Localization of Antigenic Sites at the Amino-terminus of Rinderpest Virus N Protein Using Deleted N Mutants and Monoclonal Antibody

Kang-seuk Choi,Jin-ju Nah,Young-joon Ko,Shien-young Kang,Yi-seol Joo 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

of Antigenic Sites at the Amino-terminus of Rinderpest Virus N Protein Using Deleted N Mutants and Monoclonal AntibodyKang-seuk Choi*, Jin-ju Nah, Young-joon Ko, Shien-young Kang1 and Yi-seok JooNational Veterinary Research and Quarantine service, Ministry of Agriculture and Forestry, 480 Anyang, Gyounggi 430-824, Korea1Research Institute of Veterinary Medicine, College of Veterinary Medicine, Chungbuk National University, 48 Gaeshin-dong, Heungduk-gu, Cheongju, Chungbuk 361-763, KoreaReceived April 2, 2003 / Accept July 10, 2003J. Vet. Sci. (2003), 4(2), 167-173JOURNAL OFVeterinaryScience*Corresponding author: Kang-seuk Choi National Veterinary Research and Quarantine service, Ministry of Agriculture and Forestry, 480 Anyang, Gyounggi 430-824, Korea Tel: +82-31-467-1860, Fax: +82-31-449-5882 E-mail: choiks@nvrqs.go.kr

정상 임신 기간 중 혈중 혈관내피 성장인자의 변화 및 혈소판 수와의 상관관계

설현주 ( Hyun Joo Seol ),이경욱 ( Kyong Wook Yi ),민주영 ( Joo Young Min ),오민정 ( Min Jeong Oh ),김해중 ( Hai Joong Kim ),이재관 ( Jae Kwan Lee ),허준용 ( Jun Yong Hur ),서호석 ( Ho Suk Saw ),박용균 ( Yong Kyun Park ) 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.9

목적 : 전자간증의 병리기전에 관영하는 것으로 알려진 혈관내피 성장인자 (vascular endothelial growth factor, 이하 VEGF로 약함)의 정상 임신기간동안의 혈중 변화양상을 규명하고 혈중 VEGF농도와 혈소판 수와의 상관관계를 알아보고자 하였다. 연구 방법 : 2002년 4월부터 2002년 7월까지 고려대학교 구로병원 산부인과에 내원한 33명의 정상 임산부를 대상으로 임신 초기 검사 시기 (7-8주), 모체혈청삼중표지물질 검사 Objective : The aim of the present study was to evaluate changes of vascular endothelial growth factor levels in maternal circulating blood during normal pregnancies and examine their relationship with maternal platelet counts. Methods : The 33 subjects w

Reliability Issues and Solutions in Flexible Electronics Under Mechanical Fatigue

Yi, Seol-Min,Choi, In-Suk,Kim, Byoung-Joon,Joo, Young-Chang Springer-Verlag 2018 ELECTRONIC MATERIALS LETTERS Vol.14 No.4

The risk factors for herpes zoster in bortezomib treatment in patients with multiple myeloma

Yi, Yang-Seon,Chung, Joo-Seop,Song, Moo-Kon,Shin, Ho-Jin,Seol, Young-Mi,Choi, Young-Jin,Cho, Goon-Jae,Lee, Gyeong-Won,Moon, Joon-Ho,Hwang, In-Hye,Ahn, Kang-Hee,Lee, Hee-Sun,Shin, Kyung-Hwa,Hwang, Jong Korean Society of Hematology; Korean Society of Bl 2010 Blood Research Vol.45 No.3

<P><B>Background</B></P><P>Bortezomib has significant activity in treating multiple myeloma (MM). The risk of herpes zoster (HZ) has been reported to increase significantly with bortezomib treatment, but the predisposing factors for HZ are not clear. This study is a retrospective analysis of the relevant risk factors for HZ in Korean MM patients treated with bortezomib.</P><P><B>Methods</B></P><P>Sixty-six patients with refractory or relapsed MM who underwent chemotherapy with bortezomib were included in the study. Prophylactic antiviral drugs were not used for treatment. The following parameters were reviewed: age, gender, stage and type of MM, extent of previous treatment, history of HZ, duration from the time of diagnosis to the time of bortezomib treatment initiation, and absolute lymphocyte counts (ALC) at the time of bortezomib treatment initiation.</P><P><B>Results</B></P><P>The incidence of HZ was 16.7%. There were no intergroup differences between the HZ-positive and the HZ-negative groups with regard to a history of HZ, number of previous treatments, and exposure to steroids before bortezomib treatment. The median duration from the time of MM diagnosis to the time of bortezomib treatment initiation in the HZ-positive group was significantly shorter than that in the HZ-negative group. The median ALC at the time of bortezomib initiation in the HZ-positive group was significantly lower than that in the HZ-negative group.</P><P><B>Conclusion</B></P><P>Bortezomib itself might act as a risk factor for HZ by inhibiting cell-mediated immunity, and patients with low ALC at the time of bortezomib treatment initiation were at greater risk of HZ during bortezomib treatment.</P>

