Mining Frequent Sub-hypergraph in an Uncertain Hypergraph for Knowledge Transfer

Xing Wang,Bin-Xing Fang,Hui He,Hong-Li Zhang 보안공학연구지원센터 2015 International Journal of Database Theory and Appli Vol.8 No.4

The knowledge transfer learning can generalize across domains where the types of objects and variables are different. Previous studies ignored connectivity and creativity of domain knowledge. Thus, these studies just transfer knowledge from a source domain to a target domain that not effectively use the knowledge from other domains. We proposed a method, called Multi-domain second order knowledge integration (MSKI), for integrating to address this problem. We hybridize and create new knowledge, which is formalized into an uncertain hypergraph. Then, we proposed a method to mine frequent sub-hypergraph from the uncertain hypergraph (MFS-UHG). The frequent sub-hypergraphs are pivot knowledge, which has to be transferred with high priority. We embed the pivot knowledge in the progress of MLN structure learning. The experimental evaluation on four domain datasets shows that the MSKI outperforms state-of-the-art MLN-based transfer learning.

티타늄 표면처리가 골모세포의 반응에 미치는 영향

( Xing Hui Piao ),김영준 조선대학교 치의학연구원 2015 Oral Biology Research (Oral Biol Res) Vol.39 No.2

Purpose: This study was carried out to evaluate the effects of several surface modifications with titanium on cell responses. Materials and Methods: Titanium discs (15 mm in diameter and 2 mm in thickness) were divided into five groups; control group, acid-treated group, alkali-heat-treated group, sandblasting with large grit and acid etching group, and resorbable blasted media group. The control group had a non-treated machined titanium surface. Changes in surface morphology were observed by scanning electron microscope (SEM) and atomic force microscope, substances were analyzed by X-ray diffraction, and hydrophilic properties and surface tension were measured by the contact angle test. In order to examine biological responses, SEM observation, 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, and measurement of alkaline phosphatase (ALP) activity were carried out. Results: The results are as follows. Each group showed a different surface morphology. Roughness test showed a statistically significant difference in Ra values. In the SEM analysis, spindle shaped cells with well-developed projections were detected, and cells were well attached. The alkali-heat-treated group showed the greatest number of attached cells, which had connecting projections. In the MTT analysis, the alkali-heat-treated group showed better cell viability than the other groups. Control and alkali-heat-treated groups showed similar cell viabilities. In the ALP activity test, every surface-treated group showed significantly higher values than the control group. Especially, alkali-heat-treated group had the highest ALP activity. Conclusion: The results suggest that titanium surface modification could show better surface properties and biological characteristics, especially in the alkali-heat-treated surface.

Applying the OMOP Common Data Model to Facilitate Benefit-Risk Assessments of Medicinal Products Using Real-World Data from Singapore and South Korea

Hui Xing Tan,Desmond Chun Hwee Teo,이동윤,김청수,Jing Wei Neo,Cynthia Sung,Haroun Chahed,Pei San Ang,Doreen Su Yin Tan,박래웅,Sreemanee Raaj Dorajoo 대한의료정보학회 2022 Healthcare Informatics Research Vol.28 No.2

Objectives: The aim of this study was to characterize the benefits of converting Electronic Medical Records (EMRs) to acommon data model (CDM) and to assess the potential of CDM-converted data to rapidly generate insights for benefitriskassessments in post-market regulatory evaluation and decisions. Methods: EMRs from January 2013 to December 2016were mapped onto the Observational Medical Outcomes Partnership-CDM (OMOP-CDM) schema. Vocabulary mappingswere applied to convert source data values into OMOP-CDM-endorsed terminologies. Existing analytic codes used in a priorOMOP-CDM drug utilization study were modified to conduct an illustrative analysis of oral anticoagulants used for atrialfibrillation in Singapore and South Korea, resembling a typical benefit-risk assessment. A novel visualization is proposed torepresent the comparative effectiveness, safety and utilization of the drugs. Results: Over 90% of records were mapped ontothe OMOP-CDM. The CDM data structures and analytic code templates simplified the querying of data for the analysis. Intotal, 2,419 patients from Singapore and South Korea fulfilled the study criteria, the majority of whom were warfarin users. After 3 months of follow-up, differences in cumulative incidence of bleeding and thromboembolic events were observable viathe proposed visualization, surfacing insights as to the agent of preference in a given clinical setting, which may meaningfullyinform regulatory decision-making. Conclusions: While the structure of the OMOP-CDM and its accessory tools facilitatereal-world data analysis, extending them to fulfil regulatory analytic purposes in the post-market setting, such as benefit-riskassessments, may require layering on additional analytic tools and visualization techniques.

