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      • KCI등재

        Kinetic Model for the Phase Transformation of High‑Strength Steel Under Arbitrary Cooling Conditions

        Hao Zhao,Xiuli Hu,Junjia Cui,Zhongwen Xing 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.2

        To meet the demands of energy conservation and security improvement, high-strength steel (HSS) is widely used to producesafety-related automotive components. In addition to fully high-strength parts, HSS is also used to manufacture componentswith tailored properties. In this work, a computational model is presented to predict the austenite decomposition into ferrite,pearlite, bainite and martensite during arbitrary cooling paths in HSS. First, a kinetic model for both diffusional and martensitetransformations under isothermal or non-isothermal with constant cooling rate cooling conditions is proposed basedon the well-known Johnson–Mehl–Avrami–Kolmogorov and Kamamoto models. The model is then modified for arbitrarycooling conditions through the introduction of the effects of the cooling rate, and the influence of diffusional transformationson martensite transformation is considered. Next, the detailed kinetics parameters are identified by fitting experimental datafrom BR1500HS steel. The model is further verified by several experiments conducted outside of the fit domain. The resultsobtained by calculation are found to be in good agreement with the corresponding experimental data, including the transformationhistories, volume fraction microconstituents and Vickers hardness. Additionally, the model is also implementedas a subroutine in ABAQUS to simulate a tailored-strength hot stamping process of HSS, and the results are consistent withthe test data. Thus, this computational model can be used as a guideline to design manufacturing processes that achieve thedesired microstructure and material properties.

      • KCI등재

        Preparation and Investigation of Ulex Europaeus Agglutinin IConjugated Liposomes as Potential Oral Vaccine Carriers

        KeXin Li,DaWei Chen,XiuLi Zhao,HaiYang Hu,ChunRong Yang,DaHai Pang 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.11

        We prepared and optimized Ulex europaeus agglutinin I (UEAI)-modified Bovine serum albumin (BSA)-encapsulating liposomes (UEAI-LIP) as oral vaccine carriers and examined the feasibility of inducing systemic and mucosal immune responses by oral administration of UEAILIP. The prepared systems were characterized in vitro for their average size, zeta potential,encapsulation efficiency (EE%) and conjugation efficiency (CE%). In vitro release studies indicated that the presence of UEAI around the optimized liposomes was able to prevent a burst release of loaded BSA and provide sustained release of the encapsulated protein. In vivo immune-stimulating results in KM mice showed that BSA given intramuscularly generated systemic response only but both systemic and mucosal immune responses could be induced simultaneously in the groups in which BSA-loaded liposomes (LIP) and UEAI-LIP were administered intragastrically. Furthermore, the modification of UEAI on the surface of liposomes could further enhance the IgA and IgG levels obviously. In conclusion, this study demonstrated the high potential of lectin-modified liposomes containing the antigen as carriers for oral vaccine.

      • SCOPUSKCI등재SSCISCIE

        Influencing Factors of High PTSD Among Medical Staff During COVID-19: Evidences From Both Meta-analysis and Subgroup Analysis

        Qi, Guojia,Yuan, Ping,Qi, Miao,Hu, Xiuli,Shi, Shangpeng,Shi, Xiuquan Occupational Safety and Health Research Institute 2022 Safety and health at work Vol.13 No.3

        Background: PTSD (Post-traumatic stress disorder, PTSD) had a great impact on health care workers during the COVID-19 (Corona Virus Disease 2019, COVID-19). Better knowledge of the prevalence of PTSD and its risk factors is a major public health problem. This study was conducted to assess the prevalence and important risk factors of PTSD among medical staff during the COVID-19. Methods: The databases were searched for studies published during the COVID-19, and a PRISMA (preferred reporting items for systematic review and meta-analysis) compliant systematic review (PROSPERO-CRD 42021278970) was carried out to identify articles from multiple databases reporting the prevalence of PTSD outcomes among medical staff. Proportion random effect analysis, I<sup>2</sup> statistic, quality assessment, subgroup analysis, and sensitivity analysis were carried out. Results: A total of 28 cross-sectional studies and the PTSD results of doctors and nurses were summarized from 14 and 27 studies: the prevalences were 31% (95% CI [confidence interval, CI]: 21%-40%) and 38% (95% CI: 30%-45%) in doctors and nurses, respectively. The results also showed seven risks (p < 0.05): long working hours, isolation wards, COVID-19 symptoms, nurses, women, fear of infection, and pre-existing mental illness. Two factors were of borderline significance: higher professional titles and married. Conclusion: Health care workers have a higher prevalence of PTSD during COVID-19. Health departments should provide targeted preventive measures for medical staff away from PTSD.

      • KCI등재

        A high-resolution timescale for the Miocene Shanwang diatomaceous shale lagerstätte (China): development of Wavelet Scale Series Analysis for cyclostratigraphy

        Jifeng Yu,Xinlong Pang,Wenzhao Fu,Jason Hilton,Mingmei Liang,Zongkai Jiang,Xiuli Zhao,Wenyan Qiao,Suo Shi,Diandong Zhang,Huitao Cao,Haibo Jia,Yadong Wang,Xiaoke Hu,Rui Zhang 한국지질과학협의회 2021 Geosciences Journal Vol.25 No.5

        The Miocene aged Shanwang Formation from the Shanwang National Geopark in China represents a succession of lacustrine diatomaceous shales containing an abundant and diverse biota with lagerstätte fossilization of soft tissues. To date, the Shanwang Formation has not been investigated for cyclostratigraphy nor has it been dated with high precision methods. Now we use thorium data as a paleoenvironmental and paleoclimatic proxy to conduct a detailed cyclostratigraphic analysis. A new and simple cyclostratigraphic method, Wavelet Scale Series Analysis (WSSA) is developed to recognize Milankovitch cycles. A total of three short eccentricity and fifteen precession cycles are identified; obliquity cycles are not apparent. In the sedimentary succession, the corresponding precession and short eccentricity cycles are 1.17 m and 4.98 m thick respectively, with this verified by Correlation Coefficient (COCO) analysis and Multitaper-Method (MTM) spectral analysis. We estimate the studied interval was deposited over a duration of 0.3 Myr with a depositional rate of c. 5.7 cm/kyr. Paleomagnetic and radio isotope dating data shows that the diatomaceous shale was deposited during Chron C5En, which places it at approximately 18.5 Ma during the Burdigalian stage of the Early Miocene, rather than in the Middle Miocene as previously thought. The Shanwang lagerstätte biota therefore predates the Middle Miocene Climate Optimum (MMCO) and did not form within it. The geological time scale with a high resolution of 20 kyr was set accordingly.

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