Improvement of Electrical and Mechanical Properties of Ag Nanoparticulate Films by Controlling the Oxygen Pressure

Yi, Seol-Min,Lee, Ji-Hoon,Kim, Na-Rae,Oh, Sungil,Jang, Seonhee,Kim, Donghoon,Joung, Jaewoo,Joo, Young-Chang The Electrochemical Society 2010 Journal of the Electrochemical Society Vol.157 No.12

정신분열증 환자를 위한 무용/동작치료의 warm-up방법에 관한 연구

설주이,김나영 서울여자대학교 특수치료전문대학원 2007 심리치료: 다학제적 접근 Vol.7 No.2

The schizophrenic is not interested in the internal or external either, and they seem to be apathy, anhedonia, in which there is no expression of emotions, and depressed. That is why there is no consistency in expression of emotion. Also, they have some difficulties in communicating with others due to the lack of the depth and the focus of expression. Movement, Dance/Movement Therapy, which considers the movement as the expressive means, whose objective is to develop the social skills of clients and adaptation that make them to live in their community with the others. Also it is one of expressive art psychotherapies that develop and maintain the physical- self, self-esteem, and social relationship. The movements can be applied to find out the cause of their problem and to treatment. In addition, the meaning of movement is essential to Movement, Dance/Movement Therapy it is because that change in movement is the goal of treatment itself. From now on, this research is to study on theories of Delsarte, Laban, Bartenieff which influence on the Movement, Dance/Movement Therapy and to examine the characteristics of the movement in the schizophrenic based on their theories. Furthermore, the purpose of this study is to provide the fundamental data of Movement, Dance/Movement Therapy by proposing the models of warm-up methods that are critical in Movement, Dance/Movement Therapy as being of mental and physical preparation. The objectives of this research is as follow 1. Objective:what is the movement feature of the schizophrenic, which is based on theories of Delsarte, Laban, Bartenieff? 2. Objective:what is the approach of physical warm-up for the schizophrenic in Movement, Dance/Movement Therapy, which is based on theories of Delsarte, Laban, Bartenieff? The approach of this research is literature investigation. First of all, I collected and categorized the books, journals, and dissertations related to this study and I focused on Trinity theory of Delsarte, Effort from BESS of Laban, and Nine fundamental principals of Bartenieff. Also, I used the terms in the original words in English. The features of movements in schizophrenia patients based on these three theories are as below. Firstly, it is the disorganized movement. According to Trinity theory of Delsarte, there is no coordination in the head, trunk, arms, and legs which are physical, emotional, and intellectual zones. There is shot of the specialized roles of parts of body and combination of whole body in the dynamic alignment/connectivity principle of Bartenieff that says each part of body is connected and influences each others. Secondly, it is the movement uses the energy inappropriately. The patients are reported to move in lack of elements of effort which is supported by theory of Laban who believes the effort reflects the attitude, desire, and related emotions and Effort motivation theory of Bartenieff. In addition, it is diffused movement. It said that the head represents the intelligence in Trinity theory of Delsarte, however, the schizophrenic show the inappropriate connectivity in language and movement due to thinking disturbance caused by delusion. They are also known to use the indirect space that is disordered and inconsistent between direct and indirect as elements of space in effort, Laban. Insufficiency of spatial intention among Nine fundamental principals of Bartenieff brings about diffused movement as well. Finally, it is immobility. The deficiency of awakening of legs which play a role in transportation as physical active area, that of Laban’s effort, that of Batenieff’s effort motivation, and that of opportunity to express efforts is contributed. The patients also fail to weight shift that moves from one part to another part. I tried to find out the problems in movement of schizophrenia patients as symptoms of psychological and pathological, in terms of these features of movements. Furthermore, I proposed the models of warm-up methods for the therapeutic approach on basis of the theories of Delsarte, who regards the body in separated parts such as the head, trunk, hands/arms, and foots/legs, Laban’s effort, and Bartenieff’s Nine fundamental principals. It is possible to recognize the body which is the basic of movement and to have the movement experience applied by various efforts with the approaches of warm-up proposed in this study. That gives rise to modify the disorganized movement, diffused one, the movement uses the energy inappropriately, and immobility. Moreover, the schizophrenic can be aware the subject of movement, that is themselves, and their own emotions at the same time. Consequently, it can help them to have a good social relationship by being responsible to their behaviors. 본 연구는 무용/동작치료의 매개체인 움직임에 영향을 준 Delsarte, Laban, Bartenieff의 움직임 이론을 알아보고 이들의 이론을 바탕으로 정신분열증 환자들의 움직임의 특징을 정리하고자 한다. 그리고 무용/동작치료 안에서 가장 중요한 역할을 하는 정신적, 신체적 준비과정인 warm-up방법의 Model을 제시하는 것으로 현장의 무용/동작치료과정에서의 기초자료를 제공하는 데 그 목적이 있다. 연구의 과정은 문헌 고찰의 방법을 이용하였다. 본 연구와 관련 있는 도서 및 학술지 석·박사 논문을 중심으로 수집, 분류하였고 본 연구에서는 Delsarte의 삼위일체론, Laban의 BESS 중 Effort, Bartenieff의 9가지 기초 원리에 집중하고 논의하였고 움직임 이론의 용어는 원어를 사용하였다. Delsarte, Laban, Bartenieff의 움직임 이론을 통한 정신분열증 환자의 움직임의 특징은 첫째, 와해된 움직임이다. 둘째, 적절한 에너지 사용이 부적절한 움직임이다. 셋째, 산만한 움직임이다. 넷째, 부동성의 움직임이다. 신체를 머리, 몸통, 팔/손, 다리/발로 나누어 본 Delsarte의 삼위일체론을 바탕으로 Laban의 Effort, Bartenieff의 9가지 움직임 원리를 이용하여 warm-up방법의 Model을 제시하였다. 본 연구에서 제시한 warm-up방법을 통해 움직임의 기초 수단인 신체 인식, 다양한 에포트를 적용한 움직임경험을 통해서 정신분열증 환자들의 와해된 움직임, 에너지 사용이 부적절한 움직임, 산만한 움직임, 부동성 움직임의 변화를 줄 수 있고 움직임의 주체가 자신임을 인식하게 되며 동시에 자기 감정을 인식하고 더 나아가 자신의 행동의 책임감을 증가시킬 수 있어 움직임을 통해 긍정적인 대인관계를 맺는데 도움이 될 것이라 기대한다.

