论国家出资企业所出资企业解散清算中的几个问题

Zhang Xiao fei(张,晓,飞,) 충북대학교 법학연구소 2014 法學硏究 Vol.25 No.1

The problems in the dissolving and liquidation of state-invested enterprises are related to the actual operating condition of the management system of state-owned assets. Local government usually treats state-invested enterprise and its invested enterprise as enterprise group for the management. Same like state-invested enterprises, if the dissolving and liquidation of the enterprise invested by state-invested enterprise is led by the local government, the process of dissolving and liquidation actually is the realization of government's micro economic management function. It follows the operation logic of public power, but departs from the operation of private laws. And it also ignores the enterprise as well as its creditors, stakeholders and the interests of shareholders. Legality and Legitimacy of this kind of dissolving and liquidation should be questioned. 国家出资企业所出资企业解散清算中所遇到的问题与企业国有资产管理体制的实际运行状态有关,地方政府常常是把国家出资企业与国家出资企业所出资企业作为企业集团整体来管理的。同国家出资企业一样,国家出资企业所出资企业解散清算程序如果由地方政府所主导,解散清算过程其实就是政府微观经济管理职能的实现过程,遵循公权力的运行逻辑,偏离私法的运行轨迹,忽视了企业的主体性,漠视了企业债权人、利害关系人、股东的正当权益,解散清算行为的合法性、正当性应受质疑。

rs10505474 and rs7837328 at 8q24 Cumulatively Confer Risk of Prostate Cancer in Northern Han Chinese

Zhang, Lin-Lin,Sun, Liang,Zhu, Xiao-Quan,Xu, Yong,Yang, Kuo,Yang, Fan,Yang, Yi-Ge,Chen, Guo-Qiang,Fu, Ji-Cheng,Zheng, Chen-Guang,Li, Ying,Mu, Xiao-Qiu,Shi, Xiao-Hong,Zhao, Fan,Wang, Fei,Yang, Ze,Wang, Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7

Aims: Genome-wide association studies (GWAS) have identified several risk variants for prostate cancer (pCa) mainly in Europeans, which need to be further verified in other racial groups. We selected six previously identified variants as candidates and to define the association with PCa in Northern Han Chinese. Methods: 749 subjects from Beijing and Tianjin in Northern China were included. Six variants (rs10505474, rs7837328, rs4242384, rs7813, rs486907 and rs1058205) were genotyped by high resolution melting (HRM) assays. The individual and cumulative contribution for of the risk of PCa and clinical covariates were analyzed. Results: Among the six candidate variants, onlyrs10505474, and rs7837328, both locating at 8q24 region, were associated with PCa in our population.rs10505474 (A) was associated with PCa ($OR_{recessive}=1.56$, p=0.006); and rs7837328 (A) was associated with PCa ($OR_{dominant}=1.38$, p=0.042/$OR_{recessive}=1.99$, p=0.003). Moreover, we observed a cumulative effects between them ($p_{trend}=2.58{\times}10^{-5}$). The joint population attributable risk showed the two variants might account for 71.85% of PCa risk. In addition, we found the homozygotes of rs10505474 (A) and rs7837328 (A) were associated with PCa clinical covariants (age at onset, tumor stage, respectively) ($p_{age}=0.046$, $P_{tumorstage}=0.048$). Conclusion: rs10505474 (A) and rs7387328 (A) at 8q24 are associated with PCa and cumulatively confer risk, suggesting the two variations could determine susceptibility to PCa in the Northern Chinese Han population.

Anomalous magnetization jumps in granular Pb superconducting films

Zhang An-Lei,Jiang Wan-Yan,Chen Xing-Hong,Zhang Xiao-Ke,Lu Wen-Lai,Chen Fei,Feng Zhen-Jie,Cao Shi-Xun,Zhang Jin-Cang,Ge Jun-Yi 한국물리학회 2022 Current Applied Physics Vol.35 No.-

In granular superconductors, the grain boundaries are closely related to the vortex dynamics and the macroscopic superconducting properties. In our research, Pb films with different grain sizes were prepared by tuning the substrate temperature. With the grain size decreasing, Pb films are prone to feature the anomalous magnetization jumps in the M − T curves, while in the M − H curves flux avalanche happens. Both phenomena appear in the same region of the H − T phase diagram and thus are considered to have the same origin. The further theoretical analysis shows that with grain size decreasing the pinning mechanism evolves from a mixed δTc and δl pinning to the δl pinning mechanism. The results shed light on the study of pinning mechanism for granular superconductors and is beneficial to the potential application of manipulating vortex pinning by regulation of intrinsic defects.

