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      • KCI등재

        Experimental Study on Interfacial Shear Performance of RC Beams Added to Existing RC Columns

        Xin-Ling Wang,Lei-Lei Jin,Ke Li,Jun-Tao Zhu 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.11

        The primary objectives of this study were to experimentally investigate the shear characteristicsof the interface between an existing RC column and a reinforced concrete (RC) beam added to the existing RC column, and to propose a formula for estimating the shear capacity of the beam-column interface. The major test variables consisted of concrete strength, added steel reinforcement ratio and shear span to depth ratio. Failure characteristics, displacements at the loading point, slips of the beam-column interface, and shear capacities of the beam-column interface were analyzed. Test results indicate that both the shear capacity of the beam-column interface and the corresponding interfacial slip increased with a decrease in shear span to depth ratio. In addition, as concrete strength grew, the shear capacity of the beam-column interface increased, but the interfacial slip corresponding to the interfacial shear capacity remained almost unchanged. Moreover, both the shear capacity of the beam-column interface and the corresponding interfacial slip increased with an increase in the longitudinal steel reinforcement ratio of the added RC beam. A formula for predicting the shear capacity of the beam-column interface was developed. The test results validate the proposed formula and provide important guidance for the design of the RC beam added to the existing RC column.

      • KCI등재

        A Novel Intermediate Estimator Based Secure Consensus Control for Multi-agent Systems with Application to Networked Multi-axis Motion Synchronization

        Jun-Wei Zhu,Chao-Yang Liang,De-Feng He,Xin Wang 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.4

        This paper studies the secure consensus control problem of multi-agent systems under DoS attacks onthe sensor, the actuator, and the communication topology. A resilient intermediate estimator based attack tolerantcontrol strategy is proposed. By fully exploiting the hardware redundancies, both of the estimators and the controlprotocols can be reconstructed online according to different DoS attack scenarios. Finally, the experiment results ofthe networked multi-axis motion control system are given to verify the effectiveness of the proposed method.

      • KCI등재

        Effects of rehydration on physiological and transcriptional responses of a water-stressed rhizobium

        Zhu Jie,Jiang Xin,Guan Dawei,Kang Yaowei,Li Li,Cao Fengming,Zhao Baisuo,Ma Mingchao,Zhao Ji,Li Jun 한국미생물학회 2022 The journal of microbiology Vol.60 No.1

        As a microsymbiont of soybean, Bradyrhizobium japonicum plays an important role in symbiotic nitrogen fixation and sustainable agriculture. However, the survival of B. japonicum cells under water-deplete (e.g., drought) and water-replete (e.g., flood) conditions is a major concern affecting their nitrogen-fixing ability by establishing the symbiotic relationship with the host. In this study, we isolated a water stress tolerant rhizobium from soybean root nodules and tested its survival under water-deplete conditions. The rhizobium was identified as Bradyrhizobium japonicum and named strain 5038. Interestingly, both plate counting and live/dead fluorescence staining assays indicate that a number of viable but non-culturable cells exist in the culture medium upon the rehydration process which could cause dilution stress. Bradyrhizobium japonicum 5038 cells increased production of exopolysaccharide (EPS) and trehalose when dehydrated, suggesting that protective responses were stimulated. As expected, cells reduced their production upon the subsequent rehydration. To examine differential gene expression of B. japonicum 5038 when exposed to water-deplete and subsequent waterreplete conditions, whole-genome transcriptional analysis was performed under 10% relative humidity (RH), and subsequent 100% RH, respectively. A total of 462 differentially expressed genes (DEGs, > 2.0-fold) were identified under the 10% RH condition, while 3,776 genes showed differential expression during the subsequent rehydration (100% RH) process. Genes involved in signal transduction, inorganic ion transport, energy production and metabolisms of carbohydrates, amino acids, and lipids were far more up-regulated than downregulated in the 10% RH condition. Notably, trehalose biosynthetic genes (otsAB, treS, and treYZ), genes ligD, oprB, and a sigma factor rpoH were significantly induced by 10% RH. Under the subsequent 100% RH condition, genes involved in transcription, translation, cell membrane regulation, replication and repair, and protein processing were highly up-regulated. Interestingly, most of 10%-RH inducible genes displayed rehydration-repressed, except three genes encoding heat shock (Hsp20) proteins. Therefore, this study provides molecular evidence for the switch of gene expression of B. japonicum cells when encountered the opposite water availability from water-deplete to water-replete conditions.

