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Inhibitory Activity of Plantago major L. on Angiotensin I-converting Enzyme
Nguyen Xuan Nhiem,김영호,Bui Huu Tai,Phan Van Kiem,Chau Van Minh,Nguyen Xuan Cuong,Nguyen Huu Tung,Vu Kim Thu,Trinh Nam Trung,Hoang Le Tuan Anh,조성훈,장해동,권영인 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.3
Eight compounds were isolated from methanol extract of Plantago major L. leaves and investigated for their ability to inhibit angiotensin I-converting enzyme activity. Among them, compound 1 showed the most potent inhibition with rate of 28.06 ± 0.21% at a concentration of 100 μM. Compounds 2 and 8 exhibited weak activities. These results suggest that compound 1 might contribute to the ability of P. major to inhibit the activity of angiotensin I- converting enzyme.
Chemical components from the leaves of Ardisia insularis and their cytotoxic activity
Nguyen Thi Hong Van,김승현,Trinh Anh Vien,Phan Van Kiem,Chau Van Minh,Nguyen Xuan Nhiem,Pham Quoc Long,Luu Tuan Anh,김난영,박선주 대한약학회 2015 Archives of Pharmacal Research Vol.38 No.11
One new oleanane triterpene glycoside, ardinsuloside(1), and twelve known compounds, demethoxybergenin(2), norbergenin (3), bergenin (4), 4-O-galloylbergenin(5), quercitrin (6), myricitrin (7), myricetin 3-O-(300-O-galloyl)-a-L-rhamnopyranoside (8), desmanthine-2 (9), epicatechin3-O-galloyl ester (10), 30-methoxyepicatechin 3-Ogalloylester (11), gallic acid (12), and methyl galloate (13)were isolated from the leaves of Ardisia insularis. Theirstructures were established on the basis of spectral and chemicalevidence, which were in agreement with those reportedin literature. The cytotoxic activities of these compounds wereevaluated on three cancer cell lines namely A-549 (humanlung cancer), HT-29 (Human colon adenocarcinoma), andOVCAR (human ovarian carcinoma). The results revealedthat compound 1 inhibited A-549, HT-29, and OVCAR celllines with IC50 values of 8.5 ± 1.2, 16.4 ± 3.1, and13.6 ± 2.4 lM, respectively. The remaining compoundshowed weak cytotoxic activity. This result indicated thatcompound 1 could be useful in the treatment of cancer disease.
Nguyen Hoang Loc,Truong Thi Phuong Lan,Nguyen Duc Huy,Nguyen Ngoc Luong,Hoang Tan Quang,Trinh Huu Tan,Le Thi Anh Thu,Nguyen Xuan Huy 한국식물생명공학회 2019 JOURNAL OF PLANT BIOTECHNOLOGY Vol.46 No.3
The aim of this study is to evaluate the effect of yeast extract (YE) and salicylic acid (SA) on the expression of curcuminoid-biosynthesis genes (CzDCS and CURS1-3), and accumulation of curcumin in Curcuma zedoaria cell cultures. The results showed that, in cells treated with YE or SA, the expression levels of curcuminoid genes were 1.14- to 3.64-fold higher than the control (untreated cells), in which the YE exhibited a stronger effect in comparison with SA. Curcumin accumulation also tended to be similar to gene expression, curcumin contents in YE- or SA-treated cells were 1.61- to 2.53-fold higher than the control. The SA treatment at the fifth day of culture stimulated the curcumin accumulation and expression in all four genes compared to that at the beginning. While the YE treatments gave different results, the CzCURS1 and CzCURS3 genes were expressed strongly in cells that were treated at the beginning. However, the CzDCS and CzCURS2 genes showed the opposite expression pattern, they were activated strongly in the treatments at day five of the culture. However, the content of curcumin reached its maximum value on the fifth day of culture in all investigations.
INVESTIGATION OF THE THEORY OF RHEODYNAMIC LUBRICATION AND ITS APPLICATIONS
Tuan, NGUYEN Anh,Toan, NGUYEN Xuan ENGINEERING TRIBOLOGY RESEARCH INSTITUTE KYUNGPOOK 1998 INTERNATIONAL SYMPOSIUM ON HIGH PERFORMANCE OF TRI Vol.1998 No.-
In the study of the lubricant flow and characteristics of the rheodynamic lubrication mechanism, the models of Reiner-Rivlin, Maxwell and Bingham bodies are examined and used. the evaluation of rheodynamic lubrication mechanism requires the solution of generalized Reynolds equations, which are incorporated by the nonlinear behavior of lubricant. In this paper, the authors present a form of Navier-Stokes equations for the case of Bingham fluid. In pratice, this problem consists the lubrication mechanism using the grease. The finite elements method is used for solving these equations. The results are presented on the fluid flow as some regions of film thickness of lubricant, determining the boundary conditions of Reynolds equation and the exact calculation of rheodynamic contact.
