Effects of Aqueous Extract of Schizandrae Fructus on Lead-Induced Change of Monoamine Neurotransmitters in Hippocampus

Zhao, Rong Jie,Zhao, Zheng Lin,Zhao, Xiu Feng,Zhao, Guang Wen,Li, Meng Quan,Wu, Yi Yan,Li, Jing Qiu,Guan, Li Xin,Kim, Sang-Chan The Korean Medicine Society for the Herbal Formula 2009 大韓韓醫學方劑學會誌 Vol.17 No.2

The effects of aqueous extract of Schizandrae Fructus (AESC) on lead (Pb)-induced changes of monoamine neurotransmitters in the hippocampus (HIP) of adult rats were investigated. Male Sprague-Dawley rats were received intraperitoneal (i.p.) administration of Pb acetate (5 mg/kg/d) for 28 days and sacrificed 7 days after the last administration. Concentrations of norepinephrine (NE), dopamine (DA), serotonin (5-HT), 5-hydroxyindole acetic acid (5-HIAA) in HIP were measured by HPLC. There were significant decreases of NE, DA, 5-HT and 5-HIAA in Pb treated rats (P < 0.05), while pretreatment with AESC (100 mg/kg/d or 300 mg/kg/d, p.o., 2 h before Pb) greatly inhibited the decrease of monoamine transmitters, respectively (P < 0.05). Also, AESC (300 mg/kg/d) significantly increased the reduction of glutathione contents and superoxide dismutase activities in HIP induced by chronic Pb. These results suggest that AESC ameliorates Pb-induced depletion of monoamine neurotransmitters in HIP through its antioxidant activity.

COVID-19 주요 연구 동향 분석 : SCOPUS DB를 중심으로

YI ZHAO,손진현 대한산업경영학회 2023 산업융합연구 Vol.21 No.2

본 논문의 목적은 COVID-19의 최근 주요 연구 동향을 파악하는데 있다. 이에 Elsevier에서 제공하는 해외 학술 DB 인 SCOPUS를 활용하여 최근 3년간(2020~2022) COVID-19의 연구 동향을 파악하고자 한다. 빈도 분석 결과, covid가 7,248건, pandemic이 4,974건, study가 3,313건, research가 2,137건, crisis가 1,777건 순으로 그 중요도가 나타났다. 트렌드 분석결과, covid와 pandemic은 꾸준하게 연구가 진행되고 있으나, study, research, crisis는 최근 들어 연구가 다 소 감소하고 있는 것으로 나타났다. LDA 토픽 모델링 분석 결과, 중요한 토픽은 ‘covid19, pandemic’ 인 것으로 나타났다. 이는 COVID-19에 대한 연구가 일상생활뿐만이 아니라 기업이나 조직에서도 필요하기 때문에 의학 이외의 다른 학문 분야 에서도 중요하다는 것을 보여준다. 특히 COVID-19가 그 어느 때보다도 중요해지는 상황에서 COVID-19의 연구가 미치는 영향 및 파급효과에 관한 관심이 지속적으로 이루어질 것으로 보인다. The purpose of this study is to identify the major research trends of COVID-19 in recent times. In addition, we would like to use SCOPUS, an overseas academic database provided by Elsevier, to understand the research trends of COVID-19 in the last three years (2020-2022). As a result of frequency analysis, covid 7,248 cases, pandemic 4,974 cases, study 3,313 cases, research 2,137 cases, crisis 1,777 cases appeared in order of importance. As a result of the trend analysis, we found that studies on covid and pandemic are progressing steadily, but those on study, research, and crisis have decreased somewhat recently. As a result of LDA topic modeling analysis, the important topics were found to be 'covid19, pandemic'. This shows that research on COVID-19 is important not only in everyday life, but also in companies and organizations, and therefore in other academic fields besides medicine. When (the study of)COVID-19 becomes more important than ever, there seems to be an ongoing interest in the impact and ramifications of COVID-19 research.

