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Xiaoxie Gao,Zhaoxi Hong,Yixiong Feng,Tianyue Wang,Ye Li,Jianrong Tan 대한기계학회 2021 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.35 No.10
Reducing the disturbance of parameter fluctuations to the system is very important to the robustness of stamping product quality. In this paper, a 6-sigma robust optimization design method based on residual error and radial basis interpolation is proposed to weaken the negative influence of parameter fluctuations. Not only the key controllable parameters but also the key noise parameters are considered by grey relational analysis (GRA) to screen the parameters that have an important influence on the stamping quality. In order to reflect the relationship between key parameters and forming quality more precisely, the polynomial response surface model is improved based on residual error and radial basis function (RBF), and solved by the multi-population co-evolutionary immune algorithm (MPCEIA). Moreover, the solution of deterministic optimization is designed with 6-sigma robust optimization to improve the robustness of the system to the parameter fluctuations. Finally, the method is applied to the design of a complex automobile cover part, proving its effectiveness and reliability.
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Continuity of Care in Chronic Diseases: A Concept Analysis by Literature Review
Hu, Jingjing,Wang, Yuexia,Li, Xiaoxi 한국간호과학회 2020 Journal of Korean Academy of Nursing Vol.50 No.4
Purpose: This study aimed to utilize concept analysis to obtain a better understanding of the concept of “continuity of care” in chronic diseases. Methods: The concept of continuity of care was analyzed using the Walker and Avant method. Covering literature in English from 1930 to 2018, the data sources included CINAHL Complete, Academic Search Complete, MEDLINE, PsyARTICLES, Health Source: Nursing/Academic Edition, Google Scholar, Science Direct, and the Cochrane Library. Results: A comprehensive definition of concept of continuity of care was developed based on a systematic search and synthesis. The key defining attributes were identified as (a) care over time, (b) the relationship between an individual patient and a care team, (c) information transfer, (d) coordination, and (e) meeting changing needs. The antecedents of continuity of care were having a chronic disease, inexperienced with disease management, a poorly coordinated healthcare system, and medical care limitations. The consequences of continuity of care were decreasing hospital admissions, reducing costs, reducing emergency room visits, improving the quality of life, improving patient satisfaction, and delivering good healthcare. Conclusion: The thorough concept analysis provides insight into the nature of “continuity of care” in chronic diseases and also helps ground the concept in healthcare.
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Continuity of Care in Chronic Diseases: A Concept Analysis by Literature Review
Jingjing Hu,Yuexia Wang,Xiaoxi Li 한국간호과학회 2020 Journal of Korean Academy of Nursing Vol. No.
Purpose: This study aimed to utilize concept analysis to obtain a better understanding of the concept of “continuity of care” in chronic diseases. Methods: The concept of continuity of care was analyzed using the Walker and Avant method. Covering literature in English from 1930 to 2018, the data sources included CINAHL Complete, Academic Search Complete, MEDLINE, PsyARTICLES, Health Source: Nursing/ Academic Edition, Google Scholar, Science Direct, and the Cochrane Library. Results: A comprehensive definition of concept of continuity of care was developed based on a systematic search and synthesis. The key defining attributes were identified as (a) care over time, (b) the relationship between an individual patient and a care team, (c) information transfer, (d) coordination, and (e) meeting changing needs. The antecedents of continuity of care were having a chronic disease, inexperienced with disease management, a poorly coordinated healthcare system, and medical care limitations. The consequences of continuity of care were decreasing hospital admissions, reducing costs, reducing emergency room visits, improving the quality of life, improving patient satisfaction, and delivering good healthcare. Conclusion: The thorough concept analysis provides insight into the nature of “continuity of care” in chronic diseases and also helps ground the concept in healthcare.
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Baodong Liu,Zhenan Zhang,Minqiang Zhang,Xiaoxi Wang 한국강구조학회 2019 International Journal of Steel Structures Vol.19 No.3
This paper presents a comparative study on the composite structure of Corrugated Steel Plate (CSP) with normal and rubberized concrete. One CSP-normal-concrete plate and two CSP arch structures composited with diff erent concretes are established. A theoretical section-property deduction is derived, which demonstrated that the fl exural rigidity of such composite structure increased notably. Static and dynamic mechanical experiments are also conducted. Experimental results agree with expectations, and the measured results on plate structures verifi ed the eff ectiveness of the analytical and numerical solutions. Comparing the defl ection of two composite arches shows that the rubberized concrete composite arch has smaller fl exural and compressive stiff nesses, resulting in larger defl ection. The rubberized concrete composite arch has higher steel stress, lower concrete stress and better energy-dissipating capacity compared with the normal concrete composite arch. Therefore, the CSP-rubberized concrete composite structure is more suitable for anti-shock and earthquake-resistant structures.
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Lei Chen,Haipeng He,Mian Wang,Xiaoxi Li,Henghui Yin 한국조직공학과 재생의학회 2017 조직공학과 재생의학 Vol.14 No.4
Expanded polytetrafluoroethylene (ePTFE) polymers do not support endothelialization because of nonconductive characteristics towards cellular attachment. Inner surface modification of the grafts can improve endothelialization and increase the long-term patency rate of the ePTFE vascular grafts. Here we reported a method of inner-surface modification of ePTFE vascular graft with extracellular matrix (ECM) and CD34 monoclonal antibodies (CD34 mAb) to stimulate the adhesion and proliferation of circulating endothelial progenitor cells on ePTFE graft to enhance graft endothelialization. The inner surface of ECM-coated ePTFE grafts were linked with CD34 mAb in the presence of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide (EDC/NHS) solution and the physicochemical properties, surface morphology, biocompatibility, and hemocompatibility of the grafts were studied. The hydrophilicity of CD34 mAb-coated graft inner surface was significantly improved. Fourier transform infrared spectroscopy analysis confirmed ECM and CD34 mAb cross-linking in the ePTFE vascular grafts with our method. Scanning electron microscopy analysis showed protein layer covering uniformly on the inner surface of the modified grafts. The cell-counting kit-8 (CCK-8) assay confirmed that the modified graft has no obvious cytotoxicity. The modified graft showed a low hemolytic rate (0.9%) in the direct contact hemolysis test, suggesting the modification improved hemocompatibility of biopolymers. The modification also decreased adhesion of platelets, while significantly increased the adhesion of endothelial cells on the grafts. We conclude that our method enables ePTFE polymers modification with ECM and CD34 mAb, facilitates endothelialization, and inhibits platelet adhesion on the grafts, thus may increase the long-term patency rate of the prosthetic bypass grafts.
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