잉크젯 프린팅된 Cu 박막의 응력해소를 통한 전기적 특성 개선

이설민,주영창,Yi, Seol-Min,Joo, Young-Chang 한국마이크로전자및패키징학회 2014 마이크로전자 및 패키징학회지 Vol.21 No.4

미래형 유연소자 개발 시 비용감소 및 공정적합성 개선을 위해 동박을 잉크젯 프린팅법을 이용해 공중합체 유연기판 상 형성하고, 전기적 특성에 열처리 분위기가 미치는 영향을 확인하기 위해 3 종류의 환원분위기에서 열처리를 진행하여 보았다. 그 결과 200도의 낮은 온도에서 환원 특성이 뛰어난 포름산 분위기에서 전도체 수준의 비저항은 얻을 수 있었으나, 열처리 시 발생하는 응력으로 인해 발생된 표면균열에 기인해 그 값이 기존 동박에 비해 매우 높았다. 이에 비정질재료에서 응용되는 응력해소법을 응용하여 표면균열을 억제한 결과 230도 열처리 시 기존 열처리 방법에서는 $7.4{\mu}{\Omega}cm$의 비저항을 보이나, 응력해소를 통한 표면 균열이 억제된 시편에서는 $3.4{\mu}{\Omega}cm$의 비저항 값을 얻을 수 있었다. 특히 등온열처리에 의한 응력해소 효과를 확인하기 위해 동일 온도에서 등온시간 없이 열처리를 진행한 결과, 표면균열이 억제되지 못함을 확인할 수 있었다. Using flexible bismaleimide-triazine co-polymer as a substrate, inkjet-printed Cu films were also investigated for low-cost and process feasibility of flexible electronics. After annealing at $200^{\circ}C$ for 1 h under various reducing ambient, surface color was changed to red and electrical resistivity was decreased to the level of conductor under formic acid ambient. However, its resistivity was much higher than conventional copper films due to surface crack. In order to reduce the residual film stress after annealing, additional isothermal treatment was inserted before anneal hiring the stress relaxation applied in processes of amorphous materials. As a result, no surface crack was observed and electrical resistivity of $3.4{\mu}{\Omega}cm$ was measured after annealing at $230^{\circ}C$ with stress relaxation while electrical resistivity of $7.4{\mu}{\Omega}cm$ was observed after normal annealing without relaxation. The effect of stress relaxation was also confirmed by observing surface crack after decreasing the relaxation time to 0 min.

