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      • Research on the Relationship Between Serum Levels of Inflammatory Cytokines and Non-small Cell Lung Cancer

        Song, Xiao-Yun,Zhou, Shi-Jie,Xiao, Ning,Li, Yun-Song,Zhen, De-Zhi,Su, Chong-Yu,Liu, Zhi-Dong Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.8

        Aims: This study was conducted to evaluate the levels of TNF-${\alpha}$, IL-6, IL-8 and VEGF in serum of patients with non- small cell lung cancer, for assessing their possible diagnostic and prognostic roles. Methods: We enrolled 48 patients newly diagnosed with non-small cell lung cancer and 40 healthy controls. TNF- ${\alpha}$, IL-6 and IL-8 levels were measured in the serum of all the subjects with specific radioimmunoassay kits, while EGF was analyzed by sandwich enzyme immunoassay techniques. Results: A statistically significant difference was observed between lung cancer patients and the control group regarding the values of TNF-${\alpha}$, IL-6, IL-8 and VEGF in serum. Moreover, TNF-${\alpha}$, IL-8 and VEGF levels were higher in patients with advanced stages compared to early stages. In addition, higher serum levels of TNF-${\alpha}$, IL-6, IL-8 and VEGF were found in smokers than in non-smokers, both in patients and controls. Conclusion: Serum levels of TNF-${\alpha}$, IL-6, IL-8 and VEGF were all elevated in lung cancer patients, suggesting that inflammatory cytokines could be jointly used as a screening tool. Though TNF-${\alpha}$, IL-8 and VEGF levels were related to advanced disease, long-term survival studies of NSCLC patients should be performed to confirm whether they can act as biomarkers of advanced disease. In addition, smoking would be an important contributor to the processes of inflammation and lung cancer.

      • SCIESSCISCOPUSKCI등재

        Reliability and Validity of Chinese Version of the Perceived Competence Scale for Disaster Mental Health Workforce: A Cross-Sectional Study

        Qingqing Xiao(Qingqing Xiao),Xiaozhen Song(Xiaozhen Song),Xuehua Huang(Xuehua Huang),Xiandong Meng(Xiandong Meng) 대한신경정신의학회 2023 PSYCHIATRY INVESTIGATION Vol.20 No.3

        Objective This study aimed to translate the English version of the Perceived Competence Scale for Disaster Mental Health Workforce (PCS-DMHW) into Chinese, and to test its reliability and validity in Chinese mental health workers.Methods With the consent of Professor Choi, Keimyung University, Korea, and the authorization of the scale, the English version of PCS-DMHW was translated, retranslated and culturally debugged to form the Chinese version of PCS-DMHW. The general information questionnaire and the Chinese version of PCS-DMHW scale were used to investigate 706 mental health workforce from 9 tertiary hospitals in Sichuan province in China from March 24, 2020 to April 14, 2020. The Cronbach’s α coefficient was used to evaluate the internal consistency reliability of the scale, and the test-retest correlation coefficient r was used to evaluate the test-retest reliability of the scale. The content validity indexes (CVI) and exploratory factor analysis (EFA) was used separately for evaluating the content validity and structure validity of the scale.Results The Cronbach’s α coefficient of the Chinese version of PCS-DMHW total scale, individual competences and organizational competences subscale was 0.978, 0.956, and 0.964, respectively. The test-retest reliability of the total scale, individual competences and organizational competences subscale was 0.949, 0.932 and 0.927, respectively. The item-level CVI of all scale were ranged from 0.833-1.000, the scale-level CVI (S-CVI)/universal agreement of the total scale, individual competences and organizational competences subscale was 0.833, 0.875, and 0.857, respectively, and the S-CVI/average was 0.972, 0.979, and 0.976, respectively. EFA showed that two principal components were extracted from the subscale of individual competences and organizational competences.Conclusion The Chinese version of PCS-DMHW has good reliability and validity, and can be widely used in China.