Ago2 and GW182 Expression in Preimplantation Mouse Embryos: A Link of MicroRNA Biogenesis and GW182 Protein Synthesis

Xing-Hui Shen,Young-Joon Han,Byoung-Chul Yang,Xiang-Shun Cui,Nam-Hyung Kim 한국동물생명공학회(구 한국동물번식학회) 2009 Reproductive & developmental biology Vol.33 No.2

A high-efficiency simulation method of wind field and its application on transmission line

Xing Fu,Xing-Heng Zhang,Hong-Nan Li,Gang Li,Hui-Juan Liu 한국풍공학회 2021 Wind and Structures, An International Journal (WAS Vol.33 No.4

Generally, the fluctuating wind is simplified as several independent one-dimensional multivariate stationary Gaussian processes in simulating a natural wind field. The correlation in the lateral, longitudinal and vertical directions should all be considered in the simulation of longitudinal wind field for the large-span spatial structures. In fact, this type of structure has lots of simulation points. The calculation amount of wind field simulation by the harmonic superposition method depends on the scale of cross-spectral density matrix, which is directly related to the number of simulated points, leading to a low efficiency when generating the time-varying wind speed. This paper innovatively proposes a high-efficiency simulation method for the longitudinal wind field based on Taylor’s hypothesis. Subsequently, the effectiveness of the proposed wind field method was verified by the numerical simulation. Finally, the dynamic responses of a transmission tower-line system under the wind loadings generated with the new method and traditional method are calculated and compared. The percentages difference of the mean and maximum axial force at the main tower members are less than 0.02% and 1%, respectively, indicating the effectiveness of the proposed time delay method. The results also show that the proposed simulation method of wind field can not only ensure the simulation accuracy, but also significantly improve the efficiency of wind speed generation, which is suitable for the wind load simulation of large-span spatial structures.

A Dependence Stability Bound based on the VC Dimension for Relational Classification

Xing Wang,Hui He,Bin-Xing Fang,Hong-Li Zhang 보안공학연구지원센터 2015 International Journal of Database Theory and Appli Vol.8 No.3

Relational classification (RC) is concerned with the application of statistical learning to relational data. RC models do not have improved stability to smooth the perturbations generated by variations in the correlation between the relational data. Therefore, few studies have attempted to derive a bound and develop a stability learning framework for RC models. To solve this problem, we derive a learning bound with a new measure dependence stability and a limited Vapnik–Chervonenkis (VC) dimension. Based on the learning bound, we then design a stable learning framework that serves as a guideline for the development of new learning algorithms for a broad class of RC models. Applying a Markov logic network on synthesized and real-world datasets, our experimental results demonstrate that our bound can be tight if the RC model has appropriate dependence stability and limited VC dimension and our learning framework increases the stability of RC models while reducing the deviation between empirical risk and true risk.

Density Functional Study on [3+2]-Dipolar Cycloaddition Reaction of the N-heterocyclic Carbene Boryl Azide with Olefins

Xing-hui Zhang,Ke-tai Wang,Teng Niu,Shan-shan Li 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.5

The cycloaddition reactions of the N-heterocyclic carbene boryl azide with methyl acrylate, butenone, and hexafluoropropene have been investigated theoretically. Solvent effects on these reactions have been explored by calculation that included a polarizable continuum model (PCM) for the solvent (C6H6). The title reaction could produce 4- and 5-substituted 1,2,3-triazolines, respectively. The reaction systems have the higher chemical reactivity with the low barriers and could be favored. Yet the smaller differences have been found to occur in energetics, and the cycloaddition reactions occur for s-trans conformations over s-cis conformations. The calculations indicated that the cycloaddition reaction of the alkenes have certain regioselectivity.

