우심방을 침범한 거대 비호지킨씨 림프종 1예

강상범,진승원,이은경,박용현,최용호,김용주,박준철,김재형,홍순조,최규보,권종범,원용순,박건,이은희 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

2007년 대한감염학회 권장 성인 예방접종 권장안

강진한,김홍빈,손장욱,이상오,정문현,정희진,최영화,최정현,최준용,최희정 대한감염학회 2008 감염과 화학요법 Vol.40 No.1

In 2007, the Korean Society of Infectious Diseases recommended an immunization schedule for adults residing in Korea. This recommendation includes four categories: standard immunization for healthy persons, supplementary immunization for persons with underlying illnesses, recommendations for health-care personnel and for international travelers. The Standard Immunization Schedule consists of universal vaccination (tetanus-diphtheria/tetanus-diphtheria-pertussis (Td/Tdap); hepatitis A vaccine for persons aged 20s; human papilloma virus vaccine for women under 26 years old; meningococcal vaccine for military recruits and college students in dormitories; influenza vaccination for persons aged 50 years or more and pregnant women; and pneumococcal vaccination for persons aged 65 years or more) and catch-up vaccination (hepatitis A vaccine for persons aged 30s; hepatitis B vaccine, varicella and MMR vaccines for persons who have uncertain specific immunities). The Supplementary Immunization Schedule recommends 4 vaccines, i.e., pneumococcal, influenza, meningococcal, and Haemophilus influenzae type b, appropriate to the underlying illnesses, and confirmation of the presence of antibodies to hepatitis A and hepatitis B. The Recommendation for Health-Care Personnel includes universal vaccination (influenza and pertussis) and catch-up vaccination (hepatitis B, measles-mumps-rubella and varicella for seronegative health-care personnel). The Recommended Immunization for International Travelers focuses reinforcement of vaccinations for healthy persons and includes certain immunizations necessary for international travel (yellow fever, meningococcal, plaque, tick-borne encephalitis, and cholera). These guidelines can be seen at www.ksid.or.kr.

고령토로부터 알루미나 추출에 관한 연구(Ⅲ):염산에 의한 추출

최세영,이용근,이희수,김형국 연세대학교 산업기술연구소 1992 논문집 Vol.24 No.1

The preparation conditions of alumina powder extracted by hydrochloric acid from domestic San-Cheong kaolin have been investigated. In order to obtain best conditions to extract alumina by hydrochloric acid, experiments carried out with various acid concentrations, reaction temperatures, reaction times, and pH. The optimum conditions were 20 wt.-% for hydrochloric aicd concentration, 100℃ for reaction temperature, 7hrs for reaction time and pH8. The yield of alumina found to be 89.2wt.-% under these conditions. Two drying methods, direct and ethanol distillation drying method to control the precipitated agglomeration have deen compared. The ethanol distillation drying method revealed more narrow particle size distribution and less agglomerate than the direct drying method.