Nhiem, Nguyen Xuan,Kiem, Phan Van,Minh, Chau Van,Tai, Bui Huu,Cuong, Nguyen Xuan,Thu, Vu Kim,Anh, Hoang Le Tuan,Jo, Sung-Hoon,Jang, Hae-Dong,Kwon, Young-In,Kim, Young Ho The Pharmaceutical Society of Japan 2010 Chemical & pharmaceutical bulletin Vol.58 No.10
<P>One new monoterpenoid glycoside, myresculoside (<B>1</B>), and eleven known compounds, were isolated from methanol extract of <I>Myrica esculenta</I> leaves by repeated column chromatography. The effects of these compounds on angiotensin I-converting enzyme (ACE) inhibition were investigated. Compounds <B>3</B> and <B>4</B> showed the most potent ACE inhibition with rates of 29.97% and 25.63% at concentration of 100 μ<SMALL>M</SMALL>, respectively. Compounds <B>5</B>, <B>6</B>, and <B>11</B> showed weak activity with inhibitory rates of 0.07—1.41% at concentration of 100 μ<SMALL>M</SMALL>.</P>
Income Distribution and Factors Affecting the Bank’s Stability
Viet Xuan TRINH(Viet Xuan TRINH ),Du Kim DO(Du Kim DO),Anh Thi Lan NGUYEN(Anh Thi Lan NGUYEN ) 한국유통과학회 2022 유통과학연구 Vol.20 No.9
Purpose: Research on banking sustainability plays an important role in helping banks understand the level of risk in different types of companies. Therefore, this study was conducted to determine the factors affecting the sustainability of Joint Stock Commercial Banks in Vietnam. Research design, data and methodology: The following theories, the factors affecting the bank's sustainability include: Business model diversification (income diversification), bank size, loan ratio, and net interest margin. Data was collected from Joint Stock Commercial banks in Vietnam from 2015 to 2019. With GLS model on panel data with banks listed on Vietnam stock exchange. Results: The analysis results show that net interest income has a positive impact on the sustainable business results of banks through the rate of return on total assets (ROA). The non-interest income hasn’t impact on bank stability. From this result, there aren’t positive signs of income diversification in banks. At the same time, with the obtained results, the study also provides a policy implication for banks. Conclusions: The study also provides some policy implications to improve the bank stability. Diversifying income in banks is necessary, but how to make it influential banks has not yet been done. Therefore, the adjustments in non-interest business activities need to be carefully considered by banks.
Truong Xuan NGUYEN,Khai Quang LUU,Thien Thuan Hoang NGUYEN,An Van HA,Han Bao Huynh NGUYEN,Anh Nhu Thi BUI 한국유통과학회 2018 KODISA ICBE (International Conference on Business Vol.2018 No.-
This study to explore and examines the factors affecting 4.0 industrial adoption in enterprises in Ho Chi Minh City. The research model based on the two main research theories is the Technology Adaptation Model (Davis, 1989) and the Theory of Planned Behavior (Ajzen, 1991), and previous literature on technology 4.0 to build conceptual models which appropriate to the research content. Both qualitative and quantitative research methods are applied in the study. Qualitative research is conducted first in the form of in-depth interviews to adjust the conceptual model. Quantitative research was then used to verify the conceptual model. Samples taken by the non-probability method and convenience sampling technical through the official questionnaire for 380 small and medium enterprises have been applying elements of industry 4.0. The results show that in addition to the effect of Intent to Use on Use decision, in the group of independent variables affecting Perceived Usefulness of the business, turning Perceived Saving Cost has the strongest impact, and in the group of independent variables which influence Intent to Use, the Business Resource variable has the strongest impact.
Phan Thi Anh Dao,Nguyen Xuan Hai,Nguyen Trung Nhan,Tran Le Quan,Nguyen Thi Thanh Mai 한국생약학회 2012 Natural Product Sciences Vol.18 No.1
Among 90 Vietnamese medicinal plant extracts investigated for their antioxidant activity by DPPH assay at various concentrations from 10 - 100 ?g/mL, 67 showed an inhibition rate over 50% at 100 ?g/mL; 47 had greater than 50% inhibition at 50 ?g/mL; 17 showed over 50% inhibition at 25 ?g/mL. 8 extracts which exhibited strong inhibitory activity more than 50% inhibition at 10 ?g/mL were further tested for lipid peroxidation inhibition by TBA assay. They displayed activity with IC50 values from 30.6 to 158.9 ?g/mL. Until now, this is the first report on antioxidant activity of the female flower of Borassus flabellifer, and the stem of Combretum latifolium, Embelia ribes, Spatholobus parviflorus, and Tetrastigma erubescens. Fractionations of the EtOAc extract prepared from S. parviflorus led to the isolation of protocatechuic acid (1), ferulic acid (2), epicatechin (3), and gallic acid (4). These compounds showed significant DPPH inhibitory activity with IC50 values from 6.5 to 23.6 ?M.
( Thuy Duong Nguyen ),( Boi An Tran ),( Ke Oanh Vu ),( Anh Son Nguyen ),( Anh Truc Trinh ),( Gia Vu Pham ),( Thi Xuan Hang To ),( Thanh Thao Phan ) 한국부식방식학회(구 한국부식학회) 2020 Corrosion Science and Technology Vol.19 No.2
This work examined the corrosion protection performance of benzoate loaded hydrotalcite/graphene oxide (HT/GO-BZ) for carbon steel. HT/GO-BZ was fabricated by the co-precipitation method and characterized by infrared spectroscopy, X-ray diffraction, and scanning electronic microscopy. The corrosion inhibition action of HT/GO-BZ on carbon steel in 0.1 M NaCl solution was evaluated by electrochemical measurements. The benzoate content in HT/GO-BZ was determined by UV-Vis spectroscopy. Subsequently, the effect of HT/GO-BZ on the corrosion resistance of the water-based epoxy coating was investigated by the salt spray test. The obtained results demonstrated the intercalation of benzoate and GO in the hydrotalcite structure. The benzoate content in HT/GO-BZ was about 16%. The polarization curves of the carbon steel electrode revealed anodic corrosion inhibition activity of HT/GO-BZ and the inhibition efficiency was about 95.2% at a concentration of 3g/L. The GO present in HT/GO-BZ enhanced the inhibition effect of HT-BZ. The presence of HT/GO-BZ improved the corrosion resistance of the waterborne epoxy coating.