DFT Studies on Two Novel Explosives Based on the Guanidine-Fused Bicyclic Structure

Xing-Hui Ji,Bing-Cheng Hu,Huan-Qing Jia,Zu Liang Liu,Chun-Xu Lu 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.4

Density functional theory (DFT) calculations at the B3LYP/6-31G(d,p) theoretical level were performed for two novel explosives (compounds B and C) based on the guanidine-fused bicyclic skeleton C4N6H8 (A). The heats of formation (HOFs) were calculated via isodesmic reaction. The detonation properties were evaluated by using the Kamlet-Jacobs equations. The bond dissociation energies (BDEs) for the thermolysis initiation bond were also analyzed to investigate the thermal stability. The results show that the compounds have high positive HOF values (B, 1064.68 kJ·mol−1; C, 724.02 kJ·mol−1), high detonation properties (ρ, D and P values of 2.04 g·cm−3 and 2.21 g·cm−3, 9.98 km·s−1 and 10.99 km·s−1, 46.44 GPa and 59.91 Gpa, respectively) and meet the basic stability requirement. Additionally, feasible synthetic routes of the these high energy density compounds (HEDCs) were also proposed via retrosynthetic analysis.

Microstructure Evolution of Inconel 718 Alloy during Ring Rolling Process

Xing-lin Zhu,Dong Liu,Li-juan Xing,Yang Hu,Yan-hui Yang 한국정밀공학회 2016 International Journal of Precision Engineering and Vol.17 No.6

Microstructure determines the comprehensive mechanical properties and service life of ring parts. In this study, ring rolling process is considered as a multi-pass process which is parted into four phases, and the microstructure evolution model is then established based on the characteristics of this multi-pass process by combining with a 3D coupled thermo-mechanical FE model. By contrasting with experiment results, the microstructure evolution model is actually proven can be competently applied to predict the microstructure of the formed ring. Also through comprehensive analysis on distribution of recrystallization fractions based on the microstructure evolution model, conclusions can be summarized as following. (1) It is inaccurate to predict the microstructure by regarding the ring rolling as a single-pass deformation. The ring rolling process should be parted into different phases, and for each phase, the singlepass microstructure evolution model is adapted. (2) Different with single-pass deformation, due to the high temperature dwelling phase during ring rolling process, meta-dynamic recrystallization (MDR) is another important grain refinement mechanism besides dynamic recrystallization (DR). (3) MDR has different distribution trends with DR, which is benefit not only for grains refinement but also for microstructure uniformity. (4) Rolling penetration is obviously improved with feed rate increases, whereas, unduly high feed rate leads to recrystallization fraction decrease in outer layer area, which is adverse to microstructure uniformity.

Gingival and bone healing patterns with ridge preservation in beagle dogs

Xing-Hui Piao,Hyo-Seon Park,Eui-Ri Na,Young-Joon Kim,Jong-Wook Moon 조선대학교 치의학연구원 2020 Oral Biology Research (Oral Biol Res) Vol.44 No.2

The aim of this study was to evaluate the clinical and histologic findings of bone and gingival healing patterns with ridge preservation. The mandibular third premolars were extracted from beagle dogs and the dogs were euthanized after 12 weeks. The ridge preservation was performed and the animals were divided into 3 groups, including 1) Control: extraction; 2) surederm group: extraction+acellular dermal matrix (Surederm); 3) collatape group: extraction+collagen membrane (Collatape). Changes in the keratinized gingiva and bone volume of the extraction sockets were measured. In the surederm and collatape group, the decrease in keratinization was small and statistically insignificant. The surederm group had significantly greater dimensions of buccal gingiva as compared to the control and collatape groups at 4 weeks. The surederm group had greater dimensions of buccal gingiva as compared to the control group at 8 weeks. Histological observation showed that in the surederm group, a dark red-colored osteoid seam was observed around the alveolar bone. Osteoid seams were observed directly below and to the side of the socket. In the collatape group, a connective tissue band was observed at the site of contact with the alveolar bone. Both experimental groups had more alveolar bone volume than the control. The alveolar bone volume in the surederm group was significantly greater than that of the collatape group. The results suggest that the acellular dermal matrix results in better healing patterns than other methods.