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Yiyu Shi,Leilei Xu,Mindong Chen,Bo Yang,Ge Cheng,Cai-e Wu,Zhichao Miao,Ning Wang,Xun Hu 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.105 No.-
In this work, the uniform Cu2O submicron-cubes were facilely synthesized by liquid phase reductionmethod. Then, the Cu2O submicron-cubes were further oxidized into Cu2O-CuO heterojunction with tunableCu2+/Cu+ ratios and CuO submicron-cubes by controlling the calcination temperature. The phasetransition period during calcination was real-time monitored by the in-situ XRD and in-situ DRIFTS. The obtained materials were investigated as the catalysts of CO oxidation. The results revealed thatthe Cu2O-CuO heterojunction catalysts performed much higher catalytic activities than the Cu2O andCuO counterparts. Because the synergistic effect of the heterojunction (Cu2+/Cu+) could increase the surfaceoxygen vacancy concentration. Furthermore, it was also found that only the Cu2O-CuO heterojunctionstructure with the appropriate Cu2+/Cu+ ratio behaved the optimum catalytic activity. The kineticstudies indicated that the apparent activation energy of CO oxidation was greatly affected by the Cu2+/Cu+ ratio. Therefore, these Cu2O-CuO submicron-cubes with heterostructure were considered as thepromising CO oxidation catalysts.
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Weiguang Gu,Hua Zhang,Yiyu Lu,Minjing Li,Shuang Yang,Jianmiao Liang,Zhijian Ye,Zhihua Li,Minhong He,Xiaoliang Shi,Fei Wang,Dong You,Weiquan Gu,Weineng Feng 대한암학회 2023 Cancer Research and Treatment Vol.55 No.3
Purpose We aimed to evaluate whether the addition of pemetrexed is effective in improving progression-free survival (PFS) in epidermal growth factor receptor (EGFR)–mutated patients with or without concomitant alterations. Materials and Methods This multicenter clinical trial was conducted in China from June 15, 2018, to May 31, 2019. A total of 92 non–small cell lung cancer (NSCLC) patients harboring EGFR-sensitive mutations were included and divided into concomitant and non-concomitant groups. Patients in each group were randomly treated with EGFR–tyrosine kinase inhibitor (TKI) monotherapy or EGFR-TKI combined with pemetrexed in a ratio of 1:1. PFS was recorded as the primary endpoint. Results The overall median PFS of this cohort was 10.1 months. There were no significant differences in PFS between patients with and without concomitant and between patients received TKI monotherapy and TKI combined with pemetrexed (p=0.210 and p=0.085, respectively). Stratification analysis indicated that patients received TKI monotherapy had a significantly longer PFS in non-concomitant group than that in concomitant group (p=0.002). In concomitant group, patients received TKI combined with pemetrexed had a significantly longer PFS than patients received TKI monotherapy (p=0.013). Molecular dynamic analysis showed rapidly emerging EGFR T790M in patients received TKI monotherapy. EGFR mutation abundance decreased in patients received TKI combined chemotherapy, which supports better efficacy for a TKI combined chemotherapy as compared to TKI monotherapy. A good correlation between therapeutic efficacy and a change in circulating tumor DNA (ctDNA) status was found in 66% of patients, supporting the guiding role of ctDNA minimal residual disease (MRD) in NSCLC treatment. Conclusion EGFR-TKI monotherapy is applicable to EGFR-sensitive patients without concomitant alterations, while a TKI combined chemotherapy is applicable to EGFR-sensitive patients with concomitant alterations. CtDNA MRD may be a potential biomarker for predicting therapeutic efficacy.
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A Novel Resource Scheduling Scheme for CoMP Systems
( Wen`an Zhou ),( Jianlong Liu ),( Yiyu Zhang ),( Chengyi Yang ),( Xuhui Yang ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.2
Coordinated multiple points transmission and reception (CoMP) technology is used to mitigate the inter-cell interference, and increase cell average user normalized throughput and cell edge user normalized throughput. There are two kinds of radio resource schedule strategies in LTE-A/5G CoMP system, and they are called centralized scheduling strategy and distributed scheduling strategy. The regional centralized scheduling cannot solve interference of inter-region, and the distributed scheduling leads to worse efficiency in the utilize of resources. In this paper, a novel distributed scheduling scheme named 9-Cell alternate authorization (9-CAA) is proposed. In our scheme, time-domain resources are divided orthogonally by coloring theory for inter-region cooperation in 9-Cell scenario [6]. Then, we provide a formula based on 0-1 integer programming to get chromatic number in 9-CAA. Moreover, a feasible optimal chromatic number search algorithm named CNS-9CAA is proposed. In addition, this scheme is expanded to 3-Cell scenario, and name it 3-Cell alternate authorization (3-CAA). At last, simulation results indicate that 9/3-CAA scheme exceed All CU CoMP, 9/3C CU CoMP and DLC resource scheduling scheme in cell average user normalized throughput. Especially, compared with the non-CoMP scheme as a benchmark, the 9-CAA and 3-CAA have improved the edge user normalized throughput by 17.2% and 13.0% respectively.
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Zhan Shu,Bo Ning,Hanlin Dong,Zheng Li,Zengxin Peng,Yiyu Yang 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.6
The bolted connections with slotted-in steel plates are basic beam-to-column connections of modern post-and-beam timber building structures. However, due to significantly pinched rotational behaviors, the moment resistance of such connections are usually ignored in design. In this study, the connection-level moment resistance is enabled for modern glulam frame structures with an innovative connection design. A pair of long steel rods with screwheads is designed to generate a force couple at the sides of the connection. The proposed connection could be considered as the key lateral force resisting component, indicating a significant reduction of lateral braces and shear walls. Specimens of the target connection were carefully designed and tested in the lab to obtain their mechanical properties and failure modes. Finite element models were established and calibrated according to the tested data. The moment-rotation curves of the new connection could be easily estimated through a fitted formula. Moreover, the suggestions to improve the proposed connection is also discussed based on the observed damage modes. Results show that the new connection could be treated as rigid moment-resisting connections while the ductility could be further improved.
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