      • Safety Assessment of Ovarian Cryopreservation and Transplantation in Nude Mice Bearing Human Epithelial Ovarian Cancer

        Zhu, Gen-Hai,Wang, Sheng-Tan,Yang, Zhao-Xin,Cai, Jun-Hong,Chen, Chun-Ying,Yao, Mao-Zhong,Hong, Lan,He, Guo-Li,Yang, Shu-Ying Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9

        Objective: Nude mice with orthotopic transplantation of human ovarian epithelial cancer were used to investigate screening criteria for paraneoplastic normal ovarian tissue and the security of the freezing and thawing for ovarian tissue transplantation. Methods: Expression of CK-7, CA125, P53, survivin, MMP-2/TIMP-2 in paraneoplastic normal ovarian tissues were detected by RT-PCR as well as immunohistochemistry. The tissues of the groups with all negative indicators of RT-PCR, all negative indicators of immunohistochemistry, negative expression of CK-7, CA125 and survivin, positive expression of CK-7, CA125 and survivin, cancer tissues and normal ovarian tissues of nude mice were used for freezing and thawing transplantation, to analyze overt and occult carcinogenesis rates after transplantation. Results: When all indicators or the main indicators, CK-7, CA125 and survivin, were negative, tumorigenesis did not occur after transplantation. In addition the occult carcinogenesis rate was lower than in the group with positive expression of CK-7, CA125 and survivin (P<0.01). After subcutaneous and orthotopic transplantation of ovarian tissues, rates did not change (P>0.05). There was no statistical significance among rates after transplantation of ovarian tissues which were obtained under different severity conditions (P>0.05). Conclusion: Negative expression of CK-7, CA125 and survivin can be treated as screening criteria for security of ovarian tissues for transplantation. Immunohistochemical methods can be used as the primary detection approach. Both subcutaneous and orthotopic transplantation are safe. The initial severity does not affect the carcinogenesis rate after tissue transplantation. Freezing and thawing ovarian tissue transplantation in nude mice with human epithelial ovarian carcinoma is feasible and safe.

      • KCI등재

        A Model Transfer Learning Based Fault Diagnosis Method for Chemical Processes With Small Samples

        Jun-Wei Zhu,Bo Wang,Xin Wang 제어·로봇·시스템학회 2023 International Journal of Control, Automation, and Vol.21 No.12

        Traditional fault diagnosis methods relies on sufficient fault samples, but it is unrealistic since the fault is a low possibility event in real industrial scenes. To address the above issue, this paper proposed a fault diagnosis method for chemical processes with small samples. First, a data self-generating-based transfer learning (DSGTL) method is presented to expand the fault samples. The characteristic of fault data is learned by adversarial relation and transferred to the generated data. Moreover, a model-based transfer learning strategy is adopted to improve the robustness of the proposed method to the quality of generated data. Second, the sample reconstruction-based convolutional neural network (SR-CNN) is proposed which adaptively extracts features from both spatial domain and time domain and identifies the fault type of industrial process with small samples. Finally, the experimental result of the Tennessee Eastman (TE) process proves the validity and the feasibility of the proposed method.

      • KCI등재

        Association between the severity of hypodontia and the characteristics of craniofacial morphology in a Chinese population: A cross-sectional study

        Xin Xiong,Jiaqi Liu,Yange Wu,Chengxinyue Ye,Qinlanhui Zhang,Yufan Zhu,Wenke Yang,Jun Wang 대한치과교정학회 2023 대한치과교정학회지 Vol.53 No.3

        Objective: To investigate craniofacial differences in individuals with hypodontia and explore the relationship between craniofacial features and the number of congenitally missing teeth. Methods: A cross-sectional study was conducted among 261 Chinese patients (males, 124; females, 137; age, 7–24 years), divided into four groups (without hypodontia: no teeth missing, mild: one or two missing teeth, moderate: three to five missing teeth, severe: six or more missing teeth) according to the number of congenitally missing teeth. Differences in cephalometric measurements among the groups were analyzed. Further, multivariate linear regression and smooth curve fitting were performed to evaluate the relationship between the number of congenitally missing teeth and the cephalometric measurements. Results: In patients with hypodontia, SNA, NA-AP, FH-NA, ANB, Wits, ANS-Me/N-Me, GoGn-SN, UL-EP, and LL-EP significantly decreased, while Pog-NB, AB-NP, N-ANS, and S-Go/N-Me significantly increased. In multivariate linear regression analysis, SNB, Pog-NB, and S-Go/N-Me were positively related to the number of congenitally missing teeth. In contrast, NA-AP, FH-NA, ANB, Wits, N-Me, ANS-Me, ANS-Me/N-Me, GoGn-SN, SGn-FH (Y-axis), UL-EP, and LL-EP were negatively related, with absolute values of regression coefficients ranging from 0.147 to 0.357. Further, NA-AP, Pog-NB, S-Go/N-Me, and GoGn-SN showed the same tendency in both sexes, whereas UL-EP and LL-EP were different. Conclusions: Compared with controls, patients with hypodontia tend toward a Class III skeletal relationship, reduced lower anterior face height, flatter mandibular plane, and more retrusive lips. The number of congenitally missing teeth had a greater effect on certain characteristics of craniofacial morphology in males than in females.

