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      • KCI등재

        Noncontrast Computed Tomography-Based Radiomics Analysis in Discriminating Early Hematoma Expansion after Spontaneous Intracerebral Hemorrhage

        Song Zuhua,Guo Dajing,Tang Zhuoyue,Liu Huan,Li Xin,Luo Sha,Yao Xueying,Song Wenlong,Song Junjie,Zhou Zhiming 대한영상의학회 2021 Korean Journal of Radiology Vol.22 No.3

        Objective: To determine whether noncontrast computed tomography (NCCT) models based on multivariable, radiomics features, and machine learning (ML) algorithms could further improve the discrimination of early hematoma expansion (HE) in patients with spontaneous intracerebral hemorrhage (sICH). Materials and Methods: We retrospectively reviewed 261 patients with sICH who underwent initialNCCT within 6 hours of ictus and follow-up CT within 24 hours after initial NCCT, between April 2011 and March 2019. The clinical characteristics, imaging signs and radiomics features extracted from the initial NCCT images were used to construct models to discriminate early HE. A clinical-radiologic model was constructed using a multivariate logistic regression (LR) analysis. Radiomics models, a radiomics-radiologic model, and a combined model were constructed in the training cohort (n = 182) and independently verified in the validation cohort (n = 79). Receiver operating characteristic analysis and the area under the curve (AUC) were used to evaluate the discriminative power. Results: The AUC of the clinical-radiologic model for discriminating early HE was 0.766. The AUCs of the radiomics model for discriminating early HE built using the LR algorithm in the training and validation cohorts were 0.926 and 0.850, respectively. The AUCs of the radiomics-radiologic model in the training and validation cohorts were 0.946 and 0.867, respectively. The AUCs of the combined model in the training and validation cohorts were 0.960 and 0.867, respectively. Conclusion: NCCT models based on multivariable, radiomics features and ML algorithm could improve the discrimination of early HE. The combined model was the best recommended model to identify sICH patients at risk of early HE.

      • Expression of bcl-2 and p53 in Induction of Esophageal Cancer Cell Apoptosis by ECRG2 in Combination with Cisplatin

        Song, Hai-Yan,Deng, Xiao-Hui,Yuan, Guo-Yan,Hou, Xin-Fang,Zhu, Zhen-Dong,Zhou, Li,Ren, Ming-Xin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.3

        Aim: To investigate the mechanisms of induction of apoptosis of esophageal cancer cells by esophageal cancer-related gene 2 (ECRG2) in combination with cisplatin (DDP). Methods: Hoechest staining was performed to analyze the effects of single ECRG2 and ECRG2 in combination with DDP on apoptosis of EC9706 cells. The expression levels of p53 and bcl-2 mRNA and protein were determined by RT-PCR and Western blotting, respectively. Results: The number of apoptotic cells after the treatment with ECRG2 in combination with DDP for 24 hours was more than that after the treatment with single ECRG2. RT-PCR and Western blotting showed that the expression levels of bcl-2 mRNA and protein were both down-regulated, while p53 mRNA and protein were both up-regulated in the cells treated with ECRG2 in combination with DDP compared with those given ECRG2 alone. Conclusion: ECRG2 in combination with DDP can enhance the apoptosis of EC9706 cells, possibly by down-regulating bcl-2 expression and up-regulating p53.

      • SCIESCOPUSKCI등재

        Energy-efficient Power Allocation based on worst-case performance optimization under channel uncertainties

        ( Xin Song Li Dong ),( Xue Huang Lei Qin ),( Xiuwei Han ) 한국인터넷정보학회 2020 KSII Transactions on Internet and Information Syst Vol.14 No.11

        In the practical communication environment, the accurate channel state information (CSI) is difficult to obtain, which will cause the mismatch of resource and degrade the system performance. In this paper, to account for the channel uncertainties, a robust power allocation scheme for a downlink Non-orthogonal multiple access (NOMA) heterogeneous network (HetNet) is designed to maximize energy efficiency (EE), which can ensure the quality of service (QoS) of users. We conduct the robust optimization model based on worse-case method, in which the channel gains belong to certain ellipsoid sets. To solve the non-convex non-liner optimization , we transform the optimization problem via Dinkelbach method and sequential convex programming, and the power allocation of small cell users (SCUs) is achieved by Lagrange dual approach. Finally, we analysis the convergence performance of proposed scheme. The simulation results demonstrate that the proposed algorithm can improve total EE of SCUs, and has a fast convergence performance.

