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Pseudorapidity Distributions of Charged Particles Produced in pp Collisions at the CERN LHC Energies
Jian-Xin Sun,Cai-Xing Tian,Er-Qin Wang,Fu-Hu Liu 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.5
The pseudorapidity distributions of charged particles produced in pp collisions at the CERN Large Hadron Collider (LHC) energies (0.9, 2.36, and 7 TeV) are studied by using the multisource thermal model. A group of extrapolated equations is used to determine various parameters. The calculated results are in agreement with the experimental data of the ALICE and CMS Collaborations at the LHC.
Two New Phenolic Compounds from the Fruiting Bodies of Ganoderma tropicum
Hu, Li-Li,Ma, Qing-Yun,Huang, Sheng-Zhuo,Guo, Zhi-Kai,Guo, Jian-Chun,Dai, Hao-Fu,Zhao, You-Xing Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.3
Chemical investigation of the fruiting bodies of Ganoderma tropicum led to the isolation of two new phenolic compounds, ganodermatropins A (1) and B (2). Their structures were elucidated by spectroscopic techniques (MS, 1D and 2D NMR). Ganodermatropin A exhibited antimicrobial activity against Staphylococcus aureus.
Jian He,Xulin Hu,Luyao Xing,Dongliang Chen,Lijun Peng,Gaofeng Liang,Chengdong Xiong,Xiangchun Zhang,Lifang Zhang 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.99 No.-
Tissue-engineered scaffolds acted as active natural extracellular matrices that allowed for cellattachment, migration, proliferation, and differentiation. To enhance the drug loading, degradationcontrol, and mechanical features of tissue-engineered scaffolds used in bone regeneration applications,we synthesized novel poly(trimethylene carbonate) (PTMC)/modified HA nanoparticles (KHA NPs,modified by silane coupling agent)/vancomycin hydrochloride (VH) porous microspheres scaffold. Thefabricated PTMC/KHA/VH scaffold has unique surface corrosion degradation, excellent surface properties,and high cytocompatibility. The novel PTMC/KHA/VH scaffold was characterized by 42% porosity,100 mmpore size, and 208.2 MPa compressive modulus. After the treatment of a rat femur defect for 4, 8, and 12weeks, the surface corrosion biodegraded of the PTMC/KHA/VH scaffold remarkably decreasedinflammation response and promoted bone regeneration, suggesting its use as a bioactive structurein bone tissue engineering.
Meng-Yuan Hu,Kuan-Kuan Xiong,Jian-Rong Li,Xing-Bin Jing,Pei-Hua Zhao 한국섬유공학회 2019 Fibers and polymers Vol.20 No.9
A new P/N/Si/S-containing mononickel complex NiS, which can be regarded as a rare type of the metal-basedintumescent flame retardant, has been prepared through the condensation reaction of precursor NiCl with 1, 2-ethanedithiolin the presence of triethylamine as acid-binding agent. Its molecular structure is well characterized by elemental analysis,infrared (IR) and nuclear magnetic resonance (NMR) spectroscopies. The target flame retardant NiS has been successfullyapplied to cotton fabrics through a pad-dry-cure method. Thermal degradation properties of neat and treated cotton fabricswith 10.7 wt% NiS are studied by thermogravimetric analysis (TGA). Flammability behaviors of neat and treated cotton with10.7 wt% NiS are evaluated using vertical burning test, limiting oxygen index (LOI) and microscale combustion calorimeter(MCC). Meanwhile, to further investigate the flame retardancy of NiS for cotton fabrics, the char layers of neat and treatedsamples after combustion are analyzed by SEM image and Raman spectroscopy. As a result, the improved thermal andflammability performance for cotton fabrics by introduction of NiS might be due to the metal-assisted catalytic charringeffect of NiS on the formation of the compact char layer and the release of the flammable gas.
Branched polymeric prodrug/programmed cell death 4 complexes for combinational cancer therapy
Yu‑Jing He,Lei Xing,Peng‑Fei Cui,Jia‑Liang Zhang,Jian‑Bin Qiao,Cheng‑Qiong Luo,Ge Jiang,Hu‑Lin Jiang 한국약제학회 2017 Journal of Pharmaceutical Investigation Vol.47 No.2
Here, we demonstrate a co-delivery system constructed by integrating chemotherapeutic molecules into branched polymeric prodrug which can condense nucleic acids. Demethylcantharidate (DCA) was chosen as a model drug and premodified through nucleophilic substitution reaction by its two carboxylic groups with allyl chloride. The synthesized intermediate (DCA-dially) was then used to polymerize with tris (2-aminoethyl) amine (TAEA) through progressively ammonolysis reaction. The obtained poly (DCA-alt-TAEA) (DCAT) was used to pack PDCD4 into spherical-like nanoparticles through electrostatic interaction. Gel retardation assays implied that DCAT could integrate DNA at the weight ratio of 1 and protect it from digestion by nuclease. Acid-base titration experiments showed that DCAT obtained preferable buffering capability which was beneficial for the endosomal escape of DCAT/PDCD4 complexes. Cellular tests involving gene transfection efficiency and cytotoxicity indicated that DCA and PDCD4 co-delivered by the complexes significantly and synergistically suppressed the viability of SMMC-7721 cells. These results suggest that integrating chemotherapeutic molecules into nucleic acid-packing polymeric prodrug as cationic polymer/PDCD4 complexes is a highly efficient way to co-deliver chemotherapeutic drugs and nucleic acids for cancer therapy.