      • KCI등재

        Construction of National Fitness Online Platform System Based on Mobile Internet Technology

        Xiao, Haibin,Cao Yang⋅Song,Song. Jeho 한국스포츠학회 2020 한국스포츠학회지 Vol.18 No.2

        최근 몇 년 사이 국민체력이 화두가 되고 있다. 어떻게 하면 건강하고 효과적으로 운동할 수 있을지가 시급히 해결 해야 할 수 있다. 정보 공유 플랫폼으로서 인터넷 플랫폼은 편리하고 빠른 피트니스 안내 서비스를 제공할 수 있으며 국민 피트니스 활동에 중요한 역할을 한다. 매스 스포츠 피트니스 가이드에 인터넷을 적용하면 피트니스 지식의 편리한 획득에 도움이 되며, 매스 피트니스의 과학적 특성과 정확성을 높일 수 있다. 모바일 인터넷을 기반으로 하는 국민 피트니스 온라 인 플랫폼은 모바일 인터넷 기술이 결합된 플랫폼으로 시민들이 피트니스 기록, 교육 동영상, 결과 피드백 등 3가지 측면에 서 피트니스 과제를 완성할 수 있도록 지원한다. 사용자 피트니스 비디오의 추천을 완료하기 위해 플랫폼은 비디오 기반의 협업 필터링 추천 알고리즘을 사용한다. 이 플랫폼은 인기 패널티와 추천 콘텐츠의 풍부함을 증가시켰다. 플랫폼을 통해 현재의 피트니스 가이드 네트워크 플랫폼에 존재하는 문제점을 발굴하고, 타겟팅된 개발 대책과 제안을 제시한다. In recent years, national fitness has become a hot topic. How to exercise healthily and effectively is an urgent problem to be solved. As an information sharing platform, the Internet platform can provide convenient and fast fitness guidance services and plays an important role in national fitness activities. The application of the Internet in mass sports fitness guidance is conducive to the convenient acquisition of fitness knowledge, and can increase the scientific nature and accuracy of mass fitness. The national fitness online platform based on mobile internet is a combination of mobile internet technology, which assists citizens to complete fitness tasks from three aspects: fitness records, teaching videos and result feedback. To complete the recommendation of user fitness videos, the platform uses video-based collaborative filtering recommendation algorithm. The platform has increased popularity penalties and the richness of recommended content. Through the platform, the problems existing in the current fitness guidance network platform are discovered, and targeted development countermeasures and suggestions are put forward.

      • KCI등재

        An Investigation into the Characteristics of a Novel Rotatable Pantograph Catenary System for High-Speed Trains

        Xiao Song,Luo Yuanpei,Wu Jingchi,Zhang Can,Rao Yang,Wu Guangning,Deng Zhida,Sykulski Jan K. 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.3

        High speed trains receive traction electrical energy from a high-voltage catenary via a pantograph catenary system (PCS). As the velocity of trains increases, the traditional PCSs face signifi cant challenges, such as strong aero resistance under highspeed conditions, severe electrochemical corrosion caused by poor contact between the pantograph strip and the catenary, harmful wear both on the pantograph strip and the contact wire produced by high-speed sliding friction between them, etc. The eff ectiveness and reliability of the PCS has a direct impact on the performance and safety of the HTS power supply. In order to alleviate some of these bottleneck eff ects related to the operation of the currently used PCSs, especially under high-speed conditions, this paper proposes a novel confi guration where rotatable pantograph rollers replace the currently used pantograph strips. As the sliding friction is now replaced by rotating friction, this has numerous benefi ts, such as less friction heat, better heat dispersion and improved catenary-tracking performance. Moreover, should the whole system be modularized, it could adapt to diff erent levels of traction power through adjusting the number of rollers.

      • KCI등재

        The characteristic analysis of the operational overvoltage caused by the vacuum circuit breakers on High-speed trains

        Xiao Song,Tong Mengyuan,Rao Yang,Li Yuhang,Ye Zhizong,Shen Yixiang,Hou Hao,Gao Guoqiang,Wu Guangning,Jin Yaoyao,Zhou Jie,Liu Jie 대한전기학회 2022 Journal of Electrical Engineering & Technology Vol.17 No.1

        Along with the operating velocity and traction power increasing continuously, the issue related to the safety and reliability of the high-voltage traction power system for high-speed trains have gradually been exposed during the practical service process. When the train passes a neutral section settled roughly per 15 km between two neighboring substations, the on-board vacuum circuit breaker (VCB) must to be operated for changing the input powers with diff erent phases. At the moment of switching on or off the VCB, the arc between the contacts in the arc-extinguishing chamber may be triggered, which tends to result in the operational overvoltage. Due to numerous inductances and capacitances existing in the traction power supply system, the overvoltage may lead to high-frequency electromagnetic oscillation spreading along the transmission routes. The on-board high-voltage equipments within the power supply system may suff er from the impulse brought from the VCB operational overvoltage frequently, which is possible to cause the insulation aging or breakdown issue. To investigate the characteristic of the operational overvoltage of VCBs, a ‘train-rail-catenary’ power supply model is built based on the measured impedance parameters, which has been verifi ed by the experimental tests. The generating mechanism with the infl uence factors of the operational overvoltage when switching on or off the VCB has been explored, meanwhile the distribution of the train body overvoltage on each carriage has also been presented.