스위치드 릴럭턴스 전동기의 토오크 리플 저감을 위한 폴 형상 최적화

최용권,윤희성,황인성,고창섭 충북대학교 컴퓨터정보통신 연구소 2006 컴퓨터정보통신연구 Vol.14 No.1

최근 스위치드 릴럭턴스 전동기(Switched Reluctance Motor)는 고효율, 안정성, 용이한 가변 속도, 그리고 유지 보수의 불필요성 등의 장점으로 인하여 산업의 많은 분야에서 사용이 증대되고 있다. 그러나 SRM은 고정자와 회전자가 모두 돌극(Saliency) 구조를 이루며 펄스 형태의 여자 방식으로 구동되기 때문에 소음과 진동의 원인이 되는 토오크 리플이 크다는 단점을 갖는다. 토오크 리플 저감을 위한 기존의 연구는 주로 턴온 각 (θ_(on))과 턴오프 각 (θ_(off))조정, 고정자 극호(β_(s)) 그리고 회전자 극호 (β_(r))를 조정하는데 초점을 두었다. 그러나 고속 구동 시에는 여자 전류의 확립을 위한 충분한 시간이 필요하므로 스위칭 각도를 조정하여 토오크 리플을 저감하는 방법에는 한계가 있다. 따라서 본 논문은 턴온 각, 턴오프 각, 고정자 극호, 그리고 회전자 극호가 고정되어 있는 경우 고정자 돌극의 형상 변화를 통한 토오크 리플 저감법을 제안하고 반응표면법(Response Surface Methodology)을 이용하여 최적화를 수행하였다. Recently the switched reluctance motor(SRM) is highly expected to have more and more growing applications because it has many advantages over the other type motors such as high torque/weight ratio, robustness, easy variable speed and less maintenance. However, the SRM has large torque ripple which is caused by the excitation method of the pulse waveform and the saliency of both the stator and the rotor. The prior researches on the reduction of torque ripple are mainly focused on optimizing the switching angle, stator pole arcs, and rotor pole arcs. In high speed operation, however, it has a limitation to control the switching angle for the reduction of torque ripple because enough time is required in the establishment of exciting current. This paper shows that the torque ripple can be successfully minimized by optimizing the shape of the stator pole without controlling the switching time, stator pole arcs and rotor pole arcs.

열간단조 후 공냉에 의해 제조된 내마모강의 마모특성

최병영,김익수,장병록,이용희 대한금속재료학회 2003 대한금속·재료학회지 Vol.41 No.4

Wear of blades, buckets, plates and chisel occurred in operation of construction machinery, agricultural equipments, earthmoving equipments and offshore structures cause earlier failure of the components, resulting in the increased energy consumption, cost of maintenance and replacement. To solve the problems, advanced materials with higher resistance to abrasive wear have been attempted to make through alloy design and hot deformation followed by air cooling. 0.25C-1.4Mn-1.0Cr-0.7Ni-0.2Mo-0.08V-0.02Cu steels produced by hot forging were cooled in air to form bainite, showing higher resistance to wear than any other steels with different chemical composition in the sliding wear tests under the applied load of 74N. Higher strain hardening during sliding wear of 0.25C-1.4Mn-1.0Cr-0.7Ni-0.2Mo-0.08V-0.02Cu steels to cause microploughing wear mode seems to be one of the main reasons for showing higher resistance to wear than any other steels in this study.

아세클로페낙 연질캡슬(클란자 에스 연질캡슬)의 개발

용철순,이경희,최진석,박병주,정세현,김용일,박상만,배명수,김귀자,김영식,유창훈,강성룡,유봉규,이종달,최한곤 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.1

To develop and aceclofenac soft capsule, four preparations with various solubilizers were prepared and their dissolution test was carried out. Among four preparations tested, a preparation with ethanolamine was selected a formula of aceclofenac soft capsule (Clanza S^(™), since it showed the fastest dissolution rate. Bioequivalence of aceclofenac tablet, Airtal^(™)(Dae-Woong Pharmaceutical Co., Ltd.) and aceclofenac soft capsule, Clanza S^(™)(Korea United Pharmaceutical Co., Ltd.) was evaluated according to the guideline of KFDA. Fourteen normal male volunteers (age 20-25 years old) were divided into two groups and a randomized 2×2 cross-over study was employed. After oral administration of one tablet or capsule containing 100 ㎎ of aceclofenac, blood ws taken at predetermined time intervals and the concentration of aceclofenac in plasma wa determined with an HPLC method under UV detector. The pharmacokinetic parameters (C_(max), T_(max) and AUC_(t)) were calculated and ANOVA was utilized for the statistical analysis of parameters using logarithmically transformed AUC_(t), C_(max) and T_(max) between Airtal tablet and Clanza soft capsule were 2.89%, 0.18% and 43.0%, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.250(e.g.log(0.81) - log(1.23) and log(0.89) - log(1.14)) for AUC_(t) and C_(max), respectively. Thus, the criteria of the KDFA guidelines for the equivalence was satisfied, indicating that Clanza S^(™) soft capsule is bioequivalent to Airtal^(™) tablet.