Values of Three Different Preoperative Regimens in Comprehensive Treatment For Young Patients with Stage Ib2 Cervical Cancer

Zhao, Yi-Bing,Wang, Jin-Hua,Chen, Xiao-Xiang,Wu, Yu-Zhong,Wu, Qiang Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

Objective: To compare the clinical efficacy of concurrent chemoradiotherapy, neoadjuvant chemotherapy, and intracavity brachytherapy in comprehensive treatment for young patients with stage Ib2 cervical cancer. Methods: One hundred and twelve young patients with stage Ib2 cervical cancer were enrolled retrospectively in our hospital from January 2003 to June 2005. They were categorized into three groups according to preoperative regimens, including the concurrent chemoradiotherapy group (Group 1, n=38), the neoadjuvant chemotherapy (Group 2, n=49), and the intracavity brachytherapy group (Group 3, n=25). Radical hysterectomy was performed following these regimens. Chemotherapy and radiotherapy were given according to pelvic lymph node metastasis, deep cervical stromal invasion, intravascular cancer emboli, histological grading, vaginal stump and positive surgical margin. Results: The cancer disappearance and superficial muscle invasion rates were statistically significantly better in the concurrent chemoradiotherapy group than in the other two groups (P<0.01). No statistically significant difference was noted in the deep muscle invasion rate, surgical time and intraoperative blood loss among three groups, but significantly more postoperative complications occurred in the concurrent chemoradiotherapy group. The 2-year pelvic recurrence was statistically significantly lower in the concurrent chemoradiotherapy group compared to other two groups, while the 5-year survival was higher. Conclusion: Concurrent chemoradiotherapy is efficacious for young patients with stage Ib2 cervical cancer.

Experimental and Simulation Study of PEMFC based on Ammonia Decomposition Gas as Fuel

Zhao, Jian Feng,Liang, Yi Fan,Liang, Qian Chaos,Li, Meng Jie,Hu, Jin Yi The Korean Electrochemical Society 2022 Journal of electrochemical science and technology Vol.13 No.1

Compared with hydrogen, ammonia has the advantages of high gravimetric hydrogen densities (17.8 wt.%), ease of storage and transportation as a chemical hydrogen storage medium, while its application in small-scale on-site hydrogen production scenarios is limited by the need for complex separation equipment during high purity hydrogen production. Therefore, the study of PEMFC, which can directly utilize ammonia decomposition gas, can greatly expand the application of fuel cells. In this paper, the output characteristics, fuel efficiency and the variation trend of hydrogen concentration and local current density in the anode channel of fuel cell with the output voltage of PEMFC fueled by ammonia decomposition gas were studied by experiment and simulation. The results indicate that the maximum output power of the hybrid fuel decreases by 9.6% compared with that of the pure hydrogen fuel at the same inlet hydrogen equivalent. When the molar concentration of hydrogen in the anode channel is less than 0.12, the output characteristics of PEMFC will be seriously affected. Employing ammonia decomposition gas as fuel, the efficiency corresponding to the maximum output power of PEMFC is approximately 47%, which is 10% lower than the maximum efficiency of pure hydrogen.

Distal Demonstrative Hitlo in Taiwanese Southern Min

( Yi Jing Zhao ) 한국언어정보학회 2007 학술대회 논문집 Vol.2007 No.-

This article investigates the use of distal demonstrative Hitlo in Taiwanese Southern Min (TSM) from a discourse-pragmatic perspective. The analysis is based on a 5-hour corpus of spoken data, including daily conversations, radio interviews, TV drama series, and some random examples. A total of 172 tokens of Hitlos are identified in the data. They can be divided into six categories according to their functions: firstly, exophoric usage, those Hitlos which refer to an object non-linguistically which can be identified in the immediate situation; secondly, endophoric usage, those which refer to an element textually; thirdly, referent introducing function, those which can be used to introduce a new but identifiable referent into the conversation (the referent usually has topical importance); fourthly, hedging expression, those which serve as a marker of imprecision; fifthly, a condition introducing marker, those which function as an indicator of the coming of a conditional sentence; finally, pause fillers, those which help speakers to manage speech turn or indicate the mental states In addition, an interactive function which Hitlo is found to serve will be discussed. Moreover, a grammaticalizational process involving semantic bleaching which Hitlo is probably undergoing is revealed in general. Finally, a filled demonstrative principle, stating that it may be a universal phenomenon to use demonstratives as filled pause will be proposed.