사이버대학교 공학계열 학생들의 숙달접근목표지향성, 과제가치, 자기조절학습전략의 학업만족도와 학업성취도예측력 규명

주영주(Young Ju Joo),정애경(Ae Kyung Chung),설현남(Hyunnam Seol),이상회(Sang Hoi Yi) 대한전자공학회 2012 電子工學會論文誌 IE (Industry electronics) Vol.49 No.2

The purpose of this study is to verify the prediction of mastery-approach goal orientation, task value, and self-regulated learning strategy on academic satisfaction and achievement of cyber engineering university students. For this study, 219 engineering students of H cyber university who enrolled in the spring semester of 2011 was chosen and completed web surveys. A hypothetical model proposed included mastery-approach goal orientation, task value, and self-regulated learning strategy as predictors, and academic satisfaction and achievement as criteria variables. The results of this study through multiple regression analysis indicated that task value(β=.401) and self-regulated learning strategy(β=.401) predicted significantly on academic satisfaction. In addition, self-regulated learning strategy(β=.301) and mastery-approach goal orientation(β=.196) predicted significantly on academic achievement. The result of this study suggested that mastery-approach goal orientation, task value, and self-regulated learning strategy should be considered for improving academic satisfaction and achievement in cyber engineering education. 본 연구는 사이버대학교 공학계열 학생들의 숙달접근목표지향성, 과제가치, 자기조절학습전략의 학업만족도와 학업성취도에 대한 예측력을 규명하는 데 있다. 이를 위해 H 사이버대학교의 2011년 1학기 정보통신학과의 세 과목을 등록한 219명을 대상으로 웹서베이를 실시하였으며, 수집된 데이터를 바탕으로 숙달접근목표지향성, 과제가치, 자기조절학습전략을 예측변인으로, 학업만족도와 학업성취도를 결과변인으로 설정하여 중다회귀분석을 실시하였다. 연구 결과, 과제가치(β=.401)와 자기조절학습전략(β=.401)은 학업만족도를 유의하게 예측하였으며, 자기조절학습전략(β=.301)과 숙달접근목표지향성(β=.196)은 학업성취도를 유의하게 예측하였다. 이와 같은 연구결과를 토대로 사이버대학교 공학계열 학생들의 학업만족도와 성취도를 향상시키기 위해 숙달접근목표지향성, 과제가치, 자기조절학습전략을 높이는 구체적인 증진방안이 고려되어야 할 것이다.

Symposium 5 : Pharmacogenomics and Drug Discovery ; Clinical pharmacology and pharmacogenomics

( In Jin Jang ),( Joo Youn Cho ),( Hyeong Seol Lim ),( So Young Yi ),( Jae Yong Chung ),( Sang Goo Shin ) 한국생화학분자생물학회 (구 한국생화학회) 2003 생화학분자생물학회 춘계학술발표논문집 Vol.2003 No.-

Surfactin from <i>Bacillus subtilis</i> displays anti-proliferative effect via apoptosis induction, cell cycle arrest and survival signaling suppression

Kim, Seo-young,Kim, Joo Young,Kim, Seol-Hee,Bae, Hyun Jin,Yi, Hwaseon,Yoon, Sang Hong,Koo, Bon Sung,Kwon, Moosik,Cho, Jae Youl,Lee, Choong-Eun,Hong, Sungyoul North-Holland Pub 2007 FEBS letters Vol.581 No.5

<P><B>Abstract</B></P><P>The effect of surfactin on the proliferation of LoVo cells, a human colon carcinoma cell line, was examined. Surfactin strongly blocked the proliferation of LoVo cells by inducing pro-apoptotic activity and arresting the cell cycle, according to several lines of evidence on DNA fragmentation, Annexin V staining, and altered levels of poly (ADP-ribose) polymerase, caspase-3, p21<SUP>WAF1/Cip1</SUP>, p53, CDK2 and cyclin E. The anti-proliferative activity of surfactin was mediated by inhibiting extracellular-related protein kinase and phosphoinositide 3-kinase/Akt activation, as assessed by phosphorylation levels. Therefore, our data suggest that surfactin may have anti-cancer properties as a result of its ability to downregulate the cell cycle and suppress its survival.</P>