Media Sentiment Towards Chinese Investments in Malaysia: An Examination of the Forest City Project

Yicong Wang 충남대학교 아시아여론연구소 2020 Asian journal for public opinion research Vol.8 No.3

We collected national newspaper articles on the largest Chinese investment project in Malaysia, Forest City, and examined media sentiment polarity using alternative automated sentiment analysis tools. We further checked the robustness of these results using content analysis, and consistently found that sentiment polarity for mainstream news is more volatile than independent online journalism. We also found that the sentiment polarity of Malaysian mainstream media towards Chinese investments is aligned with government interactions between the two countries. This suggests that the sentiment of Malaysian mainstream media towards Chinese investments complies with local government attitudes, while independent online media are less constrained by government control. In light of this, foreign investors looking to more effectively estimate risks should monitor both independent and mainstream media to calculate the sentiment of the host country towards their foreign direct investment projects.

Shear strength prediction of concrete-encased steel beams based on compatible truss-arch model

Yicong Xue,Chongxin Shang,Yong Yang,Yunlong Yu,Zhanjie Wang 국제구조공학회 2022 Steel and Composite Structures, An International J Vol.43 No.6

Concrete-encased steel (CES) beam, in which structural steel is encased in a reinforced concrete (RC) section, is widely applied in high-rise buildings as transfer beams due to its high load-carrying capacity, great stiffness, and good durability. However, these CES beams are prone to shear failure because of the low shear span-to-depth ratio and the heavy load. Due to the high load-carrying capacity and the brittle failure process of the shear failure, the accurate strength prediction of CES beams significantly influences the assessment of structural safety. In current design codes, design formulas for predicting the shear strength of CES beams are based on the so-called “superposition method”. This method indicates that the shear strength of CES beams can be obtained by superposing the shear strengths of the RC part and the steel shape. Nevertheless, in some cases, this method yields errors on the unsafe side because the shear strengths of these two parts cannot be achieved simultaneously. This paper clarifies the conditions at which the superposition method does not hold true, and the shear strength of CES beams is investigated using a compatible truss-arch model. Considering the deformation compatibility between the steel shape and the RC part, the method to obtain the shear strength of CES beams is proposed. Finally, the proposed model is compared with other calculation methods from codes AISC 360 (USA, North America), Eurocode 4 (Europe), YB 9082 (China, Asia), JGJ 138 (China, Asia), and AS/NZS 2327 (Australia/New Zealand, Oceania) using the available test data consisting of 45 CES beams. The results indicate that the proposed model can predict the shear strength of CES beams with sufficient accuracy and safety. Without considering the deformation compatibility, the calculation methods from the codes AISC 360, Eurocode 4, YB 9082, JGJ 138, and AS/NZS 2327 lead to excessively conservative or unsafe predictions.

Prevention of acetaminophen-induced hepatocyte injury: JNK inhibition and GSTA1 involvement

Chang Yicong,He Jingshan,Ma Bingke,Ishfaq Muhammad,Wang Jiaqi,Zhang Ruichen,Yuan Liang,Liu Jiarui,Li Changwen,Liu Fangping 대한독성 유전단백체 학회 2021 Molecular & cellular toxicology Vol.17 No.2

Background Glutathione S-transferase A1 (GSTA1) is a detoxification enzyme and a sensitive marker for hepatotoxicity. We investigated the effects of JNK inhibition on different degrees of Acetaminophen (APAP)-induced hepatocyte injury and GSTA1 expression. Objective This study aimed to investigate the role of JNK signaling pathway in APAP-induced different degrees of hepatocyte injury and its correlation with GSTA1 by inhibiting the phosphorylation of JNK by SP600125. Results 6 and 8 mM APAP induced different degrees of hepatocyte injury and apoptosis, both activated JNK signaling pathway. In contrast, JNK inhibitor significantly reduced activation of JNK and c-JUN on exposure to APAP. Meanwhile, the levels of hepatocyte injury, oxidative stress, and apoptosis obviously decreased. Importantly, GSTA1 expression was significantly increased by JNK inhibition. Conclusions JNK inhibition attenuates APAP-induced hepatocyte injury and oxidative stress and increases GSTA1 expression. Furthermore, GSTA1 may be involved in this signaling pathway for detoxification. Background Glutathione S-transferase A1 (GSTA1) is a detoxification enzyme and a sensitive marker for hepatotoxicity. We investigated the effects of JNK inhibition on different degrees of Acetaminophen (APAP)-induced hepatocyte injury and GSTA1 expression. Objective This study aimed to investigate the role of JNK signaling pathway in APAP-induced different degrees of hepatocyte injury and its correlation with GSTA1 by inhibiting the phosphorylation of JNK by SP600125. Results 6 and 8 mM APAP induced different degrees of hepatocyte injury and apoptosis, both activated JNK signaling pathway. In contrast, JNK inhibitor significantly reduced activation of JNK and c-JUN on exposure to APAP. Meanwhile, the levels of hepatocyte injury, oxidative stress, and apoptosis obviously decreased. Importantly, GSTA1 expression was significantly increased by JNK inhibition. Conclusions JNK inhibition attenuates APAP-induced hepatocyte injury and oxidative stress and increases GSTA1 expression. Furthermore, GSTA1 may be involved in this signaling pathway for detoxification.

