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- 저자 : Xinping Yu (검색결과 4 건)
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Xiaohua Yu,Yaru Bi,Peng Chen,Xinping Liu 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.12
As the size of the city expands, longer journeys often involve the use of two or more modes of transportation. Feeder buses perform as a feeder mode of rail transit, its feeder areas are the key factor to improve this bus-rail transit mode service quality. Feeder areas that are either too small or too large can hinder the effectiveness of feeder buses. This paper presents a method to determine a suitable range as the key service of feeder buses for rail transit stations. The modal of accessibility consistency threshold interface of bus and bus-rail transit mode features is established, and the competition area of adjacent stations is considered to calculate the reasonable bus feeder range of rail transit stations. Based on the analysis of the demand characteristics of the feeder passengers, the potential passengers of the bus-rail transit travel mode are defined as the travel where only one endpoint of the starting and ending is within the walking range of the rail transit station, and a method for identifying the points of interest of potential passengers of the bus-rail transit mode is proposed. The potential passenger flow within the reasonable feeder range of rail transit stations is visualized, and the key service areas of feeder buses are determined based on the maximum potential passengers. Taking Jinan Metro Line NO.2 Stations as an example, combined with the station type, the key service area of feeder buses for railway stations is explained.
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Resonance analysis of cantilever porous graphene platelet reinforced pipe under external load
Qinghua Huang,Xinping Yu,Jun Lv,Jilie Zhou,Marischa Ray Elvenia 국제구조공학회 2022 Steel and Composite Structures, An International J Vol.45 No.3
Nowadays, there is a high demand for great structural implementation and multifunctionality with excellent mechanical properties. The porous structures reinforced by graphene platelets (GPLs) having valuable properties, such as heat resistance, lightweight, and excellent energy absorption, have been considerably used in different engineering implementations. However, stiffness of porous structures reduces significantly, due to the internal cavities, by adding GPLs into porous medium, effective mechanical properties of the porous structure considerably enhance. This paper is relating to vibration analysis of fluidconveying cantilever porous graphene platelet reinforced (GPLR) pipe with fractional viscoelastic model resting on foundations. A dynamical model of cantilever porous GPLR pipes conveying fluid and resting on a foundation is proposed, and the vibration, natural frequencies and primary resonant of such a system are explored. The pipe body is considered to be composed of GPLR viscoelastic polymeric pipe with porosity in which Halpin-Tsai scheme in conjunction with the fractional viscoelastic model is used to govern the construction relation of nanocomposite pipe. Three different porosity distributions through the pipe thickness are introduced. The harmonic concentrated force is also applied to the pipe and the excitation frequency is close to the first natural frequency. The governing equation for transverse motions of the pipe is derived by the Hamilton principle and then discretized by the Galerkin procedure. In order to obtain the frequency-response equation, the differential equation is solved with the assumption of small displacement, damping coefficient, and excitation amplitude by the multiple scale method. A parametric sensitivity analysis is carried out to reveal the influence of different parameters, such as nanocomposite pipe properties, fluid velocity and nonlinear viscoelastic foundation coefficients, on the primary resonance and linear natural frequency. Results indicate that the GPLs weight fraction porosity coefficient, fractional derivative order and the retardation time have substantial influences on the dynamic response of the system.
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Chongli Xu,Yu Liu,Yuchen Gong,Xinping Duan,Xiaochun Tang,Mingjun Zhang,Daxin Pang,Liqing Yu,Hongwei Zhao,Hongsheng Ouyang 한국유전학회 2015 Genes & Genomics Vol.37 No.2
Although Niemann-Pick C1-Like 1 (NPC1L1)plays a key role in intestinal cholesterol absorption, regulatingcholesterol metabolism and maintaining cholesterolmetabolic homeostasis, the molecular mechanism ofNPC1L1 in lipid-metabolism disorders leading to liverdisease remains largely unknown. Previous studies haveshown that NPC1L1 is related with the development offatty liver. Therefore, we hypothesized that NPC1L1 playsan important role in lipid-metabolism disorders and liverdisease by affecting the transcription of certain genesinvolved in lipid synthesis. To further elucidate the functionof NPC1L1, especially in the liver, we used somaticcellnuclear transfer to establish transgenic pigs thatexpressed human NPC1L1 in their livers. We investigatedsuperoxide dismutase activities and the levels of free fattyacids and malondialdehyde, a biomarker of lipid peroxidation. Superoxide dismutase activities significantlydecreased, and free fatty acid and malondialdehyde levelssignificantly increased in the NPC1L1 transgenic pigs,indicating that the overexpression of NPC1L1 in the liverresulted in severe lipid peroxidation. Our findings suggestthat NPC1L1 plays an important role in lipid-metabolismdisorders and liver disease.
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Su Tong,Zhang Zhe,Chen Yu,Wang Yun,Li Yumei,Xu Min,Wang Jian,Li Jing,Tian Xinping,Jin Zhengyu 대한영상의학회 2024 Korean Journal of Radiology Vol.25 No.4
Objective: To evaluate the image quality of novel dark-blood computed tomography angiography (CTA) imaging combined with deep learning reconstruction (DLR) compared to delayed-phase CTA images with hybrid iterative reconstruction (HIR), to visualize the cervical artery wall in patients with Takayasu arteritis (TAK). Materials and Methods: This prospective study continuously recruited 53 patients with TAK (mean age: 33.8 ± 10.2 years; 49 females) between January and July 2022 who underwent head-neck CTA scans. The arterial- and delayed-phase images were reconstructed using HIR and DLR. Subtracted images of the arterial-phase from the delayed-phase were then added to the original delayed-phase using a denoising filter to generate the final-dark-blood images. Qualitative image quality scores and quantitative parameters were obtained and compared among the three groups of images: Delayed-HIR, Dark-blood-HIR, and Dark-blood-DLR. Results: Compared to Delayed-HIR, Dark-blood-HIR images demonstrated higher qualitative scores in terms of vascular wall visualization and diagnostic confidence index (all P < 0.001). These qualitative scores further improved after applying DLR (Dark-blood-DLR compared to Dark-blood-HIR, all P < 0.001). Dark-blood DLR also showed higher scores for overall image noise than Dark-blood-HIR (P < 0.001). In the quantitative analysis, the contrast-to-noise ratio (CNR) values between the vessel wall and lumen for the bilateral common carotid arteries and brachiocephalic trunk were significantly higher on Darkblood- HIR images than on Delayed-HIR images (all P < 0.05). The CNR values were significantly higher for Dark-blood-DLR than for Dark-blood-HIR in all cervical arteries (all P < 0.001). Conclusion: Compared with Delayed-HIR CTA, the dark-blood method combined with DLR improved CTA image quality and enhanced visualization of the cervical artery wall in patients with TAK.
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