      • SCIESCOPUSKCI등재
      • KCI등재

        A Cloud-Edge Collaborative Computing Task Scheduling and Resource Allocation Algorithm for Energy Internet Environment

        ( Xin Song ),( Yue Wang ),( Zhigang Xie ),( Lin Xia ) 한국인터넷정보학회 2021 KSII Transactions on Internet and Information Syst Vol.15 No.6

        To solve the problems of heavy computing load and system transmission pressure in energy internet (EI), we establish a three-tier cloud-edge integrated EI network based on a cloud-edge collaborative computing to achieve the tradeoff between energy consumption and the system delay. A joint optimization problem for resource allocation and task offloading in the three-tier cloud-edge integrated EI network is formulated to minimize the total system cost under the constraints of the task scheduling binary variables of each sensor node, the maximum uplink transmit power of each sensor node, the limited computation capability of the sensor node and the maximum computation resource of each edge server, which is a Mixed Integer Non-linear Programming (MINLP) problem. To solve the problem, we propose a joint task offloading and resource allocation algorithm (JTOARA), which is decomposed into three subproblems including the uplink transmission power allocation sub-problem, the computation resource allocation sub-problem, and the offloading scheme selection sub-problem. Then, the power allocation of each sensor node is achieved by bisection search algorithm, which has a fast convergence. While the computation resource allocation is derived by line optimization method and convex optimization theory. Finally, to achieve the optimal task offloading, we propose a cloud-edge collaborative computation offloading schemes based on game theory and prove the existence of Nash Equilibrium. The simulation results demonstrate that our proposed algorithm can improve output performance as comparing with the conventional algorithms, and its performance is close to the that of the enumerative algorithm.

      • 논문 : 1910~1945년 길림지역의 한인과 독립운동 개황

        염송심 ( Song Xin Lian ) 단국사학회 2012 史學志 Vol.45 No.-

        이 글은 길림지역에 이주한 한인들의 생활상과 독립운동을 살펴본 것이다. 길림지역은 국치를 전후한 시기에 많은 한인들이 이주하여 정착한 지역이었다. 이러한 한인들은 한일 병탄 이후 망국노로의 전락을 원치 않았던 식자층과 일본의 식민통치에 의해 파산한 농민들이 주를 이루었다. 이러한 까닭에 이 지역은 1919년 3·1운동 이후 민족독립운동의 근거지가 되었다. 한인들은 주로 두 가지 경로를 통해 길림지역으로 이주하였다. 첫째 함경도에서 두만강을 건너 길림성 동부지역으로 들어와, 그 중 일부가 서쪽으로 이동해 연길, 돈화, 교하를 거쳐 길림지역에 도착하는 경로이다. 또 다른 한 가지는 경상도, 전라도, 충청도, 평안도에서 압록강을 건너 요녕성과 길림성 동남부 산악지역를 지난 후 용녕성 봉성, 관전, 환인을 거쳐 길림성의 혼강, 류하, 해룡, 화전을 경유해 최종적으로 길림지역에 도착하는 경로이다. 길림지역에 도착한 후 한인들 대부분은 심양 -길림 간 철도의 동측 산악지역과 장춘 -도문, 길림 -하얼빈 철도 연선지역에 정착해 생활하였다. 이주한인들은 1907년 이전시기부터 길림시내에 정착하여 살고 있었다고 한다. 이들 한인들은 지속적으로 길림시와 주변지역에 정착하여 만주사변 전까지 주로 농업에 종사하면서 황무지를 개간하고 수전 경영을 하였다. 위만주국 설립 이후에는 길림시 외곽지역과 주변 농촌의 한인들이 대거 길림시 시내로 피난해와 정미소, 음식점, 옷가게, 이발소 등의 서비스업에 종사하기 시작하였다. 이 외에 두 곳의 주식회사와 약국, 병원이 있었다. 이러한 산업들은 일위정부(日僞政府)와 타협해 얻은 산물이었으리라 생각된다. 한인들은 길림지역으로 이주한 뒤 서당과 학교를 건립하기 시작했으나, 경비의 부족으로 인해 유지에 큰 어려움을 겪었다. 대부분의 학교들은 독립운동가와의 밀접한 관계를 맺고 반일민족교육을 진행하고 있었기 때문에 일본 침략기관에 의해 탄압을 받고 문을 닫게 되는 경우가 많았다. 만주사변 이전, 길림지역은 한인독립운동의 중심지 중 한 곳으로, 의열단, 정의부, 서로군정서 등 많은 독립운동단체들이 이곳에서 활동하였다. 반일애국인사들이 창건한 학교와 정미소는 독립운동가들의 연락기점이 되었다. 만주국이 수립된 이후, 대부분의 민족주의자들은 일위정부(日僞政府)와 타협하거나 혹은 관내지역으로 이주 하였다. 급진적 인사들은 공산주의단체에 가입해 중국공산당의 지도하에서 반제반봉건적 투쟁을 계속하였다. 1945년 8월 15일 일본이 투항하고 난 후, 정치목적을 가지고 길림지역으로 이주한 한인(많은 친일인사들을 포함) 대부분은 한국으로 돌아갔고, 광범위한 하층 군중들만 여전히 길림에 남아 중화인민공화국의 공민이 되었다. This study examines that the living statement and the independence movements of Korean migrants in Jilin province where many Koreans settled before and after the National Humiliation. Jilin became a base of the independence movements after the March First Movement in 1919, because the migrants were mostly the literate stratum who would not become a ruined people and the bankrupt farmers by Japanese colonial rule. Korean migrants moved to Jilin mainly through two routes. First, it is to cross Duman(Tumen) River from Hamkyung-do province to the eastern area in Jilin province; then, some of these shifted to the West and reached Jilin City via Yanji, Dunhua and Jiaohe. The other is to cross Amrok(Yalu) River from Gyeongsang-do, Jeolla-do, Chungcheong-do and Pyeongan-do province, pass the mountain regions of Southeast Liaoning and Jilin, go by Fengcheng, Kuandian and Huanren, and finally arrive at Jilin City by way of Hun River, Liuhe, Hai Long and Huadian. After arrival in Jilin, the most Koreans rooted in the eastern mountain regions of the Shenyang-Jilin railway line and the area along the railway of the Changchun-Tumen and Jilin-Harbin line. Korean migrants began living in the downtown of Jilin City before 1907. Having continually settled in and around Jilin, they were generally occupied with agriculture, developed the wild land, and managed paddy fields until Manchurian Incident. Since the establishment of Manchukuo, a large number of Koreans fled from the remote and surrounding farm area to the downtown, starting to engage in service industry such as rice mill, restaurant, clothing and barbering businesses. Except these, there were two of stock companies, pharmacies and hospitals; however, it is thought that they may be the product of compromising with the Japanese puppet government. Korean migrants founded village schools of classical learning(Seodang) and modern-educational schools after moving to Jilin, but were in heavy difficulties to maintain with the lack of funds. As the most schools were connected with the leaders of independence movements, and progressed the anti-Japanese national education, it was frequent to be closed by the pressure of Japanese invasive organisations. Before Manchurian Incident Jilin was one of the centres for Korean independence movement. There were a great number of organisations for the independence, for example Uiyeoldan, Jeongeui-bu and Seoro-gunjeongseo. The schools and the rice mills set up by anti-Japanese patriots became junction of the independence movement activists. After the establishment of Manchukuo the most nationalists compromised with the Japanese puppet government, or moved to the Chinese mainland. The radicalists joined in communist organisations, keeping struggles under the leading of Chinese Communist Party. Since Japan`s surrender in August Fifteenth, 1945, some Koreans moving to Jilin with political purpose―including the pro-Japanese collaborator―had mostly returned to Korea; the wide-ranging populace has yet remained in Jilin, being citizens of the People`s Republic of China.