Reference Intervals for Thyroid-Associated Hormones and the Prevalence of Thyroid Diseases in the Chinese Population

Zou Yutong,Wang Danchen,Cheng Xinqi,Ma Chaochao,Lin Songbai,Hu Yingying,Yu Songlin,Xia Liangyu,Li Honglei,Yin Yicong,Liu Huaicheng,Zhang Dianxi,Zhang Kui,Lian Xiaolan,Xu Tengda,Qiu Ling 대한진단검사의학회 2021 Annals of Laboratory Medicine Vol.41 No.1

Background: Thyroid diseases are highly prevalent worldwide, but their diagnosis remains a challenge. We established reference intervals (RIs) for thyroid-associated hormones and evaluated the prevalence of thyroid diseases in China. Methods: After excluding outliers based on the results of ultrasound screening, thyroid antibody tests, and the Tukey method, the medical records of 20,303 euthyroid adults, who visited the Department of Health Care at Peking Union Medical College Hospital from January 2014 to December 2018, were analyzed. Thyroid-associated hormones were measured by the Siemens Advia Centaur XP analyzer. The RIs for thyroid-associated hormones were calculated according to the CLSI C28-A3 guidelines, and were compared with the RIs provided by Siemens. The prevalence of thyroid diseases over the five years was evaluated and compared using the chi-square test. Results: The RIs for thyroid stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3), total thyroxine (TT4), and total triiodothyronine (TT3) were 0.71–4.92 mIU/L, 12.2–20.1 pmol/L, 3.9–6.0 pmol/L, 65.6–135.1 nmol/L, and 1.2–2.2 nmol/L, respectively. The RIs of all hormones except TT4 differed significantly between males and females. The RIs of TSH increased with increasing age. The prevalence of overt hypothyroidism, overt hyperthyroidism, subclinical hypothyroidism, and subclinical hyperthyroidism was 0.5% and 0.8%, 0.2% and 0.6%, 3.8% and 6.1%, and 3.3% and 4.7% in males and females, respectively, which differed from those provided by Siemens. Conclusions: Sex-specific RIs were established for thyroid-associated hormones, and the prevalence of thyroid diseases was determined in the Chinese population.

Cyclic tests on RC joints retrofitted with pre-stressed steel strips and bonded steel plates

Yunlong Yu,Yong Yang,Yicong Xue,Niannian Wang,Yaping Liu 국제구조공학회 2020 Structural Engineering and Mechanics, An Int'l Jou Vol.75 No.6

An innovative retrofit method using pre-stressed steel strips and externally-bonded steel plates was presented in this paper. With the aim of exploring the seismic performance of the retrofitted RC interior joints, four 1/2-scale retrofitted joint specimens together with one control specimen were designed and subjected to constant axial compression and cyclic loading, with the main test parameters being the volume of steel strips and the existence of externally-bonded steel plates. The damage mechanism, force-displacement hysteretic response, force-displacement envelop curve, energy dissipation and displacement ductility ratio were analyzed to investigate the cyclic behavior of the retrofitted joints. The test results indicated that all the test specimens suffered a typical shear failure at the joint core, and the application of externally-bonded steel plates and that of pre-stressed steel strips could effectively increase the lateral capacity and deformability of the deficient RC interior joints, respectively. The best cyclic behavior could be found in the deficient RC interior joint retrofitted using both externally-bonded steel plates and pre-stressed steel strips due to the increased lateral capacity, displacement ductility and energy dissipation. Finally, based on the test results and the softened strut and tie model, a theoretical model for determining the shear capacity of the retrofitted specimens was proposed and validated.

Polysomnography and Neuropsychological Analysis of Patients With Post-Traumatic Stress Disorder Two Years After the COVID-19 Pandemic in Wuhan

Junhua Mei,Yanjie Xu,Xue Gong,Jinmei Xu,Guohua Chen,Weiqi Chen,Yicong Wang,Zhaohong Kong,Yilong Wang,Qing Yang 대한신경정신의학회 2024 PSYCHIATRY INVESTIGATION Vol.21 No.3

Objective We used polysomnography (PSG) monitoring and neuropsychological scales to explore the characteristics of coronavirus disease-2019 (COVID-19) patients diagnosed with post-traumatic stress disorder (PTSD) in Wuhan, two years after the onset of the COVID-19 pandemic.Methods A total of 42 patients in the Sleep Medicine Center were diagnosed with insomnia between December 2021 and May 2022; they were divided into the PTSD group (patients with PTSD diagnosed with insomnia after COVID-19 infection) and the non-PTSD group (patients with insomnia without PTSD). A healthy control group was simultaneously included.Results The PTSD group was more significant than the non-PTSD group in partial manifestations of sleep disorders, neuropsychological clinical symptoms, and partial PSG data. Patients with different COVID-19 subtypes showed significant differences in the course of disease, sleep disorders, neuropsychological clinical symptoms, relevant scale scores, and PSG data analysis.Conclusion The emotional anxiety and depression of COVID-19 patients diagnosed with PTSD two years after the COVID-19 pandemic in Wuhan are more significant, and will not be self-alleviated with the passage of time. It is necessary to continue to pay attention to the PTSD symptoms and sleep psychology of COVID-19 infected patients, and take appropriate measures. Patients with severe and critical COVID-19 have more severe sleep and mental disorders, and there is a significant correlation between the duration of the disease and the severity of mental and mental disorders and sleep disorders after recovery.