An analytical solution of bending thin plates with different moduli in tension and compression
He, Xiao-Ting,Hu, Xing-Jian,Sun, Jun-Yi,Zheng, Zhou-Lian Techno-Press 2010 Structural Engineering and Mechanics, An Int'l Jou Vol.36 No.3
Materials which exhibit different elastic moduli in tension and compression are known as bimodular materials. The bimodular materials model, which is founded on the criterion of positive-negative signs of principal stress, is important for the structural analysis and design. However, due to the inherent complexity of the constitutive relation, it is difficult to obtain an analytical solution of a bimodular bending components except in particular simple problems. Based on the existent simplified model, this paper solves analytically bending thin plates with different moduli in tension and compression. By using the continuity conditions of stress components in unknown neutral layer, we determine the location of the neutral layer, and derive the governing differential equation for deflection, the flexural rigidity, and the internal forces in the thin plate. We also use a circular thin plate with bimodulus to illustrate the application of this solution derived in this paper. The results show that the introduction of different moduli has influences on the flexural stiffness of the bending thin plate.
Experimental study of TiO2 hollow microspheres removal on elemental mercury in simulated flue gas
Jiang Wu,Xian Li,Jian-Xing Ren,Xuemei Qi,Ping He,Bu Ni,Chong Zhang,Chengzhen Hu,Jun Zhou 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.32 No.-
TiO2 hollow sphere was synthesized by hydrothermal method using trifluoroacetic acid (TFA) andTi(SO4)2 as raw materials, and it was applied to photocatalytic oxidization of elemental mercury (Hg0) inthe simulated flue gas. The prepared samples were well characterized by X-ray diffraction (XRD),scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectronspectroscopy (XPS), UV–vis diffuse reflectance spectra (UV-vis DRS) and nitrogen adsorption/desorption. The results showed that only anatase phase TiO2 hollow sphere was obtained. The average diameter ofTiO2 hollow spheres was about 800 nm and the shell thickness was about 200–400 nm. When M, themolar ratio of TFA to Ti(SO4)2, was higher than a certain value, the photocatalytic activity of preparedTiO2 hollow spheres began to reduce. When M = 2, addition TFA content was the best quantity, which gotthe best TiO2 hollow spheres and provided the most appropriate F decomposed from TFA during thesample preparation, which was helpful to its photocatalytic ability. In the experimental temperaturerange, the photocatalytic oxidation efficiency decreased with the increasing of reaction temperature, andthe intensity of UV irradiation had an important effect on the photocatalytic reaction. When UVirradiation intensity was 303.45 mW cm 2 and reaction temperature was 55 8C, TiO2 hollow spheresample prepared at M = 2 had the highest photocatalytic ability and the mercury removal efficiencyreached up to 82.75%.
Chen, Si-Ying,Hu, Sa-Sa,Dong, Qian,Cai, Jiang-Xia,Zhang, Wei-Peng,Sun, Jin-Yao,Wang, Tao-Tao,Xie, Jiao,He, Hai-Rong,Xing, Jian-Feng,Lu, Jun,Dong, Ya-Lin Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10
Background: Breast cancer is a common malignant tumor which affects health of women and multidrug resistance (MDR) is one of the main factors leading to failure of chemotherapy. This study was conducted to establish paclitaxel-resistant breast cancer cell line and nude mice models to explore underlying mechanisms of MDR. Methods: The breast cancer drug-sensitive cell line MCF-7 (MCF-7/S) was exposed in stepwise escalating paclitaxel (TAX) to induce a resistant cell line MCF-7/TAX. Cell sensitivity to drugs and growth curves were measured by MTT assay. Changes of cell morphology and ultrastructure were examined by optical and electron microscopy. The cell cycle distribution was determined by flow cytometry. Furthermore, expression of proteins related to breast cancer occurrence and MDR was tested by immunocytochemistry. In Vivo, nude mice were injected with MCF-7/S and MCF-7/TAX cells and weights and tumor sizes were observed after paclitaxel treatment. In addition, proteins involved breast cancer and MDR were detected by immunohistochemistry. Results: Compared to MCF-7/S, MCF-7/TAX cells had a higher resistance to paclitaxel, cross-resistance and prolonged doubling time. Moreover, MCF-7/TAX showed obvious alterations of ultrastructure. Estrogen receptor (ER) expression was low in drug resistant cells and tumors while expression of human epidermal growth factor receptor 2 (HER2) and Ki-67 was up-regulated. P-glycoprotein (P-gp), lung resistance-related protein (LRP) and glutathione-S-transferase-${\pi}$ (GST-${\pi}$) involved in the MDR phenotype of resistant cells and tumors were all overexpressed. Conclusion: The underlying MDR mechanism of breast cancer may involve increased expression of P-gp, LRP and GST-${\pi}$.
An analytical solution of bending thin plates with different moduli in tension and compression
Xiao-ting He,Xing-jian Hu,Jun-yi Sun,Zhou-lian Zheng 국제구조공학회 2010 Structural Engineering and Mechanics, An Int'l Jou Vol.36 No.3
Materials which exhibit different elastic moduli in tension and compression are known as bimodular materials. The bimodular materials model, which is founded on the criterion of positivenegative signs of principal stress, is important for the structural analysis and design. However, due to the inherent complexity of the constitutive relation, it is difficult to obtain an analytical solution of a bimodular bending components except in particular simple problems. Based on the existent simplified model, this paper solves analytically bending thin plates with different moduli in tension and compression. By using the continuity conditions of stress components in unknown neutral layer, we determine the location of the neutral layer, and derive the governing differential equation for deflection, the flexural rigidity, and the internal forces in the thin plate. We also use a circular thin plate with bimodulus to illustrate the application of this solution derived in this paper. The results show that the introduction of different moduli has influences on the flexural stiffness of the bending thin plate.