A Study of Night Tourism Based on the Tourist Perceived Value:

Zhao Yi jing,Chen Nan,Jeong Gang Hoan 한국상품학회 2016 商品學硏究 Vol.34 No.6

Night tourism generated under the background of tourists’ consumption demand transformed and 24 hours economy development. This study researched the classification of night tourism products in recent and selected Chinese most representative example which called Zigong Lantern Festival to research the tourist perceived value effect on behavior intention at night tourism. After the survey, 308 questionnaires were collected and examined by SPSS 18.0. The findings indicate that multidimensional value-including “Price appropriate perception”, “Condition value”, “Emotion value”, “Culture epistemic value” and “Social value” enables organizers to better understand visitors’ evaluative perceptions regarding lantern festival and night tourismproducts.

Scrotal Sparganosis Mimicking Scrotal Teratoma in an Infant

Yi-Ming Zhao,Hao-Chuan Zhang,Zhong-Rong Li,Hai-Yan Zhang 대한기생충학열대의학회 2014 The Korean Journal of Parasitology Vol.52 No.5

A Study on Ritual Resistance of V-Tuber Fans

Zhao-Yi Xu,Won-Ho Choi 한국콘텐츠학회 2022 한국콘텐츠학회 ICCC 논문집 Vol.2022 No.12

Children`s Acquisition of Demonstrative Pronouns in Mandarin Chinese

( Yi Jing Zhao ) 한국언어정보학회 2007 학술대회 논문집 Vol.2007 No.-

This paper investigates children``s comprehension and production of demonstrative pronouns (DPs), ``zhege`` (this) and ``nage`` (that), in Mandarin Chinese. Subjects are children of ages three, four, five and six. Based on the results of the present experiment, children``s developmental stages and the corresponding age grading are provided. Also, the present study incorporates a physical clue into the experiment. The result suggests that in the acquisition of deixis children rely highly on physical context to work out the meaning distinction. In addition, Piaget``s egocentrism hypothesis and H. Clark``s marking hypothesis are examined in the study. The result seems to support the egocentrism hypothesis. Subjects under the age of six do fail to shift the deictic center when they and the experimenter have a different perspective. As for the marking hypothesis, the study seems to challenge the hypothesis. The result shows that children actually performed better on the marked term ``zhege`` than the unmarked member ``nage``.

Lifetime Prediction and Aging Behaviors of Nitrile Rubber Under Operating Environment of Transformer

Yi-Hua Qian,Hong-zhao Xiao,Ming-hao Nie,Yao-hong Zhao,Yunbai Luo,Shu-ling Gong 대한전기학회 2018 Journal of Electrical Engineering & Technology Vol.13 No.2

Based on the actual operating environment of transformer, the aging tests of nitrile butadiene rubber (NBR) were conducted systematically under four conditions: in air, in transform oil, under compression in air and under compression in transform oil to studythe effect of high temperature, transform oil and compression stress simultaneously on the thermal aging behaviors of nitrile butadiene rubber and predict the lifetime. The effects of liquid media and compression stress simultaneously on the thermal aging behaviors of nitrile butadiene rubber were studied by using characterization methods such as IR spectrosc-opy, thermogravimetric measurements, Differential Scanning Calorimetry (DSC) measurements and mechanical property measurements. The changes in physical properties during the aging process were analyzed and compared. Different aging conditions yielded materials with different properties. Aging at 70°C under compression stress in oil, the change in elongation at break was lower than that aging in oil, but larger than that aging under compression in air. The compression set or elongation at break as evaluation indexes, 50% as critical value, the lifetime of NBR at 25°C was predicted and compared. When aging under compression in oil, the prediction lifetime was lower than in air and under compression in air, and in oil. It was clear that when predicting the service lifetime of NBR in oil sealing application, compression and media liquid should be involved simultaneously. Under compression in oil, compression set as the evaluation index, the prediction lifetime of NBR was shorter than that of elongation at break as the evaluation index. For the life prediction of NBR, we should take into account of the performance trends of NBR under actual operating conditions to select the appropriate evaluation index.