A small hairpin RNA targeting myeloid cell leukemia-1 enhances apoptosis in host macrophages infected with Mycobacterium tuberculosis

Fei-yu Wang,Yu-qing Zhang,Xin-min Wang,Chan Wang,Xiao-fang Wang,Jiang-dong Wu,Fang Wu,Wan-jiang Zhang,Le Zhang 한국미생물학회 2016 The journal of microbiology Vol.54 No.4

Myeloid cell leukemia-1 (Mcl-1) plays an important role in various cell survival pathways. Some studies indicated that the expression of Mcl-1 was upregulated in host cells during infection with the virulent Mycobacterium tuberculosis strain, H37Rv. The present study was designed to investigate the effect of inhibiting Mcl-1 expression both in vivo and in vitro on apoptosis of host macrophages infected with M. tuberculosis using a small hairpin (sh)RNA. Mcl-1 expression was detected by the real time-polymerase chain reaction, western blotting, and immunohistochemistry. Flow cytometry and transmission electron microscopy were used to measure host macrophage apoptosis. We found elevated Mcl-1 levels in host macrophages infected with M. tuberculosis H37Rv. The expression of Mcl-1 was downregulated efficiently in H37Rv-infected host macrophages using shRNA. Knockdown of Mcl-1 enhanced the extent of apoptosis in H37Rv-infected host macrophages significantly. The increased apoptosis correlated with a decrease in M. tuberculosis colony forming units recovered from H37Rv-infected cells that were treated with Mcl-1-shRNA. Reducing Mcl-1 accumulation by shRNA also reduced accumulation of the anti-apoptotic gene, Bcl-2, and increased expression of the pro-apoptotic gene, Bax, in H37Rv-infected host macrophages. Our results showed that specific knockdown of Mcl-1 expression increased apoptosis of host macrophages significantly and decreased the intracellular survival of a virulent strain of M. tuberculosis. These data indicate that interference with Mcl-1 expression may provide a new avenue for tuberculosis therapy.

Electrically tunable dielectric properties of Ba0.6Sr0.4TiO3-MgO composite ceramics.

Xiao-Fei Zhang 한양대학교 세라믹연구소 2013 Journal of Ceramic Processing Research Vol.14 No.3

40 wt.% Ba0.6Sr0.4TiO3-60 wt.% MgO composite ceramics were prepared from Ba0.6Sr0.4TiO3 powder synthesized by a citrate method and fine MgO powder. The composite ceramics sintered at 1150-1270 o C attained reasonable densification. The structure and dielectric properties of the specimens were investigated. The results showed an important role of sintering temperature in controlling the microstructure and dielectric properties of the specimens. Sintering at 1250 o C was determined to be preferred in terms of the nonlinear dielectric properties of the specimens under bias electric field. The specimen sintered at 1250 o C attained a dielectric constant (εr) of 207 and a dielectric loss (tanδ) of 0.11% at 10 kHz together with a tunability of 18.5% and a figure of merit (FOM) of 168 at 10 kHz and 30 kV/cm. It was found that the nonlinear dielectric properties of the specimen measured in continuous cycles of bias electric field sweep were dependent on field history. The phenomenon is qualitatively explained in relation to the polarization reorientation of polar nano-regions (PNRs) in Ba0.6Sr0.4TiO3 phase of the composite specimen.

Influence of substrate bias on microstructure and morphology of ZrN thin films deposited by arc ion plating

ZHANG, Min,HU, Xiao-gang,YANG, Xiao-xu,XU, Fei-fei,KIM, Kwang-Ho,SHAO, Zhi-gang Elsevier 2012 Transactions of Nonferrous Metals Society of China Vol.22 No.suppl1

Association of Six Susceptibility Loci with Prostate Cancer in Northern Chinese Men

Zhang, Yu-Rong,Xu, Yong,Yang, Kuo,Liu, Ming,Wei, Dong,Zhang, Yao-Guang,Shi, Xiao-Hong,Wang, Jian-Ye,Yang, Fan,Wang, Xin,Liang, Si-Ying,Zhao, Cheng-Xiao,Wang, Fei,Chen, Xin,Sun, Liang,Zhu, Xiao-Quan,Zh Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12

