 31 bacterial strains assigned to the class Gammaproteobacteria were isolated from a variety of environmental samples including soil, tidal flat, freshwater, seawater, and plant roots. From the high 16S rRNA gene sequence similarity (>98.7%) and formation of a robust phylogenetic clade with the closest species, it was determined that each strain belonged to each independent and predefined bacterial species. There is no official report that these 31 species have been described in South Korea; therefore 5 species of 3 genera in the order Alteromonadales, 11 species of 3 genera in the order Pseudomonadales, 8 species of 6 genera in the order Enterobacteriales, 2 species of 1 genera in the order Vibrionales, 1 species of 1 genera in the order Oceanospirillales, 3 species of 3 genera in the order Xanthomonadales, and 1 species in the order Spongiibacter_o within the Gammaproteobacteia are reported for proteobacterial species found in South Korea. Gram reaction, colony and cell morphology, basic biochemical characteristics, isolation source, and strain IDs are also described in the species description section.
Yong Koo Kang,Jong Chan Im,Jae Pil Shin,In Taek Kim,Dong Ho Park 대한안과학회 2017 Korean Journal of Ophthalmology Vol.31 No.5
Purpose: To evaluate the change of residual volume of eye drop after instillation in patients with 23-gauge microincision vitrectomy surgery (MIVS). Methods: Patient who were treated 23-gauge MIVS from November 2014 to July 2015 were included. The residual volume was defined as the amount of remnant eye drop in patient’s eyes after instillation, calculated as the difference between instillation volume and spilled volume of eye drop. Calculation of residual volume of eye drop was performed one day before surgery, and daily from postoperative day 1 to day 5. Results: Forty consecutive patients were included. The residual volume of eye drop decreased from 30.3 ± 1.4 μL at baseline to 13.0 ± 1.5 μL at day 1, 18.3 ± 1.6 μL at day 2, 24.7 ± 1.5 μL at day 3, and 27.9 ± 1.4 μL in day 4, postoperatively (p < 0.001, respectively). The volume at postoperative day 5 was 29.4 ± 1.3 μL, but it was not different from the volume at baseline (p = 0.105). The change of residual volume was significantly correlated with postoperative chemosis (r = 0.672, p < 0.001) and effected by the number of quadrant with postoperative chemosis (p < 0.05). Conclusions: This study shows that postoperative residual volume of eye drop after instillation decreased until postoperative day 4, and postoperative chemosis affects the change of residual volume. Thus, checking proper use of eye drops and teaching about instillation technique by physician is necessary for patients with 23-gauge MIVS.
( Yong Il Kim ),( Roshan Pradhan ),( Bijay K Paudel ),( Ju Yeon Choi ),( Ho Taek Im ),( Jong Oh Kim ) 영남대학교 약품개발연구소 2016 영남대학교 약품개발연구소 연구업적집 Vol.26 No.-
In this study, the enteric-coated delayed-release pellets of duloxetine hydrochloride (DLX) were formulated using a fluidized bed coater. Three separate layers, the drug layer, the barrier layer, and the enteric layer, were coated onto inert core pellets. Among the three formulations (FI-F3), the dissolution profiles of formulation F2 were most similar to those of the marketed product, with similarity and difference factors of 83.99 and 3.77, respectively. In addition, pharmacokinetic parameters of AUC, C<sub>max</sub>, T<sub>max</sub>, t<sub>1/2</sub>, K<sub>e1</sub> and MRT of DLX for the developed formulation (F2) did not differ significantly from those for the marketed product in beagle dogs, suggesting that they were bioe-quivalent. Our results demonstrated that the in vitro dis-solution data resembled the in vivo performance of the drug. Therefore, this study has a positive scope for further scale up and development of the formulation for achieve-ment of the generic product.
알파인 스키어의 부위별 상해 원인 및 유형과 처치에 관한 문헌 고찰
임용택,윤영선,김난수 고려대학교 스포츠과학연구소 1997 스포츠科學論叢 Vol.9 No.1
The purpose of this study is to prevent of the injury with careful consideration about string that is the most popular sports among the various winter one. Because the needs for leisure is increasing rapidly in everyday life. Moreover we try to fix the string as a leisure spots through the appropriate precautionary. In review papers and all kinds of statistical data, the most of injury from ski are sprain, dislocation, fracture and especially a wound to the knee. Recently, although the frequency of the injury has decreased by scientific ski set but we must pay close attention to that because it can bring fatal outcome. The most of the injury are caused by carefulness, defect of the equipment, and unskilled string. As a prevention for those we have to understand and learn correctly how to string and put on fit the equipment. So, they need the preparatory learning by systematic organs of education such as ski school before string and we must bring up the proper skier by opening many courses.
Im, Sang-Taek,Jo, Youn Yi,Han, Gayoung,Jo, Hyun Jung,Kim, Yong Ho,Park, Chul-Kyu Hindawi 2018 Mediators of inflammation Vol.2018 No.-
<P>Dexmedetomidine, an <I>α</I>2-adrenoceptor agonist, is widely used as a sedative and analgesic agent in a number of clinical applications. However, little is known about the mechanism by which it exerts its analgesic effects on the trigeminal system. Two types of voltage-gated sodium channels, Na<SUB>v</SUB>1.7 and Na<SUB>v</SUB>1.8, as well as <I>α</I>2-adrenoceptors are expressed in primary sensory neurons of the trigeminal ganglion (TG). Using whole-cell patch-clamp recordings, we investigated the effects of dexmedetomidine on voltage-gated sodium channel currents (<I>I</I><SUB>Na</SUB>) via <I>α</I>2-adrenoceptors in dissociated, small-sized TG neurons. Dexmedetomidine caused a concentration-dependent inhibition of <I>I</I><SUB>Na</SUB> in small-sized TG neurons. <I>I</I><SUB>Na</SUB> inhibition by dexmedetomidine was blocked by yohimbine, a competitive <I>α</I>2-adrenoceptor antagonist. Dexmedetomidine-induced inhibition of <I>I</I><SUB>Na</SUB> was mediated by G protein-coupled receptors (GPCRs) as this effect was blocked by intracellular perfusion with the G protein inhibitor GDP<I>β</I>-S. Our results suggest that the <I>I</I><SUB>Na</SUB> inhibition in small-sized TG neurons, mediated by the activation of Gi/o protein-coupled <I>α</I>2-adrenoceptors, might contribute to the analgesic effects of dexmedetomidine in the trigeminal system. Therefore, these new findings highlight a potential novel target for analgesic drugs in the orofacial region.</P>
Klinefelter 증후군에 병발된 원발성 종격동 생식세포종
김용조 ( Yong Jo Kim ),권교선 ( Gyo Seon Kwun ),이영우 ( Young Wo Lee ),김경태 ( Kyung Tae Kim ),박연희 ( Yeon Hee Park ),류백렬 ( Baek Yeol Ryoo ),김태유 ( Tae You Kim ),임영혁 ( Young Hyuck Im ),이춘택 ( Choon Taek Lee ),강윤구 대한결핵 및 호흡기학회 1996 Tuberculosis and Respiratory Diseases Vol.43 No.6