      • KCI등재

        Magnetic Resonance Venography Findings of Obstructed Hepatic Veins and the Inferior Vena Cava in Patients with Budd-Chiari Syndrome

        Ru-Xin Song,Shi-Feng Cai,Shuang Ma,Zhi-Ling Liu,Yong-Hao Gai,Chun-Qing Zhang,Guang-Chuan Wang 대한영상의학회 2018 Korean Journal of Radiology Vol.19 No.3

        Objective: This study aimed to illustrate the magnetic resonance venography (MRV) manifestations of obstructed hepatic veins (HVs), the inferior vena cava (IVC), and accessory hepatic veins (AHVs) in patients with Budd-Chiari syndrome (BCS) and to evaluate the visualization capacity of MRV in the diagnosis of BCS. Materials and Methods: Fifty-two patients with chronic BCS were included in this study. All patients were examined via MRV performed with a 3T system following injections of gadolinium-diethylene triamine pentaacetic acid (Gd-DTPA) or Gdethoxibenzyl-DTPA. HV and IVC lesions were classified, and their characteristics were described. HV cord-like occlusions detected via MRV were compared using ultrasonography (US). Digital subtraction angiography (DSA) was performed as a contrast in the MRV detection of IVC lesions. The HVs draining collaterals, mainly AHVs, were carefully observed. HV lesions were classified as segmental stenosis, segmental occlusion, membranous stenosis, membranous occlusion, cord-like occlusion, or non-visualized. Except for patent IVCs, IVC lesions were classified as segmental occlusion, segmental stenosis, membranous occlusion, membranous stenosis, and hepatomegaly-induced stenosis. Results: All patients (52/52, 100%) showed HV lesions of different degrees. MRV was inferior to US in detecting cord-like occlusions (6 vs. 19, χ2 = 11.077, p < 0.001). Dilated AHVs, including 50 (50/52, 96.2%) caudate lobe veins and 37 (37/52, 71.2%) inferior HV and AHV lesions, were well-detected. There were no significant differences in detecting segmental lesions and thrombosis between MRV and DSA (χ2 = 0.000, p1 = 1.000, p2 = 1.000). The capacity of MRV to detect membranous lesions was inferior to that of DSA (7 vs. 15, χ2 = 6.125, p = 0.013). Conclusion: In patients with BCS, MRV can clearly display the lesions in HVs and the IVC, as well as in AHVs, and it has diagnostic and therapeutic value.

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