프레탈정 (실로스타졸 100mg)에 대한 실로스탄정 (한국유나이티드 제약)의 생물학적 동등성

용철순,이경희,최진석,박병주,정세현,김용일,박상만,유봉규,이종달,최한곤 한국병원약사회 2003 병원약사회지 Vol.20 No.2

Bioequivalence of one cilostazol tablets, the Pletaal^(R)(Korea Otsuka Pharmaceutical Co., Ltd.) and Cilostan^(R)(Korea united Pharmaceutical Co., Ltd.), was evaluated according to the guideline of KFDA. Sixteen normal male volunteers(age 20~30 years old)were divided into two groups and a randomized 2×2 cross-over study was employed. After one tablet containing 100㎎ of cilostazol were orally administered, blood was taken at predetermined time intervals and the concentration of cilostazol in plasma was determined with an HPLC method using UV detector. The pharmacokinetic parameters(C_(max), T_(max) and AUC_(t)) were calculated and ANOVA was utilized for the statistical analysis of parameter. The results showed that the differences in C_(max), T_(max) and AUC_(t) between one tablet were 16.08%, 18.88% and 17.57%, respectively. The powers (1-β) for C_(max), T_(max) and AUC_(t) were 85.03%, 83.92% and 80.12%, respectively. Detectable differences(Δ) and confidence intervals were all less than 20%, and confidence interval of all the parameters were also less than 20% at the significance level(α) of 0.05. All of these parameters met the criteria of KFDA for bioequivalence, indicating that Cilostan^(R) tablet is bioequivalent to Pletaal^(R) tablet.

수도권 지역 대학병원과 재활병원의 인턴물리치료사간 인턴 만족도 비교

강순희,전수진,정민현,정은송,이범승,최용진 韓國交通大學校 2013 한국교통대학교 논문집 Vol.48 No.-

The purpose of this study was to compare internship satisfaction of intern physical therapists working in the university hospitals with that of them working in the rehabilitation hospitals in Seoul metropolitan area. The questionnaire for internship satisfaction survey that amended from vocational interest test [Strong Interest Inventory(SII)] was used to examine satisfaction of intern physical therapists and the questionnaire was used to ask general characteristics, educational and work environment. Thirty nine intern physical therapists working in university hospital and fifty nine intern physical therapists rehabilitation hospital in Seoul metropolitan area responded. Frequency analysis, χ² test and independent t-test were conducted to evaluate differences between groups about variables of internship satisfaction survey, general characteristics, work and educational environments with using the PASW 18.0 statistical program. The results of the study were as follows. There were significant differences of intern physical therapists between university hospitals and rehabilitation hospitals in overall scores of internship satisfaction and scores of all sub-items such as duty, supervision, working condition, work mates and wages. Intern physical therapists working in the university hospitals showed higher satisfaction than that of Intern physical therapists working in the rehabilitation hospitals.

鹽化物 含有梁에 따른 鐵分 腐蝕에 관한 實驗的 硏究

최진석,조철희,신용석,고송균,손순채,김정섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

As a result of separating river sand and sea sand into the corrosion increased according to the of thinnss or the coating and the Chloride Content and Corrosion of Steel Bar through the experiment, the following conclusions are obtained. 1. There was no corrosion in the case of treating the steel bar with anticorrosive among test specimens cured in the air for 60 days, corrosion was found in the test specimens not treated with anticorrosive and for 60 days of age. 2. The area of corrosion increased according to the thinnss of the coating and the chloride content wher exposed for are more than 60 days. Therefore, it was determined in general that the corrosion progressed more rapidly in water cured specimens than in air cured ones and this was due to the influence of C1_(￣) in the sea sand.

인공효소 8-azaflavin이 기질과의 반응성

최종정,이용희,이동환 한국공업화학회 2004 응용화학 Vol.8 No.2

8-azaflavin was synthesized by condensation of 4-amino-3-N-methylamino pyridune and N-methylalloxane. An oxidation-active flavin mimic contributed substantially to flavin chemistry in model systems. One of the ways of exploting oxidation-active flavin mimics could be by introducing electron-withdrawing groups into the isoalloxazine ring thus providing an electron dificient flavin. We report that 8-azaflavin show remarkably high oxidizing activities for the oxidations of N-benzyl-1,4-dihydronicotinamide(BNAH) and nitroalkanes in aqueous solution.