      • KCI등재

        Steam reforming of α-methylnaphthalene as a model compound of biomass tar over Ni-based catalyst for hydrogen-rich gas

        Xiao Lv,Jun Xiao,Tingting Sun,Xiaodong Huo,Min Song,Laihong Shen 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.2

        Tar is a barrier to limit the development of biomass gasification. Catalytic steam reforming experiments using α-methylnaphthalene (MNP) as a model tar compound were carried out in the two-stage reactor system (TSR). Based on response surface methodology, the effects of TSR temperatures and the molar ratio of steam to carbon (S/C) on MNP reforming performances were analyzed using the Li-modified Ni-based catalyst (NBC). The results show that the proper introduction of H2 is able to improve significantly the MNP conversion, specially at lower temperatures. Furthermore, it is more appropriate for the modified catalysts by Li and Mg to be loaded in the first reactor due to their significant promotion to hydrocracking reactions, and it is favorable to place the Ni/Al catalyst in the second reactor for H2-rich gas. Additionally, the carbon deposition resistance of the NBC modified by Li exhibits better than that of the NBC modified by Mg.

      • Bioinformatic Prediction of SNPs within miRNA Binding Sites of Inflammatory Genes Associated with Gastric Cancer

        Song, Chuan-Qing,Zhang, Jun-Hui,Shi, Jia-Chen,Cao, Xiao-Qin,Song, Chun-Hua,Hassan, Adil,Wang, Peng,Dai, Li-Ping,Zhang, Jian-Ying,Wang, Kai-Juan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2

        Polymorphisms in miRNA binding sites have been shown to affect miRNA binding to target genes, resulting in differential mRNA and protein expression and susceptibility to common diseases. Our purpose was to predict SNPs (single nucleotide polymorphisms) within miRNA binding sites of inflammatory genes in relation to gastric cancer. A complete list of SNPs in the 3'UTR regions of all inflammatory genes associated with gastric cancer was obtained from Pubmed. miRNA target prediction databases (MirSNP, Targetscan Human 6.2, PolymiRTS 3.0, miRNASNP 2.0, and Patrocles) were used to predict miRNA target sites. There were 99 SNPs with MAF>0.05 within the miRNA binding sites of 41 genes among 72 inflammation-related genes associated with gastric cancer. NF-${\kappa}B$ and JAK-STAT are the two most important signaling pathways. 47 SNPs of 25 genes with 95 miRNAs were predicted. CCL2 and IL1F5 were found to be the shared target genes of hsa-miRNA-624-3p. Bioinformatic methods could identify a set of SNPs within miRNA binding sites of inflammatory genes, and provide data and direction for subsequent functional verification research.

      • KCI등재

        New MIT Control Strategy Combined with Iterative Learning Control

        Xiao Song,Jingzhuo Shi 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.7

        As the pioneer of model reference adaptive control (MRAC) method, MIT control strategy is still used in various practical applications. In this paper, MIT is applied to the speed control of ultrasonic motor, trying to use a relatively simple control method to obtain good control performance. However, MIT control strategy only adjusts the gain, so it is difficult to achieve a large correction of the system’s dynamic characteristics, which limits the actual performance. To solve this problem, two improved MIT control strategies based on iterative learning are proposed in this paper to enhance the control performance. Both methods adopt the P-type iterative learning control (P-ILC) strategy with simplest structure. One is to connect the P-ILC controller with the MIT controller in series to adjust the given value of the MIT controller in real time. The other is to use the P-ILC controller to adjust the adaptive gain of the MIT controller in real time, so as to enhance its control freedom and adaptive ability to deal with complex objects. The experimental results show that the proposed control strategies have their own advantages and can significantly improve the control performance after finite iterative learning processes.

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