      • SCIESCOPUSKCI등재

        Review : Recovery Processes of Organic Acids from Fermentation Broths in the Biomass-Based Industry

        ( Qian Zhu Li ),( Xing Lin Jiang ),( Xin Jun Feng ),( Ji Ming Wang ),( Chao Sun ),( Hai Bo Zhang ),( Mo Xian ),( Hui Zhou Liu ) 한국미생물 · 생명공학회 2016 Journal of microbiology and biotechnology Vol.26 No.1

        The new movement towards green chemistry and renewable feedstocks makes microbial production of chemicals more competitive. Among the numerous chemicals, organic acids are more attractive targets for process development efforts in the renewable-based biorefinery industry. However, most of the production costs in microbial processes are higher than that in chemical processes, among which over 60% are generated by separation processes. Therefore, the research of separation and purification processes is important for a promising biorefinery industry. This review highlights the progress of recovery processes in the separation and purification of organic acids, including their advantages and disadvantages, current situation, and future prospects in terms of recovery yields and industrial application.

      • Survivin Gene Functions and Relationships between Expression and Prognosis in Patients with Nasopharyngeal Carcinoma

        Cai, Jun-Hong,Fu, Sheng-Miao,Tu, Zhi-Hua,Deng, Li-Qun,Liang, Zhu,Chen, Xin-Ping,Gong, Xuan-Ju,Wan, Li-Hua Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.6

        This study aimed to investigate the relationship between prognosis and protein and mRNA expression of an apoptotic inhibitor gene, survivin, in patients with nasopharyngeal carcinoma. Furthermore, functions of the survivin gene in the CNE2 nasopharyngeal carcinoma cell line were assessed. Immunohistochemistry and in situ hybridization were used in detecting the survivin protein and mRNA in 44 nasopharyngeal carcinoma specimens, and 30 chronic nasopharyngitis samples as controls. Survivin gene expression in CNE2 cell line was suppressed with an shRNA (short hairpin RNA). The positive ratios of expression for survivin protein and mRNA in nasopharyngeal carcinoma were 79.5% and 75.0% respectively, obviously higher than in the control group (p<0.01), and there is very good consistency between the two methods. The mean survival time of patients with higher survivin protein or mRNA expression was shorter than in patients with lower levelsv(p<0.01). Proliferation of the CNE2 cell line was distinctly inhibited by the shRNA. The results indicate that overexpression of the survivin gene plays an important role in onset and development of nasopharyngeal carcinoma, and it may be helpful for prognostic appraisal.

      • KCI등재

        Electronic Structure, Phase Transition, and Elastic Properties of ScC under High Pressure

        Yu-Xin Zhao,Jun Zhu,Yan-Jun Hao,Zi-Yuan Li,Long-Qing Chen,Guang-Fu Ji 한국물리학회 2015 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.67 No.12

        The structural properties and the phase transition for scandium carbide (ScC) have been studied in NaCl (B1), CsCl (B2), ZB (B3), WZ (B4), NiAs (B81), WC (Bh), and Pmmn structures by using the pseudopotential plane-wave method in the framework of the density functional theory. Our theoretical results show that the most stable structure is the B1 phase, contrary to the result of Rahim et al. The phase transitions B1 ! Pmmn and Pmmn ! B2 are predicted at 83.7 and 109.7 GPa, respectively. At the same time, we find that the B3, B4, B81, and Bh phases are not stable over the whole pressure range considered. In particular, the elastic constants of Pmmn-ScC under high pressure are obtained successfully. The effects of pressure on the elastic properties of B1-ScC and Pmmn-ScC are also predicted. The Debye temperatures and the sound velocities of these two structures are estimated from the elastic constants, and by analyzing G/B, the brittle-ductile behavior of ScC is assessed. In addition, the density of states of B1-ScC at high pressures is also discussed.

      • KCI등재

        Polarization Error Analysis of an All-Optical Fibre Small Current Sensor for Partial Discharge

        Gaifang Xin,Jun Zhu,Chengming Luo,Jing Tang,Wei Li,Yuxin Cao,Haiyan Xu 대한전기학회 2020 Journal of Electrical Engineering & Technology Vol.15 No.5

        In view of the characteristics of the small amplitude of a current signal, an all-optical fi bre small-current sensor for partial discharge is devised. A novel type of sensor head with electric winding light is proposed. A complete optical model of the optical fi bre current sensor is developed under the eff ect of polarization error factors. In addition, the eff ect of polarization error factors on the optical fi bre sensing system is simulated. The simulation results show that as the extinction ratio increases, the output relative error of the optical fi bre small-current sensor decreases. The eff ect of the fast and slow axis misalignment errors of a polarizing beam splitter is similar to the eff ect of the alignment angle error of an optical fi bre polarizer. It is observed that the relative error curve follows a sine function. Meanwhile, the output relative error increases fi rst and then oscillates with an increase in the linear birefringence. We conclude that the linear birefringence of the sensing optical fi bre is the main error source for the measurement accuracy of the sensing system. Finally, an experimental system for the optical fi bre small-current sensor is implemented. The experimental results show that the eff ect of linear birefringence on the fi bre current sensing system can be suppressed by introducing a large amount of circular birefringence into the sensing optical fi bre. The theoretical mechanism of these errors is analysed, which can be applied to implement corresponding measures to reduce the eff ect of error factors on the sensing system and further improve the measurement accuracy of the optical fi bre small-current sensor.

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