Background/Aim: Six prostate cancer (PCa) susceptibility loci were identified in a genome-wide association study (GWAS) in populations of European decent. However, the associations of these 6 single-nucleotide polymorphisms (SNPs) with PCa has remained tobe clarified in men in Northern China. This study aimed to explore the loci associated with PCa risk in a Northern Chinese population. Methods: Blood samples and clinical information of 289 PCa patients and 288 controls from Beijing and Tianjin were collected. All risk SNPs were genotyped using polymerase chain reaction (PCR)-high resolution melting curve technology and gene sequencing. Associations between PCa and clinical covariates (age at diagnosis, prostate-specific antigen [PSA], Gleason score, tumor stage, and level of aggressiveness) and frequencies of alleles and genotypes of these SNPs were analyzed using genetic statistics. Results: Among the candidate SNPs, 11p15 (rs7127900, A) was associated with PCa risk (P = 0.02, odds ratio [OR] = 1.64, 95% confidence interval [CI] = 1.09-2.46). Genotypes showed differences between cases and controls on 11p15 (rs7127900, A), 11q13 (rs7931342, T), and HNF1B (rs4430796, A) (P = 0.03, P = 0.01, and P = 0.04, respectively). The genotype TG on 11q13 (rs7931342, T) was positively associated with an increased Gleason score (P = 0.04, OR = 2.15, 95% CI = 1.02-4.55). Patients carrying TG on 17q24 (rs1859962, G) were negatively associated with an increased body mass index (BMI) (P = 0.03, OR = 0.44, 95% CI = 0.21-0.92) while those with AG on HNF1B (rs4430796, A) were more likely to have PSA increase (P = 0.002). Conclusion: Our study suggests that 11p15 (rs7127900, A) could be a susceptibility locus associated with PCa in Northern Chinese. Genotype TG on 11q13 (rs7931342, T) could be related to an increased Gleason score, AG on HNF1B (rs4430796, A) could be associated with PSA increase, and TG on 17q24 (rs1859962, G) could be negatively associated with an increased BMI in Chinese men with PCa.

Enhanced postoperative cancer therapy by iron-based hydrogels

Haomeng Zhang,Meng Zhang,Xinyu Zhang,Yuan Gao,Yanling Ma,Hongyu Chen,Jipeng Wan,Changzhong Li,Fei Wang,Xiao Sun 한국생체재료학회 2022 생체재료학회지 Vol.26 No.2

Surgical resection is a widely used method for the treatment of solid tumor cancers. However, the inhibition of tumor recurrence and metastasis are the main challenges of postoperative tumor therapy. Traditional intravenous or oral administration have poor chemotherapeutics bioavailability and undesirable systemic toxicity. Polymeric hydrogels with a three-dimensional network structure enable on-site delivery and controlled release of therapeutic drugs with reduced systemic toxicity and have been widely developed for postoperative adjuvant tumor therapy. Among them, because of the simple synthesis, good biocompatibility, biodegradability, injectability, and multifunctionality, ironbased hydrogels have received extensive attention. This review has summarized the general synthesis methods and construction principles of iron-based hydrogels, highlighted the latest progress of iron-based hydrogels in postoperative tumor therapy, including chemotherapy, photothermal therapy, photodynamic therapy, chemo-dynamic therapy, and magnetothermal-chemical combined therapy, etc. In addition, the challenges towards clinical application of iron-based hydrogels have also been discussed. This review is expected to show researchers broad perspectives of novel postoperative tumor therapy strategy and provide new ideas in the design and application of novel iron-based hydrogels to advance this sub field in cancer nanomedicine.

Optimization of maximum torque output in the wide speed range of a PMSM traction control system

Zhang, Weiwei,Xiao, Fei,Liu, Jilong,Mai, Zhiqin,Li, Chaoran The Korean Institute of Power Electronics 2020 JOURNAL OF POWER ELECTRONICS Vol.20 No.1

This paper introduces a permanent magnet synchronous motor maximum torque control method for the wide speed range of a traction control system. This method tracks the maximum torque per ampere operating point and generates a d-axis current command according to the injection of a high-frequency angle signal to the current. This method is parameter independent when looking for the maximum torque per ampere operating point. By not injecting any real signal to a permanent magnet synchronous motor, this method does not increase the amount of copper and iron losses resulting from real signal injection. To obtain a maximum torque output in a wide speed range, this method considers the maximum amplitude limits of voltage and current when the traction motor runs in a flux weakening control field. This method is also robust to current and voltage harmonics, speed mutations, and torque disturbances. Experiment and analysis are conducted on a permanent magnet synchronous motor traction control system prototype under various operating conditions to verify the effectiveness of this method.

Declutching control of a point absorber with direct linear electric PTO systems

Zhang, Xian-Tao,Yang, Jian-Min,Xiao, Long-Fei Techno-Press 2014 Ocean systems engineering Vol.4 No.1

Declutching control is applied to a hemispherical wave energy converter with direct linear electric Power-Take-Off systems oscillating in heave direction in both regular and irregular waves. The direct linear Power-Take-Off system can be simplified as a mechanical spring and damper system. Time domain model is applied to dynamics of the hemispherical wave energy converter in both regular and irregular waves. And state space model is used to replace the convolution term in time domain equation of the heave oscillation of the converter due to its inconvenience in analyzing the controlled motion of the converters. The declutching control strategy is conducted by optimal command theory based on Pontryagin's maximum principle to gain the controlled optimum sequence of Power-Take-Off forces. The results show that the wave energy converter with declutching control captures more energy than that without control and the former's amplitude and velocity is relatively larger. However, the amplification ratio of the absorbed power by declutching control is only slightly larger than 1. This may indicate that declutching control method may be inapplicable for oscillating wave energy converters with direct linear Power-Take-Off systems in real random sea state, considering the error of prediction of the wave excitation force.